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  1. Book: El Ecuador de la Postguerra , estudios en homenaje a Guillermo Perez Chiriboga

    Luma Tamayo, Milton / Pérez Chiriboga, Guillermo

    1992  

    Language Spanish
    Size 404 S, graph. Darst., 1. Portr
    Edition 1. Ed
    Publisher Banco Central del Ecuador
    Publishing place Ecuador
    Document type Book
    ISBN 997872222X ; 9789978722220
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book: El Ecuador de la Postguerra , estudios en homenaje a Guillermo Perez Chiriboga

    Luma Tamayo, Milton / Pérez Chiriboga, Guillermo

    1992  

    Language Spanish
    Size S. 411 - 842
    Edition 1. Ed
    Publisher Banco Central del Ecuador
    Publishing place Ecuador
    Document type Book
    ISBN 9978722238 ; 9789978722237
    Database Former special subject collection: coastal and deep sea fishing

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  3. Article: Editorial: Keep Calm and Care for Your Microbiota: The Role of

    Grande, Rossella / Perez Perez, Guillermo I

    Frontiers in microbiology

    2021  Volume 12, Page(s) 692472

    Language English
    Publishing date 2021-07-14
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.692472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Physical condition and perceived fatigue in post-covid patients: An observational descriptive study.

    Iturriaga, Tamara / Salazar-Pérez, Fernanda / Casallo-Cerezo, Marta / García-Pérez-de-Sevilla, Guillermo / Sosa-Pedreschi, Alicia / Diez-Vega, Ignacio / Supervia, Marta / Arroyo, Olga / Pérez-Ruiz, Margarita

    Sao Paulo medical journal = Revista paulista de medicina

    2024  Volume 142, Issue 4, Page(s) e2023167

    Abstract: Background: Patients with severe coronavirus disease 2019 (COVID-19) often require hospital admission and experience sequelae such as chronic fatigue or low muscle mass.: Objective: To analyze the functional capacity of a cohort of patients with ... ...

    Abstract Background: Patients with severe coronavirus disease 2019 (COVID-19) often require hospital admission and experience sequelae such as chronic fatigue or low muscle mass.
    Objective: To analyze the functional capacity of a cohort of patients with severe acute respiratory syndrome coronavirus 2 who required hospitalization.
    Design and setting: An observational descriptive study was conducted on post-COVID-19 patients referred to the Rehabilitation Department of Gregorio Marañón Hospital (Madrid, SPAIN).
    Methods: Cardiorespiratory fitness, muscle strength, body composition, and perception of fatigue and dyspnea were analyzed. Furthermore, the existing correlations between clinical variables and physical conditions were analyzed.
    Results: Forty-two patients who required hospital admission (80 ± 22.45 days) or intensive care unit (ICU) admission (58 ± 10.52 days) were analyzed. They presented with decreased strength, respiratory capacity, and moderate-to-severe perceived fatigue. Additionally, an inverse correlation was found between right-handgrip strength and days in the ICU, as well as the 6-minute walk test for women. Similarly, strength and fitness were negatively associated with perceived fatigue.
    Conclusions: Post-COVID-19 patients showed low muscle function and low levels of physical fitness associated with high perceived fatigue.
    MeSH term(s) Female ; Humans ; Body Composition ; Cardiorespiratory Fitness ; COVID-19 ; Disease Progression ; Hand Strength ; Male
    Language English
    Publishing date 2024-03-08
    Publishing country Brazil
    Document type Observational Study ; Journal Article
    ZDB-ID 1203171-9
    ISSN 1806-9460 ; 1516-3180 ; 0035-0362
    ISSN (online) 1806-9460
    ISSN 1516-3180 ; 0035-0362
    DOI 10.1590/1516-3180.2023.0167.R1.04122023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 184: Show issues Location:
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  5. Article ; Online: A prospective study to identify preoperative serum parameters for spinal implant infection detected by sonication fluid culture.

    García-Pérez, Daniel / García-Posadas, Guillermo / San-Juan, Rafael / Brañas, Patricia / Panero-Pérez, Irene / Delgado-Fernández, Juan / Paredes, Igor

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

    2023  Volume 32, Issue 5, Page(s) 1818–1829

    Abstract: Purpose: Low-virulent microorganisms identified on pedicle screws by sonication fluid culture (SFC) are an important cause of implant loosening. While sonication of explanted material improves the detection rate, the risk of contamination exists and no ... ...

