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  1. Book ; Online ; E-Book: Neglected plant foods of South Asia

    Ismail, Tariq / Akhtar, Saeed / Lazarte, Claudia E.

    exploring and valorizing nature to feed hunger

    2023  

    Author's details Tariq Ismail, Saeed Akhtar, Claudia E. Lazarte, editors
    Language English
    Size 1 Online-Ressource (481 Seiten)
    Publisher Springer International Publishing AG
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030622880
    ISBN 978-3-031-37077-9 ; 9783031370762 ; 3-031-37077-5 ; 3031370767
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Prevalence of

    Idrees, Muhammad Mubashar / Saeed, Khadija / Shahid, Muhammad Akbar / Akhtar, Muhammad / Qammar, Khadija / Hassan, Javariya / Khaliq, Tayyaba / Saeed, Ali

    Biomedicines

    2023  Volume 11, Issue 3

    Abstract: Methicillin- ... ...

    Abstract Methicillin-resistant
    Language English
    Publishing date 2023-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11030878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Targeted Therapy and Personalized Medicine.

    Saeed, Rida Fatima / Awan, Uzma Azeem / Saeed, Sidra / Mumtaz, Sara / Akhtar, Nosheen / Aslam, Shaista

    Cancer treatment and research

    2023  Volume 185, Page(s) 177–205

    Abstract: Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and prevention. One of the most significant advancements in modern oncology is the shift from an organ-centric strategy to a personalized ... ...

    Abstract Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and prevention. One of the most significant advancements in modern oncology is the shift from an organ-centric strategy to a personalized strategy guided by deep molecular analysis. This shift in view, which focuses on the tumour's precise molecular changes, has paved the way for individualized treatment. Researchers and clinicians are using targeted therapies to select the best treatment available based on the molecular characterization of malignant cancer. In the treatment of a cancer, personalized medicine entails the use of genetic, immunological, and proteomic profiling to provide therapeutic alternatives as well as prognostic information about cancer. In this book, targeted therapies and personalized medicine have been covered for specific malignancies, including latest FDA-approved targeted therapies and it also sheds light on effective anti-cancer regimens and drug resistance. This will help to enhance our ability to conduct individualized health planning, make early diagnoses, and choose optimal medications for each cancer patient with predictable side effects and outcomes in a quickly evolving era. Various applications and tools' capacity have been improved for early diagnosis of cancer and the growing number of clinical trials that choose specific molecular targets reflects this predicament. Nevertheless, there are several limitations that must need to be addressed. Hence, in this chapter, we will discuss recent advancements, challenges, and opportunities in personalized medicine for various cancers, with a specific emphasis on target therapies in diagnostics and therapeutics.
    MeSH term(s) United States ; Humans ; Precision Medicine ; Proteomics ; Drug-Related Side Effects and Adverse Reactions ; Health Planning ; Medical Oncology
    Language English
    Publishing date 2023-06-12
    Publishing country United States
    Document type Journal Article
    ISSN 0927-3042
    ISSN 0927-3042
    DOI 10.1007/978-3-031-27156-4_10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effect of Growth Stages and Lactic Acid Fermentation on Anti-Nutrients and Nutritional Attributes of Spinach (

    Naseem, Adila / Akhtar, Saeed / Ismail, Tariq / Qamar, Muhammad / Sattar, Dur-E-Shahwar / Saeed, Wisha / Esatbeyoglu, Tuba / Bartkiene, Elena / Rocha, João Miguel

    Microorganisms

    2023  Volume 11, Issue 9

    Abstract: Spinach ( ...

    Abstract Spinach (
    Language English
    Publishing date 2023-09-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11092343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reproductive and metabolic toxic effects of polystyrene microplastics in adult female Wistar rats: a mechanistic study.

    Saeed, Anam / Akhtar, Muhammad Furqan / Saleem, Ammara / Akhtar, Bushra / Sharif, Ali

    Environmental science and pollution research international

    2023  Volume 30, Issue 22, Page(s) 63185–63199

    Abstract: Microplastics, such as polystyrene microplastics (PS-MPs), have become an emerging environmental hazard for animals and humans. Long-term exposure to PS-MPs has led to neurotoxicity, reproductive dysfunction, and carcinogenesis. The goal of this study ... ...

