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Article ; Online: Two new species of the genus Macromotettixoides Zheng, Wei & Jiang (Orthoptera: Tetrigidae: Metrodorinae) from China

Wei, Shi-Zhen / Deng, Wei-an

Oriental Insects. 2023 Apr. 03, v. 57, no. 2 p.626-642

2023

Abstract: New species, Macromotettixoides daweishana sp. nov. from Yunnan and Macromotettixoides orthomargina sp. nov. from Sichuan, are described and illustrated. M. daweishana is similar to M. undulatifemura but differs in the shape of pronotum and narrow vertex. ...

Abstract	New species, Macromotettixoides daweishana sp. nov. from Yunnan and Macromotettixoides orthomargina sp. nov. from Sichuan, are described and illustrated. M. daweishana is similar to M. undulatifemura but differs in the shape of pronotum and narrow vertex. M. orthomargina is similar to M. shengtangshanensis but differs in the shape of infrascapular area and the wide vertex. The distribution and a key to the species of Macromotettixoides are given. http://www.zoobank.org/urn:lsid:zoobank.org:pub:38128DB6-2DFB-4C8B-9AD4-6B773B9EA8F3
Keywords	Tetrigidae ; new species ; taxonomic keys ; China ; Tetrigoidea ; pygmy grasshoppers ; taxonomy ; Yunnan ; Sichuan
Language	English
Dates of publication	2023-0403
Size	p. 626-642.
Publishing place	Taylor & Francis
Document type	Article ; Online
ISSN	2157-8745
DOI	10.1080/00305316.2022.2098198
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: The Gut Microbial Co-Abundance Gene Groups (CAGs) Differentially Respond to the Flavor (Yao-Wei) of Chinese Materia Medica.

Yang, Ya-Nan / Deng, Yu-Ting / Zang, Chen-Chen / Zhang, Fang / Huang, Zi-Bao / Dong, Lin / Lu, Wei-Ying / Zhang, Xiao-Po / Wu, Chong-Ming

The American journal of Chinese medicine

2022 Volume 50, Issue 8, Page(s) 2223–2244

Abstract: The property theory is a unique principle instructing traditional Chinese doctors to prescribe proper medicines against diseases. As an essential part of it, the five-flavor theory catalogs various Chinese materia medicas (CMMs) into five flavors (sweet, ...

Abstract	The property theory is a unique principle instructing traditional Chinese doctors to prescribe proper medicines against diseases. As an essential part of it, the five-flavor theory catalogs various Chinese materia medicas (CMMs) into five flavors (sweet, bitter, sour, salty, and pungent) based on their taste and medical functions. Although CMM has been successfully applied in China for thousands of years, it is still a big challenge to interpret CMM flavor via modern biomarkers, further deepening its elusiveness. Herein, to identify the correlation between gut microbiota and CMM flavor, we selected 14 CMMs with different flavors to prepare their aqueous extracts, quantified the contained major chemical components, and then performed full-length 16S rRNA sequencing to analyze the gut microbiota of C57BL/6 mice administrated with CMM extracts. We found that flavones, alkaloids, and saponins were the richest components for sweet-, bitter-, and pungent-flavored CMMs, respectively. Medicines with merged flavors (bitter-pungent and sweet-pungent) displayed mixed profiles of components. According to gut microbial analysis, modulation of CMMs belonging to the same flavor on the taxonomic classification was inconsistent to an extent, while the functional sets of gut microbiota, co-abundance gene groups (CAGs), strongly and differentially responded to distinct flavors. Moreover, these correlations were in line with their pharmacological actions. Therefore, the gut microbial functional sets (CAGs) could act as the possible indicator to reflect CMM flavor, rather than the composition of microbial community.
MeSH term(s)	Mice ; Animals ; Materia Medica ; Medicine, Chinese Traditional ; Gastrointestinal Microbiome/genetics ; RNA, Ribosomal, 16S/genetics ; Mice, Inbred C57BL
Chemical Substances	Materia Medica ; RNA, Ribosomal, 16S
Language	English
Publishing date	2022-10-20
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	193085-0
ISSN	1793-6853 ; 0090-2942 ; 0192-415X
ISSN (online)	1793-6853
ISSN	0090-2942 ; 0192-415X
DOI	10.1142/S0192415X22500963
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Article ; Online: Asicimbex Yan, Deng & Wei, a new genus with eight new species and four new combinations (Hymenoptera, Cimbicidae)

Yu-Chen Yan / Wen-Long Yan / Tie-Jun Deng / Mei-Cai Wei

Journal of Hymenoptera Research, Vol 91, Iss , Pp 265-

2022 Volume 308

Abstract: ... Deng & Wei gen. nov., A. concavicaputus Yan & Wei sp. nov., A. dengi Yan & Wei sp. nov., A. koreanus ... Yan & Wei sp. nov., A. lii Yan & Wei sp. nov., A. latistriatus Yan, Deng & Wei sp. nov ... A. maculotegularis Yan & Wei sp. nov., A. nanjingensis Yan & Wei sp. nov. and A. shengi Yan & Wei sp. nov. Four new ...

