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  1. Article: Convalescent plasma from COVID 19 patients enhances intensive care unit survival rate. A preliminary report.

    Cantore, Italo / Valente, Paola

    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

    2020  Volume 59, Issue 5, Page(s) 102848

    MeSH term(s) COVID-19/immunology ; COVID-19/mortality ; COVID-19/therapy ; Humans ; Immunization, Passive ; Intensive Care Units ; Risk Factors ; SARS-CoV-2/physiology
    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country England
    Document type Letter
    ZDB-ID 2046795-3
    ISSN 1878-1683 ; 1473-0502
    ISSN (online) 1878-1683
    ISSN 1473-0502
    DOI 10.1016/j.transci.2020.102848
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    Zs.A 1739: Show issues Location:
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  2. Article ; Online: Ligneous conjunctivitis and use of human plasminogen eyedrops: The Italian experience.

    Sartori, Maria T / Bartuli, Andrea / Siboni, Simona M / Leonardi, Andrea / Valente, Paola / Secci, Jacopo / Cortellessa, Fabiana / Caputo, Roberto

    Haemophilia : the official journal of the World Federation of Hemophilia

    2023  Volume 29, Issue 2, Page(s) 681–684

    MeSH term(s) Humans ; Ophthalmic Solutions/therapeutic use ; Conjunctivitis ; Plasminogen ; Italy/epidemiology
    Chemical Substances Ophthalmic Solutions ; Plasminogen (9001-91-6)
    Language English
    Publishing date 2023-01-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.14745
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  4. Article ; Online: Convalescent plasma from COVID 19 patients enhances intensive care unit survival rate. A preliminary report

    Cantore, Italo / Valente, Paola

    Transfusion and Apheresis Science

    2020  , Page(s) 102848

    Keywords Hematology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2046795-3
    ISSN 1878-1683 ; 1473-0502
    ISSN (online) 1878-1683
    ISSN 1473-0502
    DOI 10.1016/j.transci.2020.102848
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.

    Zwergel, Clemens / Fioravanti, Rossella / Stazi, Giulia / Sarno, Federica / Battistelli, Cecilia / Romanelli, Annalisa / Nebbioso, Angela / Mendes, Eduarda / Paulo, Alexandra / Strippoli, Raffaele / Tripodi, Marco / Pechalrieu, Dany / Arimondo, Paola B / De Luca, Teresa / Del Bufalo, Donatella / Trisciuoglio, Daniela / Altucci, Lucia / Valente, Sergio / Mai, Antonello

    Cancers

    2024  Volume 16, Issue 6

    Abstract: In the original publication [ ... ]. ...

    Abstract In the original publication [...].
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16061230
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  6. Article: Cardiovascular Implications in Idiopathic and Syndromic Obesity in Childhood: An Update.

    Delvecchio, Maurizio / Pastore, Carmela / Valente, Federica / Giordano, Paola

    Frontiers in endocrinology

    2020  Volume 11, Page(s) 330

    Abstract: Childhood obesity is a modern worldwide epidemic with significant burden for health. It is a chronic metabolic disorder associated with multiple cardiovascular risk factors such as dyslipidemia, hypertension, stroke, and insulin resistance. Many obese ... ...

    Abstract Childhood obesity is a modern worldwide epidemic with significant burden for health. It is a chronic metabolic disorder associated with multiple cardiovascular risk factors such as dyslipidemia, hypertension, stroke, and insulin resistance. Many obese adolescents remain obese into adulthood, with increased morbidity and mortality. As childhood obesity is a risk factor for adult obesity, the childhood obesity-related disorders account for an increased risk of cardiovascular consequences in adults, in addition to the effects already exerted by the fat mass in adulthood. Several papers have already described the cardiovascular implications of idiopathic obesity, while few data are available about syndromic obesity, due to the small sample size, not homogeneous phenotypes, and younger age at death. The aim of this mini-review is to give a comprehensive overview on knowledge about cardiovascular implications of idiopathic and syndromic obesity to allow the reader a quick comparison between them. The similarities and differences will be highlighted.
    MeSH term(s) Cardiovascular Diseases/etiology ; Cardiovascular Diseases/pathology ; Child ; Humans ; Pediatric Obesity/classification ; Pediatric Obesity/complications
    Language English
    Publishing date 2020-06-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2020.00330
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  7. Article: Surgical OFF-LOADING of the diabetic foot.

