LIVIVO - Search results -

Search results

Result 1 - 10 of total 37

Search options

Article: Open-source do-it-yourself multi-color fluorescence smartphone microscopy.

Sung, Yulung / Campa, Fernando / Shih, Wei-Chuan

2017 Volume 8, Issue 11, Page(s) 5075–5086

Abstract: Fluorescence microscopy is an important technique for cellular and microbiological investigations. Translating this technique onto a smartphone can enable particularly powerful applications such as on-site analysis, on-demand monitoring, and point-of- ... ...

Abstract	Fluorescence microscopy is an important technique for cellular and microbiological investigations. Translating this technique onto a smartphone can enable particularly powerful applications such as on-site analysis, on-demand monitoring, and point-of-care diagnostics. Current fluorescence smartphone microscope setups require precise illumination and imaging alignment which altogether limit its broad adoption. We report a multi-color fluorescence smartphone microscope with a single contact lens-like add-on lens and slide-launched total-internal-reflection guided illumination for three common tasks in investigative fluorescence microscopy: autofluorescence, fluorescent stains, and immunofluorescence. The open-source, simple and cost-effective design has the potential for do-it-yourself fluorescence smartphone microscopy.
Language	English
Publishing date	2017-10-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.8.005075
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Smartphone Nanocolorimetry for On-Demand Lead Detection and Quantitation in Drinking Water.

Nguyen, Hoang / Sung, Yulung / O'Shaughnessy, Kelly / Shan, Xiaonan / Shih, Wei-Chuan

Analytical chemistry

2018 Volume 90, Issue 19, Page(s) 11517–11522

Abstract: Lead ions ( ... ...

Abstract	Lead ions (Pb
MeSH term(s)	Chromates/chemistry ; Colorimetry/instrumentation ; Colorimetry/methods ; Drinking Water/analysis ; Lead/analysis ; Lead/chemistry ; Limit of Detection ; Metal Nanoparticles/chemistry ; Potassium Compounds/chemistry ; Smartphone ; Water Pollutants, Chemical/analysis
Chemical Substances	Chromates ; Drinking Water ; Potassium Compounds ; Water Pollutants, Chemical ; Lead (2P299V784P) ; potassium chromate(VI) (5P0R38CN2X) ; lead chromate (AA3229AOUS)
Language	English
Publishing date	2018-09-14
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.8b02808
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4033: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Smartphone Nanocolorimetry for On-Demand Lead Detection and Quantitation in Drinking Water

Nguyen, Hoang / Kelly O’Shaughnessy / Wei-Chuan Shih / Xiaonan Shan / Yulung Sung

Analytical chemistry. 2018 Sept. 02, v. 90, no. 19

2018

Abstract: Lead ions (Pb2+) contamination in drinking water, a major source of lead poisoning to the general population, is typically detected by bulky and costly laboratory analytical instrument. A mobile analytical device for rapid Pb2+ sensing is a growing ... ...

Abstract	Lead ions (Pb2+) contamination in drinking water, a major source of lead poisoning to the general population, is typically detected by bulky and costly laboratory analytical instrument. A mobile analytical device for rapid Pb2+ sensing is a growing demand. Herein, we report smartphone nanocolorimetry (SNC) as a new technique to detect and quantify dissolved Pb2+ in drinking water. Specifically, we have employed a single-step sedimentation approach by mixing a controlled quantity of chromate ion (CrO42–) to react with Pb2+ containing solutions to form highly insoluble lead chromate (PbCrO4) nanoparticles as vivid yellow precipitates. This is followed by microscopic color detection and intensity quantitation at nanoscale level using dark-field smartphone microscopy. The sum of the intensity of yellow pixels bears a highly reproducible relationship with Pb2+ concentration between 1.37 and 175 ppb in deionized water and 5–175 ppb in city tap water. In contrast to traditional colorimetric techniques analyzing bulk color changes, SNC achieves unparalleled sensitivity by combining nanocolorimetry with dark-field microscopy and mobilized the metal ions detection by integrating the detection into the smartphone microscope platform. SNC is rapid and low-cost and has the potential to enable individual citizens to examine Pb2+ content in drinking water on-demand in virtually any environmental setting.
Keywords	chromates ; color ; colorimetry ; lead ; lead poisoning ; metal ions ; microscopy ; mixing ; mobile telephones ; nanoparticles ; tap water
Language	English
Dates of publication	2018-0902
Size	p. 11517-11522.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.8b02808
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 4' 52/94: Show issues
Z 2.9: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Modeling the surface of fast-cured polymer droplet lenses for precision fabrication.