Abstract	A new genus and eight new species of Cimbicinae from the East Asia are described: Asicimbex Yan, Deng & Wei gen. nov., A. concavicaputus Yan & Wei sp. nov., A. dengi Yan & Wei sp. nov., A. koreanus Yan & Wei sp. nov., A. lii Yan & Wei sp. nov., A. latistriatus Yan, Deng & Wei sp. nov., A. maculotegularis Yan & Wei sp. nov., A. nanjingensis Yan & Wei sp. nov. and A. shengi Yan & Wei sp. nov. Four new combinations are proposed: A. eous (Semenov, 1935) comb. nov., A. elminus (Li & Wu, 2003) comb. nov., A. ulmusvorus (Yang, 1996) comb. nov. and A. malaisei (Gussakovskij, 1947) comb. nov., all from Agenocimbex. The 12 known species of Asicimbex are separated into two species groups. Asicimbex stands between Agenocimbex Rohwer 1910 and Cimbex Olivier 1791. The differences between Asicimbex and Cimbex, Asicimbex and Palaeocimbex are discussed in detail. Descriptions, remarks, illustrations, a key to the known species of Asicimbex and a key to genera of Cimbicinae are provided. A. malaisei is confirmed as a valid species and recorded from China for the first time, with the female described for the first time. The distribution of the genus is also briefly discussed.
Keywords	Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Pensoft Publishers
Document type	Article ; Online
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Article ; Online: Asicimbex Yan, Deng & Wei, a new genus with eight new species and four new combinations (Hymenoptera, Cimbicidae)

Yan, Yu-Chen / Yan, Wen-Long / Deng, Tie-Jun / Wei, Mei-Cai

Journal of Hymenoptera Research. 2022 June 30, v. 91 p.265-308

2022

Abstract: ... Asicimbex Yan, Deng & Wei gen. nov., A. concavicaputus Yan & Wei sp. nov., A. dengi Yan & Wei sp. nov ... A. koreanus Yan & Wei sp. nov., A. lii Yan & Wei sp. nov., A. latistriatus Yan, Deng & Wei sp. nov ... A. maculotegularis Yan & Wei sp. nov., A. nanjingensis Yan & Wei sp. nov. and A. shengi Yan & Wei sp. nov. Four new ...

Abstract	AbstractA new genus and eight new species of Cimbicinae from the East Asia are described: Asicimbex Yan, Deng & Wei gen. nov., A. concavicaputus Yan & Wei sp. nov., A. dengi Yan & Wei sp. nov., A. koreanus Yan & Wei sp. nov., A. lii Yan & Wei sp. nov., A. latistriatus Yan, Deng & Wei sp. nov., A. maculotegularis Yan & Wei sp. nov., A. nanjingensis Yan & Wei sp. nov. and A. shengi Yan & Wei sp. nov. Four new combinations are proposed: A. eous (Semenov, 1935) comb. nov., A. elminus (Li & Wu, 2003) comb. nov., A. ulmusvorus (Yang, 1996) comb. nov. and A. malaisei (Gussakovskij, 1947) comb. nov., all from Agenocimbex. The 12 known species of Asicimbex are separated into two species groups. Asicimbex stands between Agenocimbex Rohwer 1910 and Cimbex Olivier 1791. The differences between Asicimbex and Cimbex, Asicimbex and Palaeocimbex are discussed in detail. Descriptions, remarks, illustrations, a key to the known species of Asicimbex and a key to genera of Cimbicinae are provided. A. malaisei is confirmed as a valid species and recorded from China for the first time, with the female described for the first time. The distribution of the genus is also briefly discussed.
Keywords	Cimbex ; females ; new genus ; new species ; research ; China ; Cimbicinae ; distribution pattern ; Eastern Asia ; Sawflies ; Tenthredinoidea
Language	English
Dates of publication	2022-0630
Size	p. 265-308.
Publishing place	Pensoft Publishers
Document type	Article ; Online
ZDB-ID	2477175-2
ISSN	1314-2607 ; 1070-9428
ISSN (online)	1314-2607
ISSN	1070-9428
DOI	10.3897/jhr.91.83710
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer.