    Abstract Microplastics, such as polystyrene microplastics (PS-MPs), have become an emerging environmental hazard for animals and humans. Long-term exposure to PS-MPs has led to neurotoxicity, reproductive dysfunction, and carcinogenesis. The goal of this study was to evaluate the effect of sub-chronic exposure of PS-MPs on metabolic and reproductive functions in female rats. The PS-MPs were prepared by cryogenic technique. The PS-MPs were given orally to female Wistar rats for 45 days at 2.5, 5, and 10 mg/kg/day. The average PS-MPs' size diameter was 876 nm. The PS-MPs administration resulted in a significant decrease in the activity of superoxide dismutase and catalase in the liver and ovary. The effect of PS-MPs on reduced glutathione and lipid peroxidation in the liver and ovarian tissues of rats was statistically insignificant. The PS-MP exposure exhibited an increase in the levels of triglycerides, total cholesterol, and low-density lipoprotein and decrease in high-density lipoprotein. The PS-MPs caused glucose intolerance and increase in insulin. Moreover, the PS-MP exposure increased follicle stimulating hormone, estradiol, and testosterone. Serum level of interleukin-6 and nuclear factor kappa B (NF-κB) was elevated in animals treated with PS-MPs. The PS-MP exposed rats showed normal ovarian histology, but activated hepatic stellate cells and liver fibrosis. It is concluded that the sub-chronic exposure to PS-MPs resulted in metabolic and endocrine disruption in female rats through oxidative damage, hormonal imbalance, and chronic inflammation.
    MeSH term(s) Humans ; Female ; Rats ; Animals ; Polystyrenes/toxicity ; Polystyrenes/metabolism ; Microplastics/toxicity ; Plastics/toxicity ; Rats, Wistar ; Oxidative Stress
    Chemical Substances Polystyrenes ; Microplastics ; Plastics
    Language English
    Publishing date 2023-03-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-26565-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  6. Article: The Comparative Effect of Lactic Acid Fermentation and Germination on the Levels of Neurotoxin, Anti-Nutrients, and Nutritional Attributes of Sweet Blue Pea (

    Arshad, Nimra / Akhtar, Saeed / Ismail, Tariq / Saeed, Wisha / Qamar, Muhammad / Özogul, Fatih / Bartkiene, Elena / Rocha, João Miguel

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 15

    Abstract: Grass pea ( ...

    Abstract Grass pea (
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12152851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: UAVs-Enabled Maritime Communications

    Akhtar, Muhammad Waseem / Saeed, Nasir

    Opportunities and Challenges

    2022  

    Abstract: The next generation of wireless communication systems will integrate terrestrial and non-terrestrial networks targeting to cover the undercovered regions, especially connecting the marine activities. Unmanned aerial vehicles (UAVs) based connectivity ... ...

    Abstract The next generation of wireless communication systems will integrate terrestrial and non-terrestrial networks targeting to cover the undercovered regions, especially connecting the marine activities. Unmanned aerial vehicles (UAVs) based connectivity solutions offer significant advances to support the conventional terrestrial networks. However, the use of UAVs for maritime communication is still an unexplored area of research. Therefore, this paper highlights different aspects of UAV-based maritime communication, including the basic architecture, various channel characteristics, and use cases. The article, afterward, discusses several open research problems such as mobility management, trajectory optimization, interference management, and beamforming.

    Comment: 6 pages, 5 figures
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Publishing date 2022-06-07
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Impact of the first Gulf war on multiple sclerosis risk in Kuwait: a quasi-experimental study.

    Akhtar, Saeed / Al-Hashel, Jasem Y / Alroughani, Raed

    BMC neurology

    2023  Volume 23, Issue 1, Page(s) 259

    Abstract: Objective: It has been reasoned that stressful life events tend to alter immune function thereby increasing the susceptibility to autoimmune diseases including multiple sclerosis (MS). Using the database of Kuwait National MS Registry, this quasi- ... ...

