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Article ; Online: Comparison of automated and manual control methods in minimal flow anesthesia.

Şerefoğlu, Rezan / Kocayiğit, Havva / Palabıyık, Onur / Tuna, Ayça Taş

Journal of clinical monitoring and computing

2024

Abstract: Purpose: New-generation anesthesia machines administer inhalation anesthetics and automatically control the fresh gas flow (FGF) rate. This study compared the administration of minimal flow anesthesia (MFA) using the automatically controlled anesthesia ( ...

Abstract	Purpose: New-generation anesthesia machines administer inhalation anesthetics and automatically control the fresh gas flow (FGF) rate. This study compared the administration of minimal flow anesthesia (MFA) using the automatically controlled anesthesia (ACA) module of the Mindray A9 (Shenzhen, China) anesthesia machine versus manual control by an anesthesiologist. Methods: We randomly divided 76 patients undergoing gynecological surgery into an ACA group (Group ACA) and a manually controlled anesthesia group (Group MCA). In Group MCA, induction was performed with a mixture of 40-60% O Results: The two groups showed no statistically significant differences in depth of anesthesia or AA consumption (Group ACA: 19.1 ± 4.9 ml; Group MCA: 17.2 ± 4.5; p-value = 0.076). The ACA mode achieved the MAC target of 1 significantly faster (Group ACA: 218 ± 51 s; Group MCA: 314 ± 169 s). The number of vaporizer adjustments was 15 in the ACA group and 217 in the MCA group. Conclusion: The ACA mode was more advantageous than the MCA mode, reaching target AA concentrations faster and requiring fewer adjustments to achieve a constant depth of anesthesia.
Language	English
Publishing date	2024-04-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1418733-4
ISSN	1573-2614 ; 1387-1307 ; 0748-1977
ISSN (online)	1573-2614
ISSN	1387-1307 ; 0748-1977
DOI	10.1007/s10877-024-01163-0
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Article ; Online: Percutaneous dilatational tracheostomy: evaluation of YouTube videos.

Kocayiğit, Havva / Bal, Nevcihan Şahutoğlu

Der Anaesthesist

2022

Abstract: Background and objective: In today's rapidly changing world, the technology of social media is widely used for educational purposes. Our aim in this study was to investigate the accuracy and efficacy of video presentations of percutaneous dilatational ... ...

Title translation	Perkutane Dilatationstracheostomie: Bewertung von YouTube-Videos.
Abstract	Background and objective: In today's rapidly changing world, the technology of social media is widely used for educational purposes. Our aim in this study was to investigate the accuracy and efficacy of video presentations of percutaneous dilatational tracheostomy procedures available on the international video sharing website YouTube. Methods: On 1 December 2020, the terms "percutaneous dilatational tracheostomy" and "percutaneous tracheostomy" were entered into the search feature of YouTube ( www.youtube.com ). The evaluation was made in three categories; general information about percutaneous tracheostomy, performing percutaneous tracheostomy steps and demographic features of videos. Results: The median number of viewings of the videos on the date our data were collected was 1342 (IQR, 237-8052), and the most watched video had been viewed 325,170 times. Surgical site cleaning was explained in 46 (65.7%) videos and incision site detection in 55 (78.6%) videos. Needle aspiration into the trachea, insertion of the Seldinger guidewire, dilatation, and tracheal tube placement were covered in all videos (70; 100%). Confirmation of the location of the tracheal tube with end tidal capnography, the last step of the procedure, is available in 34 videos (48.6%). Conclusion: The use of inexpensive or freely available teaching materials is possible but should always be checked before use with respect to the completeness and correctness of the content conveyed. The unreflected adoption of such content can lead to serious treatment errors.
Language	English
Publishing date	2022-05-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	260-4
ISSN	1432-055X ; 0003-2417
ISSN (online)	1432-055X
ISSN	0003-2417
DOI	10.1007/s00101-022-01122-x
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Article ; Online: Increased Cardio-ankle Vascular Index Values in Migraine Patients With Aura.

Can, Yusuf / Uçaroğlu Can, Nimet / Akçay, Çağla / Ulaş, Sena Boncuk / Kocayiğit, Ibrahim / Kocayiğit, Havva / Ağaç, Mustafa Tarık

Angiology

2024 , Page(s) 33197241228043

Abstract: Patients with migraine with aura are at an increased risk of cardiovascular disease. There are limited data on arterial stiffness in migraine patients with aura. The present study evaluated arterial stiffness in these patients using the cardio-ankle ... ...