Sung, Yu-Lung / Garan, Jacob / Hu, Zhenyu / Shan, Xiaonan / Shih, Wei-Chuan

Applied optics

2019 Volume 57, Issue 35, Page(s) 10342–10347

Abstract: Optical lenses with diameter in the millimeter range have found important commercial use in smartphone cameras. Although these lenses are typically made by molding, recent demonstration of fast-cured polymer droplets by inkjet printing has gained ... ...

Abstract	Optical lenses with diameter in the millimeter range have found important commercial use in smartphone cameras. Although these lenses are typically made by molding, recent demonstration of fast-cured polymer droplets by inkjet printing has gained interest for cost-effective smartphone microscopy. In this technique, the surface of a fast-cured polydimethylsiloxane droplet obtains dynamic equilibrium via the interplay of surface tension, gravity, thermalization, and a steep viscosity hike. The nature of surface formation involves multiple physical and chemical domains, which represent significant challenges in modeling with the Young-Laplace theory, assuming constant surface tension and viscosity. To overcome these challenges, we introduce the concept of effective surface tension, which allows fast-cured polymer droplets to be modeled as normal liquid droplets with constant viscosity.
Language	English
Publishing date	2019-01-15
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.57.010342
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Cellular retinoic acid binding protein 1 protects mice from high-fat diet-induced obesity by decreasing adipocyte hypertrophy.

Lin, Yi-Wei / Park, Sung Wook / Lin, Yu-Lung / Burton, Frank H / Wei, Li-Na

International journal of obesity (2005)

2019 Volume 44, Issue 2, Page(s) 466–474

Abstract: Objectives: Obesity, an emerging global health issue, involves numerous factors; understanding its underlying mechanisms for prevention and therapeutics is urgently needed. Cellular retinoic acid binding protein 1 (Crabp1) knockout (CKO) mice exhibit an ...

Abstract	Objectives: Obesity, an emerging global health issue, involves numerous factors; understanding its underlying mechanisms for prevention and therapeutics is urgently needed. Cellular retinoic acid binding protein 1 (Crabp1) knockout (CKO) mice exhibit an obese phenotype under normal diet (ND) feedings, which prompted us to propose that Crabp1 could play a role in modulating adipose tissue development/homeostasis. Studies were designed to elucidate the underlying mechanism of Crabp1's action in reducing obesity. Subjects/methods: In animal studies, 6 weeks old male wild type and CKO mice were fed with ND or high-fat diet (HFD) for 10 weeks. Body weight and food intake were regularly monitored. Glucose tolerance test and biological parameters of plasma (glucose and insulin levels) were measured after 10 weeks of ND vs. HFD feedings. Visceral adipose tissues were collected for histological and molecular analyses to determine affected signaling pathways. In cell culture studies, the 3T3L1 adipocyte differentiation model was used to examine and validate relevant signaling pathways. Results: CKO mice, compared to WT mice, gained more body weight, exhibited more elevated fasting plasma glucose levels, and developed more severe impaired glucose tolerance under both ND and HFD. Histological examination revealed readily increased adipocyte hypertrophy and adipose tissue inflammation under HFD feedings. In 3T3L1 adipocytes, Crabp1 silencing enhanced extracellular signal-regulated kinase 1/2 (ERK1/2) activation, accompanied by elevated markers and signaling pathways of lipid accumulation and adipocyte hypertrophy. Conclusions: This study identifies Crabp1's physiological role against the development of obesity. The protective function of CRABP1 is likely attributed to its classically proposed (canonical) activity as a trap for RA, which will reduce RA availability, thereby dampening RA-stimulated ERK1/2 activation and adipocyte hypertrophy. The results suggest Crabp1 as a potentially new therapeutic target in managing obesity and metabolic diseases.
MeSH term(s)	3T3-L1 Cells ; Adipocytes/metabolism ; Adipocytes/pathology ; Adipose Tissue, White/metabolism ; Adipose Tissue, White/pathology ; Animals ; Diet, High-Fat/adverse effects ; Hypertrophy/metabolism ; Hypertrophy/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Obesity/etiology ; Obesity/metabolism ; Receptors, Retinoic Acid/genetics ; Receptors, Retinoic Acid/metabolism
Chemical Substances	Receptors, Retinoic Acid ; retinoic acid binding protein I, cellular
Language	English
Publishing date	2019-06-04
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	752409-2
ISSN	1476-5497 ; 0307-0565
ISSN (online)	1476-5497
ISSN	0307-0565
DOI	10.1038/s41366-019-0379-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1325: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Correction to: Cellular retinoic acid binding protein 1 protects mice from high-fat diet-induced obesity by decreasing adipocyte hypertrophy.

