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Article: Effects of shrink film wrapping and storage temperature on the shelf life and quality of pomegranate fruits cv. Ganesh

Nanda, S / Sudhakar Rao, D.V / Krishnamurthy, S

Postharvest biology and technology. Mar 2001. v. 22 (1)

2001

Abstract: ... 'Ganesh' pomegranates (Punica granatum L.) stored at 8, 15 and 25 degrees C were studied. The shrink ...

Abstract	The effect of individual shrink film wrapping with two polyolefin films (BDF-2001 and D-955) and skin coating with a sucrose polyester (SPE) Semperfresh on the shelf life and quality of soft-seeded 'Ganesh' pomegranates (Punica granatum L.) stored at 8, 15 and 25 degrees C were studied. The shrink-wrapped pomegranates could be stored for 12, 9 and 4 weeks as compared to 8, 6 and 2 weeks by SPE coating at 8, 15 and 25 degrees C respectively, whereas non-wrapped fruits could be kept for 7, 5 and 1 week under similar storage conditions. Peel thickness and freshness and firmness of the fruit were retained and weight loss greatly reduced by shrink wrapping. The weight loss in shrink-wrapped fruits was 1.2-1.3% after 12 weeks of storage at 8 degrees C and 2.2-3.7% after 10 weeks at 15 degrees C. During the same period non-wrapped fruits lost 20.4 and 30.7% at 8 and 15 degrees C, respectively. Changes in acidity, sugars and vitamin C of the shrink-wrapped fruits were lower than that of non-wrapped fruits during 12 weeks of storage at 8 degrees C. Shrink wrapping also reduced the respiration rate of the fruit. No detectable levels of ethylene were produced during storage of pomegranates.
Keywords	pomegranates ; food packaging ; food storage ; temperature ; shelf life ; food quality ; duration ; firmness ; titratable acidity ; brix ; ascorbic acid ; ethylene production ; thickness ; plastic film
Language	English
Dates of publication	2001-03
Size	p. 61-69.
Document type	Article
ZDB-ID	1082798-5
ISSN	0925-5214
ISSN	0925-5214
Database	NAL-Catalogue (AGRICOLA)

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Book: Management of brain metastases

D'Ambrosio, Antonino / Rao, Ganesh

(Neurosurgery clinics of North America ; 22,1)

2011

Author's details	guest ed. Anthony L. D'Ambrosio ; Ganesh Rao
Series title	Neurosurgery clinics of North America ; 22,1
Collection
Language	English
Size	XI, 109 S. : Ill., graph. Darst.
Publisher	Saunders an imprint of Elsevier
Publishing place	Philadelphia, PA
Publishing country	United States
Document type	Book
HBZ-ID	HT016664562
ISBN	978-1-4557-0471-2 ; 1-4557-0471-7
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Retinal Vasoproliferative Tumours in Uveitis.

Ahmed, Arshee S / Dutta Majumder, Parthopratim / Elizabeth, Amala / Rao, Vinita / Ganesh, Sudha / Biswas, Jyotirmay

Ocular immunology and inflammation

2024 , Page(s) 1–5

Abstract: Purpose: To describe a cohort of patients with retinal vasoproliferative tumours (RVPT) seen in the uveitis clinic of a single tertiary eye care institute in India.: Methods: Retrospective Chart Review.: Results: In our study of 17 patients with ... ...

Abstract	Purpose: To describe a cohort of patients with retinal vasoproliferative tumours (RVPT) seen in the uveitis clinic of a single tertiary eye care institute in India. Methods: Retrospective Chart Review. Results: In our study of 17 patients with 18 eyes affected by RVPTs, 94.1% showed unilateral involvement, one patient had bilateral RVPTs, and another had two RVPTs in the same eye. The mean age was 36.3 ± 15.1 years (range: 12-63 years), with a male majority (76.4%). The most common location was inferotemporal quadrant (44.4%). The most common associated uveitic condition was intermediate uveitis (50%). Patients were treated with oral corticosteroid (in 94.1%) and immunosuppressive (35.2%) in addition to transconjunctival cryotherapy (in 52.9%) or laser photocoagulation (in 41.1%). Regression of the RVPT was achieved in all cases except one. Visual acuity at time of detection of RVPT ranged from 6/6 to HM. No significant change was noted in the mean best corrected visual acuity pre and post treatment in the study group. Conclusion: RVPTs, rare peripheral retinal lesions often associated with intermediate uveitis, require early diagnosis with targeted therapy to prevent vision loss and achieve favorable long-term outcomes with rare recurrences.
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1193873-0
ISSN	1744-5078 ; 0927-3948
ISSN (online)	1744-5078
ISSN	0927-3948
DOI	10.1080/09273948.2024.2317418
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Article ; Online: Aspirin and immunotherapy: a Faustian bargain?