Abstract	Patients with migraine with aura are at an increased risk of cardiovascular disease. There are limited data on arterial stiffness in migraine patients with aura. The present study evaluated arterial stiffness in these patients using the cardio-ankle vascular index (CAVI). This prospective study included 50 patients with migraine with aura (43 female, mean age 38.9 ± 9.9 years). The patient group was matched for age and gender with 50 healthy individuals with no history of migraine (43 female, mean age 39.3 ± 10.3 years). All patients and control subjects underwent a comprehensive clinical evaluation by an experienced neurologist and were interviewed about their headache histories. There was no significant difference in baseline demographic characteristics and echocardiographic parameters between migraine with aura patients and the control group. Both right and left CAVI values were significantly higher in the patients with migraine with aura (6.5 ± 1.2 vs 6.1 ± 0.7,
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	80040-5
ISSN	1940-1574 ; 0003-3197
ISSN (online)	1940-1574
ISSN	0003-3197
DOI	10.1177/00033197241228043
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Article: Comparison of cooled and conventional radiofrequency applications for the treatment of osteoarthritic knee pain.

Kocayiğit, Havva / Beyaz, Serbülent Gökhan

Journal of anaesthesiology, clinical pharmacology

2021 Volume 37, Issue 3, Page(s) 464–468

Abstract: Background and aims: Osteoarthritis is a progressive degenerative joint disease that affects the joint cartilage and surrounding tissues. It has been determined that osteoarthritis-induced knee pain is the most common cause of physical disability in the ...

Abstract	Background and aims: Osteoarthritis is a progressive degenerative joint disease that affects the joint cartilage and surrounding tissues. It has been determined that osteoarthritis-induced knee pain is the most common cause of physical disability in the elderly. Material and methods: In this study, the genicular nerve RF treatments of patients with osteoarthritic knee pain conducted at the Sakarya University Training and Research Hospital in the algology clinic of the Anaesthesiology and Reanimation Department between January 2016 and December 2016 were retrospectively examined. The preoperative and postoperative 2 Results: When the data of the patients were evaluated statistically, the preoperative VAS and WOMAC scores were found significantly decreased compared with the postoperative 2 Conclusion: We found that both cooled and conventional RF techniques in genicular nerve ablation are similarly effective in reducing pain in patients with osteoarthritis-induced knee pain and improving patients' physical functions. The complication rates are very low and there was no superiority to each other.
Language	English
Publishing date	2021-10-12
Publishing country	India
Document type	Journal Article
ZDB-ID	1401760-x
ISSN	0970-9185
ISSN	0970-9185
DOI	10.4103/joacp.JOACP_126_19
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Article ; Online: Ongoing Effects of SARS-CoV-2 Infection on Arterial Stiffness in Healthy Adults.

Can, Yusuf / Kocayigit, Ibrahim / Kocayiğit, Havva / Sarıbıyık Çakmak, Betul / Şahinöz, Mustafa / Akdemir, Ramazan

Angiology

2023 Volume 75, Issue 2, Page(s) 116–121

Abstract: There are limited data on the arterial stiffness changes after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The present study evaluated the changes in arterial stiffness in completely healthy patients who had a SARS-CoV-2 ... ...

Abstract	There are limited data on the arterial stiffness changes after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The present study evaluated the changes in arterial stiffness in completely healthy patients who had a SARS-CoV-2 infection using the cardio-ankle vascular index (CAVI). The study included 70 patients with SARS-CoV-2 infection between December 2020 and June 2021. A cardiac evaluation was carried out, including chest X-ray, electrocardiography (ECG), and echocardiography in all patients. Within the 1st month and 7th month CAVI was measured. Mean age was 37.8 ± 10.0 years, and 41/70 were female. Mean height was 168.6 ± 9.5 cm, mean weight 73.2 ± 15.1 kg, and mean body mass index (BMI) of the group was 25.6 ± 4.2, respectively. CAVI results from the right arm were 6.45 ± .95 at 1-month follow-up and 6.68 ± 1.05 at 7 months follow-up (P = .016) and from the left arm were 6.43 ± 1.0 at 1-month follow-up, 6.70 ± 1.05 at 7-month follow-up (P = .005). Our results showed an ongoing injury in the arterial system after healthy SARS-COV-2 patients during 7 months, as represented by CAVI measurements.
MeSH term(s)	Adult ; Humans ; Female ; Middle Aged ; Male ; Vascular Stiffness ; Ankle/blood supply ; COVID-19 ; SARS-CoV-2 ; Heart
Language	English
Publishing date	2023-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	80040-5
ISSN	1940-1574 ; 0003-3197
ISSN (online)	1940-1574
ISSN	0003-3197
DOI	10.1177/00033197231183227
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Article ; Online: Comparison of Ultrasound-Guided Popliteal Sciatic Block Properties in Diabetic and Nondiabetic Patients.