    Abstract Objective: It has been reasoned that stressful life events tend to alter immune function thereby increasing the susceptibility to autoimmune diseases including multiple sclerosis (MS). Using the database of Kuwait National MS Registry, this quasi-experimental study assessed the impact of the first Gulf War (Iraqi invasion of Kuwait in 1990) on MS risk in Kuwait.
    Methods: MS incidence data from 1980 to 2019 were obtained from the Kuwait National MS Registry. Annual age-standardized incidence rates (ASIRs) (per 10
    Results: Estimated baseline annual ASIR (per 10
    Conclusions: This study suggests that the first Gulf War was not significantly associated with the increasing trend in MS risk at population level in Kuwait neither with any short-term change nor with secular trend. Future studies may consider confirming the role of conflict-related stress or other stressful life events in potential exacerbation of MS risk along with unraveling biologically plausible mechanistic pathways.
    MeSH term(s) Humans ; Child ; Kuwait/epidemiology ; Multiple Sclerosis/epidemiology ; Incidence ; Registries ; Gulf War
    Language English
    Publishing date 2023-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041347-6
    ISSN 1471-2377 ; 1471-2377
    ISSN (online) 1471-2377
    ISSN 1471-2377
    DOI 10.1186/s12883-023-03295-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A cross-sectional study on alcohol and contraception use among sexually active women of childbearing age: Implications for preventing alcohol-exposed pregnancies.

    Parackal, Sherly / Parackal, Mathew / Akhtar, Sumera Saeed

    Women's health (London, England)

    2023  Volume 19, Page(s) 17455057231161479

    Abstract: Background: A high proportion of unwanted or unplanned pregnancies may be alcohol-exposed due to contraception failure or non-use. Nevertheless, data on contraception and alcohol use in the context of the risk of alcohol-exposed pregnancies are sparse.!# ...

    Abstract Background: A high proportion of unwanted or unplanned pregnancies may be alcohol-exposed due to contraception failure or non-use. Nevertheless, data on contraception and alcohol use in the context of the risk of alcohol-exposed pregnancies are sparse.
    Objectives: To describe contraception use and alcohol consumption in sexually active non-pregnant women and investigate the factors associated with less effective contraception methods.
    Study design: A cross-sectional national survey of women aged 18-35 years.
    Methods: Data from non-pregnant women who were sexually active (
    Results: The majority of participants were younger (46%), of NZ European ethnicity (78%), not in a permanent relationship (54%), with some or completed tertiary education (79%), employed (81%) and not users of the community services card (82%). Twenty-five percent of women were smokers, 94% consumed alcohol, and 72% binged at least 'monthly or less'. Most women used the pill (56%), and 20% of drinking women were using a contraception method with a 10% or more annual failure rate after 1 year of use. Women who binged 'weekly or more often' had similar odds of using less effective contraception as women who 'never' binged (
    Conclusion: With 20% of women at risk of an alcohol-exposed pregnancy, public health measures to address alcohol consumption and the effective use of contraception are critical to reducing the risk for alcohol-exposed pregnancies in NZ.
    MeSH term(s) Pregnancy ; Female ; Humans ; Cross-Sectional Studies ; Contraception ; Pregnancy, Unplanned ; Ethnicity ; Ethanol ; Alcohol Drinking/epidemiology
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-03-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274503-8
    ISSN 1745-5065 ; 1745-5057
    ISSN (online) 1745-5065
    ISSN 1745-5057
    DOI 10.1177/17455057231161479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6629: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Book ; Online ; Thesis: Climate Change and Human Mobility

    Khan, Saeed Akhtar [Verfasser] / Sass, Oliver [Akademischer Betreuer]

    An Interdisciplinary Study in the Eastern Hindu Kush

    2024  

    Author's details Saeed Akhtar Khan ; Betreuer: Oliver Sass
    Keywords Geowissenschaften ; Earth Sciences
    Subject code sg550
    Language English
    Publisher Universität Bayreuth
    Publishing place Bayreuth
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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