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Article: Short-pulsed Q-switched fiber laser using graphene oxide quantum dots based as saturable absorber.

Zaca-Morán, P / Gomez, Celia L / Morán, O Zaca / Ortega-Mendoza, J G / Pola-López, E S

2023 Volume 9, Issue 10, Page(s) e20136

Abstract: In this work, we report the experimental study of a Q-switched optical fiber laser based on graphene oxide quantum dots (GOQDs) as saturable absorber (SA). GOQDs are fabricated by carbonization and exfoliation electrospun polyacrylonitrile (PAN) fibers. ... ...

Abstract	In this work, we report the experimental study of a Q-switched optical fiber laser based on graphene oxide quantum dots (GOQDs) as saturable absorber (SA). GOQDs are fabricated by carbonization and exfoliation electrospun polyacrylonitrile (PAN) fibers. The results of Fourier Transform Infrared Spectroscopy (FTIR) showed bands caused by the CHs and C[bond, double bond]O groups associated with the GOQDs. The Raman spectrum showed the typical G and D bands of GOQDs. The size of the GOQDs, calculated by Transmission Electron Microscopy (TEM) was 6 nm; additionally, by high resolution TEM (HRTEM), an interplanar distance of 0.19 nm corresponding to the (002) direction of the graphene oxide was calculated. The SA was achieved using the photodeposition technique of the GOQDs onto the core of a single-mode optical fiber. The nonlinear characterization (NLC) of the GOQDs was carried out using the P-scan technique with a high-gain erbium-doped fiber amplifier (EDFA) at a wavelength of 1550 nm. The obtained results showed a saturable absorption behavior with a value of
Language	English
Publishing date	2023-09-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e20136
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Approach to Tibial Shaft Nonunions: Diagnosis and Management.

Wellings, Elizabeth P / Moran, Steven L / Tande, Aaron J / Hidden, Krystin A

The Journal of the American Academy of Orthopaedic Surgeons

2024 Volume 32, Issue 6, Page(s) 237–246

Abstract: The tibia is the most common long bone at risk for nonunion with an annual incidence ranging from 12% to 19%. This topic continues to be an area of research as management techniques constantly evolve. A foundational knowledge of the fundamental concepts, ...

Abstract	The tibia is the most common long bone at risk for nonunion with an annual incidence ranging from 12% to 19%. This topic continues to be an area of research as management techniques constantly evolve. A foundational knowledge of the fundamental concepts, etiology, and risk factors for nonunions is crucial for success. Treatment of tibial shaft nonunions often requires a multidisciplinary effort. This article provides guidance based on the most recent literature that can be used to aid the treating provider in the diagnosis, workup, and management of tibial shaft nonunions.
MeSH term(s)	Humans ; Tibia ; Tibial Fractures/diagnosis ; Tibial Fractures/therapy ; Tibial Fractures/complications ; Fractures, Ununited/diagnosis ; Fractures, Ununited/etiology ; Fractures, Ununited/therapy ; Treatment Outcome ; Risk Factors ; Retrospective Studies ; Fracture Healing ; Fracture Fixation, Intramedullary/methods
Language	English
Publishing date	2024-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-23-00453
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Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 274: Show issues

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Article ; Online: Pulsed laser ablation synthesis of fresh Te nanoparticles for matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) applications.

Novotný, Karel / Krempl, Ivo / Pečinka, Lukáš / Moráň, Lukáš / Vaňhara, Petr / Havel, Josef

Talanta

2024 Volume 274, Page(s) 126061

Abstract: This work aims to demonstrate the potential of pulsed laser ablation synthesis (PLA) of tellurium nanoparticles (Te NPs) for use in matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) applications. An experimental laboratory setup ... ...

Abstract	This work aims to demonstrate the potential of pulsed laser ablation synthesis (PLA) of tellurium nanoparticles (Te NPs) for use in matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) applications. An experimental laboratory setup for PLA synthesis of fresh Te NPs was designed to prevent unwanted aggregation of uncoated Te NPs and avoid the need to use additional modifiers. Performing pulsed laser ablation synthesis in liquid (PLAL) using acetone was found to be the optimal way of preparing Te NPs. Another possibility is to use commercially available laser ablation devices for laser ablation - inductively coupled plasma mass spectrometry (LA-ICP-MS) to perform PLA in a helium atmosphere, but this approach is less efficient and results in the formation of unwanted larger particles. The prepared Te NPs were studied using the transmission electron microscopy (TEM) and dynamic light scattering (DLS) methods. TEM images showed the formation of Te NP nanochains composed of many crystallized Te NPs with sizes ranging from 8 to 15 nm. The various size distributions of the synthesized Te NPs identified using the DLS method correspond to the size distributions of aggregations rather than individual Te NPs. The synthesized Te NPs were used for a pilot study of their possible use with the MALDI-MS technique. An important effect was observed when Te NPs were used to perform a MALDI-MS analysis of the α-cyclodextrin (α-CD) and cucurbit[7]uril (CB7) macrocycles, which consisted in a decline in the formation of matrix adducts. Furthermore, several changes in MALDI-MS mass spectra of intact cells and a positive effect of Te NPs on the crystallization of the MALDI-MS matrix were observed.
Language	English
Publishing date	2024-04-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1500969-5
ISSN	1873-3573 ; 0039-9140
ISSN (online)	1873-3573
ISSN	0039-9140
DOI	10.1016/j.talanta.2024.126061
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Article: Reduced Graphene Oxide Aerogels Cartridges for Solid Phase Extraction of Benzotriazoles.

