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  1. Article ; Online: Iridium(III)-Catalyzed Regioselective B(4)-H Amination of

    Park, Kyeongna / Han, Gi Uk / Yoon, Sugyeong / Lee, Eunseo / Noh, Hee Chan / Lee, Kyungsup / Maeng, Chanyoung / Kim, Dongwook / Lee, Phil Ho

    Organic letters

    2023  Volume 25, Issue 32, Page(s) 5989–5994

    Abstract: Iridium(III)-catalyzed regioselective B(4)-H amination is developed from the reaction of ...

    Abstract Iridium(III)-catalyzed regioselective B(4)-H amination is developed from the reaction of
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c02114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Iridium(III)-Catalyzed Regioselective B(4)-H Allenylation of

    Shin, Seohyun / Um, Kyusik / Ko, Gi Hoon / Han, Gi Uk / Kim, Dongwook / Lee, Phil Ho

    Organic letters

    2022  Volume 24, Issue 17, Page(s) 3128–3133

    Abstract: We disclose an iridium(III)-catalyzed regioselective B(4)-H allenylation of ...

    Abstract We disclose an iridium(III)-catalyzed regioselective B(4)-H allenylation of
    Language English
    Publishing date 2022-04-25
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.2c00756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Direct and Regioselective Palladium(II)-Catalyzed B(4)-H Monoacyloxylation and B(4,5)-H Diacetoxylation of

    Ham, Hyeongcheol / Shin, Seohyun / Ko, Gi Hoon / Han, Sang Hoon / Han, Gi Uk / Maeng, Chanyoung / Kim, Tae Hyeon / Noh, Hee Chan / Lee, Kyungsup / Kim, Hanjoong / Yang, Heejin / Lee, Phil Ho

    The Journal of organic chemistry

    2021  Volume 86, Issue 21, Page(s) 15153–15163

    Abstract: A direct B(4)-H monoacyloxylation via a Pd-catalyzed regioselective B(4)-H activation of ...

    Abstract A direct B(4)-H monoacyloxylation via a Pd-catalyzed regioselective B(4)-H activation of
    Language English
    Publishing date 2021-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.1c01804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: An unusual case of microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) diffuse large B-cell lymphoma revealed by targeted gene sequencing.

    Han, Bogyeong / Kim, Sehui / Koh, Jiwon / Bae, Jeong Mo / Yun, Hongseok / Jeon, Yoon Kyung

    Journal of pathology and translational medicine

    2021  Volume 56, Issue 2, Page(s) 92–96

    Abstract: ... We report the case of an MSI-H/dMMR diffuse large B-cell lymphoma (DLBCL) identified by targeted gene ... Microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) status has been approved ... vagina was diagnosed with germinal center-B-cell-like DLBCL, which recurred at the uterine cervix at 9 ...

    Abstract Microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) status has been approved as a tissue-agnostic biomarker for immune checkpoint inhibitor therapy in patients with solid tumors. We report the case of an MSI-H/dMMR diffuse large B-cell lymphoma (DLBCL) identified by targeted gene sequencing (TGS). A 90-year-old female who presented with vaginal bleeding and a large mass in the upper vagina was diagnosed with germinal center-B-cell-like DLBCL, which recurred at the uterine cervix at 9 months after chemotherapy. Based on TGS of 121 lymphoma-related genes and the LymphGen algorithm, the tumor was classified genetically as DLBCL of EZB subtype. Mutations in multiple genes, including frequent frameshift mutations, were detected by TGS and further suggested MSI. The MSI-H/dMMR and loss of MLH1 and PMS2 expression were determined in MSI-fragment analysis, MSI real-time polymerase chain reaction, and immunohistochemical tests. This case demonstrates the potential diagnostic and therapeutic utility of lymphoma panel sequencing for DLBCL with MSI-H/dMMR.
    Language English
    Publishing date 2021-11-16
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3022395-7
    ISSN 2383-7845 ; 2383-7837
    ISSN (online) 2383-7845
    ISSN 2383-7837
    DOI 10.4132/jptm.2021.10.15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Changes in the expression of the B subunit of vacuolar H

    Jung, Hyo Young / Kim, Woosuk / Hahn, Kyu Ri / Kang, Min Soo / Kwon, Hyun Jung / Choi, Jung Hoon / Yoon, Yeo Sung / Kim, Dae Won / Yoo, Dae Young / Won, Moo-Ho / Hwang, In Koo

    Iranian journal of basic medical sciences

    2020  Volume 24, Issue 11, Page(s) 1482–1487

    Abstract: Objectives: Vacuolar H: Materials and methods: Transient forebrain ischemia was induced ...

