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  1. Book ; Thesis: Der essentielle Tremor

    Kronenbürger, Martin

    eine multisymptomatische Erkrankung

    2011  

    Author's details vorgelegt von Martin Kronenbuerger
    Language German
    Size Getr. Zählung : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Habil-Schr., 2011
    HBZ-ID HT016863044
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; Thesis: Riechen und Schmecken beim Blepharospasmus

    Gamain, Julie Amélie Guillemette [Verfasser] / Kronenbürger, Martin [Akademischer Betreuer] / Kronenbürger, Martin [Gutachter] / Hähner, Antje [Gutachter]

    2023  

    Author's details Julie Gamain ; Gutachter: Martin Kronenbürger, Antje Hähner ; Betreuer: Martin Kronenbürger
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität Greifswald
    Publishing place Greifswald
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Book ; Thesis: Die Hochfrequenzstimulation im Thalamus zur Behandlung des therapieresistenten Tremors

    Kronenbürger, Martin

    1999  

    Author's details vorgelegt von Martin Kronenbürger
    Language German
    Size 132 Bl. : Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2000
    HBZ-ID HT012863325
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online ; Thesis: Riechen und Schmecken bei der zervikalen Dystonie

    Herr, Thorsten [Verfasser] / Kronenbürger, Martin [Akademischer Betreuer] / Kronenbürger, Martin [Gutachter] / Freiherr, Jessica [Gutachter]

    2022  

    Author's details Thorsten Herr ; Gutachter: Martin Kronenbürger, Jessica Freiherr ; Betreuer: Martin Kronenbürger
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität Greifswald
    Publishing place Greifswald
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article ; Online: Pearls & Oy-sters: Positional vertigo and vertical nystagmus in medulloblastoma: A picture is worth a thousand words.

    Kronenbuerger, Martin / Olivi, Alessandro / Zee, David S

    Neurology

    2018  Volume 90, Issue 4, Page(s) e352–e354

    MeSH term(s) Adult ; Brain/diagnostic imaging ; Cerebellar Neoplasms/complications ; Cerebellar Neoplasms/diagnostic imaging ; Cerebellar Neoplasms/therapy ; Diagnosis, Differential ; Female ; Humans ; Medulloblastoma/complications ; Medulloblastoma/diagnostic imaging ; Medulloblastoma/therapy ; Nystagmus, Pathologic/complications ; Nystagmus, Pathologic/diagnostic imaging ; Nystagmus, Pathologic/therapy ; Vertigo/complications ; Vertigo/diagnostic imaging ; Vertigo/therapy
    Language English
    Publishing date 2018-01-21
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000004866
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Treatment Realities of Headache Disorders in Rural Germany by the Example of the Region of Western Pomerania.

    Thiele, Anne / Strauß, Sebastian / Angermaier, Anselm / Klehr, Lara / Bartsch, Luise / Kronenbuerger, Martin / Schmidt, Sein / Fleischmann, Robert

    Brain sciences

    2021  Volume 11, Issue 7

    Abstract: 1) Background: Headache disorders are among the most disabling medical conditions but the supply with experienced providers is outpaced by the demand for service. It is unclear to what extent particularly patients in rural regions are affected by ... ...

    Abstract (1) Background: Headache disorders are among the most disabling medical conditions but the supply with experienced providers is outpaced by the demand for service. It is unclear to what extent particularly patients in rural regions are affected by limited access to comprehensive care. Furthermore, it is unknown what role general practitioners (GPs) play in headache care. (2) Methods: First-time consultations to a specialised headache clinic at a tertiary care centre were asked to participate. Their socio-demographic background, general and headache-specific medical history, disability and quality of life (QoL) were assessed. Additionally, 176 GPs in neighbouring districts were contacted regarding headache management. (3) Results: We assessed 162 patients with first-time consultations (age 46.1 ± 17.0 years, 78.1% female), who suffered from migraine (72%), tension type, cluster and secondary headaches (each 5-10%). About 50% of patients received a new headache-diagnosis and 60% had treatment inconsistent with national guidelines. QoL was significantly worse in all domains compared to the general population. About 75% of GPs see headache patients at least several times per week, and mostly treat them by themself. (4) Conclusions: More than every second headache patient was neither correctly diagnosed nor received guideline adherent treatment. Headache-related disability is inferior to what is expected from previous studies. Access to specialised health care is more limited in rural than in urban regions in Germany and GPs request more training.
    Language English
    Publishing date 2021-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci11070839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Preventive treatment with CGRP monoclonal antibodies restores brain stem habituation deficits and excitability to painful stimuli in migraine: results from a prospective case-control study.

    Thiele, Anne / Klehr, Lara / Strauß, Sebastian / Angermaier, Anselm / Schminke, Ulf / Kronenbuerger, Martin / Naegel, Steffen / Fleischmann, Robert

    The journal of headache and pain

    2021  Volume 22, Issue 1, Page(s) 149

    Abstract: Background & objectives: Calcitonin gene-related peptide ligand/receptor (CGRP) antibodies effectively reduce headache frequency in migraine. It is understood that they act peripherally, which raises the question whether treatment merely interferes with ...

    Abstract Background & objectives: Calcitonin gene-related peptide ligand/receptor (CGRP) antibodies effectively reduce headache frequency in migraine. It is understood that they act peripherally, which raises the question whether treatment merely interferes with the last stage of headache generation or, alternatively, causes secondary adaptations in the central nervous system and might thus possess disease modifying potential. This study addresses this question by investigating the nociceptive blink reflex (nBR), which is closely tied to central disease activity, before and after treatment with CGRP antibodies.
    Methods: We enrolled 22 patients suffering episodic migraine (21 female, 46.2 ± 13.8 years of age) and 22 age-/gender-matched controls. Patients received assessments of the nBR (R2 component, 10 trials, 6 stimuli/trial) before (V0) and three months (V3) after treatment with CGRP antibodies started, controls were assessed once. The R2 area (R2a) and habituation (R2h; gradient of R2a against stimulus order) of the stimulated/non-stimulated side (_s/_ns) following repeated supraorbital stimulation provide a direct readout of brainstem excitability and habituation as key mechanisms in migraine.
    Results: All patients showed a substantial reduction of headache days/month (V0: 12.4±3.3, V3: 6.6 ± 4.9). R2a_s (F
    Discussion: We provide evidence that three months of treatment with CGRP antibodies restores brain stem responses to painful stimuli and thus might be considered disease modifying. The nociceptive blink reflex may provide a biomarker to monitor central disease activity. Future studies should evaluate the blink reflex as a clinical biomarker to predict treatment response at baseline and to establish the risk of relapse after treatment discontinuation.
    Trial registration: This trial was prospectively registered at clinicaltrials.gov (ID: NCT04019496, date of registration: July 15, 2019).
    MeSH term(s) Adult ; Antibodies, Monoclonal/therapeutic use ; Brain Stem ; Calcitonin Gene-Related Peptide ; Case-Control Studies ; Female ; Habituation, Psychophysiologic ; Humans ; Male ; Middle Aged ; Migraine Disorders/drug therapy ; Prospective Studies
    Chemical Substances Antibodies, Monoclonal ; Calcitonin Gene-Related Peptide (JHB2QIZ69Z)
    Language English
    Publishing date 2021-12-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2036768-5
    ISSN 1129-2377 ; 1129-2369
    ISSN (online) 1129-2377
    ISSN 1129-2369
    DOI 10.1186/s10194-021-01364-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies.

    Ross, Christopher A / Kronenbuerger, Martin / Duan, Wenzhen / Margolis, Russell L

    Handbook of clinical neurology

    2017  Volume 144, Page(s) 15–28

    Abstract: The CAG repeat expansion mutation that causes Huntington Disease (HD) was discovered more than 20 years ago, yet no treatment has yet been developed to stop the relentless course of the disease. Nonetheless, substantial progress has been made in ... ...

    Abstract The CAG repeat expansion mutation that causes Huntington Disease (HD) was discovered more than 20 years ago, yet no treatment has yet been developed to stop the relentless course of the disease. Nonetheless, substantial progress has been made in understanding HD pathogenesis. We review insights that have been gleaned from HD genetics, metabolism, and pathology; HD mouse and cell models; the structure, function and post-translational modification of normal and mutant huntingtin (htt) protein; gene expression profiles in HD cells and tissue; the neurotoxicy of mutant htt RNA; and the expression of an antisense transcript from the HD locus. We conclude that rationale therapeutics for HD is within sight, though many questions remain to be answered.
    MeSH term(s) Animals ; Disease Models, Animal ; Huntingtin Protein/genetics ; Huntington Disease/genetics ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Mice ; Mutation/genetics ; Protein Processing, Post-Translational/genetics ; Trinucleotide Repeat Expansion/genetics
    Chemical Substances Huntingtin Protein
    Language English
    Publishing date 2017-08-24
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-12-801893-4.00002-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Successful treatment of choreo-athetotic movements in a patient with an EEF1A2 gene variant.

    Lance, Eboni I / Kronenbuerger, Martin / Cohen, Julie S / Furmanski, Orion / Singer, Harvey S / Fatemi, Ali

    SAGE open medical case reports

    2018  Volume 6, Page(s) 2050313X18807622

    Abstract: Pathogenic variants ... ...

    Abstract Pathogenic variants in
    Language English
    Publishing date 2018-10-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X18807622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction to: Smell and taste in cervical dystonia.

    Herr, Thorsten / Hummel, Thomas / Vollmer, Marcus / Willert, Carsten / Veit, Birgitt / Gamain, Julie / Fleischmann, Robert / Lehnert, Bernhard / Mueller, Jan-Uwe / Stenner, Andrea / Kronenbuerger, Martin

    Journal of neural transmission (Vienna, Austria : 1996)

    2021  Volume 128, Issue 6, Page(s) 873

    Language English
    Publishing date 2021-05-06
    Publishing country Austria
    Document type Published Erratum
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-021-02340-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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