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  1. Article ; Online: Initial Antithrombotic Therapy After Percutaneous Left Atrial Appendage Occlusion: Shifting Approaches to a Moving Target.

    Halperin, Jonathan L / Rothman, Kenneth J

    Journal of the American College of Cardiology

    2023  Volume 82, Issue 18, Page(s) 1774–1776

    MeSH term(s) Humans ; Fibrinolytic Agents/therapeutic use ; Atrial Appendage/surgery ; Vascular Diseases ; Atrial Fibrillation/complications ; Atrial Fibrillation/surgery ; Stroke/etiology ; Stroke/prevention & control ; Stroke/drug therapy ; Treatment Outcome ; Anticoagulants
    Chemical Substances Fibrinolytic Agents ; Anticoagulants
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.08.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: No conflict of interest in data monitoring.

    Halperin, Jonathan L

    Science (New York, N.Y.)

    2018  Volume 362, Issue 6419, Page(s) 1123

    Language English
    Publishing date 2018-12-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.aau9738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Low-Dose Anticoagulation for Atrial Fibrillation: When Is a Floor a Trap Door?

    Halperin, Jonathan L / Rashed, Eman R

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 9, Page(s) 1208–1210

    MeSH term(s) Anticoagulants ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Blood Coagulation ; Humans ; Warfarin
    Chemical Substances Anticoagulants ; Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2021-03-04
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stability of Vancomycin and Ceftazidime With Prolonged Storage at -20°C.

    Halperin, Scott J / Greenblatt, David J / Prenner, Jonathan L / Fine, Howard F

    Ophthalmic surgery, lasers & imaging retina

    2023  Volume 54, Issue 5, Page(s) 281–283

    Abstract: Background and objective: Vancomycin and ceftazidime are commonly used intravitreal antibiotics for suspected bacterial endophthalmitis. Many retina surgical practices prepare aliquoted individual doses in syringes that are then stored frozen for future ...

    Abstract Background and objective: Vancomycin and ceftazidime are commonly used intravitreal antibiotics for suspected bacterial endophthalmitis. Many retina surgical practices prepare aliquoted individual doses in syringes that are then stored frozen for future use, but this practice has not been well studied. This investigation aims to examine the stability of frozen vancomycin and ceftazidime.
    Materials and methods: Samples of drugs were reconstituted monthly and placed in a -20°C freezer. At the end of 3 months and again at 6 months, a newly reconstituted drug constant was created and compared to a newly created reference sample. The frozen samples were compared to a freshly produced drug solution. Using high-performance liquid chromatography (HPLC), the peak heights were compared to evaluate stability.
    Results: The vancomycin reference sample was 100 ± 1.67%. Values over time were 97.4 ± 0.75%, 98.8 ± 0.44%, 102.1 ± 0.4%, 100.5 ± 0.12%, 101.8 ± 0.12, 101.5 ± 0.11, and 100.6 ± 1.87 for 1, 2, 3(A), 3(B), 4, 5, and 6 months, respectively. The ceftazidime reference sample was 100 ± 1.8%. Values over time were 100.7 ± 1.78%, 100.0 ± 1%, 102.3 ± 1.55%, 117.5 ± 11.6%, 112.8 ± 1.64%, 123 ± 2.8%, and 117 ± 2.5% for 1, 2, 3(A), 3(B), 4, 5, and 6 months, respectively.
    Conclusion: Both vancomycin and ceftazidime were stable over 6 months under frozen conditions at -20°C.
    MeSH term(s) Humans ; Ceftazidime/chemistry ; Vancomycin ; Anti-Bacterial Agents ; Eye Infections, Bacterial/microbiology ; Endophthalmitis/microbiology
    Chemical Substances Ceftazidime (9M416Z9QNR) ; Vancomycin (6Q205EH1VU) ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701167-7
    ISSN 2325-8179 ; 2325-8160
    ISSN (online) 2325-8179
    ISSN 2325-8160
    DOI 10.3928/23258160-20230310-01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Preventing Myocardial Infarction in Patients With Atrial Fibrillation: Another Piece of the Puzzle.

    Halperin, Jonathan L

    Journal of the American College of Cardiology

    2017  Volume 69, Issue 24, Page(s) 2910–2912

    MeSH term(s) Atrial Fibrillation ; Fibrinolytic Agents ; Humans ; Myocardial Infarction ; Warfarin
    Chemical Substances Fibrinolytic Agents ; Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2017-03-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2017.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Association Between Stable Coronary Artery Disease and Hospital Readmissions Following Catheter Ablation for Atrial Fibrillation.

