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  1. Article ; Online: Metabolic Bariatric surgery in People with Obesity aged ≥65 Years.

    Çalık Başaran, Nursel / Marcoviciu, Dana / Dicker, Dror

    European journal of internal medicine

    2024  

    Abstract: Obesity management guidelines recommend metabolic bariatric surgery for individuals with body mass index (BMI) ≥35 kg/ ... ...

    Abstract Obesity management guidelines recommend metabolic bariatric surgery for individuals with body mass index (BMI) ≥35 kg/m
    Language English
    Publishing date 2024-03-30
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2608: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Post metabolic bariatric surgery weight regain: the importance of GLP-1 levels.

    Çalık Başaran, Nursel / Dotan, Idit / Dicker, Dror

    International journal of obesity (2005)

    2024  

    Abstract: Weight regain and insufficient weight loss are essential problems after metabolic bariatric surgery (MBS) in people living with obesity. Changes in the level of glucagon-like peptide-1 (GLP-1) secreted from the gut after bariatric surgery are one of the ... ...

    Abstract Weight regain and insufficient weight loss are essential problems after metabolic bariatric surgery (MBS) in people living with obesity. Changes in the level of glucagon-like peptide-1 (GLP-1) secreted from the gut after bariatric surgery are one of the underlying mechanisms for successful initial weight loss. Studies and meta-analyses have revealed that postprandial GLP-1 levels increase after the Roux-en-Y gastric bypass and sleeve gastrectomy, but fasting GLP-1 levels do not increase significantly. Some observational studies have shown the relationship between higher postprandial GLP-1 levels and successful weight loss after bariatric surgery. There is growing evidence that GLP-1-receptor agonist (GLP-1-RA) use in patients who regained weight after bariatric surgery has resulted in significant weight loss. In this review, we aimed to summarize the changes in endogenous GLP-1 levels and their association with weight loss after MBS, describe the effects of GLP-1-RA use on weight loss after MBS, and emphasize metabolic adaptations in light of the recent literature. We hypothesized that maintaining higher basal-bolus GLP-1-RA levels may be a promising treatment choice in people with obesity who failed to lose weight after bariatric surgery.
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 752409-2
    ISSN 1476-5497 ; 0307-0565
    ISSN (online) 1476-5497
    ISSN 0307-0565
    DOI 10.1038/s41366-024-01461-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1325: Show issues Location:
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  3. Article ; Online: Association of Waist Circumference and Body Mass Index Deciles Ratio with All-Cause Mortality: Findings from the National Health and Nutrition Examination Survey.

    Reges, Orna / Test, Tsafnat / Dicker, Dror / Karpati, Tomas

    Nutrients

    2024  Volume 16, Issue 7

    Abstract: Given the importance and continued interest in finding a simple, accessible, and universal measure which reflects both general and abdominal adiposity, this study tested for an association of the ratio of WC decile to BMI decile (WC-d/BMI-d) with all- ... ...

    Abstract Given the importance and continued interest in finding a simple, accessible, and universal measure which reflects both general and abdominal adiposity, this study tested for an association of the ratio of WC decile to BMI decile (WC-d/BMI-d) with all-cause mortality. Individuals aged 18-79 years who had participated in the National Health and Nutrition Examination Survey (NHANES) during the years 2007 to 2018 were included in the analysis. WC and BMI deciles were defined separately for males and females, while WC-d/BMI-d was calculated for each individual. The association of WC-d/BMI-d with mortality was assessed using logistic models for the total study population, and then again after stratification by sex, ethnicity, morbidity level, and BMI categories. Positive associations between WC-d/BMI-d and mortality were demonstrated for the total study population (adjusted OR = 1.545, 95%CI: 1.369-1.722) and within different sub-groups, including the population with a normal BMI level (adjusted OR = 1.32, 95%CI: 1.13-1.50). WC-d/BMI-d increased with age, with ~40 years representing a critical time point when WC-d surpasses BMI-d, with a sharper incline for males as compared to females. WC-d/BMI-d was significantly associated with all-cause mortality amongst NHANES American adults; thus, measurements of WC and its integration with BMI in this metric should be considered in clinical practice.
    MeSH term(s) Adult ; Female ; Male ; Humans ; Body Mass Index ; Waist Circumference ; Nutrition Surveys ; Ethnicity ; Logistic Models
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16070961
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  4. Article ; Online: Obesity is a chronic progressive relapsing disease of particular interest for internal medicine.

    Sbraccia, Paolo / Dicker, Dror

    Internal and emergency medicine

    2022  Volume 18, Issue 1, Page(s) 1–5

    MeSH term(s) Humans ; Chronic Disease ; Disease Progression ; Internal Medicine ; Obesity/complications ; Obesity/epidemiology
    Language English
    Publishing date 2022-10-22
    Publishing country Italy
    Document type Editorial
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03129-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6673: Show issues Location:
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  5. Article: Can Consultation by a Clinical Pharmacist Prevent Morbidity and Mortality in Patients Undergoing Bariatric Surgery?

    Azran, Carmil / Dahan, Almog Eliyahu / Shimoni, Orly / Dicker, Dror / Hammerman, Ariel / Dahan, Arik

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: The purpose of this work was to investigate the effect of clinical pharmacist consultation on the long-term morbidity and mortality outcomes among patients undergoing bariatric surgery. In this retrospective cohort study, 165 bariatric patients at ... ...

