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  1. Article ; Online: Myocardial performance index and cardiovascular diseases.

    Askin, Lutfu / Yuce, Elif İlkay / Tanriverdi, Okan

    Echocardiography (Mount Kisco, N.Y.)

    2023  Volume 40, Issue 7, Page(s) 720–725

    Abstract: The Myocardial Performance Index (MPI), also known as the Tei Index, is a measure of the overall performance of the heart that takes into account both systolic and diastolic function. It is a non-invasive echocardiographic index that provides information ...

    Abstract The Myocardial Performance Index (MPI), also known as the Tei Index, is a measure of the overall performance of the heart that takes into account both systolic and diastolic function. It is a non-invasive echocardiographic index that provides information about the efficiency of the heart's pumping action. The MPI is a useful tool for evaluating cardiac function in various clinical conditions, such as heart failure, myocardial infarction, and cardiomyopathy. A higher MPI value indicates poorer cardiac function, while a lower MPI value indicates better cardiac function. This review will give a summary of the relevant MPI literature, provide a methodology and technical aspects, and make research recommendations.
    MeSH term(s) Humans ; Cardiovascular Diseases/diagnostic imaging ; Echocardiography, Doppler/methods ; Myocardial Infarction ; Heart ; Heart Failure
    Language English
    Publishing date 2023-05-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 843645-9
    ISSN 1540-8175 ; 0742-2822
    ISSN (online) 1540-8175
    ISSN 0742-2822
    DOI 10.1111/echo.15628
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  2. Article ; Online: Evaluation of index of cardio-electrophysiological balance in patients with coronary slow flow.

    Askin, Lutfu / Tanrıverdi, Okan

    Acta cardiologica

    2021  Volume 77, Issue 4, Page(s) 337–341

    Abstract: Background: Coronary slow flow (CSF) is defined as the late progression of applied contrast through coronary arteries. The cardiac electrophysiological balance index (iCEB) reflects the balance between ventricular depolarisation and repolarisation and ... ...

    Abstract Background: Coronary slow flow (CSF) is defined as the late progression of applied contrast through coronary arteries. The cardiac electrophysiological balance index (iCEB) reflects the balance between ventricular depolarisation and repolarisation and provides more information about ventricular arrhythmogenesis (VA) than other electrocardiography (ECG) parameters (QT, corrected QT [QTc], etc.).
    Aim: We aimed to evaluate iCEB in patients with CSF.
    Methods: We divided the study population into two groups as CSF and control. The CSF group consisted of 100 patients (33 female, 67 male, mean age 52.2 ± 2.6), while the control group consisted of the same number of age and sex-matched patients (35 female, 65 male, mean age 51.7 ± 1.4). ECG parameters of the study population (QRS duration, QT, T wave peak-to-end (Tp-e) intervals, iCEB (QT/QRS), and iCEBc (heart rate QTc/QRS) rates were calculated and compared between CSF and control groups.
    Results: Intervals (QT and QTc intervals) and Tp-e/QTc ratio were greater in the CSF group compared with controls [422.1 ± 12.8 vs. 349.4 ± 14.3 bpm, respectively,
    Conclusions: ICEB and iCEBc were significantly increased in patients with CSF. This may suggest that CSF may predispose to malign arrhythmias.
    MeSH term(s) Action Potentials ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/etiology ; Electrocardiography ; Female ; Heart ; Heart Rate ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2021-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 390197-x
    ISSN 1784-973X ; 0001-5385
    ISSN (online) 1784-973X
    ISSN 0001-5385
    DOI 10.1080/00015385.2021.1945232
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  3. Article ; Online: Artificial Algorithms Outperform Traditional Models in Predicting Coronary Artery Disease.

    Askin, Lutfu / Tanrıverdi, Okan / Cetin, Mustafa

    Arquivos brasileiros de cardiologia

    2021  Volume 117, Issue 6, Page(s) 1071–1072

    Title translation Algoritmos Artificiais Superam os Modelos Tradicionais na Predição de Doença Arterial Coronariana.
    MeSH term(s) Algorithms ; Coronary Angiography ; Coronary Artery Disease/diagnosis ; Humans
    Language Portuguese
    Publishing date 2021-09-03
    Publishing country Brazil
    Document type Editorial ; Comment
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20210823
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  4. Article ; Online: Serum apelin levels and cardiovascular diseases.

    Askin, Lutfu / Askin, Husna Sengul / Tanrıverdi, Okan / Ozyildiz, Ali Gokhan / Duman, Hakan

    Northern clinics of Istanbul

    2022  Volume 9, Issue 3, Page(s) 290–294

    Abstract: Apelin is a G protein-linked receptor endogenous ligand, synthesized as a 77-amino acid pre-propeptide. Increased expression of apelin is present in many cardiovascular (CV) tissues, including cardiomyocytes. It is a peripheral vasodilator and one of the ...