Wang, Ting / Wu, Linguangjin / Wang, Shuyun / Shi, Xiaolan / Liu, Hui / Deng, Wanli

Chinese journal of natural medicines

2023 Volume 21, Issue 5, Page(s) 333–345

Abstract: ... immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ ...

Abstract	The anti-tumor effect of anti-PD-1 antibody has long been shown to be strongly related to the tumor immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ) Decoction can enhance the anti-tumor effect of PD-1 inhibitor therapy. PD-1 inhibitor therapy showed the significant anti-tumor effect in patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC), rather than those with mismatch repair-proficient/microsatellite stable (pMMR/MSS) CRC. Hence, immunofluorescence double-label staining was utilized to explore the difference in the TIME between dMMR/MSI-H and pMMR/MSS CRC patients. Flow cytometry was used to analyze T-lymphocytes in tumors from mice. Western blot was used to measure the expression of PD-L1 protein in mouse tumors. The intestinal mucosal barrier of mice was evaluated by hematoxylin-eosin staining and immunohistochemistry. 16S rRNA-gene sequencing was used to examine the structure of the gut microbiota in mice. Subsequently, Spearmanapos;s correlation analysis was used to analyze the relationship between the gut microbiota and tumor-infiltrating T-lymphocytes. The results showed that dMMR/MSI-H CRC patients had more CD8
MeSH term(s)	Animals ; Mice ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Gastrointestinal Microbiome ; CD8-Positive T-Lymphocytes ; B7-H1 Antigen ; RNA, Ribosomal, 16S ; Colorectal Neoplasms/metabolism ; Colonic Neoplasms ; Tumor Microenvironment
Chemical Substances	Immune Checkpoint Inhibitors ; B7-H1 Antigen ; RNA, Ribosomal, 16S
Language	English
Publishing date	2023-03-03
Publishing country	China
Document type	Journal Article
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(23)60451-0
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Zs.A 6113: Show issues

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Article ; Online: Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer

Wang, Ting / WU, Linguangjin / Wang, Shuyun / SHI, Xiaolan / Liu, Hui / DENG, Wanli

Chinese Journal of Natural Medicines. 2023 May, v. 21, no. 5 p.333-345

2023

Abstract: ... immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ ...

Abstract	The anti-tumor effect of anti-PD-1 antibody has long been shown to be strongly related to the tumor immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ) Decoction can enhance the anti-tumor effect of PD-1 inhibitor therapy. PD-1 inhibitor therapy showed the significant anti-tumor effect in patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC), rather than those with mismatch repair-proficient/microsatellite stable (pMMR/MSS) CRC. Hence, immunofluorescence double-label staining was utilized to explore the difference in the TIME between dMMR/MSI-H and pMMR/MSS CRC patients. Flow cytometry was used to analyze T-lymphocytes in tumors from mice. Western blot was used to measure the expression of PD-L1 protein in mouse tumors. The intestinal mucosal barrier of mice was evaluated by hematoxylin-eosin staining and immunohistochemistry. 16S rRNA-gene sequencing was used to examine the structure of the gut microbiota in mice. Subsequently, Spearmanapos;s correlation analysis was used to analyze the relationship between the gut microbiota and tumor-infiltrating T-lymphocytes. The results showed that dMMR/MSI-H CRC patients had more CD8⁺T cells and higher expression of PD-1 and PD-L1 proteins. In vivo, CWQ enhanced the anti-tumor effect of anti-PD-1 antibody and increased the infiltration of CD8⁺ and PD-1⁺CD8⁺ T cells in tumors. Additionally, the combination of CWQ with anti-PD-1 antibody resulted in lower inflammation in the intestinal mucosa than that induced by anti-PD-1 antibody alone. CWQ and anti-PD-1 antibody co-treatment upregulated PD-L1 protein and reduced the abundance of Bacteroides in the gut microbiota but increased the abundance of Akkermansia,Firmicutes, andActinobacteria. Additionally, the proportion of infiltrated CD8⁺PD-1⁺, CD8⁺, and CD3⁺ T cells were found to be positively correlated with the abundance of Akkermansia. Accordingly, CWQ may modulate the TIME by modifying the gut microbiota and consequently enhance the anti-tumor effect of PD-1 inhibitor therapy.
Keywords	Bacteroides ; T-lymphocytes ; Western blotting ; antibodies ; antineoplastic activity ; colorectal neoplasms ; flow cytometry ; fluorescent antibody technique ; immunohistochemistry ; inflammation ; intestinal microorganisms ; intestinal mucosa ; mice ; therapeutics ; Tumor immune microenvironment ; PD-1 inhibitor therapy ; Gut microbiota ; CD8+ T cells ; Chang Wei Qing
Language	English
Dates of publication	2023-05
Size	p. 333-345.
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(23)60451-0
Database	NAL-Catalogue (AGRICOLA)

