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  1. Book ; Online ; E-Book: Handbook of nutraceuticals for clinical use

    Cicero, Arrigo F. G. / Colletti, Alessandro

    2018  

    Author's details Arrigo F.G. Cicero, Alessandro Colletti
    Keywords Pharmacy ; Medicine ; Complementary medicine ; Clinical nutrition
    Subject code 616.2
    Language English
    Size 1 Online-Ressource (VII, 219 Seiten)
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019879788
    ISBN 978-3-319-73642-6 ; 9783319736419 ; 3-319-73642-6 ; 3319736418
    DOI 10.1007/978-3-319-73642-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Correspondence.

    Arrigo, Alessandro / Aragona, Emanuela / Bandello, Francesco

    Retina (Philadelphia, Pa.)

    2022  Volume 42, Issue 10, Page(s) e46

    Language English
    Publishing date 2022-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1724: Show issues Location:
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  3. Article: Retinal Vessel Analysis and Microvascular Abnormalities in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms.

    Roszkowska, Anna Maria / Leanza, Rossana / Aragona, Emanuela / Gargiulo, Ludovica / Alibrandi, Angela / Arrigo, Alessandro / Bottaro, Adele / Barone, Paola / Stagno, Fabio / Allegra, Alessandro

    Journal of clinical medicine

    2024  Volume 13, Issue 8

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13082232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correspondence.

    Arrigo, Alessandro / Pierro, Luisa / Marchese, Alessandro / Bandello, Francesco

    Retina (Philadelphia, Pa.)

    2020  Volume 41, Issue 2, Page(s) e19

    MeSH term(s) Humans ; Retina
    Language English
    Publishing date 2020-07-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000002929
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1724: Show issues Location:
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  5. Article ; Online: Linear streaks associated with retinitis pigmentosa.

    Battaglia Parodi, Maurizio / Arrigo, Alessandro / Aragona, Emanuela / Pina, Adelaide / Bandello, Francesco

    European journal of ophthalmology

    2024  , Page(s) 11206721241232450

    Abstract: Purpose: To describe a phenotypical manifestation characterized by the identification of peripheral linear streaks associated with retinitis pigmentosa (RP).: Methods: Study design is a prospective observational case series. All consecutive patients ... ...

    Abstract Purpose: To describe a phenotypical manifestation characterized by the identification of peripheral linear streaks associated with retinitis pigmentosa (RP).
    Methods: Study design is a prospective observational case series. All consecutive patients affected by RP underwent a complete ophthalmological examination. The diagnosis of peripheral linear streaks was based on the identification of curvilinear atrophic streaks in the periphery of the retina.
    Results: Overall, six out of 140 patients (4.2%) were affected by peripheral linear streaks associated with RP. A single patient showed also punched out chorioretinal lesions at the posterior pole, with macular neovascularization development over the follow-up, treated with ranibizumab injections.
    Conclusions: RP phenotypical manifestation characterized by peripheral linear streaks is infrequent and may provide additional evidence to support the contribution of inflammation in the pathogenesis of RP.
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721241232450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3342: Show issues Location:
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  6. Article ; Online: Conjunctival vessel density analysis as a marker of inflammation in dry eye disease.

    Aragona, Emanuela / Arrigo, Alessandro / Modorati, Giulio / Berchicci, Luigi / Bandello, Francesco / Miserocchi, Elisabetta

    The ocular surface

    2023  Volume 29, Page(s) 398–400

    MeSH term(s) Humans ; Dry Eye Syndromes/diagnosis ; Conjunctiva ; Inflammation
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Letter
    ZDB-ID 2208578-6
    ISSN 1937-5913 ; 1542-0124
    ISSN (online) 1937-5913
    ISSN 1542-0124
    DOI 10.1016/j.jtos.2023.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6458: Show issues Location:
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  7. Article: Molecular Features of Classic Retinal Drugs, Retinal Therapeutic Targets and Emerging Treatments.

    Arrigo, Alessandro / Bandello, Francesco

    Pharmaceutics

    2021  Volume 13, Issue 7

    Abstract: The management of exudative retinal diseases underwent a revolution due to the introduction of intravitreal treatments. There are two main classes of intravitreal drugs, namely anti-vascular endothelial growth factors (anti-VEGF) and corticosteroids ... ...

    Abstract The management of exudative retinal diseases underwent a revolution due to the introduction of intravitreal treatments. There are two main classes of intravitreal drugs, namely anti-vascular endothelial growth factors (anti-VEGF) and corticosteroids molecules. The clinical course and the outcome of retinal diseases radically changed thanks to the efficacy of these molecules in determining the regression of the exudation and the restoration of the macular profile. In this review, we described the molecular features of classic retinal drugs, highlighting the main therapeutic targets, and we provided an overview of new emerging molecules. We performed a systematic review of the current literature available in the MEDLINE library, focusing on current intravitreal molecules and on new emerging therapies. The anti-VEGF molecules include Bevacizumab, Pegaptanib, Ranibizumab, Aflibercept, Conbercept, Brolucizumab, Abicipar-pegol and Faricimab. The corticosteroids approach is mainly based on the employment of triamcinolone acetonide, dexamethasone and fluocinolone acetonide molecules. Many clinical trials and real-life reports demonstrated their efficacy in exudative retinal diseases, highlighting differences in terms of molecular targeting and pharmacologic profiles. Furthermore, several new molecules are currently under investigation. Intravitreal drugs focus their activity on a wide range of therapeutic targets and are safe and efficacy in managing retinal diseases.
    Language English
    Publishing date 2021-07-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13071102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Retinal vein occlusion: drug targets and therapeutic implications.