    Abstract Apelin is a G protein-linked receptor endogenous ligand, synthesized as a 77-amino acid pre-propeptide. Increased expression of apelin is present in many cardiovascular (CV) tissues, including cardiomyocytes. It is a peripheral vasodilator and one of the most potent stimulants of ventricular contraction. Apelin may be a valuable therapeutic for both blood pressure regulation and myocardial performance. More information is needed for the CV pathophysiology of apelin. We will discuss the importance of apelin level in CV diseases in this review.
    Language English
    Publishing date 2022-05-11
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 3031921-3
    ISSN 2536-4553 ; 2148-4902
    ISSN (online) 2536-4553
    ISSN 2148-4902
    DOI 10.14744/nci.2021.33427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Resistin and Cardiovascular Disease: A Review of the Current Literature Regarding Clinical and Pathological Relationships.

    Askin, Lutfu / Abus, Sabri / Tanriverdi, Okan

    Current cardiology reviews

    2021  Volume 18, Issue 1, Page(s) e290721195114

    Abstract: Serum resistin, mainly secreted by the bone marrow, monocytes, and macrophages, contributes to many processes, including endothelial dysfunction, Vascular Smooth Muscle Cell (VSMC) proliferation, and atherothrombosis demonstrating effects on the ... ...

    Abstract Serum resistin, mainly secreted by the bone marrow, monocytes, and macrophages, contributes to many processes, including endothelial dysfunction, Vascular Smooth Muscle Cell (VSMC) proliferation, and atherothrombosis demonstrating effects on the development of hypertension and Coronary Artery Disease (CAD). Previously published clinical studies have shown that plasma resistin levels are significantly associated with cardiovascular disease risk factors and adverse clinical outcomes associated with the condition. Resistin is associated with vascular smooth muscle cell dysfunction in vitro, most plausibly due to its relationship with oxidative stress in advanced atherosclerosis whereas in vivo studies have shown resistin to be associated with intimal hyperplasia. We aimed to summarize the role of resistin on cardiovascular disease (CVD), as we could not find any review focused on the role of resistin on CVD.
    MeSH term(s) Atherosclerosis ; Cardiovascular Diseases/etiology ; Humans ; Macrophages/physiology ; Myocytes, Smooth Muscle/physiology ; Resistin/physiology
    Chemical Substances Resistin
    Language English
    Publishing date 2021-07-29
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 1875-6557
    ISSN (online) 1875-6557
    DOI 10.2174/1573403X17666210729101120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Effect of Coronavirus Disease 2019 on Cardiovascular Diseases.

    Askin, Lutfu / Tanrıverdi, Okan / Askin, Husna Sengul

    Arquivos brasileiros de cardiologia

    2020  Volume 114, Issue 5, Page(s) 817–822

    Abstract: Coronavirus disease 2019 (COVID-19) is a global pandemic affecting the world, seen in more than 1,300,000 patients. COVID-19 acts through the angiotensin-converting enzyme 2 (ACE2) receptor. Cardiovascular comorbidities are more common with COVID-19, and ...

    Title translation O Efeito da Doença de Coronavírus 2019 nas Doenças Cardiovasculares.
    Abstract Coronavirus disease 2019 (COVID-19) is a global pandemic affecting the world, seen in more than 1,300,000 patients. COVID-19 acts through the angiotensin-converting enzyme 2 (ACE2) receptor. Cardiovascular comorbidities are more common with COVID-19, and nearly 10% of cases develop myocarditis (22% of critical patients). Further research is needed to continue or discontinue ACE inhibitors and angiotensin receptor blockers, which are essential in hypertension and heart failure in COVID-19. Intensive research is promising for the treatment and prevention of COVID-19.
    MeSH term(s) Angiotensin Receptor Antagonists/metabolism ; Angiotensin-Converting Enzyme 2 ; Animals ; Antirheumatic Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Cardiovascular Diseases/enzymology ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/mortality ; China/epidemiology ; Chloroquine/therapeutic use ; Comorbidity ; Coronavirus Infections/drug therapy ; Coronavirus Infections/enzymology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Humans ; Hypertension/enzymology ; Hypertension/epidemiology ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/enzymology ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; SARS-CoV-2
    Chemical Substances Angiotensin Receptor Antagonists ; Antirheumatic Agents ; Antiviral Agents ; Chloroquine (886U3H6UFF) ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language Portuguese
    Publishing date 2020-05-29
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20200273
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  7. Article ; Online: O Efeito da Doença de Coronavírus 2019 nas Doenças Cardiovasculares

    Askin, Lutfu / Tanrıverdi, Okan / Askin, Husna Sengul

    Arquivos Brasileiros de Cardiologia v.114 n.5 2020

    2020  

    Abstract: Resumo A doença de coronavírus 2019 (COVID-19) é uma pandemia global afetando o mundo, estando presente em mais de 1.300.000 pacientes. O COVID-19 age pelo receptor da enzima conversora de angiotensina 2 (ECA2). As comorbidades cardiovasculares são mais ... ...

