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Article ; Online: Letter to the editor regarding the publication by Munro, van Dijk & Couto (2024), "Developing symptom-specific dietary leaflets to address radiotherapy side effects using an eDelphi method".

Grima, R / Azzopardi, A / Coppini, C / Borg, M R

Radiography (London, England : 1995)

2024 Volume 30, Issue 2, Page(s) 706–707

MeSH term(s)	Humans ; Radiation Oncology
Language	English
Publishing date	2024-02-27
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1289102-2
ISSN	1532-2831 ; 1078-8174
ISSN (online)	1532-2831
ISSN	1078-8174
DOI	10.1016/j.radi.2024.02.010
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Article: Clinical Impact of Rapid Bacterial Microbiological Identification with the MALDI-TOF MS.

Uzuriaga, Miriam / Leiva, José / Guillén-Grima, Francisco / Rua, Marta / Yuste, José R

Antibiotics (Basel, Switzerland)

2023 Volume 12, Issue 12

Abstract: Rapid microbiological reports to clinicians are related to improved clinical outcomes. We conducted a 3-year quasi-experimental design, specifically a pretest-posttest single group design in a university medical center, to evaluate the clinical impact of ...

Abstract	Rapid microbiological reports to clinicians are related to improved clinical outcomes. We conducted a 3-year quasi-experimental design, specifically a pretest-posttest single group design in a university medical center, to evaluate the clinical impact of rapid microbiological identification information using MALDI-TOF MS on optimizing antibiotic prescription. A total of 363 consecutive hospitalized patients with bacterial infections were evaluated comparing a historical control group (CG) (n = 183), in which the microbiological information (bacterial identification and antibiotic susceptibility) was reported jointly to the clinician between 18:00 h and 22:00 h of the same day and a prospective intervention group (IG) (n = 180); the bacterial identification information was informed to the clinician as soon as it was available between 12:00 h and 14:00 h and the antibiotic susceptibility between 18:00 h and 22:00 h). We observed, in favor of IG, a statistically significant decrease in the information time (11.44 h CG vs. 4.48 h IG (
Language	English
Publishing date	2023-11-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics12121660
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Article ; Online: A scoping review of person-centred care strategies used in diagnostic Nuclear Medicine.

Champendal, M / Borg Grima, K / Costa, P / Andersson, C / Baun, C / Gorga, R G / Murphy, S / Kedves, A / Santos, A / Geao, A

Radiography (London, England : 1995)

2024 Volume 30, Issue 2, Page(s) 448–456

Abstract: Introduction: Person-centred care (PCC) emphasises the need for the health care professional to prioritise individual patient needs, thereby fostering a collaborative and emphatic environment that empowers patients to actively participate in their own ... ...

Abstract	Introduction: Person-centred care (PCC) emphasises the need for the health care professional to prioritise individual patient needs, thereby fostering a collaborative and emphatic environment that empowers patients to actively participate in their own care. This article will explore the purpose of PCC in Nuclear Medicine (NM), while discussing strategies that may be used to implement PCC during diagnostic NM examinations performed on adult patients. Methods: The scoping review was conducted in accordance with the Joanna Briggs Institute methodology. The search was performed on PubMed, Embase and Cinhal in June 2023 and included studies in English, Spanish, Portuguese and Italian. The research equation combined keywords and Medical Subject Heading terms (MeSH) related to person-centred care (PCC), for all types of nuclear medicine diagnostic examinations performed. Three independent review authors screened all abstracts and titles, and all eligible full-text publications were included in this scoping review. Results: Fifty-three articles, published between 1993 and 2022, met the inclusion criteria for this scoping review. Seven articles were published in 2015 while 56.6 % of all included studies were performed in Europe. Most studies (n = 39/53) focused on the patients only, with the identified patient benefits being: improve patient experience (67.9 %), increase patient comfort (13.2 %), increase patient knowledge (5.7 %), reduction of patient anxiety (9.4 %) and reduction of waiting/scan time (3.8 %). Conclusion: The scoping review identified a lack of research investigating the use of person-centred care strategies in NM. Future research will focus on using an international survey to explore this topic in nuclear medicine departments overseas. Implications for practice: By applying PCC principles, the NM professional can improve the patient care pathway and increase patient satisfaction, leading to enhanced clinical outcomes.
MeSH term(s)	Adult ; Humans ; Nuclear Medicine ; Health Personnel ; Radionuclide Imaging ; Patient-Centered Care ; Patient Satisfaction
Language	English
Publishing date	2024-01-10
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	1289102-2
ISSN	1532-2831 ; 1078-8174
ISSN (online)	1532-2831
ISSN	1078-8174
DOI	10.1016/j.radi.2023.12.011
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Article: Sleep Regularity and Mortality: A Prospective Analysis in the UK Biobank.

