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  1. Article: Hydrothermal processes and simultaneous enzymatic hydrolysis in the production of modified cassava starches with porous-surfaces.

    Jorge, Figueroa-Flórez / Edith, Cadena-Chamorro / Eduardo, Rodríguez-Sandoval / Jairo, Salcedo-Mendoza / Héctor, Ciro-Velásquez

    Heliyon

    2023  Volume 9, Issue 7, Page(s) e17742

    Abstract: The amylolytic action of α-amylase and amyloglucosidase has been directly implemented in native cassava starches for the formation of cassava microporous granules with unsatisfactory results, however, its incidence in hydrothermally treated granules has ... ...

    Abstract The amylolytic action of α-amylase and amyloglucosidase has been directly implemented in native cassava starches for the formation of cassava microporous granules with unsatisfactory results, however, its incidence in hydrothermally treated granules has never been evaluated. The effect of hydrothermal processes and simultaneous enzymatic hydrolysis on the physicochemical, morphological and structural properties of native cassava starch was evaluated. Native cassava starch presented a rigid, smooth surface, and was exempt from porosities, whereas hydrothermal processes altered the semicrystalline order and increasing the size and number of pores and increasing the size (4.11 ± 0.09 nm) and volume of pores (0.82 ± 0.00 cm
    Language English
    Publishing date 2023-07-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e17742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Coronavirus disease 2019 drug discovery through molecular docking.

    Singh, Sweta / Florez, Hector

    F1000Research

    2020  Volume 9, Page(s) 502

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Antiviral Agents/chemistry ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections ; Drug Discovery ; Humans ; Molecular Docking Simulation ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-06-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.24218.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Bioinformatic study to discover natural molecules with activity against COVID-19.

    Singh, Sweta / Florez, Hector

    F1000Research

    2020  Volume 9, Page(s) 1203

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Antiviral Agents/chemistry ; Betacoronavirus/drug effects ; COVID-19 ; China ; Computational Biology ; Coronavirus Infections/drug therapy ; Drug Discovery ; Humans ; Molecular Docking Simulation ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2
    Chemical Substances Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-10-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.26731.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Covid-19 Dashboard

    Hector Florez / Sweta Singh

    2020  

    Abstract: COVID-19 Dashboard is an online information system to analyze the current state of the COVID- ... ...

    Abstract COVID-19 Dashboard is an online information system to analyze the current state of the COVID-19
    Keywords COVID-19 ; Dashboard ; Data Analysis ; covid19
    Language English
    Publishing date 2020-05-04
    Publishing country eu
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online: Molecular Docking ZINC DB

    Sweta Singh / Hector Florez

    2020  

    Abstract: Molecular docking to discover natural molecules against COVID- ... ...

    Abstract Molecular docking to discover natural molecules against COVID-19
    Keywords Molecular Docking ; covid19
    Language English
    Publishing date 2020-09-25
    Publishing country eu
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Effect of the Surface Chemical Composition on the Corrosion Resistance in the Mixture of FeCrMoNbB (140MXC) and FeCMnSi (530AS) Coatings Produced with the Electric Wire Arc Spraying Technique: Part I.

    Rojas-Molano, Héctor F / Olaya-Flórez, Jhon J / Guzmán-Pardo, María A / Alfonso-Orjuela, José E / Mendieta-Reyes, Néstor E

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 11

    Abstract: In this study, FeCrMoNbB (140MXC) and FeCMnSi (530AS) coatings were simultaneously projected on the substrate AISI-SAE 4340 using the electric wire arc spraying technique. The projection parameters, such as current (I), voltage (V), primary air pressure ( ...

    Abstract In this study, FeCrMoNbB (140MXC) and FeCMnSi (530AS) coatings were simultaneously projected on the substrate AISI-SAE 4340 using the electric wire arc spraying technique. The projection parameters, such as current (I), voltage (V), primary air pressure (1st), and secondary air pressure (2nd), were determined using the experimental model Taguchi L9 (3
    Language English
    Publishing date 2023-06-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16114182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Online dashboard and data analysis approach for assessing COVID-19 case and death data.

    Florez, Hector / Singh, Sweta

    F1000Research

    2020  Volume 9, Page(s) 570

    Abstract: The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization ... ...

