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Article ; Online: Anisotropic 2D excitons unveiled in organic-inorganic quantum wells.

Maserati, Lorenzo / Refaely-Abramson, Sivan / Kastl, Christoph / Chen, Christopher T / Borys, Nicholas J / Eisler, Carissa N / Collins, Mary S / Smidt, Tess E / Barnard, Edward S / Strasbourg, Matthew / Schriber, Elyse A / Shevitski, Brian / Yao, Kaiyuan / Hohman, J Nathan / Schuck, P James / Aloni, Shaul / Neaton, Jeffrey B / Schwartzberg, Adam M

Materials horizons

2020 Volume 8, Issue 1, Page(s) 197–208

Abstract: Two-dimensional (2D) excitons arise from electron-hole confinement along one spatial dimension. Such excitations are often described in terms of Frenkel or Wannier limits according to the degree of exciton spatial localization and the surrounding ... ...

Abstract	Two-dimensional (2D) excitons arise from electron-hole confinement along one spatial dimension. Such excitations are often described in terms of Frenkel or Wannier limits according to the degree of exciton spatial localization and the surrounding dielectric environment. In hybrid material systems, such as the 2D perovskites, the complex underlying interactions lead to excitons of an intermediate nature, whose description lies somewhere between the two limits, and a better physical description is needed. Here, we explore the photophysics of a tuneable materials platform where covalently bonded metal-chalcogenide layers are spaced by organic ligands that provide confinement barriers for charge carriers in the inorganic layer. We consider self-assembled, layered bulk silver benzeneselenolate, [AgSePh]
Language	English
Publishing date	2020-07-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2744250-0
ISSN	2051-6355 ; 2051-6347
ISSN (online)	2051-6355
ISSN	2051-6347
DOI	10.1039/c9mh01917k
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Article ; Online: The use of a hybrid dynamic stabilization and fusion system in the lumbar spine: preliminary experience.

Maserati, Matthew B / Tormenti, Matthew J / Panczykowski, David M / Bonfield, Christopher M / Gerszten, Peter C

Neurosurgical focus

2010 Volume 28, Issue 6, Page(s) E2

Abstract: Object: The authors report the use and preliminary results of a novel hybrid dynamic stabilization and fusion construct for the surgical treatment of degenerative lumbar spine pathology.: Methods: The authors performed a retrospective chart review of ...

Abstract	Object: The authors report the use and preliminary results of a novel hybrid dynamic stabilization and fusion construct for the surgical treatment of degenerative lumbar spine pathology. Methods: The authors performed a retrospective chart review of all patients who underwent posterior lumbar instrumentation with the Dynesys-to-Optima (DTO) hybrid dynamic stabilization and fusion system. Preoperative symptoms, visual analog scale (VAS) pain scores, perioperative complications, and the need for subsequent revision surgery were recorded. Each patient was then contacted via telephone to determine current symptoms and VAS score. Follow-up was available for 22 of 24 patients, and the follow-up period ranged from 1 to 22 months. Clinical outcome was gauged by comparing VAS scores prior to surgery and at the time of telephone interview. Results: A total of 24 consecutive patients underwent lumbar arthrodesis surgery in which the hybrid system was used for adjacent-level dynamic stabilization. The mean preoperative VAS score was 8.8, whereas the mean postoperative VAS score was 5.3. There were five perioperative complications that included 2 durotomies and 2 wound infections. In addition, 1 patient had a symptomatic medially placed pedicle screw that required revision. These complications were not thought to be specific to the DTO system itself. In 3 patients treatment failed, with treatment failure being defined as persistent preoperative symptoms requiring reoperation. Conclusions: The DTO system represents a novel hybrid dynamic stabilization and fusion construct. The technique holds promise as an alternative to multilevel lumbar arthrodesis while potentially decreasing the risk of adjacent-segment disease following lumbar arthrodesis. The technology is still in its infancy and therefore follow-up, when available, remains short. The authors report their preliminary experience using a hybrid system in 24 patients, along with short-interval clinical and radiographic follow-up.
MeSH term(s)	Adult ; Aged ; Diskectomy/instrumentation ; Diskectomy/methods ; Female ; Humans ; Internal Fixators/adverse effects ; Internal Fixators/standards ; Internal Fixators/statistics & numerical data ; Intervertebral Disc Displacement/pathology ; Intervertebral Disc Displacement/physiopathology ; Intervertebral Disc Displacement/surgery ; Joint Instability/pathology ; Joint Instability/physiopathology ; Joint Instability/surgery ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/pathology ; Lumbar Vertebrae/surgery ; Male ; Middle Aged ; Neurosurgical Procedures/instrumentation ; Neurosurgical Procedures/methods ; Outcome Assessment (Health Care) ; Postoperative Complications/etiology ; Postoperative Complications/physiopathology ; Prosthesis Implantation/methods ; Radiculopathy/pathology ; Radiculopathy/physiopathology ; Radiculopathy/surgery ; Radiography ; Retrospective Studies ; Spinal Fusion/instrumentation ; Spinal Fusion/methods ; Spondylosis/pathology ; Spondylosis/physiopathology ; Spondylosis/surgery ; Treatment Outcome
Language	English
Publishing date	2010-06
Publishing country	United States
Document type	Journal Article ; Webcasts
ZDB-ID	2026589-X
ISSN	1092-0684 ; 1092-0684
ISSN (online)	1092-0684
ISSN	1092-0684
DOI	10.3171/2010.3.FOCUS1055
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Article ; Online: Complications and radiographic correction in adult scoliosis following combined transpsoas extreme lateral interbody fusion and posterior pedicle screw instrumentation.