Goethe, Eric A / Heimberger, Amy B / Rao, Ganesh

The Journal of clinical investigation

2023 Volume 133, Issue 9

Abstract: Fibrinogen-like protein 1 (FGL1) has been associated with improved survival in hepatocellular carcinoma (HCC). However, recent evidence suggests that FGL1 may bind to surface receptors on lymphocytes and induce immune senescence. In this issue of the JCI, ...

Abstract	Fibrinogen-like protein 1 (FGL1) has been associated with improved survival in hepatocellular carcinoma (HCC). However, recent evidence suggests that FGL1 may bind to surface receptors on lymphocytes and induce immune senescence. In this issue of the JCI, Lin and co-authors show that FGL1 may be acetylated by aspirin and targeted for degradation, which is associated with increased antitumor immunity and improved survival. Similar findings were obtained with inhibitors of sirtuin 2 (SIRT2), a histone deacetylase. These findings expand our current understanding of the role of FGL1 in cancer and provide an impetus for the evaluation of alternative immunotherapy combinations in HCC.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/drug therapy ; Liver Neoplasms/metabolism ; Aspirin/pharmacology ; Aspirin/therapeutic use ; Fibrinogen ; Immunotherapy
Chemical Substances	Aspirin (R16CO5Y76E) ; Fibrinogen (9001-32-5) ; FGL1 protein, human
Language	English
Publishing date	2023-05-01
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	3067-3
ISSN	1558-8238 ; 0021-9738
ISSN (online)	1558-8238
ISSN	0021-9738
DOI	10.1172/JCI169598
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Article ; Online: Aspirin and immunotherapy

Eric A. Goethe / Amy B. Heimberger / Ganesh Rao

The Journal of Clinical Investigation, Vol 133, Iss

a Faustian bargain?

2023 Volume 9

Abstract	Fibrinogen-like protein 1 (FGL1) has been associated with improved survival in hepatocellular carcinoma (HCC). However, recent evidence suggests that FGL1 may bind to surface receptors on lymphocytes and induce immune senescence. In this issue of the JCI, Lin and co-authors show that FGL1 may be acetylated by aspirin and targeted for degradation, which is associated with increased antitumor immunity and improved survival. Similar findings were obtained with inhibitors of sirtuin 2 (SIRT2), a histone deacetylase. These findings expand our current understanding of the role of FGL1 in cancer and provide an impetus for the evaluation of alternative immunotherapy combinations in HCC.
Keywords	Medicine ; R
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	American Society for Clinical Investigation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association of graph-based spatial features with overall survival status of glioblastoma patients.

Lee, Joonsang / Narang, Shivali / Martinez, Juan / Rao, Ganesh / Rao, Arvind

Scientific reports

2023 Volume 13, Issue 1, Page(s) 17046

Abstract: Glioblastoma is the most common malignant brain tumor with less than 15 months median survival. To aid prognosis, there is a need for decision tools that leverage diagnostic modalities such as MRI to inform survival. In this study, we examine higher- ... ...

