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  1. Article ; Online: Adapted vaccine strategy: facing the persistent challenges of COVID-19.

    Shang, Lianhan / Cao, Bin

    The Lancet. Infectious diseases

    2023  Volume 23, Issue 9, Page(s) 984–985

    MeSH term(s) Humans ; COVID-19/prevention & control ; COVID-19 Vaccines
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00370-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Protein-based vaccine as the booster dose for adults: evidence and beyond.

    Shang, Lianhan / Cao, Bin

    The Lancet. Infectious diseases

    2022  Volume 22, Issue 11, Page(s) 1515–1517

    MeSH term(s) Adult ; Humans ; Immunization, Secondary ; Vaccination ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-08-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(22)00447-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Guarding a city from the COVID-19 pandemic.

    Xu, Jiuyang / Shang, Lianhan / Cao, Bin

    The Lancet. Digital health

    2020  Volume 2, Issue 6, Page(s) e275–e276

    MeSH term(s) COVID-19 ; China ; Cities ; Cohort Studies ; Humans ; Pandemics ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2589-7500
    ISSN (online) 2589-7500
    DOI 10.1016/S2589-7500(20)30111-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Contemporary narrative review of treatment options for COVID-19.

    Shang, Lianhan / Lye, David Chien / Cao, Bin

    Respirology (Carlton, Vic.)

    2021  Volume 26, Issue 8, Page(s) 745–767

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic is ongoing and many drugs have been studied in clinical trials. From a pathophysiological perspective, anti-viral drugs may be more effective in the early stage while immunomodulators may be more effective ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic is ongoing and many drugs have been studied in clinical trials. From a pathophysiological perspective, anti-viral drugs may be more effective in the early stage while immunomodulators may be more effective in severe patients in later stages of infection. While drugs such as lopinavir-ritonavir, hydroxychloroquine and azithromycin have proved to be ineffective in randomized controlled trials, corticosteroids, neutralizing monoclonal antibodies, remdesivir, tocilizumab and baricitinib have been reported to benefit certain groups of patients with COVID-19. In this review, we will present the key clinical evidence and progress in promising COVID-19 therapeutics, as well as summarize the experience and lessons learned from the development of the current therapeutics.
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/epidemiology ; Humans ; Pandemics ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-07-08
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4957: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Viral pneumonia in China: from surveillance to response.

    Shang, Lianhan / Xu, Jiuyang / Cao, Bin

    The Lancet. Public health

    2020  Volume 5, Issue 12, Page(s) e633–e634

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antiviral Agents/therapeutic use ; China/epidemiology ; Community-Acquired Infections ; Humans ; Immunocompromised Host ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Public Health Surveillance/methods ; Viral Vaccines/administration & dosage
    Chemical Substances Anti-Bacterial Agents ; Antiviral Agents ; Viral Vaccines
    Language English
    Publishing date 2020-11-24
    Publishing country England
    Document type Journal Article
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(20)30264-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Guarding a city from the COVID-19 pandemic

    Xu, Jiuyang / Shang, Lianhan / Cao, Bin

    The Lancet Digital Health

    2020  Volume 2, Issue 6, Page(s) e275–e276

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2589-7500
    DOI 10.1016/s2589-7500(20)30111-4
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article ; Online: On the use of corticosteroids for 2019-nCoV pneumonia.

    Shang, Lianhan / Zhao, Jianping / Hu, Yi / Du, Ronghui / Cao, Bin

    Lancet (London, England)

    2020  Volume 395, Issue 10225, Page(s) 683–684

    MeSH term(s) Adrenal Cortex Hormones ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Humans ; Lung Injury ; Pandemics ; Pneumonia ; Pneumonia, Viral/drug therapy ; SARS-CoV-2
    Chemical Substances Adrenal Cortex Hormones
    Keywords covid19
    Language English
    Publishing date 2020-02-12
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)30361-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 94: Show issues

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  10. Article ; Online: Impact of Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluid on Antimicrobial Stewardship in Patients With Lower Respiratory Tract Infections: A Retrospective Cohort Study.

    Yan, Mengwei / Zou, Xiaohui / Wang, Yeming / Wang, Chenhui / Wang, Yimin / Liu, Zhibo / Shang, Lianhan / Cui, Xiaojing / Cao, Bin

    The Journal of infectious diseases

    2023  Volume 229, Issue 1, Page(s) 223–231

    Abstract: Background: The impact of metagenomic next-generation sequencing (mNGS) on antimicrobial stewardship in patients with lower respiratory tract infections (LRTIs) is still unknown.: Methods: This retrospective cohort study included patients who had ... ...

    Abstract Background: The impact of metagenomic next-generation sequencing (mNGS) on antimicrobial stewardship in patients with lower respiratory tract infections (LRTIs) is still unknown.
    Methods: This retrospective cohort study included patients who had LRTIs diagnosed and underwent bronchoalveolar lavage between September 2019 and December 2020. Patients who underwent both mNGS and conventional microbiologic tests were classified as the mNGS group, while those with conventional tests only were included as a control group. A 1:1 propensity score match for baseline variables was conducted, after which changes in antimicrobial stewardship between the 2 groups were assessed.
    Results: A total of 681 patients who had an initial diagnosis of LRTIs and underwent bronchoalveolar lavage were evaluated; 306 patients were finally included, with 153 in each group. mNGS was associated with lower rates of antibiotic escalation than in the control group (adjusted odds ratio, 0.466 [95% confidence interval, .237-.919]; P = .02), but there was no association with antibiotic de-escalation. Compared with the control group, more patients discontinued the use of antivirals in the mNGS group.
    Conclusions: The use of mNGS was associated with lower rates of antibiotic escalation and may facilitate the cessation of antivirals, but not contribute to antibiotic de-escalation in patients with LRTIs.
    MeSH term(s) Humans ; Bronchoalveolar Lavage Fluid ; Antimicrobial Stewardship ; Retrospective Studies ; High-Throughput Nucleotide Sequencing ; Respiratory Tract Infections/drug therapy ; Anti-Bacterial Agents/therapeutic use ; Dimercaprol ; Metagenomics ; Antiviral Agents ; Sensitivity and Specificity
    Chemical Substances Anti-Bacterial Agents ; Dimercaprol (0CPP32S55X) ; Antiviral Agents
    Language English
    Publishing date 2023-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiad296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.50: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

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