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  1. Article ; Online: A heat transfer model for liquid film boiling on micro-structured surfaces.

    Li, Pengkun / Zou, Qifan / Liu, Xiuliang / Yang, Ronggui

    National science review

    2024  Volume 11, Issue 5, Page(s) nwae090

    Abstract: High heat transfer coefficient (HTC) and critical heat flux (CHF) are achieved in liquid film boiling by coupling vibrant vapor bubbles with a capillary liquid film, which has thus received increased interest for thermal management of high-power ... ...

    Abstract High heat transfer coefficient (HTC) and critical heat flux (CHF) are achieved in liquid film boiling by coupling vibrant vapor bubbles with a capillary liquid film, which has thus received increased interest for thermal management of high-power electronics. Although some experimental progress has been made, a high-fidelity heat transfer model for liquid film boiling is lacking. This work develops a thermal-hydrodynamic model by considering both evaporation atop the wick and nucleate boiling inside the wick to simultaneously predict the HTC and CHF. Nucleate boiling is modeled with microlayer evaporation theory, where a unified scaling factor is defined to characterize the change of microlayer area with heat flux. The scaling factor
    Language English
    Publishing date 2024-03-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 2745465-4
    ISSN 2053-714X ; 2053-714X
    ISSN (online) 2053-714X
    ISSN 2053-714X
    DOI 10.1093/nsr/nwae090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Cytosolic Acetoacetyl-CoA Thiolase TaAACT1 Is Required for Defense against

    Xiong, Feng / Zhu, Xiuliang / Luo, Changsha / Liu, Zhixiang / Zhang, Zengyan

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: ... Fusarium ... ...

    Abstract Fusarium pseudograminearum
    MeSH term(s) Fusarium/genetics ; Triticum/genetics ; Plant Diseases/genetics ; Genotype
    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Cytosolic Acetoacetyl-CoA Thiolase TaAACT1 Is Required for Defense against Fusarium pseudograminearum in Wheat

    Feng Xiong / Xiuliang Zhu / Changsha Luo / Zhixiang Liu / Zengyan Zhang

    International Journal of Molecular Sciences, Vol 24, Iss 6165, p

    2023  Volume 6165

    Abstract: Fusarium pseudograminearum is a major pathogen for the destructive disease Fusarium crown rot (FCR) of wheat ( Triticum aestivum ). The cytosolic Acetoacetyl-CoA thiolase II (AACT) is the first catalytic enzyme in the mevalonate pathway that ... ...

    Abstract Fusarium pseudograminearum is a major pathogen for the destructive disease Fusarium crown rot (FCR) of wheat ( Triticum aestivum ). The cytosolic Acetoacetyl-CoA thiolase II (AACT) is the first catalytic enzyme in the mevalonate pathway that biosynthesizes isoprenoids in plants. However, there has been no investigation of wheat cytosolic AACT genes in defense against pathogens including Fusarium pseudograminearum . Herein, we identified a cytosolic AACT-encoding gene from wheat, named TaAACT1 , and demonstrated its positively regulatory role in the wheat defense response to F. pseudograminearum . One haplotype of TaAACT1 in analyzed wheat genotypes was associated with wheat resistance to FCR. The TaAACT1 transcript level was elevated after F. pseudograminearum infection, and was higher in FCR-resistant wheat genotypes than in susceptible wheat genotypes. Functional analysis indicated that knock down of TaAACT1 impaired resistance against F. pseudograminearum and reduced the expression of downstream defense genes in wheat. TaAACT1 protein was verified to localize in the cytosol of wheat cells. TaAACT1 and its modulated defense genes were rapidly responsive to exogenous jasmonate treatment. Collectively, TaAACT1 contributes to resistance to F. pseudograminearum through upregulating the expression of defense genes in wheat. This study sheds new light on the molecular mechanisms underlying wheat defense against FCR.
    Keywords cytosolic acetoacetyl-CoA thiolase ; Fusarium pseudograminearum ; jasmonate ; plant defense ; wheat ( Triticum aestivum ) ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Impact of diltiazem/beprost on exercise endurance in healthy young males after high altitude exposure

    LI Xiangjun / WANG Xiuliang / LIU Fangzhou / ZHOU Liang / ZHANG Lunwei

    陆军军医大学学报, Vol 45, Iss 6, Pp 480-

    2023  Volume 485

    Abstract: Objective To investigate the efficacy and safety of single or combined use of diltiazem and beprost on exercise endurance improvement after high altitude exposure in healthy young males. Methods A total of 200 non-Tibet health young men who have ... ...