    Abstract Objectives: Vacuolar H
    Materials and methods: Transient forebrain ischemia was induced by occlusion of both common carotid arteries for 5 min and animals were sacrificed at various time points after ischemia for immunohistochemical staining of ATP6V1B2 and measurements of pH and lactate levels in the hippocampus.
    Results: ATP6V1B2 immunoreactivity was found to be transiently increased in the hippocampal CA1 region and dentate gyrus 12-24 hr after ischemia when the pH and lactate levels were decreased. In addition, ATP6V1B2 immunoreactivity significantly increased in the hippocampal CA3 and dentate gyrus, regions relatively resistant to ischemic damage, 4 days after ischemia, when the NeuN-positive, mature neuron numbers were significantly decreased in the hippocampal CA1 region.
    Conclusion: These results suggest that ATP6V1B2 expression is transiently increased in the hippocampus following ischemia, which may be intended to compensate for ischemia-related dysfunction of ATP6V1B2 in the hippocampus.
    Language English
    Publishing date 2020-04-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    DOI 10.22038/IJBMS.2021.59275.13155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy.

    Son, Arang / Kang, Seoyeong / Choi, Suha / Shin, Sung-Won / Kim, Yeeun / Kim, Wankyu / Choi, Changhoon

    Neoplasia (New York, N.Y.)

    2022  Volume 35, Page(s) 100862

    Abstract: ... of Na-H exchange 1 (NHE1), the major intracellular pH (pH ...

    Abstract Intrinsic or acquired radioresistance often limits the efficacy of radiation therapy (RT), thereby leading to local control failure. Cancerous cells have abnormal pH dynamics due to high metabolic demands, but it is unclear how pH dynamics contribute to radioresistance. In this study, we investigated the role of Na-H exchange 1 (NHE1), the major intracellular pH (pH
    MeSH term(s) Humans ; Mice ; Animals ; Female ; NF-kappa B/metabolism ; Sodium-Hydrogen Exchangers/genetics ; Sodium-Hydrogen Exchangers/metabolism ; Sodium-Hydrogen Exchanger 1/genetics ; Sodium-Hydrogen Exchanger 1/metabolism ; Amiloride/pharmacology ; Apoptosis ; Breast Neoplasms/genetics ; Breast Neoplasms/radiotherapy ; Hydrogen-Ion Concentration
    Chemical Substances NF-kappa B ; Sodium-Hydrogen Exchangers ; Sodium-Hydrogen Exchanger 1 ; Amiloride (7DZO8EB0Z3)
    Language English
    Publishing date 2022-12-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1483840-0
    ISSN 1476-5586 ; 1522-8002
    ISSN (online) 1476-5586
    ISSN 1522-8002
    DOI 10.1016/j.neo.2022.100862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: B dopant evolution in Pd catalysts after H evolution/oxidation reaction in alkaline environment

    Kim, Se-Ho / Yoo, Su-Hyun / Aota, Leonardo Shoji / El-Zoka, Ayman / Kang, Philwoong / Lee, Yonghyuk / Gault, Baptiste

    2023  

    Abstract: ... show that the high stability of sub-surface B in Pd is substantially reduced when H is ad/absorbed ... of a property-enhancing dopant, B, introduced through controlled synthesis of an electrocatalyst Pd aerogel ... We observe significant removal of B after the hydrogen evolution/oxidation reaction. Ab-initio calculations ...