Lin, Yi-Wei / Park, Sung Wook / Lin, Yu-Lung / Burton, Frank H / Wei, Li-Na

International journal of obesity (2005)

2019 Volume 43, Issue 11, Page(s) 2347

Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

Abstract	An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Language	English
Publishing date	2019-09-14
Publishing country	England
Document type	Published Erratum
ZDB-ID	752409-2
ISSN	1476-5497 ; 0307-0565
ISSN (online)	1476-5497
ISSN	0307-0565
DOI	10.1038/s41366-019-0449-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1325: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Automated batch characterization of inkjet-printed elastomer lenses using a LEGO platform.

Sung, Yu-Lung / Garan, Jacob / Nguyen, Hoang / Hu, Zhenyu / Shih, Wei-Chuan

Applied optics

2017 Volume 56, Issue 26, Page(s) 7346–7350

Abstract: Small, self-adhesive, inkjet-printed elastomer lenses have enabled smartphone cameras to image and resolve microscopic objects. However, the performance of different lenses within a batch is affected by hard-to-control environmental variables. We present ...

Abstract	Small, self-adhesive, inkjet-printed elastomer lenses have enabled smartphone cameras to image and resolve microscopic objects. However, the performance of different lenses within a batch is affected by hard-to-control environmental variables. We present a cost-effective platform to perform automated batch characterization of 300 lens units simultaneously for quality inspection. The system was designed and configured with LEGO bricks, 3D printed parts, and a digital camera. The scheme presented here may become the basis of a high-throughput, in-line inspection tool for quality control purposes and can also be employed for optimization of the manufacturing process.
Language	English
Publishing date	2017-09-10
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.56.007346
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Fabricating optical lenses by inkjet printing and heat-assisted in situ curing of polydimethylsiloxane for smartphone microscopy.

Sung, Yu-Lung / Jeang, Jenn / Lee, Chia-Hsiung / Shih, Wei-Chuan

Journal of biomedical optics

2015 Volume 20, Issue 4, Page(s) 47005

Abstract: We present a highly repeatable, lithography-free and mold-free method for fabricating flexible optical lenses by in situ curing liquid polydimethylsiloxane droplets on a preheated smooth surface with an inkjet printing process. This method enables us to ... ...

Abstract	We present a highly repeatable, lithography-free and mold-free method for fabricating flexible optical lenses by in situ curing liquid polydimethylsiloxane droplets on a preheated smooth surface with an inkjet printing process. This method enables us to fabricate lenses with a focal length as short as 5.6 mm, which can be controlled by varying the droplet volume and the temperature of the preheated surface. Furthermore, the lens can be attached to a smartphone camera without any accessories and can produce high-resolution (1 μm) images for microscopy applications.
MeSH term(s)	Computer Peripherals ; Dimethylpolysiloxanes/chemistry ; Equipment Design ; Equipment Failure Analysis ; Hardness ; Heating ; Hot Temperature ; Image Enhancement/instrumentation ; Lenses ; Microscopy/instrumentation ; Printing, Three-Dimensional/instrumentation ; Reproducibility of Results ; Sensitivity and Specificity ; Smartphone/instrumentation
Chemical Substances	Dimethylpolysiloxanes ; baysilon (63148-62-9)
Language	English
Publishing date	2015-04-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1309154-2
ISSN	1560-2281 ; 1083-3668
ISSN (online)	1560-2281
ISSN	1083-3668
DOI	10.1117/1.JBO.20.4.047005
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4699: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Ammonia vapor sensor based on CdSe/SiO₂ core–shell nanoparticles embedded in sol–gel matrix

Sung, Ti-Wen / Lo, Yu-Lung

Sensors & Actuators: B. Chemical. 2013 Nov., v. 188

2013

Abstract: A high-performance ammonia vapor sensor is proposed comprising CdSe/SiO₂ core–shell nanoparticles embedded in a sol–gel matrix immobilized on the tip of an optical fiber. The experimental results show that the luminescence intensity of the CdSe/SiO₂ ... ...