Abstract	Glioblastoma is the most common malignant brain tumor with less than 15 months median survival. To aid prognosis, there is a need for decision tools that leverage diagnostic modalities such as MRI to inform survival. In this study, we examine higher-order spatial proximity characteristics from habitats and propose two graph-based methods (minimum spanning tree and graph run-length matrix) to characterize spatial heterogeneity over tumor MRI-derived intensity habitats and assess their relationships with overall survival as well as the immune signature status of patients with glioblastoma. A data set of 74 patients was studied based on the availability of post-contrast T1-weighted and T2-weighted fluid attenuated inversion recovery (FLAIR) image data in The Cancer Image Archive (TCIA). We assessed the predictive value of MST- and GRLM-derived features from 2D images for prediction of 12-month survival status and immune signature status of patients with glioblastoma via a receiver operating characteristic curve analysis. For 12-month survival prediction using MST-based method, sensitivity and specificity were 0.82 and 0.79 respectively. For GRLM-based method, sensitivity and specificity were 0.73 and 0.77 respectively. For immune status, sensitivity and specificity were 0.91 and 0.69, respectively, for the GRLM-based method with an immune effector. Our results show that the proposed MST- and GRLM-derived features are predictive of 12-month survival status as well as the immune signature status of patients with glioblastoma. To our knowledge, this is the first application of MST- and GRLM-based proximity analyses for the study of radiologically-defined tumor habitats in glioblastoma.
MeSH term(s)	Humans ; Glioblastoma ; Brain Neoplasms ; Magnetic Resonance Imaging/methods ; Prognosis ; ROC Curve ; Retrospective Studies
Language	English
Publishing date	2023-10-09
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-44353-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Intraoperative MRI and Maximizing Extent of Resection.

Rao, Ganesh

Neurosurgery clinics of North America

2017 Volume 28, Issue 4, Page(s) 477–485

Abstract: Intraoperative MRI (iMRI) is a neurosurgical adjunct used to maximize the removal of glioma, the most common primary brain tumor. Increased extent of resection of gliomas has been shown to correlate with longer survival times. iMRI units are variable in ... ...

Abstract	Intraoperative MRI (iMRI) is a neurosurgical adjunct used to maximize the removal of glioma, the most common primary brain tumor. Increased extent of resection of gliomas has been shown to correlate with longer survival times. iMRI units are variable in design and magnet strength, which can affect patient selection and image quality. Multiple studies have shown that surgical resection of gliomas using iMRI results in increased extent of resection and survival time. Level II evidence supports the use of iMRI in the surgical treatment of glioma.
Language	English
Publishing date	2017-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1196855-2
ISSN	1558-1349 ; 1042-3680
ISSN (online)	1558-1349
ISSN	1042-3680
DOI	10.1016/j.nec.2017.05.003
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Article ; Online: Comparative evaluation of the antibacterial activity of red diode laser therapy and 0.2% chlorhexidine against

Sengupta, Soumee / Ganesh, S / Meenakshi, S / Bettahalli, Avinash Singh / Rao, Raghavendra M / Swamy, K N Raghavendra

Journal of Indian Prosthodontic Society

2023 Volume 23, Issue 1, Page(s) 12–20

Abstract: Aims: The intraoral microbiota has a high potential to undergo dysbiosis, causing inflammatory changes with respect to the tissues surrounding either a natural tooth or an implant. Thus, the longevity of implant prosthesis depends on a thorough implant ... ...

Abstract	Aims: The intraoral microbiota has a high potential to undergo dysbiosis, causing inflammatory changes with respect to the tissues surrounding either a natural tooth or an implant. Thus, the longevity of implant prosthesis depends on a thorough implant decontamination protocol. Among all the techniques available for doing so, laser is garnering increasing popularity, owing to minimal bleeding, high efficiency, and faster healing. However, limited literature exists regarding the superiority of lasers over chlorhexidine (CHX), the indisputable gold standard antibacterial chemical agent. The aim of this study was to compare the percentage of bacterial reduction of Aggregatibacter actinomycetemcomitans from implant healing abutments post red diode laser therapy versus 0.2% CHX treatment. Settings and design: The current study had an ex vivo, observational, case-control design. Materials and methods: Patients reporting for the second stage of the implant surgery were taken as the source of data and the healing abutments, the clinical samples. Eleven patients were chosen with one intraoral implant serving as the test site for laser treatment and another, the control site for CHX treatment. Microbiological analysis was performed via quantitative real time polymerase chain reaction to compare the bacterial reduction percentage after each treatment. Statistical analysis used: Repeated measures ANOVA and independent sample t test were used. Results: The mean bacterial viability of the test group (laser) was 1.2%-1.6%, and 0.6%-1.4% for the control group (CHX). The former caused a mean bacterial reduction of 96.1% while the latter, 96.3%. Both the treatments caused a highly statistically significant reduction of viable bacterial counts (P = 0.001). However, when compared, there was no statistically significant difference in the bacterial reduction, when compared in between the two (P = 0.902). Conclusion: Laser treatment is at par with chemical implant surface decontamination. It can help bypass the complications of CHX and revolutionize the protocols for implant surface decontamination.
MeSH term(s)	Humans ; Chlorhexidine/pharmacology ; Chlorhexidine/therapeutic use ; Aggregatibacter actinomycetemcomitans ; Dental Implants/microbiology ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Laser Therapy ; Lasers, Semiconductor/therapeutic use
Chemical Substances	Chlorhexidine (R4KO0DY52L) ; Dental Implants ; Anti-Bacterial Agents
Language	English
Publishing date	2023-01-02
Publishing country	India
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1998-4057
ISSN (online)	1998-4057
DOI	10.4103/jips.jips_158_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Assessing the clinical efficacy of low-volume therapeutic plasma exchange in achieving recovery from acute liver failure induced by yellow phosphorous poisoning.