    Satish, Mohan / Walters, Ryan W / Alla, Venkata M / Halperin, Jonathan L

    Mayo Clinic proceedings

    2023  Volume 98, Issue 6, Page(s) 892–902

    Abstract: Objective: To evaluate the association of stable coronary artery disease (CAD) with readmission following hospitalization for catheter ablation (CA) for atrial fibrillation (AF).: Patients and methods: Using the Nationwide Readmissions Database, we ... ...

    Abstract Objective: To evaluate the association of stable coronary artery disease (CAD) with readmission following hospitalization for catheter ablation (CA) for atrial fibrillation (AF).
    Patients and methods: Using the Nationwide Readmissions Database, we identified all hospitalizations from the last quarter of 2015 through 2019 with a Medicare Severity-Diagnosis Related Group designation for a percutaneous intracardiac procedure, a procedure code for CA, and a primary discharge diagnosis of AF. Cases of acute coronary syndrome (ACS) at index hospitalization were excluded to define stable CAD. The primary outcome was all-cause 90-day hospital readmission; secondary end points included readmissions for AF, repeated CA, ACS, and heart failure (HF).
    Results: Among 28,466 hospitalizations for CA for AF identified, 3171 (11.1%) involved patients with stable CAD. No hospitalizations included patients with HF diagnosis codes. The incidence of 90-day all-cause readmission was higher in patients with stable CAD (18.4% [400 of 2172] vs 14.4% [2549 of 17,667]; P=.006), as was the incidence of subsequent hospitalization with ACS (5.3% [21] vs 1.1% [28]; P<.001) or HF (17.0% [68] vs 10.2% [260]; P=.007). The incidence of readmission within 90 days with recurrent AF did not differ for those with or without stable CAD (21.9% [88] vs 26.5% [675]; P=.217). Pooled analysis of 90-day HF readmissions revealed a higher incidence among older patients, those with chronic kidney or pulmonary disease, and those with persistent and chronic AF subtypes.
    Conclusion: Results of this large-scale analysis suggest that among patients hospitalized for CA for AF, stable CAD is associated with hospital readmissions within 90 days, including admissions for ACS and decompensated HF.
    MeSH term(s) Humans ; Aged ; United States/epidemiology ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/surgery ; Atrial Fibrillation/diagnosis ; Patient Readmission ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/surgery ; Coronary Artery Disease/complications ; Risk Factors ; Medicare ; Neoplasm Recurrence, Local/surgery ; Heart Failure ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Retrospective Studies
    Language English
    Publishing date 2023-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antithrombotic Therapy to Reduce Mortality in Patients With Atherosclerosis: 2 Pathways to a Single Goal.

    Halperin, Jonathan L / Chen, Huazhen / Olin, Jeffrey W

    Journal of the American College of Cardiology

    2021  Volume 78, Issue 1, Page(s) 24–26

    MeSH term(s) Aspirin ; Atherosclerosis/drug therapy ; Fibrinolytic Agents/therapeutic use ; Goals ; Humans ; Rivaroxaban
    Chemical Substances Fibrinolytic Agents ; Rivaroxaban (9NDF7JZ4M3) ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-07-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Taking TASC to TASK: Evolving from nomenclature to guidelines.

    Halperin, Jonathan L

    Vascular medicine (London, England)

    2015  Volume 20, Issue 5, Page(s) 463–464

    MeSH term(s) Animals ; Humans ; Practice Guidelines as Topic ; Vascular Surgical Procedures/standards ; World Health Organization
    Language English
    Publishing date 2015-10
    Publishing country England
    Document type Editorial
    ZDB-ID 1311628-9
    ISSN 1477-0377 ; 1358-863X
    ISSN (online) 1477-0377
    ISSN 1358-863X
    DOI 10.1177/1358863X15598022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Response: “Actually, it’s more of a guideline than a rule”.

    Halperin, Jonathan L

    Journal of the American College of Cardiology

    2015  Volume 65, Issue 4, Page(s) 400

    MeSH term(s) American Heart Association/organization & administration ; Cardiology/organization & administration ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Coronary Artery Disease/prevention & control ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Hypercholesterolemia/drug therapy
    Chemical Substances Cholesterol, HDL ; Cholesterol, LDL ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2015-02-03
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: US Preventive Services Task Force recommendation statement regarding screening for peripheral artery disease with the ankle-brachial index: déjà vu all over again.

    Olin, Jeffrey W / Halperin, Jonathan L

    Lancet (London, England)

    2018  Volume 392, Issue 10153, Page(s) 1160–1162

    MeSH term(s) Ankle Brachial Index ; Asymptomatic Diseases ; Female ; Humans ; Male ; Mass Screening/methods ; Peripheral Arterial Disease/diagnosis ; Practice Guidelines as Topic ; Risk Factors
    Language English
    Publishing date 2018-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(18)31650-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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