    Arrigo, Alessandro / Bandello, Francesco

    Expert opinion on therapeutic targets

    2021  Volume 25, Issue 10, Page(s) 847–864

    Abstract: Introduction: The pathogenesis of retinal vein occlusion (RVO) is extremely complex and includes several mediators. These mediators represent potential drug targets that can be used in the development of intravitreal drugs.: Areas covered: PubMed/ ... ...

    Abstract Introduction: The pathogenesis of retinal vein occlusion (RVO) is extremely complex and includes several mediators. These mediators represent potential drug targets that can be used in the development of intravitreal drugs.
    Areas covered: PubMed/MEDLINE databases were accessed between April-May 2021 to find the most relevant scientific papers regarding drug targets and therapeutic implications in RVO, focusing on current therapeutic options and potential cornerstones of future advances in treatment.
    Expert opinion: Before the introduction of intravitreal therapies, the visual outcome following a diagnosis of RVO was extremely poor. Anti-VEGF and corticosteroid treatments have radically changed RVO prognosis, helping to preserve patients' visual function and their quality of life. According to current clinical data, anti-VEGF and corticosteroid drugs are associated with both pros and cons; the present recommendation is to employ anti-VEGF molecules as a first-line treatment. Advances in our understanding of the biomolecular characteristics of RVO offer a solid basis for the development of new therapeutic targets and treatments.
    MeSH term(s) Angiogenesis Inhibitors/pharmacology ; Angiogenesis Inhibitors/therapeutic use ; Humans ; Pharmaceutical Preparations ; Quality of Life ; Retinal Vein Occlusion/complications ; Retinal Vein Occlusion/diagnosis ; Retinal Vein Occlusion/drug therapy ; Visual Acuity
    Chemical Substances Angiogenesis Inhibitors ; Pharmaceutical Preparations
    Language English
    Publishing date 2021-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2055208-7
    ISSN 1744-7631 ; 1472-8222
    ISSN (online) 1744-7631
    ISSN 1472-8222
    DOI 10.1080/14728222.2021.2005026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5244: Show issues Location:
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  9. Article ; Online: The Possible Role of Probiotic Supplementation in Inflammation

    Alessandro Colletti / Marzia Pellizzato / Arrigo Francesco Cicero

    Microorganisms, Vol 11, Iss 2160, p

    A Narrative Review

    2023  Volume 2160

    Abstract: The fine balance between symbiotic and potentially opportunistic and/or pathogenic microorganisms can undergo quantitative alterations, which, when associated with low intestinal biodiversity, could be responsible for the development of gut inflammation ... ...

    Abstract The fine balance between symbiotic and potentially opportunistic and/or pathogenic microorganisms can undergo quantitative alterations, which, when associated with low intestinal biodiversity, could be responsible for the development of gut inflammation and the so-called “intestinal dysbiosis”. This condition is characterized by the disbalance of a fine synergistic mechanism involving the mucosal barrier, the intestinal neuroendocrine system, and the immune system that results in an acute inflammatory response induced by different causes, including viral or bacterial infections of the digestive tract. More frequently, however, dysbiosis is induced slowly and subtly by subliminal causal factors, resulting in a chronic condition related to different diseases affecting the digestive tract and other organs and apparatuses. Studies on animal models, together with studies on humans, highlight the significant role of the gut microbiota and microbiome in the occurrence of inflammatory conditions such as metabolic syndrome and cardiovascular diseases (CVDs); neurodegenerative, urologic, skin, liver, and kidney pathologies; and premature aging. The blood translocation of bacterial fragments has been found to be one of the processes linked to gut dysbiosis and responsible for the possible occurrence of “metabolic endotoxemia” and systemic inflammation, associated with an increased risk of oxidative stress and related diseases. In this context, supplementation with different probiotic strains has been shown to restore gut eubiosis, especially if administered in long-term treatments. The aim of this review is to describe the anti-inflammatory effects of specific probiotic strains observed in clinical trials and the respective indications, highlighting the differences in efficacy depending on strain, formulation, time and duration of treatment, and dosage used.
    Keywords probiotics ; inflammation ; aging ; oxidative stress ; urinary tract infections ; cardiovascular disease ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Smartphone Eye Examination: Artificial Intelligence and Telemedicine.

    Vilela, Manuel Augusto Pereira / Arrigo, Alessandro / Parodi, Maurizio Battaglia / da Silva Mengue, Carolina

    Telemedicine journal and e-health : the official journal of the American Telemedicine Association

    2023  Volume 30, Issue 2, Page(s) 341–353

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Artificial Intelligence ; Smartphone ; Reproducibility of Results ; Diabetic Retinopathy/diagnosis ; Telemedicine/methods ; Blindness
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2035659-6
    ISSN 1556-3669 ; 1530-5627
    ISSN (online) 1556-3669
    ISSN 1530-5627
    DOI 10.1089/tmj.2023.0041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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