    Abstract Introduction of interstitial dopants has opened a new pathway to optimize nanoparticle catalytic activity for, e.g., hydrogen evolution/oxidation and other reactions. Here, we discuss the stability of a property-enhancing dopant, B, introduced through controlled synthesis of an electrocatalyst Pd aerogel. We observe significant removal of B after the hydrogen evolution/oxidation reaction. Ab-initio calculations show that the high stability of sub-surface B in Pd is substantially reduced when H is ad/absorbed on the surface, favoring its departure from the host nanostructure. The destabilization of sub-surface B is more pronounced as more H occupies surface sites and empty interstitial sites. We hence demonstrate that the H2 fuel/product itself favors the microstructural degradation of the electrocatalyst and an associated drop in activity.
    Keywords Condensed Matter - Materials Science
    Publishing date 2023-02-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: First Observation of the Hadronic Transition ϒ(4S)→ηh(b)(1P) and New Measurement of the h(b)(1P) and η(b)(1S) Parameters.

    Tamponi, U / Mussa, R / Abdesselam, A / Aihara, H / Arinstein, K / Asner, D M / Atmacan, H / Aushev, T / Ayad, R / Badhrees, I / Bakich, A M / Barberio, E / Bhardwaj, V / Bhuyan, B / Biswal, J / Bondar, A / Bonvicini, G / Bozek, A / Bračko, M /
    Browder, T E / Červenkov, D / Chen, A / Cheon, B G / Cho, K / Chobanova, V / Choi, S-K / Choi, Y / Cinabro, D / Danilov, M / Doležal, Z / Drásal, Z / Drutskoy, A / Eidelman, S / Epifanov, D / Farhat, H / Fast, J E / Ferber, T / Fulsom, B G / Gaur, V / Gabyshev, N / Garmash, A / Getzkow, D / Gillard, R / Goh, Y M / Golob, B / Haba, J / Hayasaka, K / Hayashii, H / He, X H / Hedges, M T / Hou, W-S / Iijima, T / Inami, K / Ishikawa, A / Jaegle, I / Joffe, D / Julius, T / Kato, E / Katrenko, P / Kichimi, H / Kiesling, C / Kim, D Y / Kim, H J / Kim, J H / Kim, K T / Kim, S H / Kinoshita, K / Kodyš, P / Korpar, S / Križan, P / Krokovny, P / Kumita, T / Kuzmin, A / Lange, J S / Lewis, P / Libby, J / Lukin, P / Matvienko, D / Miyabayashi, K / Miyata, H / Mizuk, R / Mohanty, G B / Moll, A / Mori, T / Nakano, E / Nakao, M / Nanut, T / Natkaniec, Z / Nayak, M / Nisar, N K / Nishida, S / Ogawa, S / Okuno, S / Olsen, S L / Ostrowicz, W / Oswald, C / Pakhlova, G / Pal, B / Park, H / Pedlar, T K / Pesántez, L / Pestotnik, R / Petrič, M / Piilonen, L E / Ribežl, E / Ritter, M / Rostomyan, A / Ryu, S / Sakai, Y / Sandilya, S / Santelj, L / Sanuki, T / Sato, Y / Savinov, V / Schneider, O / Schnell, G / Schwanda, C / Semmler, D / Senyo, K / Sevior, M E / Shapkin, M / Shebalin, V / Shen, C P / Shibata, T-A / Shiu, J-G / Shwartz, B / Sibidanov, A / Simon, F / Sohn, Y-S / Sokolov, A / Starič, M / Steder, M / Stypula, J / Tanida, K / Teramoto, Y / Trabelsi, K / Uchida, M / Uglov, T / Unno, Y / Uno, S / Urquijo, P / Van Hulse, C / Vanhoefer, P / Varner, G / Vinokurova, A / Vossen, A / Wagner, M N / Wang, M-Z / Wang, X L / Watanabe, Y / Williams, K M / Won, E / Yamaoka, J / Yashchenko, S / Zhang, Z P / Zhilich, V / Zhulanov, V / Zupanc, A

    Physical review letters

    2015  Volume 115, Issue 14, Page(s) 142001

    Abstract: ... ηh(b)(1P)]=(2.18±0.11±0.18)×10(-3) and we measure the h(b)(1P) mass M(h(b)(1P))=(9899.3±0.4±1.0)  MeV ... the transition h(b)(1P)→γη(b)(1S), we measure the η(b)(1S) mass M(η(b)(1S))=(9400.7±1.7±1.6)  MeV/c(2 ... the branching fraction B[h(b)(1P)→γη(b)(1S)]=(56±8±4)%. ...