Ninan, Ancy / Mohan, Ganesh / Shanbhag, Vishal / Chenna, Deepika / Shastry, Shamee / Rao, Shwethapriya

Journal of clinical apheresis

2024 Volume 39, Issue 3, Page(s) e22110

Abstract: Background: Acute liver failure (ALF) following yellow phosphorous (YP) ingestion is similar to acetaminophen-induced ALF and it has become a public concern in our region. This study assessed low volume therapeutic plasma exchange (LV-TPE) efficacy in ... ...

Abstract	Background: Acute liver failure (ALF) following yellow phosphorous (YP) ingestion is similar to acetaminophen-induced ALF and it has become a public concern in our region. This study assessed low volume therapeutic plasma exchange (LV-TPE) efficacy in improving the transplant free survival in YP poisoning. Methods: Adult patients with toxicology reports of YP and ALF requiring critical care were included in the study. LV-TPE was planned for three consecutive days and three more if required. Performed 1.3 to 1.5 plasma volume replacing with 0.9% normal saline, 5% human albumin solution, and fresh frozen plasma based on ASFA 2019 criteria. MELD score, laboratory parameters, LV-TPE details were captured. The study end point was clinical outcome of the patients. Results: Among 36 patients, 19 underwent LV-TPE and 17 opted out of LV-TPE and they were included as a control arm. The MELD score was 32.64 ± 8.05 and 37.83 ± 9.37 in both groups. There were 13 survivors in LV-TPE group leading to a 68.42% reduction in mortality. The coagulation and biochemical parameters showed a significant percentage change after LV-TPE. Refractory shock, delay in initiating procedure and acidosis were independent predictors of mortality. Conclusion: A well-timed LV-TPE improves the survival of patients with ALF due to YP poisoning.
MeSH term(s)	Adult ; Humans ; Plasma Exchange/methods ; Liver Failure, Acute/therapy ; Treatment Outcome
Language	English
Publishing date	2024-04-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	604912-6
ISSN	1098-1101 ; 0733-2459
ISSN (online)	1098-1101
ISSN	0733-2459
DOI	10.1002/jca.22110
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Article ; Online: The Role of Hyperexcitability in Gliomagenesis

Eric A. Goethe / Benjamin Deneen / Jeffrey Noebels / Ganesh Rao

International Journal of Molecular Sciences, Vol 24, Iss 1, p

2023 Volume 749

Abstract: Glioblastoma is the most common malignant primary brain tumor. Recent studies have demonstrated that excitatory or activity-dependent signaling—both synaptic and non-synaptic—contribute to the progression of glioblastoma. Glutamatergic receptors may be ... ...

Abstract	Glioblastoma is the most common malignant primary brain tumor. Recent studies have demonstrated that excitatory or activity-dependent signaling—both synaptic and non-synaptic—contribute to the progression of glioblastoma. Glutamatergic receptors may be stimulated via neuron–tumor synapses or release of glutamate by the tumor itself. Ion currents generated by these receptors directly alter the structure of membrane adhesion molecules and cytoskeletal proteins to promote migratory behavior. Additionally, the hyperexcitable milieu surrounding glioma increases the rate at which tumor cells proliferate and drive recurrent disease. Inhibition of excitatory signaling has shown to effectively reduce its pro-migratory and -proliferative effects.
Keywords	glioma ; glioblastoma ; tumor microenvironment ; hyperexcitability ; neuroglial synapse ; glutamate ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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