Cribb, Lachlan / Sha, Ramon / Yiallourou, Stephanie / Grima, Natalie A / Cavuoto, Marina / Baril, Andree-Ann / Pase, Matthew P

medRxiv : the preprint server for health sciences

2023

Abstract: Background: Irregular sleep-wake timing may cause circadian disruption leading to several chronic age-related diseases. We examined the relationship between sleep regularity and risk of all-cause, cardiovascular disease (CVD), and cancer mortality in 88, ...

Abstract	Background: Irregular sleep-wake timing may cause circadian disruption leading to several chronic age-related diseases. We examined the relationship between sleep regularity and risk of all-cause, cardiovascular disease (CVD), and cancer mortality in 88,975 participants from the prospective UK Biobank cohort. Methods: The sleep regularity index (SRI) was calculated as the probability of an individual being in the same state (asleep or awake) at any two time points 24 hours apart, averaged over 7-days of accelerometry (range 0-100, with 100 being perfectly regular). The SRI was related to the risk of mortality in time-to-event models. Findings: The mean sample age was 62 years (SD, 8), 56% were women, and the median SRI was 60 (SD, 10). There were 3010 deaths during a mean follow-up of 7.1 years. Following adjustments for demographic and clinical variables, we identified a non-linear relationship between the SRI and all-cause mortality hazard ( Conclusions: Irregular sleep-wake patterns are associated with higher mortality risk. Funding: National Health and Medical Research Council of Australia (GTN2009264; GTN1158384), National Institute on Aging (AG062531), Alzheimer's Association (2018-AARG-591358), and the Banting Fellowship Program (#454104).
Language	English
Publishing date	2023-08-15
Publishing country	United States
Document type	Preprint
DOI	10.1101/2023.04.14.23288550
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Article ; Online: Sleep regularity and mortality: a prospective analysis in the UK Biobank.

Cribb, Lachlan / Sha, Ramon / Yiallourou, Stephanie / Grima, Natalie A / Cavuoto, Marina / Baril, Andree-Ann / Pase, Matthew P

eLife

2023 Volume 12

Abstract	Background: Irregular sleep-wake timing may cause circadian disruption leading to several chronic age-related diseases. We examined the relationship between sleep regularity and risk of all-cause, cardiovascular disease (CVD), and cancer mortality in 88,975 participants from the prospective UK Biobank cohort. Methods: The sleep regularity index (SRI) was calculated as the probability of an individual being in the same state (asleep or awake) at any two time points 24 hr apart, averaged over 7 days of accelerometry (range 0-100, with 100 being perfectly regular). The SRI was related to the risk of mortality in time-to-event models. Results: The mean sample age was 62 years (standard deviation [SD], 8), 56% were women, and the median SRI was 60 (SD, 10). There were 3010 deaths during a mean follow-up of 7.1 years. Following adjustments for demographic and clinical variables, we identified a non-linear relationship between the SRI and all-cause mortality hazard ( Conclusions: Irregular sleep-wake patterns are associated with higher mortality risk. Funding: National Health and Medical Research Council of Australia (GTN2009264; GTN1158384), National Institute on Aging (AG062531), Alzheimer's Association (2018-AARG-591358), and the Banting Fellowship Program (#454104).
MeSH term(s)	Humans ; Female ; Middle Aged ; Male ; Biological Specimen Banks ; Sleep ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; United Kingdom/epidemiology ; Neoplasms
Language	English
Publishing date	2023-11-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2687154-3
ISSN	2050-084X ; 2050-084X
ISSN (online)	2050-084X
ISSN	2050-084X
DOI	10.7554/eLife.88359
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Article: Factors Associated with Pneumonia in Patients Hospitalized with COVID-19 and the Role of Vaccination.

Zizza, Antonella / Sedile, Raffaella / Bagordo, Francesco / Panico, Alessandra / Guido, Marcello / Grassi, Tiziana / Banchelli, Federico / Grima, Pierfrancesco

Vaccines

2023 Volume 11, Issue 8

Abstract: Patients with COVID-19 can develop different forms of the illness with more or less severe symptoms. A 2-year retrospective cohort study was conducted to evaluate the factors associated with the development of pneumonia in patients hospitalized with ... ...