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Article: How to Price Ecosystem Water Yield Service and Determine the Amount of Compensation?—The Wei River Basin in China as an Example

Li, Yuanyuan / Ding, Zhenmin / Yao, Shunbo / Xue, Caixia / Deng, Yuanjie / Jia, Lei / Chai, Chaoqing / Zhang, Xiao

Land. 2022 July 21, v. 11, no. 7

2022

Abstract: ... Then, we analyze the spatial and temporal changes of the price and the compensation amounts of water yield service in the Wei ...

Abstract	Determining the price of water yield service is the core of watershed compensation. This is necessary to establish a reasonable and scientific compensation mechanism and achieve the efficient management of water. Unlike previous studies, this study establishes a theoretical model of pricing and a compensation mechanism for achieving a balance between the supply and demand of water yield service. A panel threshold model is used to estimate the production elasticity of water for pricing water yield service. Then, we analyze the spatial and temporal changes of the price and the compensation amounts of water yield service in the Wei River basin, China. The results show that: (1) The water marginal contribution to regional GDP meets the law of diminishing marginal return in the form of the threshold effect. When water input amounts (logarithm) are on both sides of 9.449, the marginal contribution is significantly different. (2) The price of water yield service shows an increasing trend. It was CNY 47.27/m³ in 2015, increasing by 472.94% compared with 2000 (CNY 8.24/m³). The spatial distribution was “high in the southeast and low in the northwest”. (3) Total payment amounts increased from CNY 33.1955 billion in 2000 to CNY 227.1302 billion in 2015 and were mainly distributed in relatively developed areas. The acceptance areas were concentrated in relatively undeveloped areas. Total acceptance amounts increased from CNY 2922.2 million in 2000 to CNY 16,398.6 million in 2015. This study can provide scientific basis for ecological compensation practices and promote high-quality development of the socio-economy of the watershed.
Keywords	ecosystems ; land ; prices ; supply balance ; theoretical models ; threshold models ; water yield ; watersheds ; China
Language	English
Dates of publication	2022-0721
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2682955-1
ISSN	2073-445X
ISSN	2073-445X
DOI	10.3390/land11071118
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Screening for potential quality markers of Callerya nitida var. hirsutissima. Z.Wei based on components profile, pharmacokinetics, and anti-inflammatory study.

Chen, Jingbin / Song, Yonggui / Zhou, Mingyue / Yang, Ming / Zhang, Ling / Naeem, Abid / Li, Zexie / Deng, Yaqiong / Liu, Yali / Ai, Zhifu / Su, Dan

Journal of separation science

2021 Volume 45, Issue 2, Page(s) 638–649

Abstract: Callerya nitida var. hirsutissima. Z.Wei is a classical, traditional Chinese herbal medicine mostly ...

Abstract	Callerya nitida var. hirsutissima. Z.Wei is a classical, traditional Chinese herbal medicine mostly used to treat rheumatoid arthritis. Recent reports suggest that inconsistent and poor-quality control levels have primarily affected the therapeutic efficacy. Therefore, the aim of the current study was to investigate the active chemical ingredients, stability of components in blood, pharmacokinetics, and pharmacodynamics to specify the potential markers for quality control and quality evaluation of Callerya nitida. The active components in vitro and in vivo were obtained by ultra-high-performance liquid chromatography-mass spectrometry. Moreover, the changes of the bioactive components in the blood were monitored over time (0-24 h) in order to identify stable active components. On this basis, the pharmacokinetic characteristics of these ingredients combined with the anti-inflammatory activity were determined to screen out the potential markers for ensuring the quality control of Callerya nitida. The identified four components, such as calycosin, daidzein, formononetin, and 5-hydroxymethylfurfural, have the characteristics of intrinsic components, clearly defined structures, high exposure values, and in vivo stability, which are important for the therapeutic activity of pharmacologically active materials. Therefore, they can be used as potential markers to control the quality levels of Callerya nitida.
MeSH term(s)	Anti-Inflammatory Agents/pharmacology ; Chromatography, High Pressure Liquid/methods ; Drugs, Chinese Herbal/analysis ; Fabaceae ; Medicine, Chinese Traditional
Chemical Substances	Anti-Inflammatory Agents ; Drugs, Chinese Herbal
Language	English
Publishing date	2021-11-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2047990-6
ISSN	1615-9314 ; 1615-9306
ISSN (online)	1615-9314
ISSN	1615-9306
DOI	10.1002/jssc.202100543
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Article ; Online: Network pharmacology and experiments in vivo and in vitro reveal that the Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF) and its active ingredient baicalein ameliorate BLM-induced lung fibrosis in mice via PI3K/Akt signaling pathway.