Tormenti, Matthew J / Maserati, Matthew B / Bonfield, Christopher M / Okonkwo, David O / Kanter, Adam S

Neurosurgical focus

2010 Volume 28, Issue 3, Page(s) E7

Abstract: Object: The authors recently used a combined approach of minimally invasive transpsoas extreme lateral interbody fusion (XLIF) and open posterior segmental pedicle screw instrumentation with transforaminal lumbar interbody fusion (TLIF) for the ... ...

Abstract	Object: The authors recently used a combined approach of minimally invasive transpsoas extreme lateral interbody fusion (XLIF) and open posterior segmental pedicle screw instrumentation with transforaminal lumbar interbody fusion (TLIF) for the correction of coronal deformity. The complications and radiographic outcomes were compared with a posterior-only approach for scoliosis correction. Methods: The authors retrospectively reviewed all deformity cases that were surgically corrected at the University of Pittsburgh Medical Center Presbyterian Hospital between June 2007 and August 2009. Eight patients underwent combined transpsoas and posterior approaches for adult degenerative thoracolumbar scoliosis. The comparison group consisted of 4 adult patients who underwent a posterior-only scoliosis correction. Data on intra- and postoperative complications were collected. The pre- and postoperative posterior-anterior and lateral scoliosis series radiographic films were reviewed, and comparisons were made for coronal deformity, apical vertebral translation (AVT), and lumbar lordosis. Clinical outcomes were evaluated by comparing pre- and postoperative visual analog scale scores. Results: The median preoperative coronal Cobb angle in the combined approach was 38.5 degrees (range 18-80 degrees). Following surgery, the median Cobb angle was 10 degrees (p < 0.0001). The mean preoperative AVT was 3.6 cm, improving to 1.8 cm postoperatively (p = 0.031). The mean preoperative lumbar lordosis in this group was 47.3 degrees, and the mean postoperative lordosis was 40.4 degrees. Compared with posterior-only deformity corrections, the mean values for curve correction were higher for the combined approach than for the posterior-only approach. Conversely, the mean AVT correction was higher in the posterior-only group. One patient in the posterior-only group required revision of the instrumentation. One patient who underwent the transpsoas XLIF approach suffered an intraoperative bowel injury necessitating laparotomy and segmental bowel resection; this patient later underwent an uneventful posterior-only correction of her scoliotic deformity. Two patients (25%) in the XLIF group sustained motor radiculopathies, and 6 of 8 patients (75%) experienced postoperative thigh paresthesias or dysesthesias. Motor radiculopathy resolved in 1 patient, but persisted 3 months postsurgery in the other. Sensory symptoms persisted in 5 of 6 patients at the most recent follow-up evaluation. The mean clinical follow-up time was 10.5 months for the XLIF group and 11.5 months for the posterior-only group. The mean visual analog scale score decreased from 8.8 to 3.5 in the XLIF group, and it decreased from 9.5 to 4 in the posterior-only group. Conclusions: Radiographic outcomes such as the Cobb angle and AVT were significantly improved in patients who underwent a combined transpsoas and posterior approach. Lumbar lordosis was maintained in all patients undergoing the combined approach. The combination of XLIF and TLIF/posterior segmental instrumentation techniques may lead to less blood loss and to radiographic outcomes that are comparable to traditional posterior-only approaches. However, the surgical technique carries significant risks that require further evaluation and proper informed consent.
MeSH term(s)	Adult ; Age Factors ; Aged ; Bone Screws ; Bone Transplantation/methods ; Follow-Up Studies ; Humans ; Internal Fixators ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Middle Aged ; Orthopedic Procedures/methods ; Postoperative Complications/etiology ; Radiculopathy/diagnostic imaging ; Radiculopathy/etiology ; Scoliosis/diagnostic imaging ; Scoliosis/surgery ; Spinal Fusion/methods ; Spine/diagnostic imaging ; Spine/surgery ; Thoracic Vertebrae/diagnostic imaging ; Thoracic Vertebrae/surgery ; Tomography, X-Ray Computed ; Transplantation, Autologous/methods ; Treatment Outcome
Language	English
Publishing date	2010-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2026589-X
ISSN	1092-0684 ; 1092-0684
ISSN (online)	1092-0684
ISSN	1092-0684
DOI	10.3171/2010.1.FOCUS09263
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Article ; Online: Perioperative surgical complications of transforaminal lumbar interbody fusion: a single-center experience.