    Abstract Purpose: Low-virulent microorganisms identified on pedicle screws by sonication fluid culture (SFC) are an important cause of implant loosening. While sonication of explanted material improves the detection rate, the risk of contamination exists and no standardized diagnostic criteria for chronic low-grade spinal implant-related infection (CLGSII) are stablished. Besides, the role of serum C-reactive protein (CRP) and procalcitonin (PCT) in CLGSII has not been adequately investigated.
    Methods: Blood samples were collected prior to implant removal. To increase sensitivity, the explanted screws were sonicated and processed separately. Patients exhibiting at least one positive SFC were classified in the infection group (loose criteria). To increase specificity, the strict criteria only considered multiple positive SFC (≥ 3 implants and/or ≥ 50% of explanted devices) as meaningful for CLGSII. Factors which might promote implant infection were also recorded.
    Results: Thirty-six patients and 200 screws were included. Among them, 18 (50%) patients had any positive SFCs (loose criteria), whereas 11 (31%) patients fulfilled the strict criteria for CLGSII. Higher serum protein level was the most accurate marker for the preoperative detection of CLGSSI, exhibiting an area under the curve of 0.702 (loose criteria) and 0.819 (strict criteria) for the diagnosis of CLGSII. CRP only exhibited a modest accuracy, whereas PCT was not a reliable biomarker. Patient history (spinal trauma, ICU hospitalization and/or previous wound-related complications) increased the likelihood of CLGSII.
    Conclusion: Markers of systemic inflammation (serum protein level) and patient history should be employed to stratify preoperative risk of CLGSII and decide the best treatment strategy.
    MeSH term(s) Humans ; Prospective Studies ; Prosthesis-Related Infections/diagnosis ; Prosthesis-Related Infections/etiology ; Sonication ; Device Removal/adverse effects ; Prostheses and Implants/adverse effects
    Language English
    Publishing date 2023-03-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1115375-1
    ISSN 1432-0932 ; 0940-6719
    ISSN (online) 1432-0932
    ISSN 0940-6719
    DOI 10.1007/s00586-023-07628-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3437: Show issues Location:
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  6. Article ; Online: Conscious Exploration of Alpha-Cuts in the Parametric Solution of the School Bus Routing Problem with Fuzzy Walking Distance.

    Sánchez-Ansola, Eduardo / Pérez-Pérez, Ana C / Rosete, Alejandro / Torres-Pérez, Isis / Rojas, Omar / Sosa-Gómez, Guillermo

    Computational intelligence and neuroscience

    2022  Volume 2022, Page(s) 4821927

    Abstract: Combinatorial optimization problems allow for modeling multiple situations in which proper allocation of resources is needed. For some real-world problems, the use of fuzzy elements in the models allows for incorporating certain levels of uncertainty to ... ...

    Abstract Combinatorial optimization problems allow for modeling multiple situations in which proper allocation of resources is needed. For some real-world problems, the use of fuzzy elements in the models allows for incorporating certain levels of uncertainty to better approximate such real-world situations. One way to solve combinatorial optimization problems with fuzzy elements is the parametric approach, where it is necessary to define how to explore different relaxation levels using alpha-cuts. Researchers tend to select such alpha-cuts uniformly. The current investigation proposes a novel strategy for selecting alpha-cuts in the School Bus Routing Problem with fuzzy students' maximum walking distance. This proposal bases its foundations on the number of student-bus stop pairs available according to the different levels of relaxations allowed. Results demonstrate how the proposed strategy gives attractive solutions with more diverse trade-offs, contrasted with other methods in the literature. Furthermore, it decreases the computational cost for those instances where the maximum relaxation does not provide new pairs of students-bus stops.
    MeSH term(s) Humans ; Schools ; Uncertainty ; Walking
    Language English
    Publishing date 2022-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388208-6
    ISSN 1687-5273 ; 1687-5273
    ISSN (online) 1687-5273
    ISSN 1687-5273
    DOI 10.1155/2022/4821927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Larvicidal Activity against Spodoptera frugiperda of some Constituents from two Diospyros Species. In silico Pesticide-likeness Properties, Acetylcholinesterase Activity and Molecular Docking.

    Pérez-Valera, Olivia / Torres-Martínez, Rafael / Nieto-Camacho, Antonio / Valencia, Israel / Javier Espinosa-García, Francisco / Delgado, Guillermo

    Chemistry & biodiversity

    2024  Volume 21, Issue 2, Page(s) e202301871

    Abstract: This report informs for the first time the chemical constituents of Diospyros xolocotzii and Diospyros digyna, the pesticidal and the acetylcholinesterase (AChE) inhibition potential of some compounds calculated by in silico approaches, the larvicidal ... ...