Flores-López, Samantha L / Arenillas, Ana / Mikšík, Ivan / Menéndez, J Angel / Montes-Morán, Miguel A

Materials (Basel, Switzerland)

2023 Volume 16, Issue 6

Abstract: UV-benzotriazoles have been identified as water micropollutants that cause serious problems for human health and the environment. Their low concentration in water bodies complicates their detection by direct water analysis, slowing the corrective actions ...

Abstract	UV-benzotriazoles have been identified as water micropollutants that cause serious problems for human health and the environment. Their low concentration in water bodies complicates their detection by direct water analysis, slowing the corrective actions to avoid bioaccumulation. In this regard, the use of graphene-based materials with a high affinity for non-polar molecules has been demonstrated to be a potential tool for the optimal separation and concentration of this type of molecules in solid phase extraction (SPE) processes. This work evaluates the potential of novel reduced graphene oxide aerogels (rGO) as extractants of mixtures of three UV-benzotriazoles in water at low concentrations. These rGO aerogels incorporate graphenic domains into a tough structure of polymeric chains by adding graphene oxide during the synthesis of resorcinol-formaldehyde gels. Aerogels with a different content and ordering of graphenic domains were obtained and characterized using Raman, XRD, SEM and nitrogen adsorption isotherms (-196 °C). The rGO aerogels that performed better as solid phase extractants were those containing 60% rGO. Aerogels with lower rGO contents (40%) required a high-temperature (2000 °C) treatment to render competitive results. The SPE methodology using selected rGO aerogels was optimized by varying the elution solvent, elution time and volume. The best performances, i.e., recoveries of 80-100% and enrichment factors of 12.5-50, were accomplished when using 0.8 mL of tetrahydrofuran (THF) as an elution solvent. As a result, a fast (10 min) and simple extraction method of UV-benzotriazoles in water was attained, achieving a detection limit of 1 ng mL
Language	English
Publishing date	2023-03-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16062519
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Article ; Online: In Vitro and in Vivo Assays for Testing Retinoids Effect on Intestinal Progenitors' Lineage Commitments.

Gajera, Krishna R / Fair, Kathryn L / Moran, Gordon W / Hannan, Nicholas R F / Huelsken, Joerg / Ordóñez-Morán, Paloma

Methods in molecular biology (Clifton, N.J.)

2023 Volume 2650, Page(s) 53–61

Abstract: The intestine consists of epithelial cells surrounded by a complex environment as mesenchymal cells and the gut microbiota. With its impressive stem cell regeneration capability, the intestine is able to constantly replenish cells lost through apoptosis ... ...

Abstract	The intestine consists of epithelial cells surrounded by a complex environment as mesenchymal cells and the gut microbiota. With its impressive stem cell regeneration capability, the intestine is able to constantly replenish cells lost through apoptosis or abrasion by food passing through. Over the past decade, researchers have identified signaling pathways involved in stem cell homeostasis such as retinoids pathway. Retinoids are also involved in cell differentiation of healthy and cancer cells. In this study, we describe several approaches in vitro and in vivo to further investigate the effect of retinoids on stem cells, progenitors, and differentiated intestinal cells.
MeSH term(s)	Apoptosis ; Biological Assay ; Cell Differentiation ; Intestines ; Retinoids/pharmacology
Chemical Substances	Retinoids
Language	English
Publishing date	2023-06-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-3076-1_5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The endoplasmic reticulum and its signaling pathways - a novel target for multiple myeloma treatment.

Dostálová, A / Vlachová, M / Gregorová, J / Moráň, L / Pečinka, L / Gabrielová, V / Vaňhara, P / Ševčíková, S

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

2023 Volume 37, Issue 6, Page(s) 440–446

Abstract: Background: The endoplasmic reticulum (ER), an organelle composed of a system of cisternae and tubules, is essential for many cellular processes, including protein synthesis and transport. When misfolded proteins accumulate in the ER lumen, ER stress is ...