    Abstract The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization reported 3,096,626 cases and 217,896 deaths, which implies an exponential growth for infection and deaths worldwide. Currently, there are various computer-based approaches that present COVID-19 data through different types of charts, which is very useful to recognise its behavior and trends. Nevertheless, such approaches do not allow for observation of any projection regarding confirmed cases and deaths, which would be useful to understand the trends of COVID-19. In this work, we have designed and developed an online dashboard that presents actual information about COVID-19. Furthermore, based on this information, we have designed a mathematical model in order to make projections about the evolution of cases and deaths worldwide and by country.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/mortality ; Data Analysis ; Humans ; Internet ; Models, Theoretical ; Pandemics ; Pneumonia, Viral/mortality ; SARS-CoV-2 ; Software
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.24164.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hydrothermal processes and simultaneous enzymatic hydrolysis in the production of modified cassava starches with porous-surfaces

    Figueroa-Flórez Jorge / Cadena-Chamorro Edith / Rodríguez-Sandoval Eduardo / Salcedo-Mendoza Jairo / Ciro-Velásquez Héctor

    Heliyon, Vol 9, Iss 7, Pp e17742- (2023)

    2023  

    Abstract: The amylolytic action of α-amylase and amyloglucosidase has been directly implemented in native cassava starches for the formation of cassava microporous granules with unsatisfactory results, however, its incidence in hydrothermally treated granules has ... ...

    Abstract The amylolytic action of α-amylase and amyloglucosidase has been directly implemented in native cassava starches for the formation of cassava microporous granules with unsatisfactory results, however, its incidence in hydrothermally treated granules has never been evaluated. The effect of hydrothermal processes and simultaneous enzymatic hydrolysis on the physicochemical, morphological and structural properties of native cassava starch was evaluated. Native cassava starch presented a rigid, smooth surface, and was exempt from porosities, whereas hydrothermal processes altered the semicrystalline order and increasing the size and number of pores and increasing the size (4.11 ± 0.09 nm) and volume of pores (0.82 ± 0.00 cm3/g × 10−3). The hydrothermal action followed by enzymatic processes with α-amylase and amyloglucosidase, augmented the processes of internal degradation (endo-erosion) and pore widening (exo-erosion), improving the hydrophilic properties compared to the hydrothermal treatment. Likewise, the hydrothermally process followed by enzymatic hydrolysis for 24 h (HPS + EMS-24) increased the degradation of the amorphous lamellae, consistent with a significant decrease in amylose content. This same dual treatment increased the pore size at 17.68 ± 0.13 nm relative to the native counterpart; therefore, they are considered an effective method in the development of modified cassava starches with porous surfaces.
    Keywords Porous surfaces ; Hydrothermal processes ; Enzymatic hydrolysis ; Cassava starch ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 660
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Online dashboard and data analysis approach for assessing COVID-19 case and death data [version 1; peer review

    Hector Florez / Sweta Singh

    F1000Research, Vol

    2 approved, 1 approved with reservations]

    2020  Volume 9

    Abstract: The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization ... ...

    Abstract The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization reported 3,096,626 cases and 217,896 deaths, which implies an exponential growth for infection and deaths worldwide. Currently, there are various computer-based approaches that present COVID-19 data through different types of charts, which is very useful to recognise its behavior and trends. Nevertheless, such approaches do not allow for observation of any projection regarding confirmed cases and deaths, which would be useful to understand the trends of COVID-19. In this work, we have designed and developed an online dashboard that presents actual information about COVID-19. Furthermore, based on this information, we have designed a mathematical model in order to make projections about the evolution of cases and deaths worldwide and by country.
    Keywords Medicine ; R ; Science ; Q ; covid19
    Subject code 306
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Coronavirus disease 2019 drug discovery through molecular docking [version 1; peer review

    Sweta Singh / Hector Florez

    F1000Research, Vol

    1 approved, 2 approved with reservations]

    2020  Volume 9

    Abstract: Background: The dawn of the year 2020 witnessed the spread of the highly infectious and communicable disease coronavirus disease 2019 (COVID-19) globally since it was first reported in 2019. Severe acute respiratory syndrome coronavirus-2 is the main ... ...

    Abstract Background: The dawn of the year 2020 witnessed the spread of the highly infectious and communicable disease coronavirus disease 2019 (COVID-19) globally since it was first reported in 2019. Severe acute respiratory syndrome coronavirus-2 is the main causative agent. In total, 3,096,626 cases and 217,896 deaths owing to COVID-19 were reported by 30th April, 2020 by the World Health Organization. This means infection and deaths show an exponential growth globally. In order to tackle this pandemic, it is necessary to find possible easily accessible therapeutic agents till an effective vaccine is developed. Methods: In this study, we present the results of molecular docking processes through high throughput virtual screening to analyze drugs recommended for the treatment of COVID-19. Results: Atovaquone, fexofenadine acetate (Allegra), ethamidindole, baicalin, glycyrrhetic acid, justicidin D, euphol, and curine are few of the lead molecules found after docking 129 known antivirals, antimalarial, antiparasitic drugs and 992 natural products. Conclusions: These molecules could act as an effective inhibitory drug against COVID-19.
    Keywords Medicine ; R ; Science ; Q ; covid19
    Subject code 630
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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