    Abstract Objective To investigate the efficacy and safety of single or combined use of diltiazem and beprost on exercise endurance improvement after high altitude exposure in healthy young males. Methods A total of 200 non-Tibet health young men who have inhabited in plain areas for generations and were transferred from plain to plateau (2 815 m) from July 2017 to August 2020 were recruited in the study. The participants were randomly assigned in group A (90 mg diltiazem sustained-release capsule placebo once a day and 40 μg beraprost placebo 3 times a day), B (90 mg diltiazem sustained-release capsule placebo once a day and 40 μg beraprost 3 times a day). C (90 mg diltiazem sustained-release capsules once a day and 40 μg beraprost placebo 3 times a day) and D (90 mg diltiazem sustained-release capsules once a day and 40 μg beraprost 3 times a day). After 5 days' continuous administration of drug and placebo, results of 6-minute walk distance (6MWD) test, pulse oxygen saturation (SpO2), blood pressure (BP) and pulmonary artery systolic pressure (PASP), and incidence of adverse reactions before and after intervention were collected and compared among the groups. Results There were 13 cases lost during follow-up, and finally 187 participants were included. After intervention, the results of 6MWD test were obviously improved (t=-9.048, -9.555, -12.903, 95%CI: -45.582~-28.984, -46.391~-30.262, -63.205~-46.128, P < 0.05), PASP values (t=10.219, 9.380, 11.069, 95%CI: 2.304~3.435, 2.277~3.519, 2.636~3.809, P < 0.05) were significantly decreased in group B, group C and group D, and the SpO2 values (t=-4.071, -4.655, 95%CI: -1.311~-0.444, -2.569~-1.031, P < 0.05) were greatly increased in groups C and D. In addition, the participants from the groups B, C and D obtained significantly prolonged 6MWD results (F=7.246, P < 0.05) and lower PASP value (F=10.421, P < 0.05) after the treatment when compared with those of group A. Moreover, SpO2 in group D was significantly higher than that in groups A, B and C (F=6.896, P ...
    Keywords diltiazem ; beprost ; exercise endurance ; impact ; high altitude ; Medicine (General) ; R5-920
    Subject code 796
    Language Chinese
    Publishing date 2023-03-01T00:00:00Z
    Publisher Editorial Office of Journal of Army Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Peptidoglycan-based immunomodulation.

    Sun, Qingshen / Liu, Xiaoli / Li, Xiuliang

    Applied microbiology and biotechnology

    2022  Volume 106, Issue 3, Page(s) 981–993

    Abstract: Peptidoglycan (PGN) is a unique component in the cytoderm of prokaryotes which can be recognized by different pathogen-associated molecular patterns (PAMPs) in eukaryotes, followed by a cascade of immune responses via different pathways. This review ... ...

    Abstract Peptidoglycan (PGN) is a unique component in the cytoderm of prokaryotes which can be recognized by different pathogen-associated molecular patterns (PAMPs) in eukaryotes, followed by a cascade of immune responses via different pathways. This review outlined the basic structure of PGN, its immunologic functions. The immunomodulation pathways mediated by PGN were elaborated. PGN induces specific immunity through stimulating different cytokine release and Th1/Th2-dominated immune responses during humoral/cellular immune response. The nonspecific immunity activation by PGN involves immunomodulation by different pattern recognition receptors (PRRs) including PGN recognition proteins (PGRPs), nucleotide oligomerization domain (NOD)-like receptors (NLRs), Toll-like receptors (TLRs), and C-type lectin receptors (CLRs). The sources and classification of PGRPs were summarized. In view of the stimulating activities of PGN and its monomers, the potential application of PGN as vaccine or adjuvant was prospected. This review provides systematic information on PGN functionalities from the point of immunoregulation, which might be useful in the deep exploitation of PGN.Key points. The immunological functions of PGN were illustrated. Cellular and humoral immunomodulation by PGN were outlined. The use of PGN as vaccine or adjuvant was prospected.
    MeSH term(s) Cytokines ; Immunity, Innate ; Immunomodulation ; Peptidoglycan ; Toll-Like Receptors
    Chemical Substances Cytokines ; Peptidoglycan ; Toll-Like Receptors
    Language English
    Publishing date 2022-01-25
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-022-11795-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Biomarkers and coptis chinensis activity for rituximab-resistant diffuse large B-cell lymphoma: Combination of bioinformatics analysis, network pharmacology and molecular docking.