Kocayigit, Havva / Şahin, Fatih / Erkin, Alper / Erdem, Ali Fuat

Journal of the American Podiatric Medical Association

2023 Volume 113, Issue 3

Abstract: Background: We aim to share our popliteal sciatic nerve block (PSB) experience, which we applied to diabetic and nondiabetic patients in the operating room of our hospital.: Methods: The patients who underwent PSB for foot and ankle surgery between ... ...

Abstract	Background: We aim to share our popliteal sciatic nerve block (PSB) experience, which we applied to diabetic and nondiabetic patients in the operating room of our hospital. Methods: The patients who underwent PSB for foot and ankle surgery between October 1, 2021, and December 31, 2021, in Sakarya University Training and Research Hospital were evaluated retrospectively. All nerve blocks were administered by a single anesthesiologist. Demographic data of the patients and the duration of the operation, the type of operation, the time of application of the nerve block, whether it was single or bifurcation block, and the onset times of motor and sensory block were also recorded in the perioperative period. Results: It was determined that PSB was applied to 49 patients over a 3-month period. The mean age of the patients was 61.33 ± 14.03 years, and 12 patients (24.5%) were women. The reason why the patients were operated on was amputation in 21 (42.9%) and wound debridement in 27 (55.1%). There were 37 patients in the diabetic group and 12 patients in the nondiabetic group. There was no significant difference between the two groups in terms of demographic data and operation characteristics, but it was observed that there was a significant difference in both sensory and motor block formation times between the two groups (P < .001). Conclusions: In conclusion, we think that popliteal sciatic nerve block is easy to apply, the complication rate is low, and it is a suitable anesthesia method for patients who will undergo day surgery for foot ulcer.
MeSH term(s)	Humans ; Female ; Middle Aged ; Aged ; Male ; Sciatic Nerve/diagnostic imaging ; Retrospective Studies ; Ultrasonography ; Nerve Block/methods ; Ultrasonography, Interventional/methods ; Diabetes Mellitus
Language	English
Publishing date	2023-07-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	632622-5
ISSN	1930-8264 ; 0003-0538 ; 8750-7315
ISSN (online)	1930-8264
ISSN	0003-0538 ; 8750-7315
DOI	10.7547/22-028
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Article ; Online: Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study.

Eman, Ali / Balaban, Onur / Kocayiğit, Havva / Süner, Kezban Özmen / Cırdı, Y / Erdem, Ali Fuat

Journal of Korean medical science

2021 Volume 36, Issue 44, Page(s) e309

Abstract: Background: We assessed maternal and neonatal outcomes of critically ill pregnant and puerperal patients in the clinical course of coronavirus disease 2019 (COVID-19).: Methods: Records of pregnant and puerperal women with polymerase chain reaction ... ...

Abstract	Background: We assessed maternal and neonatal outcomes of critically ill pregnant and puerperal patients in the clinical course of coronavirus disease 2019 (COVID-19). Methods: Records of pregnant and puerperal women with polymerase chain reaction positive COVID-19 virus who were admitted to our intensive care unit (ICU) from March 2020 to August 2021 were investigated. Demographic, clinical and laboratory data, pharmacotherapy, and neonatal outcomes were analyzed. These outcomes were compared between patients that were discharged from ICU and patients who died in ICU. Results: Nineteen women were included in this study. Additional oxygen was required in all cases (100%). Eight patients (42%) were intubated and mechanically ventilated. All patients that were mechanically ventilated have died. Increased levels of C-reactive protein (CRP) was seen in all patients (100%). D-dimer values increased in 15 patients (78.9%); interleukin-6 (IL-6) increased in 16 cases (84.2%). Sixteen patients used antiviral drugs. Eleven patients were discharged from the ICU and eight patients have died due to complications of COVID-19 showing an ICU mortality rate of 42.1%. Mean number of hospitalized days in ICU was significantly lower in patients that were discharged ( Conclusion: High mortality rate was detected among critically ill pregnant/parturient patients followed in the ICU. Main predictors of mortality were the need of invasive mechanical ventilation and higher number of days hospitalized in ICU. Rate of C/S operations and preterm delivery were high. Pleasingly, the rate of neonatal death was low and no neonatal COVID-19 occurred.
MeSH term(s)	Adult ; Antiviral Agents/therapeutic use ; COVID-19/blood ; COVID-19/diagnostic imaging ; COVID-19/mortality ; COVID-19/therapy ; Cesarean Section ; Combined Modality Therapy ; Critical Illness/mortality ; Delivery, Obstetric/statistics & numerical data ; Female ; Hospital Mortality ; Humans ; Infant, Newborn ; Intensive Care Units/statistics & numerical data ; Length of Stay/statistics & numerical data ; Lung/diagnostic imaging ; Oxygen Inhalation Therapy ; Pregnancy ; Pregnancy Complications, Infectious/mortality ; Pregnancy Outcome ; Puerperal Disorders/mortality ; Respiration, Artificial ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; Young Adult
Chemical Substances	Antiviral Agents
Language	English
Publishing date	2021-11-15
Publishing country	Korea (South)
Document type	Comparative Study ; Journal Article ; Observational Study
ZDB-ID	639262-3
ISSN	1598-6357 ; 1011-8934
ISSN (online)	1598-6357
ISSN	1011-8934
DOI	10.3346/jkms.2021.36.e309
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Article ; Online: Impact of antihypertensive agents on clinical course and in-hospital mortality: analysis of 169 hypertensive patients hospitalized for COVID-19.

Kocayigit, Ibrahim / Kocayigit, Havva / Yaylaci, Selcuk / Can, Yusuf / Erdem, Ali Fuat / Karabay, Oguz

Revista da Associacao Medica Brasileira (1992)

2020 Volume 66Suppl 2, Issue Suppl 2, Page(s) 71–76

Abstract: Objective: Coronavirus disease 2019 (COVID-19) is an emerging health threat caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Previous studies have noted hypertension is associated with increased mortality ...

Abstract	Objective: Coronavirus disease 2019 (COVID-19) is an emerging health threat caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Previous studies have noted hypertension is associated with increased mortality due to COVID-19; however, it is not clear whether the increased risk is due to hypertension itself or antihypertensive agents. We aimed to evaluate the impact of antihypertensive agents on the clinical outcomes of hypertensive patients with COVID-19. Methods: Our study included 169 consecutive hypertensive patients hospitalized due to COVID-19 between March 20 and April 10, 2020. The demographic characteristics, clinical data, and type of antihypertensive agents being used were reviewed. Results: The mean age of patients was 65.8±11.7 years.30 patients(17.7%) died during hospitalization. A total of 142 patients(84%) were using angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs), 91 (53.8%) were using diuretics, 69 (40.8%) were using calcium channel blockers (CCBs), 66 (39.1%) were using beta-blockers, 12 (7.1%) were using alpha-blockers, and 5 (2.9%) were using mineralocorticoid receptor antagonists (MRAs). There was no significant difference between survivors and non-survivors based on the type of antihypertensive agents being used. Binary logistic regression analysis showed that the type of the antihypertensive agent being used had no effect on mortality [OR=0.527 (0.130-2.138), p=0.370 for ACEIs/ARBs; OR=0.731 (0.296-1.808), p=0.498 for CCBs; OR=0.673 (0.254-1.782), p=0.425 for diuretics; OR=1.846 (0.688-4.950), p=0.223 for beta-blockers; OR=0.389 (0.089-1.695), p=0.208 for alpha-blockers; and OR=1.372 (0.107-17.639), p=0.808 for MRAs]. Conclusion: The type of antihypertensive agent being used had no effect on the clinical course and mortality in hypertensive patients with COVID-19. The use of these agents should be maintained for the treatment of hypertension during hospitalization.
MeSH term(s)	Aged ; Aged, 80 and over ; Antihypertensive Agents/adverse effects ; Antihypertensive Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Female ; Hospital Mortality ; Humans ; Hypertension/drug therapy ; Hypertension/mortality ; Inpatients/statistics & numerical data ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/mortality ; SARS-CoV-2
Chemical Substances	Antihypertensive Agents
Keywords	covid19
Language	English
Publishing date	2020-09-21
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	731969-1
ISSN	1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
ISSN (online)	1806-9282
ISSN	0104-4230 ; 0004-5241 ; 0102-843X
DOI	10.1590/1806-9282.66.S2.71
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Article ; Online: Serum calprotectin as a novel biomarker for severity of COVID-19 disease.

Kaya, Tezcan / Yaylacı, Selçuk / Nalbant, Ahmet / Yıldırım, İlhan / Kocayiğit, Havva / Çokluk, Erdem / Şekeroğlu, Mehmet Ramazan / Köroğlu, Mehmet / Güçlü, Ertuğrul

Irish journal of medical science

2021 Volume 191, Issue 1, Page(s) 59–64

Abstract: Background: Some biomarkers have been reported to be related to the prognosis of the coronavirus disease 2019 (COVID-19). There are sparse data regarding the prognostic value of serum calprotectin in COVID-19 patients.: Aims: This study aimed to ... ...

Abstract	Background: Some biomarkers have been reported to be related to the prognosis of the coronavirus disease 2019 (COVID-19). There are sparse data regarding the prognostic value of serum calprotectin in COVID-19 patients. Aims: This study aimed to investigate the relationship between serum calprotectin level and clinical severity of COVID-19 disease in hospitalized patients. Methods: This retrospective cross-sectional cohort study included 80 consecutive hospitalized patients with confirmed diagnosis of COVID-19. The study population was divided into two groups as patients hospitalized in the intensive care unit (ICU) and patients hospitalized but not in the ICU. The serum calprotectin levels, other laboratory, and clinical parameters were compared between groups. Results: The mean age of the patients was 66.5 ± 15.7 years. Of the patients, 42 were in the ICU and 38 were not. Serum calprotectin level and acute-phase reactants such as C-reactive protein, procalcitonin, ferritin, fibrinogen, and white blood cell were significantly higher in ICU patients than in non-ICU patients. ROC curve analysis identified that serum calprotectin level was a predictor for ICU requirement with an area under the curve of 0.641 (p = 0.031). Logistic regression analysis revealed that serum calprotectin was a significant determinant for whether or not patient required the ICU. Conclusions: These findings demonstrate that serum calprotectin level seems to be a useful biomarker that can predict the severity of COVID-19 disease. Serum calprotectin is a significant predictor of ICU requirement in patients with COVID-19.
MeSH term(s)	Aged ; Aged, 80 and over ; Biomarkers/blood ; COVID-19/diagnosis ; Cross-Sectional Studies ; Humans ; Intensive Care Units ; Leukocyte L1 Antigen Complex/blood ; Middle Aged ; Patient Acuity ; Prognosis ; Retrospective Studies
Chemical Substances	Biomarkers ; Leukocyte L1 Antigen Complex
Language	English
Publishing date	2021-02-27
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-021-02565-8
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Article ; Online: Evaluation of Increased Intracranial Pressure with the Optic Nerve Sheath Diameter by Ultrasound in Epiduroscopic Neural Laser Discectomy Procedures.

Beyaz, Serbulent Gokhan / Kaya, Burak / Ulgen, Ali Metin / Sahin, Fatih / Kocayigit, Havva / Issi, Zeynep Tuncer

Pain physician

2021 Volume 24, Issue 5, Page(s) E595–E600

Abstract: Background: In order to clarify the camera image and open the adhesions mechanically during epiduroscopy, saline is injected continuously in the epidural area. As a result, an increase in intracranial pressure is to be expected in theory. Increased ... ...

Abstract	Background: In order to clarify the camera image and open the adhesions mechanically during epiduroscopy, saline is injected continuously in the epidural area. As a result, an increase in intracranial pressure is to be expected in theory. Increased intracranial pressure can be evaluated by measuring by optic nerve sheath diameter. Objectives: This study was designed to evaluate the relationship between optic nerve sheath diameter measurements and intracranial pressure, after injecting fluid to the epidural area during epiduroscopy procedures performed in our clinic. Study design: Retrospective study. Setting: Sakarya University Training and Research Hospital. Methods: During the epiduroscopy procedure, pre and postoperative bilateral optic nerve sheath diameters were measured with an ultrasonography probe. With the patients' eyelids closed, the probe was placed on the orbita in the sagittal plane, measuring 3 mm posterior of the papilla. Results: While there was a statistically significant difference between pre- and post-operative optic nerve sheath diameter measurements, there was no significant correlation with processing time, amount of fluid delivered, or fluid delivery rates. Limitations: One of the limitations of this study is the retrospective collection of data. A second limitation is that repetitive measurements were not performed, instead of a single postoperative measurement. Conclusion: We think more prospective randomized controlled studies are required to examine the increase in the diameter of the optic nerve sheath, which is an indirect indicator of increased intracranial pressure after epiduroscopy applications, in order to determine whether the pressure increase is associated with the rate of fluid delivery, the total fluid amount, or the processing time.
MeSH term(s)	Diskectomy ; Humans ; Intracranial Hypertension/diagnostic imaging ; Intracranial Pressure ; Lasers ; Optic Nerve/diagnostic imaging ; Prospective Studies ; Retrospective Studies ; Ultrasonography
Language	English
Publishing date	2021-07-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2146393-1
ISSN	2150-1149 ; 1533-3159
ISSN (online)	2150-1149
ISSN	1533-3159
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