    Abstract This report informs for the first time the chemical constituents of Diospyros xolocotzii and Diospyros digyna, the pesticidal and the acetylcholinesterase (AChE) inhibition potential of some compounds calculated by in silico approaches, the larvicidal activity against Spodoptera frugiperda of available compounds, the AChE inhibition of selected compounds, and the results of the molecular docking of the most active ones with this receptor. From the aerial parts of D. xolocotzii were isolated pentacyclic triterpenes (1-4, 6, 10, 11-13), phytosterols (15-17), and isodiospyrin (18), whereas the analysis of aerial parts of D. digyna conducted to the isolation of pentacyclic triterpenes (4, 5, 7-9, 11-14), (4S)-shinanolone (19), and scopoletin (20). For comparison purposes, origanal (21) was chemically prepared from 11. The in silico analysis showed that the tested compounds have pesticide potential. The larvicidal activities of 11>13>12 indicated that the increase of the oxidation degree at C-28 increases their bioactivity. Compounds 11 and 21 presented the higher inhibition in the acetylcholinesterase assay, and the higher binding energies, and for the interactionswith AChE by molecular docking. Both Diospyros species are sources of triterpenes with pesticidal potential and the molecular changes in lupane triterpenes correlate with the observed bioactivity and molecular docking.
    MeSH term(s) Animals ; Molecular Docking Simulation ; Diospyros/chemistry ; Diospyros/metabolism ; Acetylcholinesterase/metabolism ; Spodoptera ; Pesticides ; Pentacyclic Triterpenes
    Chemical Substances Acetylcholinesterase (EC 3.1.1.7) ; Pesticides ; Pentacyclic Triterpenes
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202301871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comparing the direct assessment of steatosis in liver explants with mid- and near-infrared vibrational spectroscopy, prior to organ transplantation.

    Rienda, Iván / Moro, Erika / Pérez-Rubio, Álvaro / Trullenque-Juan, Ramón / Pérez-Guaita, David / Lendl, Bernhard / Kuligowski, Julia / Castell, Jose V / Pérez-Rojas, Judith / Pareja, Eugenia / Quintás, Guillermo

    The Analyst

    2023  Volume 148, Issue 17, Page(s) 3986–3991

    Abstract: A fast and accurate assessment of liver steatosis is crucial during liver transplantation surgery as it can negatively impact its success. Recent research has shown that near-infrared (NIR) and attenuated total reflectance-Fourier transform mid-infrared ( ...

    Abstract A fast and accurate assessment of liver steatosis is crucial during liver transplantation surgery as it can negatively impact its success. Recent research has shown that near-infrared (NIR) and attenuated total reflectance-Fourier transform mid-infrared (ATR-FTIR) spectroscopy could be used as real-time quantitative tools to assess steatosis during abdominal surgery. Here, in the frame of a clinical study, we explore the performance of NIR and ATR-FTIR spectroscopy for the direct assessment of steatosis in liver tissues. Results show that both NIR and ATR-FTIR spectroscopy are able to quantify the % of steatosis with cross-validation errors of 1.4 and 1.6%, respectively. Furthermore, the two portable instruments used both provided results within seconds and can be placed inside an operating room evidencing the potential of IR spectroscopy for initial characterization of grafts in liver transplantation surgery. We also evaluated the complementarity of the spectral ranges through correlation spectroscopy.
    MeSH term(s) Humans ; Fatty Liver ; Organ Transplantation ; Spectroscopy, Fourier Transform Infrared/methods ; Spectroscopy, Near-Infrared/methods
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an01184d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2423: Show issues Location:
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  9. Article ; Online: Real-world inter-observer variability of the Sequential Organ Failure Assessment (SOFA) score in intensive care medicine: the time has come for an update.

    Pérez-Torres, David / Merino-García, Pedro Alberto / Canas-Pérez, Isabel / Cuenca-Rubio, Cristina / Posadas-Pita, Guillermo Javier / Colmenero-Calleja, Cristina / Ticona-Espinoza, Thalia Gloria / Díaz-Rodríguez, Cristina

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 160

    MeSH term(s) Humans ; Organ Dysfunction Scores ; Observer Variation ; Critical Care ; Severity of Illness Index
    Language English
    Publishing date 2023-04-21
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04449-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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  10. Article: Helicobacter pylori

    Li, Jackie / Perez-Perez, Guillermo I

    Frontiers in microbiology

    2018  Volume 9, Page(s) 609

    Abstract: We dedicated this review to ... ...

    Abstract We dedicated this review to discuss
    Language English
    Publishing date 2018-04-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2018.00609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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