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  1. Article ; Online: Reply: Antibiotic therapy in preterm premature rupture of the membranes.

    Sung, Ji-Hee / Oh, Soo-Young

    American journal of obstetrics & gynecology MFM

    2023  Volume 5, Issue 6, Page(s) 100926

    MeSH term(s) Infant, Newborn ; Female ; Humans ; Anti-Bacterial Agents/therapeutic use ; Fetal Membranes, Premature Rupture/diagnosis ; Fetal Membranes, Premature Rupture/drug therapy ; Fetal Membranes, Premature Rupture/epidemiology ; Premature Birth
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-24
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2023.100926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hydroxychloroquine in obstetrics: potential implications of the prophylactic use of hydroxychloroquine for placental insufficiency during pregnancy.

    Kim, Yoo-Min / Sung, Ji-Hee / Cha, Hyun-Hwa / Oh, Soo-Young

    Obstetrics & gynecology science

    2024  Volume 67, Issue 2, Page(s) 143–152

    Abstract: Proper placentation during early pregnancy is a key factor for maintaining a healthy pregnancy. Placental insufficiency leads to critical complications such as preeclampsia, fetal growth restriction, and fetal demise. These complications are often ... ...

    Abstract Proper placentation during early pregnancy is a key factor for maintaining a healthy pregnancy. Placental insufficiency leads to critical complications such as preeclampsia, fetal growth restriction, and fetal demise. These complications are often associated with pathological findings of restricted remodeling and obstructive lesions of the myometrial spiral arteries, which have high recurrence rates during subsequent pregnancies. Currently, there are no pharmacological interventions other than aspirin for the prevention of preeclampsia. Hydroxychloroquine (HCQ), a well-known antimalarial drug, reduces inflammatory and thrombotic changes in vessels. For decades, the use of HCQ for autoimmune diseases has resulted in the successful prevention of both arterial and venous thrombotic events and has been extended to the treatment of lupus and antiphospholipid antibody syndrome during pregnancy. HCQ reduces the risk of preeclampsia with lupus by up to 90%. Several recent studies have investigated whether HCQ improves pregnancy outcomes in women with a history of poor outcomes. In addition, in vitro and animal studies have demonstrated the beneficial effects of HCQ in improving endothelial dysfunction and alleviating hypertension and proteinuria. Therefore, we hypothesized that HCQ has the potential to attenuate the vascular inflammatory and thrombogenic pathways associated with placental insufficiency and conducted a multicenter clinical trial on the efficacy of combining aspirin with HCQ for pregnancies at high risk for preeclampsia in Korea. This study summarizes the potential effects of HCQ on pregnancies with placental insufficiency and the implications of HCQ treatment in the field of obstetrics.
    Language English
    Publishing date 2024-01-19
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2814367-X
    ISSN 2287-8580 ; 2287-8572
    ISSN (online) 2287-8580
    ISSN 2287-8572
    DOI 10.5468/ogs.23252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Atypical antidepressant mirtazapine inhibits 5-hydroxytryptamine3 receptor currents in NCB-20 cells.

    Park, Yong Soo / Oh, Haejung / Sung, Ki-Wug

    Journal of pharmacological sciences

    2022  Volume 151, Issue 2, Page(s) 63–71

    Abstract: Mirtazapine, an atypical antidepressant, is known to enhance serotonergic transmission by inhibiting the 5-hydroxytryptamine (5-HT) ...

    Abstract Mirtazapine, an atypical antidepressant, is known to enhance serotonergic transmission by inhibiting the 5-hydroxytryptamine (5-HT)
    MeSH term(s) Antidepressive Agents/pharmacology ; Antidepressive Agents, Second-Generation ; Cell Line, Tumor ; Mirtazapine ; Receptors, Serotonin, 5-HT3 ; Serotonin/pharmacology ; Animals ; Cricetinae ; Cricetulus
    Chemical Substances Antidepressive Agents ; Antidepressive Agents, Second-Generation ; Mirtazapine (A051Q2099Q) ; Receptors, Serotonin, 5-HT3 ; Serotonin (333DO1RDJY)
    Language English
    Publishing date 2022-12-05
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2104264-0
    ISSN 1347-8648 ; 1347-8613
    ISSN (online) 1347-8648
    ISSN 1347-8613
    DOI 10.1016/j.jphs.2022.12.002
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  4. Article ; Online: Bilateral Nostril Abrasion in Endoscopic Sinus Surgery with Micodebrider.

    Oh, Eun Jung / Kim, Jung Soo / Heo, Sung Jae

    The Journal of craniofacial surgery

    2023  

    Abstract: The emergence of microdebrider technology has revolutionized endoscopic sinus surgery (ESS). Although widely used, it has been associated with complications such as cerebrospinal fluid leakage, ocular and brain injuries, and synechia formation. However, ... ...

