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  1. Book: Nutrition in intensive care medicine

    Singer, Pierre

    beyond physiology

    (World review of nutrition and dietetics ; 105)

    2013  

    Author's details volume ed. Pierre Singer
    Series title World review of nutrition and dietetics ; 105
    Collection
    Keywords Nutritional Support ; Intensive Care / methods ; Patient Care Management ; Intensivmedizin ; Künstliche Ernährung
    Subject Klinische Ernährung
    Language English
    Size XI, 194 S. : graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    Note Includes bibliographical references and indexes ; From mitochondrial disturbances to energy requirements / P. Singer -- Protein metabolism and requirements / G. Biolo -- How to choose the route / I. Grecu -- How to prescribe nutritional support using computers / M.M. Berger -- Oral feeding / A. Alvárez-Falcón, S. Ruiz-Santana -- Enteral nutrition / R. Anbar -- Parenteral nutrition / R. Thibault, C. Pichard -- Can nutrition support interfere with recovery from acute critical illness? / R.C. Schulman, J.I. Mechanick -- Glucose control / J.-C. Preiser -- Glutamine / M. Kim, P.E. Wischmeyer -- Leucine and citrulline : two major regulators of protein turnover / L. Cynober, J.-P. de Bandt -- The surgical/trauma patient / A. Weimann -- Nutrition and sepsis / J. Cohen, W.D.N. Chin -- The renal failure patient / W. Druml -- N-3 fatty acids and -linolenic acid supplementation in the nutritional support of ventilated patients with acute lung injury or acute respiratory distress syndrome / S. Lev, P. Singer -- Obesity / D.C. Frankenfield -- Nutritional imbalances during extracorporeal life support / I. Kagan -- Nutrition in pancreatitis / S.A. McClave -- Which nutritional regimen for the comorbid complex intensive care unit patient? / P. Singer, H. Weinberger, B. Tadmor --Nutrition support for wound healing in the intensive care unit patient / M. Theilla
    HBZ-ID HT017427894
    ISBN 978-3-318-02227-8 ; 9783318022285 ; 3-318-02227-6 ; 3318022284
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: How to prescribe parenteral nutrition the safest way: case by case or using machine learning?

    Singer, Pierre

    Journal of intensive medicine

    2022  Volume 2, Issue 2, Page(s) 67–68

    Language English
    Publishing date 2022-03-30
    Publishing country China
    Document type Editorial
    ISSN 2667-100X
    ISSN (online) 2667-100X
    DOI 10.1016/j.jointm.2022.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nutritional and metabolic management of COVID-19 intensive care patients.

    Singer, Pierre

    Journal of intensive medicine

    2021  Volume 1, Issue 1, Page(s) 31–34

    Abstract: Nutritional and metabolic disturbances are observed in patients critically ill with Coronavirus disease 19 (COVID-19) patients. The aim of this review is to describe these disturbances during the progression of the disease, from the pre-intubation phase ... ...

    Abstract Nutritional and metabolic disturbances are observed in patients critically ill with Coronavirus disease 19 (COVID-19) patients. The aim of this review is to describe these disturbances during the progression of the disease, from the pre-intubation phase through the ventilated condition to the post extubation phase. The analysis of new data describing the prevalence of malnutrition, the modifications in energy expenditure and body composition are guiding medical nutritional therapy to prevent patients from experiencing severe energy deficit and muscle loss. Rehabilitation may be extremely prolonged and therefore, nutrition is mandatory to decrease this recondition period. This review also comments on the European Society of Parenteral and Enteral Nutrition (ESPEN) nutritional statements.
    Language English
    Publishing date 2021-02-05
    Publishing country China
    Document type Journal Article ; Review
    ISSN 2667-100X
    ISSN (online) 2667-100X
    DOI 10.1016/j.jointm.2021.01.004
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  4. Article ; Online: Beyond the limits of indirect calorimetry.

    Singer, Pierre / Statlender, Liran

    European journal of clinical nutrition

    2023  Volume 77, Issue 9, Page(s) 925–926

    MeSH term(s) Humans ; Calorimetry, Indirect ; Energy Metabolism ; Oxygen Consumption
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/s41430-023-01319-2
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    Full text online

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  5. Article ; Online: Response to Letter to the Editor Clinical Nutrition Open Science.

    Reintam Blaser, Annika / Singer, Pierre

    Clinical nutrition (Edinburgh, Scotland)

    2023  Volume 43, Issue 1, Page(s) 299

    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2023.11.015
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  6. Article ; Online: Comment: Early nutrition prescription in critically ill patients-learnings from the FRANS study.

    Berger, Mette M / Singer, Pierre

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 64

    MeSH term(s) Humans ; Critical Illness/therapy ; Critical Illness/mortality ; Prospective Studies ; Cohort Studies ; Nutritional Support ; Nutritional Status
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04346-4
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  7. Article ; Online: Protein metabolism and requirements in the ICU.

    Singer, Pierre

    Clinical nutrition ESPEN

    2020  Volume 38, Page(s) 3–8

    Abstract: The critically ill patient is highly catabolic, loosing significant amounts of protein and muscle. This proteolysis may induce a loss of 20% of the muscle mass in 10 days of hospitalization. Muscle loss may be assessed measuring urinary nitrogen ... ...