    Abstract The purpose of this work was to investigate the effect of clinical pharmacist consultation on the long-term morbidity and mortality outcomes among patients undergoing bariatric surgery. In this retrospective cohort study, 165 bariatric patients at Herzliya Medical Center who were identified as complex cases and were consulted by a clinical pharmacist (2013-2019) were compared with a wider group of bariatric patients with chronic diseases who were recorded in the Israeli General Bariatric Registry during the same years. The primary outcomes were rates of surgical complications, re-hospitalizations, and death up to one year after surgery. The secondary outcome was the rate of re-hospitalizations in different time periods. The twelve (12)-month rate of re-hospitalization in the intervention group was 10.9% vs. 19.5% in the comparison group (
    Language English
    Publishing date 2024-01-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020310
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  6. Article: Clinical Insights and Management Recommendations for COVID-19 Patients Hospitalized in Internal Medicine Departments: Recommendations by the Corona Department Heads in Israel.

    Segal, Gad / Mevorach, Dror / Elis, Avishay / Dicker, Dror

    The Israel Medical Association journal : IMAJ

    2020  Volume 22, Issue 5, Page(s) 275–277

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/therapy ; Hospital Departments ; Hospitalization ; Humans ; Internal Medicine ; Israel ; Pandemics ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5470: Show issues Location:
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  7. Article ; Online: Towards an adiposity-related disease framework for the diagnosis and management of obesities.

    Perdomo, Carolina M / Avilés-Olmos, Icíar / Dicker, Dror / Frühbeck, Gema

    Reviews in endocrine & metabolic disorders

    2023  Volume 24, Issue 5, Page(s) 795–807

    Abstract: Obesity is a complex disease that relapses frequently and associates with multiple complications that comprise a worldwide health priority because of its rising prevalence and association with numerous complications, including metabolic disorders, ... ...

    Abstract Obesity is a complex disease that relapses frequently and associates with multiple complications that comprise a worldwide health priority because of its rising prevalence and association with numerous complications, including metabolic disorders, mechanic pathologies, and cancer, among others. Noteworthy, excess adiposity is accompanied by chronic inflammation, oxidative stress, insulin resistance, and subsequent organ dysfunction. This dysfunctional adipose tissue is initially stored in the visceral depot, overflowing subsequently to produce lipotoxicity in ectopic depots like liver, heart, muscle, and pancreas, among others. People living with obesity need a diagnostic approach that considers an exhaustive pathophysiology and complications assessment. Thus, it is essential to warrant a holistic diagnosis and management that guarantees an adequate health status, and quality of life. The present review summarizes the different complications associated with obesity, at the same time, we aim to fostering a novel framework that enhances a patient-centered approach to obesity management in the precision medicine era.
    MeSH term(s) Humans ; Adiposity ; Quality of Life ; Obesity/diagnosis ; Obesity/therapy ; Obesity/complications ; Adipose Tissue/metabolism ; Inflammation/metabolism ; Insulin Resistance/physiology
    Language English
    Publishing date 2023-05-10
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-023-09797-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6069: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Clinical Insights and Management Recommendations for COVID-19 Patients Hospitalized in Internal Medicine Departments: Recommendations by the Corona Department Heads in Israel

    Segal, Gad / Mevorach, Dror / Elis, Avishay / Dicker, Dror

    Isr Med Assoc J

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32378816
    Database COVID19

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  9. Article ; Online: Do we know when to end isolation of persons affected with COVID-19?

    Dicker, Dror / Kournos, Tatiana / Marcoviciu, Dana / Golan, Rachel

    European journal of internal medicine

    2020  Volume 77, Page(s) 144–146

    MeSH term(s) Adolescent ; Adult ; Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Pandemics/prevention & control ; Patient Isolation ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Sex Factors ; Symptom Assessment ; Time Factors ; Viral Load ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-05-03
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.04.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2608: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Treatment of COVID-19 Patients Post-Bariatric Surgery: Issues for Consideration.

    Azran, Carmil / Porat, Daniel / Dahan, Arik / Dicker, Dror

    Journal of clinical medicine

    2020  Volume 9, Issue 9

    Abstract: As COVID-19 has been expanding rapidly around the world, the types of patients and their backgrounds vary. The substantially altered GI anatomy/physiology after bariatric surgery presents new challenges to the field of oral drug therapy. In this report ... ...

    Abstract As COVID-19 has been expanding rapidly around the world, the types of patients and their backgrounds vary. The substantially altered GI anatomy/physiology after bariatric surgery presents new challenges to the field of oral drug therapy. In this report we highlight issues for consideration when treating COVID-19 patients who previously underwent bariatric surgery and provide practical tools to allow optimal care of these patients. Post-bariatric absorption/pharmacokinetic changes may warrant dose adjustment, as well as the use of liquid oral dosage forms or parenteral routes of administration, if available. Realizing the potentially altered pharmacokinetics of various drugs after bariatric surgery is essential for providing optimal pharmacological therapy and overall patient care.
    Keywords covid19
    Language English
    Publishing date 2020-08-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm9092827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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