    Abstract Resumo A doença de coronavírus 2019 (COVID-19) é uma pandemia global afetando o mundo, estando presente em mais de 1.300.000 pacientes. O COVID-19 age pelo receptor da enzima conversora de angiotensina 2 (ECA2). As comorbidades cardiovasculares são mais frequentes com COVID-19, e cerca 10% de casos desenvolvem miocardite (22% de pacientes críticas). Mais pesquisas serão necessárias para continuar ou descontinuar inibidores de ECA e bloqueadores dos receptores da angiotensina, que são essenciais para hipertensão e insuficiência cardíaca em COVID-19. Pesquisa intensiva é promissora para o tratamento e a prevenção da COVID-19.
    Keywords Coronavirus ; COVID-19 ; Doenças Cardiovasculares/complicações ; Comorbidade ; Hipertensão ; Insuficiência Cardíaca ; Miocardite ; Síndrome Respiratória Aguda ; Pandemias ; Mortalidade ; Hospitalização ; Cuidados Críticos ; covid19
    Language Portuguese
    Publishing date 2020-05-01
    Publisher Sociedade Brasileira de Cardiologia - SBC
    Publishing country br
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Association of C-Reactive Protein to Albumin Ratio in Patients with Isolated Coronary Artery Ectasia.

    Sercelik, Alper / Tanrıverdi, Okan / Askin, Lutfu / Turkmen, Serdar

    Arquivos brasileiros de cardiologia

    2021  Volume 116, Issue 1, Page(s) 48–54

    Abstract: Background: Coronary artery ectasia (CAE) is defined as diffuse or localized dilatation of coronary artery lumen with a diameter of 1.5 to 2.0 times the adjacent normal coronary artery. The C-reactive protein to albumin ratio (CAR) is a useful ... ...

    Title translation A Associação da Relação Proteína C-Reativa/Albumina em Pacientes com Ectasia da Artéria Coronária Isolada.
    Abstract Background: Coronary artery ectasia (CAE) is defined as diffuse or localized dilatation of coronary artery lumen with a diameter of 1.5 to 2.0 times the adjacent normal coronary artery. The C-reactive protein to albumin ratio (CAR) is a useful inflammatory marker, which has been documented in coronary artery disease.
    Objective: To analyze the association of CAE and CAR.
    Methods: A case-control protocol was used in this study. We included 102 consecutive patients with isolated CAE without stenosis (56 men and 46 women; mean age 60.4 ± 8.8 years). The control subjects consisted of an equal number of sex and age matched patients with normal coronary arteries (55 men and 47 women; mean age 61.2 ± 9.1 years). Clinical features, laboratory findings, and medication use history were recorded. Student's t test, Mann-Whitney U test, chi-square test, and linear and logistic regression analysis were performed. A 2-sided p < 0.05 was statistically considered significant.
    Results: The CAR was increased in patients with CAE compared to the controls (32 and 16; p < 0.001). In addition, the CAR was found to be an independent predictor of CAE (OR = 2.202; 95% CI 1.184 - 5.365; p < 0.001).
    Conclusion: In the present study, we determined that CAR levels were significantly higher in the CAE group than in the control group, and the CAR was significantly correlated with CAE. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).
    MeSH term(s) Aged ; C-Reactive Protein ; Case-Control Studies ; Coronary Aneurysm ; Coronary Angiography ; Coronary Artery Disease ; Coronary Vessels/diagnostic imaging ; Dilatation, Pathologic ; Female ; Humans ; Male ; Middle Aged
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language Portuguese
    Publishing date 2021-01-04
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20190476
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  9. Article ; Online: New Method Improves the Evaluation of Subclinical Left Ventricular Dysfunction in Type 2 Diabetes Mellitus.

    Askin, Lutfu / Tanrıverdi, Okan / Tibilli, Hakan / Turkmen, Serdar

    Arquivos brasileiros de cardiologia

    2019  Volume 113, Issue 2, Page(s) 216–217

    MeSH term(s) Diabetes Mellitus, Type 2 ; Humans ; Ventricular Dysfunction, Left ; Ventricular Function, Left
    Language Portuguese
    Publishing date 2019-09-02
    Publishing country Brazil
    Document type Editorial ; Comment
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.5935/abc.20190164
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  10. Article ; Online: Clinical importance of high- sensitivity troponin T in patients without coronary artery disease.

    Askin, Lutfu / Tanriverdi, Okan / Turkmen, Serdar

    Northern clinics of Istanbul

    2020  Volume 7, Issue 3, Page(s) 305–310

    Abstract: Cardiac troponin is the preferred biomarker for the diagnosis of the acute coronary syndrome (ACS), but many other diseases can be identified with elevated troponin levels in the absence of ACS. The recent development of a high-sensitive cardiac troponin ...

    Abstract Cardiac troponin is the preferred biomarker for the diagnosis of the acute coronary syndrome (ACS), but many other diseases can be identified with elevated troponin levels in the absence of ACS. The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits the detection of very low levels of cTnT. The use of hs-cTnT assay has emerged as a tool for identifying high-risk individuals for primary preventive treatment and can detect subclinical injury in asymptomatic patients. Hs-cTnT analyses are generally related to ischemia in the literature. Thus, we made an evaluation of hs-cTnT analysis in non-coronary patients, which may contribute to the literature.
    Language English
    Publishing date 2020-04-09
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 3031921-3
    ISSN 2536-4553 ; 2148-4902
    ISSN (online) 2536-4553
    ISSN 2148-4902
    DOI 10.14744/nci.2019.71135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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