Shi, Hanlin / Deng, Lingling / Zhou, Yaolong / Yu, Hang / Huang, Xi / Chen, Mengmeng / Lei, Yang / Dong, Jingcheng

Journal of ethnopharmacology

2023 Volume 315, Page(s) 116691

Abstract: Ethnopharmacological relevance: Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF), a classical traditional ...

Abstract	Ethnopharmacological relevance: Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF), a classical traditional Chinese herbal formula consisting of five herbs, is used clinically in China to treat inflammatory lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). Its mechanism for treating asthma and COPD has been reported, however, how it works against IPF remains unclear. Research purpose: Our study aims to observe the therapeutic effect of JWBSYQF on pulmonary fibrosis and further identify the potential active ingredients and molecular pathways. Research methods: In this study, we used a bleomycin-induced mouse model to investigate the therapeutic effect of JWBSYQF on pulmonary fibrosis. To further explore the potential effective ingredients and molecular pathways, we used the network pharmacology approach to construct a drug-ingredient-target network of JWBSYQF. Then, the common target set was established for JWBSYQF, fibroblast, and lung fibrosis. Analyses of the KEGG pathway, GO enrichment, and network topology were performed to identify key biological processes and molecular pathways for the common targets. Finally, a TGF-β-induced NIH/3T3 proliferation and activation model was used to validate the possible active ingredients and signaling pathways. Research results: JWBSYQF reversed BLM-induced balf leukocyte levels, pulmonary inflammatory lesions and fibrotic collagen deposition in mice and reduced the levels of a-SMA, Col1a1 and TGF-β. A total of 86 active ingredients were identified, 12 of which were considered as potential effective ingredients, while only baicalein effectively improved TGF-β-induced proliferation and activation of NIH/3T3. KEGG results showed that PI3K/Akt signaling pathway may be the potential action mechanism, and Western Blot demonstrated that both JWBSYQF and baicalein downregulated the protein levels of p-PI3K and p-Akt. The molecular docking results suggest that baicalein may have a direct effect on the catalytic and regulatory subunits of P13K, which is stronger than direct binding to Aktl. Conclusions: Our study revealed that baicalein may be the material basis for JWBSYQF in the treatment of pulmonary fibrosis, and the PI3K/Akt signaling pathway may be a common pathway of action for JWBSYQF and baicalein.
MeSH term(s)	Animals ; Mice ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Network Pharmacology ; Molecular Docking Simulation ; Idiopathic Pulmonary Fibrosis ; Asthma ; Pulmonary Disease, Chronic Obstructive ; Signal Transduction ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use
Chemical Substances	baicalein (49QAH60606) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Drugs, Chinese Herbal
Language	English
Publishing date	2023-05-27
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116691
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Article ; Online: Establishment of geology-engineering integration model for shale gas of Wei AH platform in Weiyuan Area

Jiang Hai / Xiao Yang / Liu Ziping / Li Zhigang / Deng Xiang / Zou Longqing

E3S Web of Conferences, Vol 329, p

2021 Volume 01041

Abstract: Wei AH platform is a platform composed of 8 horizontal wells in Weiyuan shale gas area. The number ... of geological model, combined with one-dimensional rock mechanics profile, the geomechanical model of Wei AH platform ...

Abstract	Wei AH platform is a platform composed of 8 horizontal wells in Weiyuan shale gas area. The number of faults in the area is small, and natural fractures are locally developed. Therefore, it is necessary to take volume reconstruction as the core mining technology and establish the geology-engineering integration model for the platform according to the geology-engineering integration concept. On the basis of geological model, combined with one-dimensional rock mechanics profile, the geomechanical model of Wei AH platform is established by means of deep diagenetic theory. Based on geological model and geomechanical model, the well trajectory design model, fracturing design model and reservoir numerical simulation model are modeled and optimized respectively. Finally, it can realize the comprehensive application of geophysical, geological, mechanical and seepage data, and complete the mutual call and matching of all kinds of understanding and models.
Keywords	wei ah platform ; shale gas ; geology-engineering integration ; geomechanical model ; fracturing design model ; Environmental sciences ; GE1-350
Subject code	670
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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