Abstract	Patients with COVID-19 can develop different forms of the illness with more or less severe symptoms. A 2-year retrospective cohort study was conducted to evaluate the factors associated with the development of pneumonia in patients hospitalized with COVID-19 from March 2020 to February 2022. A total of 385 patients (59.0% males) with a mean age of 69.0 ± 16.0 years were included. At hospital admission, 318 patients (82.6%) reported one or more comorbidities, namely 201 (52.2%) subjects were affected by hypertension, 98 (25.5%) type 2 diabetes, 84 (21.8%) obesity, 36 (9.4%) cancer, and 14 (3.6%) suffered from kidney disease and were being treated with dialysis, and 76 (19.7%) resulted in being vaccinated with a higher prevalence of BNT162b2 vaccine (15.0%). Pneumonia was diagnosed in 276 (71.7%) patients. Multivariate regression analysis showed that pneumonia in COVID-19 patients was positively associated with type 2 diabetes (OR 1.81; 95% CI 1.00-3.27), obesity (OR 2.52; 95% CI 1.27-4.98), and negatively with hypertension (OR 0.58; 95% CI 0.35-0.96). Vaccination against SARS-CoV-2 resulted in a strongly protective factor against the development of pneumonia in COVID-19 patients (OR 0.49; 95% CI 0.28-0.85).
Language	English
Publishing date	2023-08-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines11081342
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Article: A Proactive Approach to Identify the Exposure Risk to COVID-19: Validation of the Pandemic Risk Exposure Measurement (PREM) Model Using Real-World Data.

Grima, Simon / Rupeika-Apoga, Ramona / Kizilkaya, Murat / Romānova, Inna / Dalli Gonzi, Rebecca / Jakovljevic, Mihajlo

Risk management and healthcare policy

2021 Volume 14, Page(s) 4775–4787

Abstract: Purpose: To statistically validate the PREM (Pandemic Risk Exposure Measurement) model devised in a previous paper by the authors and determine the model's relationship with the level of current COVID-19 cases (NLCC) and the level of current deaths ... ...

Abstract	Purpose: To statistically validate the PREM (Pandemic Risk Exposure Measurement) model devised in a previous paper by the authors and determine the model's relationship with the level of current COVID-19 cases (NLCC) and the level of current deaths related to COVID-19 (NLCD) based on the real country data. Methods: We used perceived variables proposed in a previous study by the same lead authors and applied the latest available real data values for 154 countries. Two endogenous real data variables (NLCC) and (NLCD) were added. Data were transformed to measurable values using a Likert scale of 1 to 5. The resulting data for each variable were entered into SPSS (Statistical Package for the Social Sciences) version 26 and Amos (Analysis of a Moment Structures) version 21 and subjected to statistical analysis, specifically exploratory factor analysis, Cronbach's alpha and confirmatory factor analysis. Results: The results obtained confirmed a 4-factor structure and that the PREM model using real data is statistically reliable and valid. However, the variable Q14 - hospital beds available per capita (1000 inhabitants) had to be excluded from the analysis because it loaded under more than one factor and the difference between the factor common variance was less than 0.10. Moreover, its Factor 1 and Factor 3 with NLCC and Factor 1 with NLCD showed a statistically significant relationship. Conclusion: Therefore, the developed PREM model moves from a perception-based model to reality. By proposing a model that allows governments and policymakers to take a proactive approach, the negative impact of a pandemic on the functioning of a country can be reduced. The PREM model is useful for decision-makers to know what factors make the country more vulnerable to a pandemic and, if possible, to manage or set tolerances as part of a preventive measure.
Language	English
Publishing date	2021-11-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2495128-6
ISSN	1179-1594
ISSN	1179-1594
DOI	10.2147/RMHP.S341500
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Article: Cancellation of Auxetic Properties in F.C.C. Hard Sphere Crystals by Hybrid Layer-Channel Nanoinclusions Filled by Hard Spheres of Another Diameter.

Narojczyk, Jakub W / Wojciechowski, Krzysztof W / Smardzewski, Jerzy / Imre, Attila R / Grima, Joseph N / Bilski, Mikołaj

Materials (Basel, Switzerland)

2021 Volume 14, Issue 11

Abstract: The elastic properties of f.c.c. hard sphere crystals with periodic arrays of nanoinclusions filled by hard spheres of another diameter are the subject of this paper. It has been shown that a simple modification of the model structure is sufficient to ... ...

Abstract	The elastic properties of f.c.c. hard sphere crystals with periodic arrays of nanoinclusions filled by hard spheres of another diameter are the subject of this paper. It has been shown that a simple modification of the model structure is sufficient to cause very significant changes in its elastic properties. The use of inclusions in the form of joined (mutually orthogonal) layers and channels showed that the resulting tetragonal system exhibited a complete lack of auxetic properties when the inclusion spheres reached sufficiently large diameter. Moreover, it was very surprising that this hybrid inclusion, which can completely eliminate auxeticity, was composed of components that, alone, in these conditions,
Language	English
Publishing date	2021-06-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma14113008
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Article ; Online: A Proactive Approach to Identify the Exposure Risk to COVID-19