Title translation	Nový cíl specifické protinádorové léčby mnohočetného myelomu – endoplazmatické retikulum a jeho signální dráhy.
Abstract	Background: The endoplasmic reticulum (ER), an organelle composed of a system of cisternae and tubules, is essential for many cellular processes, including protein synthesis and transport. When misfolded proteins accumulate in the ER lumen, ER stress is induced, and the subsequent response to the disruption of homeostasis is the activation of the unfolded protein response (UPR). The purpose of this process is to restore homeostasis by increasing the capacity of the ER and its ability to fold proteins. Activation of the homeostatic UPR occurs via one of three transmembrane proteins, inositol-requiring enzyme 1a (IRE1a), protein kinase R-like ER kinase (PERK) and activating transcription factor 6 (ATF6). Failure of the attempt to restore homeostasis, on the other hand, leads to the development of terminal UPR and apoptosis via hyperactivation of the same proteins. Activation of UPR has been described in many malignancies, including multiple myeloma (MM), which is characterized by malignant transformation of plasma cells and increased monoclonal immunoglobulin synthesis, where the role of the ER is of particular importance. Despite advances in the treatment of MM, the disease remains difficult to treat and targeting signaling pathways associated with the UPR could, for example, enhance the effect of proteasome inhibitors. Purpose: This review intends to present the molecular response to ER stress under physiological circumstances and in the context of cancer, particularly with regard to potential therapeutic targets in MM.
MeSH term(s)	Humans ; Multiple Myeloma/drug therapy ; Unfolded Protein Response ; Endoplasmic Reticulum Stress ; Signal Transduction ; Endoplasmic Reticulum/metabolism ; Apoptosis
Language	English
Publishing date	2023-10-23
Publishing country	Czech Republic
Document type	Review ; Journal Article
ZDB-ID	1217739-8
ISSN	1802-5307 ; 0862-495X
ISSN (online)	1802-5307
ISSN	0862-495X
DOI	10.48095/ccko2023440
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Zs.A 4181: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Suicidal ideation and depressive symptoms in an urban post-partum maternity setting: a retrospective cohort study.

Moran, L / Sheehan, J D / Roddy, D / Duffy, R M

Irish journal of psychological medicine

2023 Volume 40, Issue 4, Page(s) 566–570

Abstract: Background: Fifteen percent of women worldwide experience depression in the perinatal period. Suicide is now one of the leading causes of maternal mortality in developed countries. Internationally, many healthcare systems screen post-natal women for ... ...

Abstract	Background: Fifteen percent of women worldwide experience depression in the perinatal period. Suicide is now one of the leading causes of maternal mortality in developed countries. Internationally, many healthcare systems screen post-natal women for depressive symptoms and suicidal ideation to facilitate early assessment and intervention. To our knowledge, no Irish data exists on the prevalence of suicidal ideation in this cohort. Aims: To evaluate the prevalence of suicidal ideation and depressive symptoms using the Edinburgh Postnatal Depression Scale (EPDS) in post-natal women attending a large Dublin maternity hospital. Methods: A retrospective cohort study was conducted. Women were randomly selected by delivery date over a 6 month period. Demographic and medical information was collected from their booking visit and discharge summary data. EPDS results at discharge post-partum were examined. Results: Data was collected on 643 women. Post-partum, 19 women (3.4%) had experienced suicidal ideation in the previous 7 days. Just over half of these women also had high EPDS scores (>12). Overall, 29 women (5.2%) screened positive for depression (EPDS score > 12). Conclusions: The rate of suicidal ideation is in line with the published international data and emphasises the need for all clinicians to inquire about such thoughts. Training of midwifery and obstetric staff is required. Maternity units should have a policy on the management of suicidal ideation and risk. The prevalence of depressive symptoms post-partum was comparatively low in our study. This could suggest that antenatal screening and early intervention, which are integral parts of the perinatal mental health service, are effective. However, due to limitations of the study, it could also reflect an under-representation of depressive symptom burden in this cohort.
MeSH term(s)	Female ; Pregnancy ; Humans ; Depression/epidemiology ; Suicidal Ideation ; Retrospective Studies ; Postpartum Period ; Psychiatric Status Rating Scales
Language	English
Publishing date	2023-03-03
Publishing country	England
Document type	Journal Article
ZDB-ID	227751-7
ISSN	2051-6967 ; 0790-9667
ISSN (online)	2051-6967
ISSN	0790-9667
DOI	10.1017/ipm.2023.12
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Zs.A 3174: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Mid-term outcomes of three commonly used surgical reconstructions for scapholunate instability.

van Kampen, Robert J / Coert, J Henk / Moran, Steven L

The Journal of hand surgery, European volume

2023 , Page(s) 17531934231219191

Abstract: This retrospective analysis reports the mid-term (>2 years) outcomes of capsulodesis, (modified) Brunelli tenodesis and bone-ligament-bone reconstruction for scapholunate ligament instability. In total, 60 patients (64 wrists) returned the Patient-Rated ... ...