    Abstract The emergence of microdebrider technology has revolutionized endoscopic sinus surgery (ESS). Although widely used, it has been associated with complications such as cerebrospinal fluid leakage, ocular and brain injuries, and synechia formation. However, reports on cases of skin abrasion associated with the use of microdebriders in ESS are scarce. We herein present a unique observation of bilateral nostril abrasion after ESS using the microdebrider in a 53-year-old man. The patient underwent ESS and septoplasty for nasal obstruction and polyps. Bilateral nostril erythema and skin abrasion were observed after surgery, which resolved without scarring. Nostril abrasion is attributed to the lever-like use of the microdebrider against the medial aspect of the nostril during the procedure, particularly among inexperienced surgeons. This prompts the need for a cautious approach when using microdebriders in ESS to minimize complications. Increased awareness and precautionary measures can enhance the safety of microdebriders in ESS.
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000009757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chemical Burn Injury on the Cornea Following Skin Preparation With Chlorhexidine in Tonsillectomy and Adenoidectomy.

    Oh, Eun Jung / Kim, Jung Soo / Heo, Sung Jae

    The Journal of craniofacial surgery

    2023  

    Abstract: This article report discusses a pediatric patient who suffered a corneal chemical burn injury after tonsillectomy and adenoidectomy surgery due to skin preparation with chlorhexidine. In this case, inadequate sealing of the eye shield during skin ... ...

    Abstract This article report discusses a pediatric patient who suffered a corneal chemical burn injury after tonsillectomy and adenoidectomy surgery due to skin preparation with chlorhexidine. In this case, inadequate sealing of the eye shield during skin preparation allowed the chlorhexidine-alcohol solution to accumulate at its edge and gradually penetrate, resulting in the corneal injury. Prompt ophthalmological intervention and appropriate eye care treatment led to a gradual improvement in the patient's symptoms. The authors aim to present the case, share the revisions made to our skin preparation policy, and emphasize the importance of cautious antiseptic use to minimize the risk of adverse events. Adverse effects of chlorhexidine, such as hypersensitivity reactions and burns, including corneal damage, are highlighted. Health care providers should exercise caution when selecting and applying antiseptics, considering patient-specific factors, and comprehensive training should be provided to promote adherence to safe antiseptic practices during surgical procedures.
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000009755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Metastatic Histiocytic Sarcoma with Secondary Involvement of the Skin: A Case Report.

    Seo, Hyun-Min / Park, Ji Hun / Song, Seon Young / Oh, Se Uk / Park, Se Kwang / Han, Sung Soo / Kim, Joung Soo

    Indian journal of dermatology

    2024  Volume 68, Issue 6, Page(s) 682–685

    Abstract: Histiocytic sarcoma (HS) is a rare malignant neoplasm of presumed hematopoietic origin, showing morphologic and immunophenotypic evidence of histiocytic differentiation. A 61-year-old woman presented with an abdominal mass. She had a history of HS in ... ...

    Abstract Histiocytic sarcoma (HS) is a rare malignant neoplasm of presumed hematopoietic origin, showing morphologic and immunophenotypic evidence of histiocytic differentiation. A 61-year-old woman presented with an abdominal mass. She had a history of HS in both adrenal glands. The tumour cells of the left adrenal gland were very large epithelioid cells with abundant eosinophilic cytoplasm and large, round-to-oval nuclei. Similarly, the cutaneous lesion of the skin was composed of polygonal cells with well-defined cell borders and high nuclear/cytoplasm (N/C) ratios. Immunohistochemically, both tumours were positive for histiocyte-associated antigens but negative for epithelial, melanocyte, lymphoid, dendritic, and Langerhansl nuclei. Similarly, the cutaneous lesion of the skin was composenose correctly. It is important to recognise the morphological features and immunohistochemical characteristics of metastatic cells in order to achieve accurate diagnoses.
    Language English
    Publishing date 2024-01-09
    Publishing country India
    Document type Case Reports
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.ijd_245_23
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  7. Article ; Online: Efficient disruption of CmHk1 using CRISPR/Cas9 ribonucleoprotein delivery in Cordyceps militaris.

    Choi, Hyeongju / Park, Sung-Won / Oh, Junsang / Kim, Cheol Soo / Sung, Gi-Ho / Sang, Hyunkyu

    FEMS microbiology letters

    2023  Volume 370

    Abstract: Cordyceps militaris, an entomopathogenic ascomycete, produces edible medicinal mushrooms known to have medicinal and therapeutic functions. To develop the genetic transformation system in C. militaris, green fluorescent protein (GFP) mutants of C. ... ...