Tormenti, Matthew J / Maserati, Matthew B / Bonfield, Christopher M / Gerszten, Peter C / Moossy, John J / Kanter, Adam S / Spiro, Richard M / Okonkwo, David O

Journal of neurosurgery. Spine

2012 Volume 16, Issue 1, Page(s) 44–50

Abstract: Object: Since its original description in 1982, transforaminal lumbar interbody fusion (TLIF) has grown in popularity as a means for achieving circumferential fusion. The authors sought to define the perioperative complication rates of the TLIF ... ...

Abstract	Object: Since its original description in 1982, transforaminal lumbar interbody fusion (TLIF) has grown in popularity as a means for achieving circumferential fusion. The authors sought to define the perioperative complication rates of the TLIF procedure at a large academic medical center. Methods: For all eligible patients from a consecutive series of 531 TLIF procedures, the institution's complication database and the medical record were reviewed to identify complications. Medical, nonprocedure-related complications such as myocardial infarction and pulmonary embolism were excluded due to inconsistency in the recording of these complications in the database. Rates were calculated for each type of complication, and subgroup analysis was performed to investigate the effect of previous lumbar surgery, and of multilevel versus single-level interbody fusion on complication rates. Odds ratios were calculated and evaluated using chi-square analysis. Results: Five hundred thirty-one patients underwent a TLIF procedure during the study period. Two hundred forty-four patients (46%) had undergone a previous lumbar operation. Interbody fusion was performed at 1 level in 317 patients, at 2 levels in 188 patients, at 3 levels in 24 patients, and at 4 levels in 2 patients. One hundred thirty-five patients (25.4%) had at least one procedure-related complication. The most common complications were durotomy (14.3% of patients) and infection (3.8% of patients). Symptomatic screw misplacement (2.1% of patients) and interbody cage migration (1.8% of patients) were less common complications. The overall complication rate was greater in those patients who had undergone a previous operation (OR 1.75, 95% CI 1.18-2.59; p < 0.01) and in those who had multilevel surgery (OR 1.54, 95 % CI 1.04-2.28; p = 0.03), and the incidence of durotomy was higher in patients who had a previous operation (OR 1.75, 95% CI 1.07-2.87; p = 0.03). These differences were statistically significant. Durotomy also occurred more frequently in patients who had multilevel interbody fusion (OR 1.49, 95% CI 0.92-2.43; p = 0.13). A trend toward higher infection rates in those patients who underwent multilevel interbody fusion was observed (OR 1.5, 95% CI 0.62-3.68; p = 0.49), but this was not statistically significant. Infection rates did not differ between revision and first-time surgeries. Conclusions: Transforaminal lumbar interbody fusion has gained widespread popularity as a procedure for achieving arthrodesis in the lumbar spine. Complications occurred more often in patients undergoing revision surgery or multilevel interbody fusion. Durotomy and infection were the most common complications in this series.
MeSH term(s)	Bone Screws ; Dura Mater/injuries ; Humans ; Intraoperative Complications/epidemiology ; Lumbar Vertebrae/surgery ; Postoperative Complications/epidemiology ; Prevalence ; Retrospective Studies ; Spinal Fusion/adverse effects
Language	English
Publishing date	2012-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2158643-3
ISSN	1547-5646 ; 1547-5654
ISSN (online)	1547-5646
ISSN	1547-5654
DOI	10.3171/2011.9.SPINE11373
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Article ; Online: Occipital condyle fractures: clinical decision rule and surgical management.