Abstract	This retrospective analysis reports the mid-term (>2 years) outcomes of capsulodesis, (modified) Brunelli tenodesis and bone-ligament-bone reconstruction for scapholunate ligament instability. In total, 60 patients (64 wrists) returned the Patient-Rated Wrist Evaluation and Disabilities of the Arm, Shoulder, and Hand questionnaires. Of these participants, 42 (46 wrists) returned for a wrist examination and radiographs. In the questionnaire group, the mean follow-up for capsulodesis was 11.8 years, tenodesis 5.9 years and bone-ligament-bone 8.9 years. In the objective outcomes group, the mean follow-up was 10.2 years for capsulodesis, 5.7 for tenodesis and 8.9 for bone-ligament-bone. In all groups, some patients showed radiographic deterioration, which did not always correlate with poor functional outcome. With a mean follow-up greater than 5 years, there was no substantial difference in clinical outcomes and patient-based outcome questionnaires between capsulodesis, tenodesis or bone-ligament-bone reconstruction for the treatment of scapholunate instability. This study emphasizes the need for further research. Surgeons should use the technique that produces the fewest complications.
Language	English
Publishing date	2023-12-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2272801-6
ISSN	2043-6289 ; 1753-1934
ISSN (online)	2043-6289
ISSN	1753-1934
DOI	10.1177/17531934231219191
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Zs.A 1940: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Short-pulsed Q-switched fiber laser using graphene oxide quantum dots based as saturable absorber

P. Zaca-Morán / Celia L. Gomez / O. Zaca Morán / J.G. Ortega-Mendoza / E.S. Pola-López

Heliyon, Vol 9, Iss 10, Pp e20136- (2023)

2023

Abstract	In this work, we report the experimental study of a Q-switched optical fiber laser based on graphene oxide quantum dots (GOQDs) as saturable absorber (SA). GOQDs are fabricated by carbonization and exfoliation electrospun polyacrylonitrile (PAN) fibers. The results of Fourier Transform Infrared Spectroscopy (FTIR) showed bands caused by the CHs and CO groups associated with the GOQDs. The Raman spectrum showed the typical G and D bands of GOQDs. The size of the GOQDs, calculated by Transmission Electron Microscopy (TEM) was 6 nm; additionally, by high resolution TEM (HRTEM), an interplanar distance of 0.19 nm corresponding to the (002) direction of the graphene oxide was calculated. The SA was achieved using the photodeposition technique of the GOQDs onto the core of a single-mode optical fiber. The nonlinear characterization (NLC) of the GOQDs was carried out using the P-scan technique with a high-gain erbium-doped fiber amplifier (EDFA) at a wavelength of 1550 nm. The obtained results showed a saturable absorption behavior with a value of β=−1.178x10−6(m/W) and a non-linear susceptibility of Im(χ(3))≈−1.573x10−7(esu). The experimental results of the SA, based on GOQDs as a switching device in a fiber laser, showed a typical behavior of a Q-switched laser by generating a pulsed emission at a wavelength of 1599 nm, a frequency from 2 to 16 kHz, and a maximum average output power of 1.3 mW.
Keywords	Graphene oxide ; Quantum dots ; Optical fibers ; Nonlinear characterization ; Nonlinear susceptibility ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	535
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Enhancing Australian Mortality Data to Meet Future Health Information Demands.

Eynstone-Hinkins, James / Moran, Lauren

International journal of environmental research and public health

2022 Volume 19, Issue 1

Abstract: The Australian mortality data are a foundational health dataset which supports research, policy and planning. The COVID-19 pandemic necessitated the need for more timely mortality data that could assist in monitoring direct mortality from the virus as ... ...

Abstract	The Australian mortality data are a foundational health dataset which supports research, policy and planning. The COVID-19 pandemic necessitated the need for more timely mortality data that could assist in monitoring direct mortality from the virus as well as indirect mortality due to social and economic societal change. This paper discusses the evolution of mortality data in Australia during the pandemic and looks at emerging opportunities associated with electronic infrastructure such as electronic Medical Certificates of Cause of Death (eMCCDs), ICD-11 and automated coding tools that will form the foundations of a more responsive and comprehensive future mortality dataset.
MeSH term(s)	Australia/epidemiology ; COVID-19 ; Humans ; International Classification of Diseases ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2022-01-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19010603
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