    Abstract Cordyceps militaris, an entomopathogenic ascomycete, produces edible medicinal mushrooms known to have medicinal and therapeutic functions. To develop the genetic transformation system in C. militaris, green fluorescent protein (GFP) mutants of C. militaris were generated by PEG-mediated protoplast transformation. The CRISPR/Cas9 ribonucleoprotein (RNP) targeting the class III histidine kinase of C. militaris (CmHk1) was then delivered into protoplasts of C. militaris through the transformation system. Mutations induced by the RNP in selected mutants were detected: 1 nt deletion (6 mutants), 3 nt deletion with substitution of 1 nt (1 mutant), insertion of 85 nts (1 mutant), 41 nts (2 mutants), and 35 nts (5 mutants). An in vitro sensitivity assay of the mutants indicated that knockout of CmHk1 reduced sensitivity to two fungicides, iprodione and fludioxonil, but increased sensitivity to osmotic stresses compared to the wild type. Summing up, the CRISPR/Cas9 RNP delivery system was successfully developed, and our results revealed that CmHk1 was involved in the fungicide resistance and osmotic stress in C. militaris.
    MeSH term(s) CRISPR-Cas Systems ; Cordyceps/genetics ; Ribonucleoproteins/genetics ; Mutation
    Chemical Substances Ribonucleoproteins
    Language English
    Publishing date 2023-07-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752343-9
    ISSN 1574-6968 ; 0378-1097
    ISSN (online) 1574-6968
    ISSN 0378-1097
    DOI 10.1093/femsle/fnad072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correction to "Adjusted Bulk and Interfacial Properties in Highly Stable Semitransparent Perovskite Solar Cells Fabricated by Thermocompression Bonding between Perovskite Layers".

    Jung, Hee-Yun / Oh, Eun Sung / Kim, Dong Jun / Shim, Hongjae / Lee, Wonjong / Yoon, Soon-Gil / Lim, Jongchul / Yun, Jae Sung / Kim, Taek-Soo / Yang, Tae-Youl

    ACS applied materials & interfaces

    2024  Volume 16, Issue 8, Page(s) 11146

    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Published Erratum
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c01081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correction: Deep learning-based metastasis detection in patients with lung cancer to enhance reproducibility and reduce workload in brain metastasis screening with MRI: a multi-center study.

    Park, Yae Won / Park, Ji Eun / Ahn, Sung Soo / Han, Kyunghwa / Kim, NakYoung / Oh, Joo Young / Lee, Da Hyun / Won, So Yeon / Shin, Ilah / Kim, Ho Sung / Lee, Seung-Koo

    Cancer imaging : the official publication of the International Cancer Imaging Society

    2024  Volume 24, Issue 1, Page(s) 41

    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2104862-9
    ISSN 1470-7330 ; 1470-7330
    ISSN (online) 1470-7330
    ISSN 1470-7330
    DOI 10.1186/s40644-024-00688-6
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  10. Article ; Online: Pesticide Exposure in Relation to the Incidence of Abnormal Glucose Regulation: A Retrospective Cohort Study.

    Kim, Sung-Kyung / Oh, Hyun-Jung / Oh, Sung-Soo / Koh, Sang-Baek

    International journal of environmental research and public health

    2022  Volume 19, Issue 12

    Abstract: Diabetes and prediabetes (called abnormal glucose regulation (AGR)) are adverse health effects associated with exposure to pesticides. However, there are few epidemiological studies on the relationship between pesticide use and the incidence of AGR. We ... ...

    Abstract Diabetes and prediabetes (called abnormal glucose regulation (AGR)) are adverse health effects associated with exposure to pesticides. However, there are few epidemiological studies on the relationship between pesticide use and the incidence of AGR. We examined the causal relationship between pesticide use and AGR incidence in a rural population using data from a Korean Farmers' Cohort study of 1076 participants. Poisson regression with robust error variance was used to calculate the relative risks (RR) and 95% confidence intervals (CI) to estimate the relationship between pesticide exposure and AGR. The incidence of AGR in the pesticide-exposed group was 29.1%. Pesticide use increased the RR of AGR (RR 1.32, 95% CI 1.03-1.69). We observed a low-dose effect related to exposure of pesticides to AGR and a U-shaped dose-response relationship in men. Pesticide exposure is related to the incidence of AGR, and the causal relationship differs between men and women.
    MeSH term(s) Agriculture ; Cohort Studies ; Female ; Glucose ; Humans ; Incidence ; Male ; Occupational Exposure/adverse effects ; Pesticides/toxicity ; Retrospective Studies
    Chemical Substances Pesticides ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-06-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19127550
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