Maserati, Matthew B / Stephens, Bradley / Zohny, Zohny / Lee, Joon Y / Kanter, Adam S / Spiro, Richard M / Okonkwo, David O

Journal of neurosurgery. Spine

2009 Volume 11, Issue 4, Page(s) 388–395

Abstract: Object: Occipital condyle fractures (OCFs) are rare injuries and their treatment remains controversial. Several classification systems have been proposed, first by Anderson and Montesano and more recently by Tuli and colleagues and Hanson and associates, ...

Abstract	Object: Occipital condyle fractures (OCFs) are rare injuries and their treatment remains controversial. Several classification systems have been proposed, first by Anderson and Montesano and more recently by Tuli and colleagues and Hanson and associates, who sought to stratify these fractures in a manner that would guide treatment that has typically ranged from semirigid collar immobilization to halo fixation or occipitocervical fusion. It has been the authors' impression, based on experience with OCFs at their institution, that classification is cumbersome and contributes little to the clinical decision-making process, while the identification of craniocervical misalignment and neural element compromise is paramount, and sufficient, for the planning of treatment. Methods: The authors performed a retrospective review of 24,745 consecutive trauma presentations to a single Level I trauma center (UPMC Presbyterian Hospital) over a 6-year period, identifying 100 patients with 106 OCFs. All patients were evaluated by the spine trauma service and underwent imaging of the craniocervical junction using reconstructed CT scans. Patient characteristics, fracture characteristics (including fracture classification according to the 2 major classification systems), initial management, and status at follow-up were recorded. Results: The incidence of OCF in this trauma population was 0.4%. Two patients had evidence of craniocervical misalignment on reconstructed CT imaging at the time of admission; both patients underwent occipitocervical fusion. One patient underwent occipitocervical fusion for unrelated C1-2 fractures. The remainder of those surviving to discharge, whose fractures represented all fracture subtypes, received treatment with a rigid cervical collar or counseling alone. No patients, including 4 patients with bilateral OCFs, were found to have developed delayed craniocervical instability or misalignment on follow-up, or to require further neurosurgical intervention for an OCF. Neural element compression was not identified in any of the patients, and there were no cases of delayed cranial neuropathy. Conclusions: Beyond the identification of craniocervical misalignment on reconstructed CT scans at admission, further classification of OCFs is unnecessary. Management should consist of up-front occipitocervical fusion or halo fixation in cases demonstrating occipitocervical misalignment, or of immobilization in a rigid cervical collar followed by delayed clinical and radiographic evaluation in a spine trauma clinic if misalignment is not present.
MeSH term(s)	Adult ; Algorithms ; Atlanto-Occipital Joint/diagnostic imaging ; Atlanto-Occipital Joint/injuries ; Atlanto-Occipital Joint/surgery ; Cervical Vertebrae/surgery ; Decision Making ; Female ; Follow-Up Studies ; Humans ; Incidence ; Male ; Occipital Bone/diagnostic imaging ; Occipital Bone/injuries ; Occipital Bone/surgery ; Retrospective Studies ; Skull Fractures/diagnostic imaging ; Skull Fractures/mortality ; Skull Fractures/surgery ; Spinal Fusion/methods ; Tomography, X-Ray Computed
Language	English
Publishing date	2009-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2158643-3
ISSN	1547-5646 ; 1547-5654
ISSN (online)	1547-5646
ISSN	1547-5654
DOI	10.3171/2009.5.SPINE08866
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Article ; Online: Guideline summary review: An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis.