    Abstract Using a sample of 771.6×10(6) ϒϒ(4S) decays collected by the Belle experiment at the KEKB e(+)e(-) collider, we observe, for the first time, the transition ϒ(4S)→ηh(b)(1P) with the branching fraction B[ϒ(4S)→ηh(b)(1P)]=(2.18±0.11±0.18)×10(-3) and we measure the h(b)(1P) mass M(h(b)(1P))=(9899.3±0.4±1.0)  MeV/c(2), corresponding to the hyperfine (HF) splitting ΔM(HF)(1P)=(0.6±0.4±1.0)  MeV/c(2). Using the transition h(b)(1P)→γη(b)(1S), we measure the η(b)(1S) mass M(η(b)(1S))=(9400.7±1.7±1.6)  MeV/c(2), corresponding to ΔM(HF)(1S)=(59.6±1.7±1.6)  MeV/c(2), the η(b)(1S) width Γ(η(b)(1S))=(8(-5)(+6)±5)  MeV/c(2) and the branching fraction B[h(b)(1P)→γη(b)(1S)]=(56±8±4)%.
    Language English
    Publishing date 2015-10-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.115.142001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Evidence for the η(b)(2S) and observation of h(b)(1P)→η(b)(1S)γ and h(b)(2P)→η(b)(1S)γ.

    Mizuk, R / Asner, D M / Bondar, A / Pedlar, T K / Adachi, I / Aihara, H / Arinstein, K / Aulchenko, V / Aushev, T / Aziz, T / Bakich, A M / Bay, A / Belous, K / Bhardwaj, V / Bhuyan, B / Bischofberger, M / Bonvicini, G / Bozek, A / Bračko, M /
    Brodzicka, J / Browder, T E / Chekelian, V / Chen, A / Chen, P / Cheon, B G / Chilikin, K / Chistov, R / Cho, I-S / Cho, K / Choi, S-K / Choi, Y / Dalseno, J / Danilov, M / Doležal, Z / Drásal, Z / Drutskoy, A / Eidelman, S / Epifanov, D / Fast, J E / Gaur, V / Gabyshev, N / Garmash, A / Golob, B / Haba, J / Hara, T / Hayasaka, K / Hayashii, H / Horii, Y / Hoshi, Y / Hou, W-S / Hsiung, Y B / Hyun, H J / Iijima, T / Ishikawa, A / Itoh, R / Iwabuchi, M / Iwasaki, Y / Iwashita, T / Jaegle, I / Julius, T / Kang, J H / Kapusta, P / Kawasaki, T / Kim, H J / Kim, H O / Kim, J H / Kim, K T / Kim, M J / Kim, Y J / Kinoshita, K / Ko, B R / Koblitz, S / Kodyš, P / Korpar, S / Kouzes, R T / Križan, P / Krokovny, P / Kuhr, T / Kumita, T / Kuzmin, A / Kwon, Y-J / Lange, J S / Lee, S-H / Li, J / Libby, J / Liu, C / Liu, Y / Liu, Z Q / Liventsev, D / Louvot, R / Matvienko, D / McOnie, S / Miyabayashi, K / Miyata, H / Mohanty, G B / Mohapatra, D / Moll, A / Muramatsu, N / Mussa, R / Nakao, M / Natkaniec, Z / Ng, C / Nishida, S / Nishimura, K / Nitoh, O / Nozaki, T / Ohshima, T / Okuno, S / Olsen, S L / Onuki, Y / Pakhlov, P / Pakhlova, G / Park, C W / Park, H / Pestotnik, R / Petrič, M / Piilonen, L E / Poluektov, A / Röhrken, M / Sakai, Y / Sandilya, S / Santel, D / Sanuki, T / Sato, Y / Schneider, O / Schwanda, C / Senyo, K / Seon, O / Sevior, M E / Shapkin, M / Shen, C P / Shibata, T-A / Shiu, J-G / Shwartz, B / Sibidanov, A / Simon, F / Smerkol, P / Sohn, Y-S / Sokolov, A / Solovieva, E / Stanič, S / Starič, M / Sumihama, M / Sumiyoshi, T / Tanida, K / Tatishvili, G / Teramoto, Y / Tikhomirov, I / Trabelsi, K / Tsuboyama, T / Uchida, M / Uehara, S / Uglov, T / Unno, Y / Uno, S / Vanhoefer, P / Varner, G / Varvell, K E / Vinokurova, A / Vorobyev, V / Wang, C H / Wang, M-Z / Wang, P / Wang, X L / Watanabe, M / Watanabe, Y / Williams, K M / Won, E / Yabsley, B D / Yamaoka, J / Yamashita, Y / Yuan, C Z / Zhang, Z P / Zhilich, V