    Zhao, Qiuling / Huang, Shengqiang / Yang, Lin / Chen, Ting / Qiu, Xiuliang / Huang, Ruyi / Dong, Liangliang / Liu, Wenbin

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2024  

    Abstract: Background: Rituximab resistance is one of the great challenges in the treatment of diffuse large B-cell lymphoma (DLBCL), but relevant biomarkers and signalling pathways remain to be identified. Coptis chinensis and its active ingredients have ... ...

    Abstract Background: Rituximab resistance is one of the great challenges in the treatment of diffuse large B-cell lymphoma (DLBCL), but relevant biomarkers and signalling pathways remain to be identified. Coptis chinensis and its active ingredients have antitumour effects; thus, the potential bioactive compounds and mechanisms through which Coptis chinensis acts against rituximab-resistant DLBCL are worth exploring.
    Objective: To elucidate the core genes involved in rituximab-resistant DLBCL and the potential therapeutic targets of candidate monomers of Coptis chinensis.
    Methods: Using the Traditional Chinese Medicine System Pharmacology Database and Analysis Platform (TCMSP), the Similarity Ensemble Approach and Swiss Target Prediction, the main ingredients and pharmacological targets of Coptis chinensis were identified through database searches. Through the overlap between the pharmacological targets of Coptis chinensis and the core targets of rituximab-resistant DLBCL, we identified the targets of Coptis chinensis against rituximab-resistant DLBCL and constructed an active compound-target interaction network. The targets and their corresponding active ingredients of Coptis chinensis against rituximab-resistant DLBCL were molecularly docked.
    Results: Berberine, quercetin, epiberberine and palmatine, the active components of Coptis chinensis, have great potential for improving rituximab-resistant DLBCL via PIK3CG.
    Conclusion: This study revealed biomarkers and Coptis chinensis-associated molecular functions for rituximab-resistant DLBCL.
    Language English
    Publishing date 2024-02-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-230738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Improving the Adsorption Properties of Keratin-Based Goat Hair Toward Reactive Dyes in Dyeing Wastewater by Steam Explosion

    Shijin Wei / Xiuliang Hou / Linyun Liu / Yue Tian / Wei Li / Helan Xu

    Journal of Natural Fibers, Vol 20, Iss

    2023  Volume 1

    Abstract: Keratin-based goat hair could be used bioadsorbent due to its large availability, biodegradability and low cost. Unfortunately, most available keratin adsorbents are either low in adsorption capacity or high in preparation cost. In this study, goat hair ... ...

    Abstract Keratin-based goat hair could be used bioadsorbent due to its large availability, biodegradability and low cost. Unfortunately, most available keratin adsorbents are either low in adsorption capacity or high in preparation cost. In this study, goat hair was steam exploded, frozen and disintegrated to prepare the exploded goat hair powder (EGHP), and was further used for the adsorption of reactive blue 19 (RB 19) in dyeing wastewater. Steam explosion significantly increased the adsorption capacity of keratin-based goat hair toward RB 19. Adsorption capacity of RB 19 in EGHP increased from 55 to 427 mg/g after a steam explosion under 1.8 MPa for 150 s. The increased adsorption capacity was mainly due to decreased crystallinity, increased specific surface area from 0.678 to 8.583 m2/g and the increased free NH2 groups for EGHP. These structure changes resulted in that more dye molecules could easily and fast entered into the amorphous region of EGHP, thereby improving the adsorption rate and amount of RB 19 dyes. Desorption and regeneration study indicated that the adsorption capacity still maintained 79% after 6 cycles. These results demonstrated that EGHP could be considered as promising bioadsorbent to treat the dyeing wastewater.
    Keywords keratin-based goat hair ; reactive dyes ; dyeing wastewater ; steam explosion ; bioadsorbent ; ecological application of protein fiber ; Science ; Q ; Textile bleaching ; dyeing ; printing ; etc ; TP890-933
    Subject code 660
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Improving the Dyeing Properties of Peanut Skin Extracts to Flax Fabrics by Chitosan Pretreatment

    Qianqian Liu / Yu Zhang / Zixing Ma / Yingkun Wang / Yue Tian / Helan Xu / Xiuliang Hou

    Journal of Natural Fibers, Vol 20, Iss

    2023  Volume 2

    Abstract: Using chitosan as pretreatment agent, the dyeing properties of peanut skin extracts (PSE) to flax fabrics were improved. Flax fabrics have excellent comfort property and are loved by many people. However, flax is different to dye, especially with natural ...

    Abstract Using chitosan as pretreatment agent, the dyeing properties of peanut skin extracts (PSE) to flax fabrics were improved. Flax fabrics have excellent comfort property and are loved by many people. However, flax is different to dye, especially with natural dye. In this research, chitosan was used to pretreat flax fabrics and PSE was used to dye the pretreated flax fabric. The optimal conditions of the chitosan pretreatment and dyeing conditions of PSE were investigated according to the K/S value of the dyed flax fabrics. Comparing the original flax fabric, the chitosan pretreated flax fabric significantly improved the absorption to PSE, and the dyed fabrics had an increased K/S value from 0.9 to 3.9, and had good color fastnesses. The main chemical constitution in PSE such as catechin, chitosan, and cellulose of flax fabrics may form hydrogen bond and ionic bond. Chitosan pretreated and dyed flax fabrics had a stronger ability to UV resistance and scavenging free radicals. The fluorescence intensity of the dyed flax fabrics was improved while it was decreased after chitosan pretreatment. Chitosan pretreatment combined PSE dyeing can be used to develop functional flax textiles without using metallic mordants.
    Keywords peanut skin extracts ; chitosan pretreatment ; flax fabrics ; dyeing ; natural dyestuff ; functionality ; Science ; Q ; Textile bleaching ; printing ; etc ; TP890-933
    Subject code 540
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Impact of Economic Accessibility on Realized Utilization of Home-Based Healthcare Services for the Older Adults in China

    Xiaodong Di / Lijian Wang / Liu Yang / Xiuliang Dai

    Healthcare, Vol 9, Iss 2, p

    2021  Volume 218

    Abstract: Home-based healthcare service has gradually become the most important model to cope with aging in China. However, the contradiction between oversupply and insufficient demand of healthcare services is becoming increasingly serious. How to effectively ... ...

    Abstract Home-based healthcare service has gradually become the most important model to cope with aging in China. However, the contradiction between oversupply and insufficient demand of healthcare services is becoming increasingly serious. How to effectively improve the realized utilization of healthcare resources has become a key issue in the development of healthcare services. Based on the social background of “getting old before getting rich”, this article explores the relationship between economic accessibility and realized utilization, and finds that the impact of economic accessibility on realized utilization is inverted U-shaped, not a linear positive effect. In addition, considering the moderating role of family support, it is found that family support can strengthen the inverted U-shaped effect of economic accessibility on realized utilization. Therefore, exerting the role of family and improving economic accessibility can effectively solve the dilemma of low utilization of healthcare services.
    Keywords economic accessibility ; realized utilization ; family support ; inverted U-shaped effect ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Peptidoglycan-based immunomodulation

    Sun, Qingshen / Liu, Xiaoli / Li, Xiuliang

    Applied microbiology and biotechnology. 2022 Feb., v. 106, no. 3

    2022  

    Abstract: Peptidoglycan (PGN) is a unique component in the cytoderm of prokaryotes which can be recognized by different pathogen-associated molecular patterns (PAMPs) in eukaryotes, followed by a cascade of immune responses via different pathways. This review ... ...

    Abstract Peptidoglycan (PGN) is a unique component in the cytoderm of prokaryotes which can be recognized by different pathogen-associated molecular patterns (PAMPs) in eukaryotes, followed by a cascade of immune responses via different pathways. This review outlined the basic structure of PGN, its immunologic functions. The immunomodulation pathways mediated by PGN were elaborated. PGN induces specific immunity through stimulating different cytokine release and Th1/Th2-dominated immune responses during humoral/cellular immune response. The nonspecific immunity activation by PGN involves immunomodulation by different pattern recognition receptors (PRRs) including PGN recognition proteins (PGRPs), nucleotide oligomerization domain (NOD)–like receptors (NLRs), Toll-like receptors (TLRs), and C-type lectin receptors (CLRs). The sources and classification of PGRPs were summarized. In view of the stimulating activities of PGN and its monomers, the potential application of PGN as vaccine or adjuvant was prospected. This review provides systematic information on PGN functionalities from the point of immunoregulation, which might be useful in the deep exploitation of PGN.Key points. The immunological functions of PGN were illustrated. Cellular and humoral immunomodulation by PGN were outlined. The use of PGN as vaccine or adjuvant was prospected.
    Keywords adjuvants ; biotechnology ; cell-mediated immunity ; cytokines ; eukaryotic cells ; immunomodulation ; lectins ; microbiology ; oligomerization ; peptidoglycans ; prokaryotic cells ; vaccines
    Language English
    Dates of publication 2022-02
    Size p. 981-993.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-022-11795-4
    Database NAL-Catalogue (AGRICOLA)

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