Abstract	A high-performance ammonia vapor sensor is proposed comprising CdSe/SiO₂ core–shell nanoparticles embedded in a sol–gel matrix immobilized on the tip of an optical fiber. The experimental results show that the luminescence intensity of the CdSe/SiO₂ nanoparticles reduces significantly when exposed to ammonia vapor. The fluorescence quenching effect is thought to be caused by the adsorption of the ammonia molecules at the trapped sites on the surface of the CdSe quantum dots (QDs). In addition, the proposed sensor exhibits good linearity for ammonia vapor concentrations between 10 and 400ppm, and has a detection limit of as little as 1.2ppm. Moreover, the sensor has a response time of 6.1s when switching from pure N₂ to a mixed N₂–ammonia vapor and 942.2s when switching in the reverse direction. Importantly, the signal changes are fully reversible when switching repeatedly between the two gaseous environments. Overall, the results show that the proposed sensor has many key advantages compared to optical sensors based on organic sensitive dye, including a higher response (I₀/I), an improved chemical stability, and full reversibility.
Keywords	adsorption ; ammonia ; detection limit ; fluorescence ; light intensity ; nanoparticles ; nitrogen ; quantum dots ; vapors
Language	English
Dates of publication	2013-11
Size	p. 702-708.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1021505-0
ISSN	0925-4005
ISSN	0925-4005
DOI	10.1016/j.snb.2013.07.040
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article: Dual sensing of temperature and oxygen using PtTFPP-doped CdSe/SiO₂ core–shell nanoparticles

Sung, Ti-Wen / Lo, Yu-Lung

Sensors & Actuators: B. Chemical. 2012 Oct., v. 173

2012

Abstract: A sensor comprising doped core–shell nanoparticles embedded in a sol–gel matrix is proposed for the dual sensing of temperature and oxygen. The nanoparticles comprise a CdSe quantum dot (QD) core and a silica shell doped with platinum(II) meso-tetrakis( ... ...

Abstract	A sensor comprising doped core–shell nanoparticles embedded in a sol–gel matrix is proposed for the dual sensing of temperature and oxygen. The nanoparticles comprise a CdSe quantum dot (QD) core and a silica shell doped with platinum(II) meso-tetrakis(pentafluorophenyl)porphyrin (PtTFPP). The core–shell nanoparticles provide a temperature sensing function while the platinum dye provides an oxygen sensing function. Both indicators are excited using a wavelength of 409nm. The doped nanoparticles are embedded in an n-propyltrimethoxysilane (n-propyl-TriMOS)/3,3,3-trifluoropropyltrimethoxysilane (TFP-TriMOS) composite xerogel and coated on the end of an optical fiber. The experimental results show that the shift in the emission wavelength has the thermal sensitivity of ∼0.095nm/°C over temperatures ranging from 30 to 100°C. Moreover, it is shown that the sensor enables the reliable measurement of oxygen concentrations in the range of 0–100% with a response (I₀/I) of approximately 18 under room temperature conditions. The response time was 0.37s when switching from nitrogen to oxygen, and 4.7s when switching in the reverse direction. Overall, the results presented in this study show that the proposed sensor provides an ideal solution for the dual sensing of oxygen and temperature in such applications as (micro)biological, medical and environmental fields.
Keywords	nanoparticles ; nitrogen ; oxygen ; platinum ; porphyrins ; quantum dots ; silica ; temperature ; wavelengths
Language	English
Dates of publication	2012-10
Size	p. 406-413.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1021505-0
ISSN	0925-4005
ISSN	0925-4005
DOI	10.1016/j.snb.2012.07.028
Database	NAL-Catalogue (AGRICOLA)

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito