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  1. Book: Omega-3 fatty acids and cardiovascular diseases

    Schacky, Clemens von

    (UNI-MED science)

    2010  

    Author's details [Clemens von Schacky. In collab. with ...]
    Series title UNI-MED science
    Keywords Koronare Herzkrankheit ; Lipidstoffwechsel ; Omega-3-Fettsäuren
    Subject Polyenfettsäuren ; Fettsäuren ; Fischölfettsäuren ; N-3-Fettsäuren ; Fettstoffwechsel ; Lipide ; Herzkranzgefäßleiden ; Koronararterie ; Herzkranzgefäßkrankheit ; Coronary artery disease
    Subject code 616.123071
    Language English
    Size 79 S. : Ill., graph. Darst., 25 cm
    Edition 1. Aufl.
    Publisher UNI-MED-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT016753704
    ISBN 978-3-8374-1213-0 ; 978-1-84815-156-7 ; 3-8374-1213-X ; 1-84815-156-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 1151 order for loan Magazin

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  2. Article ; Online: Importance of EPA and DHA Blood Levels in Brain Structure and Function.

    von Schacky, Clemens

    Nutrients

    2021  Volume 13, Issue 4

    Abstract: Brain structure and function depend on a constant and sufficient supply with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by blood. Blood levels of EPA and DHA reflect dietary intake and other variables and are preferably assessed as ... ...

    Abstract Brain structure and function depend on a constant and sufficient supply with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by blood. Blood levels of EPA and DHA reflect dietary intake and other variables and are preferably assessed as percentage in erythrocytes with a well-documented and standardized analytical method (HS-Omega-3 Index
    MeSH term(s) Brain/anatomy & histology ; Brain/drug effects ; Brain/physiology ; Docosahexaenoic Acids/administration & dosage ; Docosahexaenoic Acids/blood ; Docosahexaenoic Acids/pharmacology ; Eicosapentaenoic Acid/administration & dosage ; Eicosapentaenoic Acid/blood ; Eicosapentaenoic Acid/pharmacology ; Humans
    Chemical Substances Docosahexaenoic Acids (25167-62-8) ; Eicosapentaenoic Acid (AAN7QOV9EA)
    Language English
    Publishing date 2021-03-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu13041074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: How to prevent cardiovascular events from recurring.

    Lechner, Katharina / von Schacky, Clemens

    European journal of preventive cardiology

    2021  Volume 29, Issue 10, Page(s) e295–e297

    MeSH term(s) Humans ; Causality ; Cardiovascular Diseases
    Language English
    Publishing date 2021-02-19
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1177/2047487320909943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4686: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Der Omega-3-Index in der Schwangerschaft - warum der Status entscheidet

    von Schacky, Clemens

    OM & Ernährung : Sonderheft

    2021  Volume 21, Issue "Fertilität und Schwangerschaft", Page(s) 4

    Language German
    Document type Article
    ZDB-ID 2901826-2
    ISSN 1660-8631
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Omega-3 Fatty Acids in Pregnancy-The Case for a Target Omega-3 Index.

    von Schacky, Clemens

    Nutrients

    2020  Volume 12, Issue 4

    Abstract: Scientific societies recommend increasing intake of docosahexaenoic acid (DHA) by 200 mg/day during pregnancy. However, individually, clinical events correlate quite strongly with levels of eicosapentaenoic acid (EPA) and DHA in blood, but these levels ... ...

    Abstract Scientific societies recommend increasing intake of docosahexaenoic acid (DHA) by 200 mg/day during pregnancy. However, individually, clinical events correlate quite strongly with levels of eicosapentaenoic acid (EPA) and DHA in blood, but these levels poorly correlate with amounts ingested. EPA and DHA in erythrocytes (Omega-3 Index) have a low biologic variability. If analyzed with a standardized analytical procedure (HS-Omega-3 Index
    MeSH term(s) Dietary Supplements ; Fatty Acids, Omega-3/administration & dosage ; Fatty Acids, Omega-3/adverse effects ; Fatty Acids, Omega-3/blood ; Fatty Acids, Omega-3/therapeutic use ; Female ; Germany ; Humans ; Lactation ; Pregnancy/physiology ; Premature Birth ; Prenatal Care
    Chemical Substances Fatty Acids, Omega-3
    Language English
    Publishing date 2020-03-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12040898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Omega-3 index in 2018/19.

    von Schacky, Clemens

    The Proceedings of the Nutrition Society

    2020  , Page(s) 1–7

    Abstract: The omega-3 index, the percentage of EPA plus DHA in erythrocytes (measured by standardised analysis), represents a human body's status in EPA and DHA. An omega-3 index is measured in many laboratories around the world; however, even small differences in ...

    Abstract The omega-3 index, the percentage of EPA plus DHA in erythrocytes (measured by standardised analysis), represents a human body's status in EPA and DHA. An omega-3 index is measured in many laboratories around the world; however, even small differences in analytical methods entail large differences in results. Nevertheless, results are frequently related to the target range of 8-11 %, defined for the original and scientifically validated method (HS-Omega-3 Index®), raising ethical issues, and calling for standardisation. No human subject has an omega-3 index <2 %, indicating a vital minimum. Thus, the absence of EPA and DHA cannot be tested against presence. Moreover, clinical events correlate with levels, less with the dose of EPA and DHA, and the bioavailability of EPA and DHA varies inter-individually. Therefore, the effects of EPA and DHA are difficult to demonstrate using typical drug trial methods. Recent epidemiologic data further support the relevance of the omega-3 index in the cardiovascular field, since total mortality, cardiovascular mortality, cardiovascular events such as myocardial infarction or stroke, or blood pressure all correlate inversely with the omega-3 index. The omega-3 index directly correlates with complex brain functions. Compiling recent data supports the target range for the omega-3 index of 8-11 % in pregnancy. Many other potential applications have emerged. Some, but not all health issues mentioned have already been demonstrated to be improved by increasing intake of EPA and DHA. Increasing the omega-3 index into the target range of 8-11 % with individualised doses of toxin-free sources for EPA and DHA is tolerable and safe.
    Language English
    Publishing date 2020-05-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 391142-1
    ISSN 1475-2719 ; 0029-6651
    ISSN (online) 1475-2719
    ISSN 0029-6651
    DOI 10.1017/S0029665120006989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Omega-3 supplementation and cardiovascular disease.

    Tveiten, Dag / Norseth, Jon / Von Schacky, Clemens

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2021  Volume 141, Issue 10

    Title translation Omega-3-tilskudd og hjerte- og karsykdommer.
    MeSH term(s) Cardiovascular Diseases/prevention & control ; Dietary Supplements ; Humans
    Language Norwegian
    Publishing date 2021-06-28
    Publishing country Norway
    Document type Journal Article ; Comment
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.21.0466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Zs.MO 546: Show issues

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  8. Article: Rebuttal to Aung et al, "Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77 917 Individuals".

    von Schacky, Clemens

    Alternative therapies in health and medicine

    2018  Volume 24, Issue 2, Page(s) 8–9

    Abstract: No Abstract Available. ...

    Abstract No Abstract Available.
    MeSH term(s) Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Dietary Supplements ; Fatty Acids, Omega-3/therapeutic use ; Humans ; Meta-Analysis as Topic
    Chemical Substances Fatty Acids, Omega-3
    Language English
    Publishing date 2018-05-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4504: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article: ω-3-Fettsäuren – gesundheitliche Effekte und Diagnose des Mangels

    von Schacky, Prof. Dr. med. Clemens

    Zeitschrift für Orthomolekulare Medizin

    2021  Volume 19, Issue 02, Page(s) 4–6

    Abstract: ... von Schacky. ... Fettsäuren und die Effekte der maritimen Fettsäuren sprach Herausgeber Uwe Gröber mit Professor Dr. Clemens ...

    Abstract Ein Mangel an ω-3-Fettsäuren ist weltweit verbreitet. Ursache sind u. a. ein zu geringer Fischverzehr sowie rückläufige Gehalte von Eicosapentaensäure (EPA) und Docosahexaensäure (DHA) in Zuchtlachs. Es deutet sich an, dass die Mortalität an COVID-19 durch die Gabe von EPA und DHA reduziert werden kann. Zudem können diese Fettsäuren den mit der Alterung verbundenen Abbau von Muskeln und Gehirn verlangsamen und sich günstig auf Entzündungen auswirken. Über die Bestimmung des Versorgungsstatus mit ω-3-Fettsäuren und die Effekte der maritimen Fettsäuren sprach Herausgeber Uwe Gröber mit Professor Dr. Clemens von Schacky.
    Keywords ω-3-Fettsäuren ; Mangel ; ω-3-Index ; Ernährung ; COVID-19 ; Cytokinsturm ; Sarkopenie ; Entzündungen ; Vitamin-K-Antagonisten ; ASS
    Language German
    Publishing date 2021-06-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2399341-8
    ISSN 1864-2470 ; 1611-5562
    ISSN (online) 1864-2470
    ISSN 1611-5562
    DOI 10.1055/a-1484-8059
    Database Thieme publisher's database

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  10. Article: Omega-3 Fatty Acids in Pregnancy—The Case for a Target Omega-3 Index

    von Schacky, Clemens

    Nutrients. 2020 Mar. 26, v. 12, no. 4

    2020  

    Abstract: Scientific societies recommend increasing intake of docosahexaenoic acid (DHA) by 200 mg/day during pregnancy. However, individually, clinical events correlate quite strongly with levels of eicosapentaenoic acid (EPA) and DHA in blood, but these levels ... ...

    Abstract Scientific societies recommend increasing intake of docosahexaenoic acid (DHA) by 200 mg/day during pregnancy. However, individually, clinical events correlate quite strongly with levels of eicosapentaenoic acid (EPA) and DHA in blood, but these levels poorly correlate with amounts ingested. EPA and DHA in erythrocytes (Omega-3 Index) have a low biologic variability. If analyzed with a standardized analytical procedure (HS-Omega-3 Index®), analytical variability is low. Thus, the largest database of any fatty acid analytical method was provided. Pregnant women in Germany had a mean Omega-3 Index below the target range suggested for cardiovascular disease of 8–11%, with large interindividual variation, and quite independent of supplementation with EPA and DHA. In Germany, premature birth is a major health issue. Premature birth and other health issues of pregnant women and their offspring correlate with levels of EPA and DHA in blood and can be reduced by increasing intake of EPA and DHA, according to individual trials and pertinent meta-analyses. Very high intake or levels of EPA and DHA may also produce health issues, like bleeding, prolonged gestation, or even premature birth. While direct evidence remains to be generated, evidence from various scientific approaches supports that the target range for the Omega-3 Index of 8–11% might also pertain to pregnancy and lactation.
    Keywords analytical methods ; cardiovascular diseases ; databases ; docosahexaenoic acid ; eicosapentaenoic acid ; erythrocytes ; hemorrhage ; lactation ; meta-analysis ; nutrients ; omega-3 fatty acids ; pregnancy ; pregnant women ; premature birth ; progeny ; society ; variability ; Germany
    Language English
    Dates of publication 2020-0326
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-light
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12040898
    Database NAL-Catalogue (AGRICOLA)

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