    Dalla Paola, Luca / Carone, Anna / Valente, Marialuisa / Palena, Mariano / Scavone, Giuseppe

    Journal of clinical orthopaedics and trauma

    2021  Volume 16, Page(s) 182–188

    Abstract: Diabetic foot ulcer treatment is a challenge for the healthcare world. Widespread infection and the presence of critical ischemia (especially with end-stage renal disease) can lead to major amputation rather than amenable to conservative treatment. ... ...

    Abstract Diabetic foot ulcer treatment is a challenge for the healthcare world. Widespread infection and the presence of critical ischemia (especially with end-stage renal disease) can lead to major amputation rather than amenable to conservative treatment. Surgical strategies of the diabetic foot have been changing over the past 10 years and are now focused on reconstructive treatment and limb salvage. These goals were achieved, thanks to an evolution of distal revascularization techniques and a distinct approach, which integrates various methods focused on limb salvage. Podoplastic techniques of the diabetic foot are focused on infection clearance, the surgical treatment of corrective deformities, soft tissue coverage and limb ischemia correction along with the management of diabetes and the comorbidities that compromise tissue repair processes. The reconstructive techniques used in diabetic foot treatment owe their effectiveness in part to the results of technological improvements such as the circular external fixator as a tool for stabilization and surgical site protection. In the last decade, many studies have shown that circular external fixation should be considered as the most useful method to protect the reconstructive surgical site in limb salvage of the diabetic foot. The objective of this review is to highlight the role of surgical offloading using circular external fixation as an adjunct to the podoplastic diabetic foot reconstruction procedures.
    Language English
    Publishing date 2021-01-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2596956-0
    ISSN 2213-3445 ; 0976-5662
    ISSN (online) 2213-3445
    ISSN 0976-5662
    DOI 10.1016/j.jcot.2021.01.005
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  8. Article ; Online: Simultaneous transepithelial topographic-guided laser and cross-linking to correct irregular astigmatism in a pediatric patient.

    Buzzonetti, Luca / Petrocelli, Gianni / Petroni, Sergio / Valente, Paola / Iarossi, Giancarlo

    European journal of ophthalmology

    2021  , Page(s) 11206721211046476

    Abstract: Purpose: To evaluate an original approach for treating corneal ectasia and irregular astigmatism secondary to penetrating trauma in a pediatric patient.: Case report: An 11 year old patient had a penetrating trauma in right eye when he was two and ... ...

    Abstract Purpose: To evaluate an original approach for treating corneal ectasia and irregular astigmatism secondary to penetrating trauma in a pediatric patient.
    Case report: An 11 year old patient had a penetrating trauma in right eye when he was two and the refractive error was +1.50 diopters sphere -6.00 diopters cylinder axis 95°. To correct irregular astigmatism, the patient underwent simultaneous transepithelial topographic-guided laser Central Corneal Remodeling (CCR) and Corneal Cross-linking (CXL) in the attempt to regularize corneal ectasia and to improve the quality of vision. Uncorrected and Corrected Distance Visual Acuity were measured using Efficacy and Safety indexes; objective and subjective qualities of vision were evaluated using respectively corneal morphological irregularity index and National Eye Institute Visual Function questionnaires.
    Conclusions: Twelve month follow up suggests that simultaneous CCR and CXL could be effective to improve the quality of vision and to halt the progression of post-traumatic ectasia in pediatric patients.
    Language English
    Publishing date 2021-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721211046476
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    Zs.A 3342: Show issues Location:
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  9. Article: Congenital Malformations of the Eye: A Pictorial Review and Clinico-Radiological Correlations.

    Guarnera, Alessia / Valente, Paola / Pasquini, Luca / Moltoni, Giulia / Randisi, Francesco / Carducci, Chiara / Carboni, Alessia / Lucignani, Giulia / Napolitano, Antonio / Romanzo, Antonino / Longo, Daniela / Gandolfo, Carlo / Rossi-Espagnet, Maria Camilla

    Journal of ophthalmology

    2024  Volume 2024, Page(s) 5993083

    Abstract: Congenital malformations of the eye represent a wide and heterogeneous spectrum of abnormalities that may be part of a complex syndrome or be isolated. Ocular malformation severity depends on the timing of the causative event during eye formation, ... ...

    Abstract Congenital malformations of the eye represent a wide and heterogeneous spectrum of abnormalities that may be part of a complex syndrome or be isolated. Ocular malformation severity depends on the timing of the causative event during eye formation, ranging from the complete absence of the eye if injury occurs during the first weeks of gestation, to subtle abnormalities if the cause occurs later on. Knowledge of ocular malformations is crucial to performing a tailored imaging protocol and correctly reporting imaging findings. Together with the ophthalmologic evaluation, imaging may help frame ocular malformations and identify underlying genetic conditions. The purpose of this pictorial review is to describe the imaging features of the main ocular malformations and the related ophthalmologic findings in order to provide a clinico-radiological overview of these abnormalities to the clinical radiologist. Sight is a crucial sense for children to explore the world and relate with their parents from birth. Vision impairment or even blindness secondary to ocular malformations deeply affects children's growth and quality of life.
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2546525-9
    ISSN 2090-0058 ; 2090-004X
    ISSN (online) 2090-0058
    ISSN 2090-004X
    DOI 10.1155/2024/5993083
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  10. Article ; Online: Simultaneous Labeling of Adipogenic and Osteogenic Differentiating Stem Cells for Live Confocal Analysis.

    Vaghi, Patrizia / Oldani, Amanda / Fulghieri, Paola / Pollara, Lidia / Valente, Enza Maria / Sottile, Virginie

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2566, Page(s) 53–62

    Abstract: Adipocytes and osteoblasts derive from a common mesenchymal progenitor present in a range of connective tissues. Differentiation of the progenitors toward the two cell lineages can be induced in vitro through well-established protocols, and leads to the ... ...

    Abstract Adipocytes and osteoblasts derive from a common mesenchymal progenitor present in a range of connective tissues. Differentiation of the progenitors toward the two cell lineages can be induced in vitro through well-established protocols, and leads to the appearance of lipid-laden adipocytes and osteoblasts embedded in a mineralized matrix. The formation of these two lineages in cell cultures can be monitored using lipophilic dyes such as Oil Red O and substances binding to mineral deposits such as Alizarin Red S, respectively. However, these common staining techniques require cell fixation and are thus incompatible with live analyses. Recently, alternative approaches using vital stains have allowed the dual visualization and fluorescence imaging of adipogenic and osteogenic lineages in live cultures. Here we present the concomitant analysis of cultures containing adipogenic and osteogenic cell types using live staining, combining LipidTox Red and tetracycline with NucRed nuclear counterstain for confocal imaging. This approach can be applied to visualize the kinetics and 3D structure of differentiating mesenchymal cultures over time and highlights the interaction of adipose and mineralized compartments associated with bone marrow stroma.
    MeSH term(s) Adipogenesis ; Cell Differentiation ; Cells, Cultured ; Coloring Agents/metabolism ; Lipids ; Mesenchymal Stem Cells ; Minerals ; Osteogenesis ; Stem Cells ; Tetracyclines/metabolism
    Chemical Substances Coloring Agents ; Lipids ; Minerals ; Tetracyclines
    Language English
    Publishing date 2022-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2675-7_5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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