Grima S / Rupeika-Apoga R / Kizilkaya M / Romānova I / Dalli Gonzi R / Jakovljevic M

Risk Management and Healthcare Policy, Vol Volume 14, Pp 4775-

Validation of the Pandemic Risk Exposure Measurement (PREM) Model Using Real-World Data

2021 Volume 4787

Abstract: ... of Kragujevac, Kragujevac, Serbia; 7Department of Public Health and Healthcare Named After N.A. Semashko, I.M ... Simon Grima, 1 Ramona Rupeika-Apoga, 2 Murat Kizilkaya, 3 Inna Romānova, 2 Rebecca Dalli Gonzi, 4 ... GrimaUniversity of Malta, Msida, MSD, 2080, MaltaTel +356 79 651 410Email simon.grima@um.edu.mtPurpose ...

Abstract	Simon Grima, 1 Ramona Rupeika-Apoga, 2 Murat Kizilkaya, 3 Inna Romānova, 2 Rebecca Dalli Gonzi, 4 Mihajlo Jakovljevic 5– 7 1Department of Insurance, Faculty of Economics, Management and Accountancy, University of Malta, Msida, Malta; 2Faculty of Business, Management and Economics, University of Latvia, Riga, Latvia; 3Department of Economics, Faculty of Economics and Administrative Sciences, Ardahan University, Ardahan, Turkey; 4Department of Construction & Property Management, University of Malta, Msida, MSD, 2080, Malta; 5Institute of Comparative Economic Studies ICES, Faculty of Economics, Hosei University, Tokyo, Japan; 6Department of Global Health Economics and Policy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; 7Department of Public Health and Healthcare Named After N.A. Semashko, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, RussiaCorrespondence: Simon GrimaUniversity of Malta, Msida, MSD, 2080, MaltaTel +356 79 651 410Email simon.grima@um.edu.mtPurpose: To statistically validate the PREM (Pandemic Risk Exposure Measurement) model devised in a previous paper by the authors and determine the model’s relationship with the level of current COVID-19 cases (NLCC) and the level of current deaths related to COVID-19 (NLCD) based on the real country data.Methods: We used perceived variables proposed in a previous study by the same lead authors and applied the latest available real data values for 154 countries. Two endogenous real data variables (NLCC) and (NLCD) were added. Data were transformed to measurable values using a Likert scale of 1 to 5. The resulting data for each variable were entered into SPSS (Statistical Package for the Social Sciences) version 26 and Amos (Analysis of a Moment Structures) version 21 and subjected to statistical analysis, specifically exploratory factor analysis, Cronbach’s alpha and confirmatory factor analysis.Results: The results obtained confirmed a 4-factor structure and that the PREM model using real data ...
Keywords	covid-19 ; pandemic risk exposure ; prem ; proactive ; vulnerability ; Public aspects of medicine ; RA1-1270
Subject code	306
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Dove Medical Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spatial characterization of near-surface structure and meltwater runoff conditions across the Devon Ice Cap from dual-frequency radar reflectivity

K. Chan / C. Grima / A. Rutishauser / D. A. Young / R. Culberg / D. D. Blankenship

The Cryosphere, Vol 17, Pp 1839-

2023 Volume 1852

Abstract: ... slab thickness throughout the Devon Ice Cap percolation zone ranges from 4.2 to 5.6 m. This implies ...

Abstract	Melting and refreezing processes in the firn of the Devon Ice Cap control meltwater infiltration and runoff across the ice cap, but their full spatial extent and effect on near-surface structure is difficult to measure with surface-based traverses or existing satellite remote sensing. Here, we derive the coherent component of the near-surface return from airborne ice-penetrating radar surveys over the Devon Ice Cap, Canadian Arctic, to characterize firn containing centimeter- to meter-thick ice layers (i.e., ice slabs) formed from refrozen meltwater in firn. We assess the use of dual-frequency airborne ice-penetrating radar to characterize the spatial and vertical near-surface structure of the Devon Ice Cap by leveraging differences in range resolution of the radar systems. Comparison with reflectivities using a thin layer reflectivity model, informed by surface-based radar and firn core measurements, indicates that the coherent component is sensitive to the near-surface firn structure composed of quasi-specular ice and firn layers, limited by the bandwidth-constrained radar range resolution. Our results suggest that average ice slab thickness throughout the Devon Ice Cap percolation zone ranges from 4.2 to 5.6 m. This implies conditions that can enable lateral meltwater runoff and potentially contribute to the total surface runoff routed through supraglacial rivers down glacier. Together with the incoherent component of the surface return previously studied, our dual-frequency approach provides an alternative method for characterizing bulk firn properties, particularly where high-resolution radar data are not available.
Keywords	Environmental sciences ; GE1-350 ; Geology ; QE1-996.5
Subject code	550
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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