    Abstract The critically ill patient is highly catabolic, loosing significant amounts of protein and muscle. This proteolysis may induce a loss of 20% of the muscle mass in 10 days of hospitalization. Muscle loss may be assessed measuring urinary nitrogen excretion, muscle mass by ultrasound, bioimpedance, computerized tomography or MRI. To reduce the negative nitrogen balance, protein can be administrated enterally, or parenterally through amino acids as a part of parenteral nutrition. ESPEN guidelines recommend to administer 1.3 g/kg/day of protein to critically ill patients but this recommendation should be adapted according to clinical conditions. Elderly, obese, trauma, burn, acute kidney injury patients should receive larger amount of protein.
    MeSH term(s) Aged ; Amino Acids ; Critical Illness/therapy ; Humans ; Intensive Care Units ; Parenteral Nutrition ; Parenteral Nutrition, Total
    Chemical Substances Amino Acids
    Language English
    Publishing date 2020-05-31
    Publishing country England
    Document type Journal Article
    ISSN 2405-4577
    ISSN (online) 2405-4577
    DOI 10.1016/j.clnesp.2020.03.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Reply- letter to the editor.

    Singer, Pierre / Theilla, Miriam

    Clinical nutrition (Edinburgh, Scotland)

    2022  Volume 42, Issue 2, Page(s) 244

    Language English
    Publishing date 2022-12-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2022.12.005
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  9. Article ; Online: Metabolic and nutritional aspects in continuous renal replacement therapy.

    Fishman, Guy / Singer, Pierre

    Journal of intensive medicine

    2023  Volume 3, Issue 3, Page(s) 228–238

    Abstract: Nutrition is one of the foundations for supporting and treating critically ill patients. Nutritional support provides calories, protein, electrolytes, vitamins, and trace elements via the enteral or parenteral route. Acute kidney injury (AKI) is a common ...

    Abstract Nutrition is one of the foundations for supporting and treating critically ill patients. Nutritional support provides calories, protein, electrolytes, vitamins, and trace elements via the enteral or parenteral route. Acute kidney injury (AKI) is a common and devastating problem in critically ill patients and has significant metabolic and nutritional consequences. Moreover, renal replacement therapy (RRT), whatever the modality used, also profoundly impacts metabolism. RRT and of the extracorporeal circuit impede 'effect the evaluation of a patient's energy requirements by clinicians. Substrates added and removed within the extracorporeal treatment are not always taken into consideration, making treatment even more challenging. Furthermore, evidence on nutritional support during continuous renal replacement therapy (CRRT) is scarce, and there are no clinical guidelines for nutrition adaptations during CRRT in critically ill patients. Most recommendations are based on expert opinions. This review discusses the complex interaction between nutritional support and CRRT and presents some milestones for nutritional support in critically ill patients on CRRT.
    Language English
    Publishing date 2023-01-30
    Publishing country China
    Document type Journal Article ; Review
    ISSN 2667-100X
    ISSN (online) 2667-100X
    DOI 10.1016/j.jointm.2022.11.001
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  10. Article ; Online: The role of omega-3 polyunsaturated fatty acids in the intensive care unit.

    Singer, Pierre / Calder, Philip C

    Current opinion in clinical nutrition and metabolic care

    2023  Volume 26, Issue 2, Page(s) 129–137

    Abstract: Purpose of review: This review provides an update on the actions of omega-3 polyunsaturated fatty acids (PUFAs) and presents the most recent findings from trials in patients in the intensive care unit (ICU) setting including relevant meta-analyses. Many ...

    Abstract Purpose of review: This review provides an update on the actions of omega-3 polyunsaturated fatty acids (PUFAs) and presents the most recent findings from trials in patients in the intensive care unit (ICU) setting including relevant meta-analyses. Many specialized pro-resolving mediators (SPMs) are produced from bioactive omega-3 PUFAs and may explain many of the beneficial effects of omega-3 PUFAs, although other mechanisms of action of omega-3 PUFAs are being uncovered.
    Recent findings: SPMs resolve inflammation, promote healing and support antiinfection activities of the immune system. Since publication of the ESPEN guidelines, numerous studies further support the use of omega-3 PUFAs. Recent meta-analyses favor the inclusion of omega-3 PUFAs in nutrition support of patients with acute respiratory distress syndrome or sepsis. Recent trials indicate that omega-3 PUFAs may protect against delirium and liver dysfunction in patients in the ICU, although effects on muscle loss are unclear and require further investigation. Critical illness may alter omega-3 PUFA turnover. There has been significant discussion about the potential for omega-3 PUFAs and SPMs in treatment of coronavirus disease 2019.
    Summary: Evidence for benefits of omega-3 PUFAs in the ICU setting has strengthened through new trials and meta-analyses. Nevertheless, better quality trials are still needed. SPMs may explain many of the benefits of omega-3 PUFAs.
    MeSH term(s) Humans ; COVID-19 ; Fatty Acids, Omega-3/therapeutic use ; Inflammation
    Chemical Substances Fatty Acids, Omega-3
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1460178-3
    ISSN 1473-6519 ; 1363-1950
    ISSN (online) 1473-6519
    ISSN 1363-1950
    DOI 10.1097/MCO.0000000000000896
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