    Physical review letters

    2012  Volume 109, Issue 23, Page(s) 232002

    Abstract: We report the first evidence for the η(b)(2S) using the h(b)(2P)→η(b)(2S)γ transition and the first ... observation of the h(b)(1P)→η(b)(1S)γ and h(b)(2P)→η(b)(1S)γ transitions. The mass and width of the η(b)(1S ... 2.8)) MeV/c(2), and Γ(η(b)(1S))=(10.8(-3.7-2.0)(+4.0+4.5)) MeV. We also update the h(b)(1P) and h(b ...

    Abstract We report the first evidence for the η(b)(2S) using the h(b)(2P)→η(b)(2S)γ transition and the first observation of the h(b)(1P)→η(b)(1S)γ and h(b)(2P)→η(b)(1S)γ transitions. The mass and width of the η(b)(1S) and η(b)(2S) are measured to be m(η(b)(1S))=(9402.4±1.5±1.8) MeV/c(2), m(η(b)(2S))=(9999.0±3.5(-1.9)(+2.8)) MeV/c(2), and Γ(η(b)(1S))=(10.8(-3.7-2.0)(+4.0+4.5)) MeV. We also update the h(b)(1P) and h(b)(2P) mass measurements. We use a 133.4 fb(-1) data sample collected at energies near the Υ(5S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider.
    MeSH term(s) Nuclear Physics/methods ; Photons ; Quantum Theory
    Language English
    Publishing date 2012-12-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.109.232002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Iridium(III)-Catalyzed Regioselective B(4)–H Allenylation of o-Carboranes by Ball Milling

    Shin, Seohyun / Um, Kyusik / Ko, Gi Hoon / Han, Gi Uk / Kim, Dongwook / Lee, Phil Ho

    Organic letters. 2022 Apr. 25, v. 24, no. 17

    2022  

    Abstract: We disclose an iridium(III)-catalyzed regioselective B(4)–H allenylation of o-carboranes from o ... temperature reactions, reveal that the B(4)–H allenylation of o-carborane is unique for ball-milling ... method to accomplish regioselective B(4)-allenylation of o-carborane that cannot be realized ...

    Abstract We disclose an iridium(III)-catalyzed regioselective B(4)–H allenylation of o-carboranes from o-carborane acids and propargyl carbonates under ball-milling conditions. This study sheds light on a novel method to accomplish regioselective B(4)-allenylation of o-carborane that cannot be realized through conventional solution-based reactions. Control experiments, including solution, neat, microwave, and high-temperature reactions, reveal that the B(4)–H allenylation of o-carborane is unique for ball-milling conditions.
    Keywords acids ; carbonates ; iridium ; microwave radiation ; microwave treatment ; milling ; regioselectivity ; solutions
    Language English
    Dates of publication 2022-0425
    Size p. 3128-3133.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1523-7052
    DOI 10.1021/acs.orglett.2c00756
    Database NAL-Catalogue (AGRICOLA)

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