The spine journal : official journal of the North American Spine Society

2016 Volume 16, Issue 3, Page(s) 439–448

Abstract: Background context: The North American Spine Society's (NASS) Evidence-Based Clinical Guideline for the Diagnosis and Treatment of Degenerative Lumbar Spondylolisthesis features evidence-based recommendations for diagnosing and treating degenerative ... ...

Abstract	Background context: The North American Spine Society's (NASS) Evidence-Based Clinical Guideline for the Diagnosis and Treatment of Degenerative Lumbar Spondylolisthesis features evidence-based recommendations for diagnosing and treating degenerative lumbar spondylolisthesis. The guideline updates the 2008 guideline on this topic and is intended to reflect contemporary treatment concepts for symptomatic degenerative lumbar spondylolisthesis as reflected in the highest quality clinical literature available on this subject as of May 2013. The NASS guideline on this topic is the only guideline on degenerative lumbar spondylolisthesis included in the Agency for Healthcare Research and Quality's National Guideline Clearinghouse (NGC). Purpose: The purpose of this guideline is to provide an evidence-based educational tool to assist spine specialists when making clinical decisions for patients with degenerative lumbar spondylolisthesis. This article provides a brief summary of the evidence-based guideline recommendations for diagnosing and treating patients with this condition. Study design: A systematic review of clinical studies relevant to degenerative spondylolisthesis was carried out. Methods: This NASS spondyolisthesis guideline is the product of the Degenerative Lumbar Spondylolisthesis Work Group of NASS' Evidence-Based Guideline Development Committee. The methods used to develop this guideline are detailed in the complete guideline and technical report available on the NASS website. In brief, a multidisciplinary work group of spine care specialists convened to identify clinical questions to address in the guideline. The literature search strategy was developed in consultation with medical librarians. Upon completion of the systematic literature search, evidence relevant to the clinical questions posed in the guideline was reviewed. Work group members used the NASS evidentiary table templates to summarize study conclusions, identify study strengths and weaknesses, and assign levels of evidence. Work group members participated in webcasts and in-person recommendation meetings to update and formulate evidence-based recommendations and incorporate expert opinion when necessary. The draft guidelines were submitted to an internal peer review process and ultimately approved by the NASS Board of Directors. Upon publication, the Degenerative Lumbar Spondylolisthesis guideline was accepted into the NGC and will be updated approximately every 5 years. Results: Twenty-seven clinical questions were addressed in this guideline update, including 15 clinical questions from the original guideline and 12 new clinical questions. The respective recommendations were graded by strength of the supporting literature, which was stratified by levels of evidence. Twenty-one new or updated recommendations or consensus statements were issued and 13 recommendations or consensus statements were maintained from the original guideline. Conclusions: The clinical guideline was created using the techniques of evidence-based medicine and best available evidence to aid practitioners in the care of patients with degenerative lumbar spondylolisthesis. The entire guideline document, including the evidentiary tables, literature search parameters, literature attrition flow chart, suggestions for future research, and all of the references, is available electronically on the NASS website at https://www.spine.org/Pages/ResearchClinicalCare/QualityImprovement/ClinicalGuidelines.aspx and will remain updated on a timely schedule.
MeSH term(s)	Evidence-Based Medicine ; Humans ; Injections, Intra-Articular ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Neurosurgical Procedures ; North America ; Physical Therapy Modalities ; Societies, Medical ; Spine ; Spondylolisthesis/diagnostic imaging ; Spondylolisthesis/therapy
Language	English
Publishing date	2016-03
Publishing country	United States
Document type	Journal Article ; Practice Guideline ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Review
ZDB-ID	2037072-6
ISSN	1878-1632 ; 1529-9430
ISSN (online)	1878-1632
ISSN	1529-9430
DOI	10.1016/j.spinee.2015.11.055
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Article ; Online: Anisotropic 2D excitons unveiled in organic-inorganic quantum wells.

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Article ; Online: The use of a hybrid dynamic stabilization and fusion system in the lumbar spine: preliminary experience.

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Article ; Online: Complications and radiographic correction in adult scoliosis following combined transpsoas extreme lateral interbody fusion and posterior pedicle screw instrumentation.

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Article ; Online: Perioperative surgical complications of transforaminal lumbar interbody fusion: a single-center experience.

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Article ; Online: Occipital condyle fractures: clinical decision rule and surgical management.

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Article ; Online: Guideline summary review: An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis.

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