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  1. Article ; Online: Genetic Background as a Missing Factor in COVID-19 Severity

    Alireza Tahamtan

    Journal of Clinical and Basic Research, Vol 4, Iss 3, Pp 1-

    2020  Volume 2

    Abstract: The clinical outcome of coronavirus disease 2019 (COVID-19) varies considerably from one individual to another and severe illness occurs only in a minority of cases. Evidence supports the role of genetic background alongside host, viral and environmental ...

    Abstract The clinical outcome of coronavirus disease 2019 (COVID-19) varies considerably from one individual to another and severe illness occurs only in a minority of cases. Evidence supports the role of genetic background alongside host, viral and environmental factors for COVID-19 severity. It seems that host genetic background affects the balance of immune responses during SARS-CoV-2 infection, leading to different clinical courses of the disease
    Keywords covid-19 ; sars-cov-2 ; genetic background ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Golestan University Of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Editorial: miRNAs and inflammation: from biogenesis to therapeutic option.

    Tahamtan, Alireza / Samadizadeh, Saeed / Salimi, Vahid / Natarelli, Lucia / Nakstad, Britt

    Frontiers in immunology

    2023  Volume 14, Page(s) 1296589

    MeSH term(s) Humans ; MicroRNAs/genetics ; Inflammation/genetics ; Gene Expression Regulation
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2023-10-03
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1296589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 diagnosis: lessons to learn and hints for preparedness.

    Samadizadeh, Saeed / Nakstad, Britt / Jamalpoor, Zahra / Tahamtan, Alireza

    Expert review of molecular diagnostics

    2022  Volume 22, Issue 9, Page(s) 851–853

    MeSH term(s) Humans ; COVID-19/diagnosis ; SARS-CoV-2 ; COVID-19 Testing ; Reverse Transcriptase Polymerase Chain Reaction
    Language English
    Publishing date 2022-10-08
    Publishing country England
    Document type Editorial
    ZDB-ID 2112530-2
    ISSN 1744-8352 ; 1473-7159
    ISSN (online) 1744-8352
    ISSN 1473-7159
    DOI 10.1080/14737159.2022.2132852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Real-time RT-PCR in COVID-19 detection: issues affecting the results.

    Tahamtan, Alireza / Ardebili, Abdollah

    Expert review of molecular diagnostics

    2020  Volume 20, Issue 5, Page(s) 453–454

    MeSH term(s) Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Diagnostic Errors ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; Real-Time Polymerase Chain Reaction/methods ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Chemical Substances COVID-19 Vaccines ; Covid-19 aAPC vaccine
    Keywords covid19
    Language English
    Publishing date 2020-04-22
    Publishing country England
    Document type Editorial
    ZDB-ID 2112530-2
    ISSN 1744-8352 ; 1473-7159
    ISSN (online) 1744-8352
    ISSN 1473-7159
    DOI 10.1080/14737159.2020.1757437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prevalence of CCR5 Delta 32 Genetic Variant in the Turkmen Population of Golestan Province, Northeast of Iran.

    Norasi, Elmira / Rastegar, Mostafa / Hosseini, Seyedeh Delafruz / Aghcheli, Bahman / Tahamtan, Alireza

    BioMed research international

    2023  Volume 2023, Page(s) 8823863

    Abstract: The 32 bp deletion in the chemokine receptor (C-C motif) 5 gene ( ... ...

    Abstract The 32 bp deletion in the chemokine receptor (C-C motif) 5 gene (CCR5
    MeSH term(s) Adult ; Female ; Humans ; Male ; Alleles ; Autoimmune Diseases ; Genotype ; Iran/epidemiology ; Prevalence ; Receptors, CCR5/genetics ; Young Adult ; Middle Aged
    Chemical Substances CCR5 protein, human ; Receptors, CCR5
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2023/8823863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cross-reactivity between

    Asgari, Negar / Ghaemi, Ezzat Allah / Naeimi, Mohammad Hasan / Tahamtan, Alireza / Sechi, Leonardo Antonio / Zamani, Samin

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e22137

    Abstract: Background: The etiology of Multiple sclerosis (MS) is complicated and can be affected by several environmental factors, such as : Materials and methods: This case-control study examined 200 blood samples (100 MS patients and 100 HCs) to search for ... ...

    Abstract Background: The etiology of Multiple sclerosis (MS) is complicated and can be affected by several environmental factors, such as
    Materials and methods: This case-control study examined 200 blood samples (100 MS patients and 100 HCs) to search for the MAP-specific IS900 gene. In addition, ELISA was conducted to determine the humoral response against MAP_4027
    Results: The frequency of MAP detection based on the molecular method in MS patients and HCs was 48 % and 13 %, respectively (
    Conclusion: Our research revealed a significant association between MAP and MS, highlighting the possible role of MAP as an important infection trigger factor of MS. It is hypothesized that cross-reactivity between MAP4027 and IRF5 may dysregulate immune homeostasis.
    Language English
    Publishing date 2023-11-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Epidemiology and clinical features of respiratory syncytial virus (RSV) infection in hospitalized children during the COVID-19 pandemic in Gorgan, Iran.

    Ramzali, Mahnaz / Salimi, Vahid / Cheraghali, Fatemeh / Hosseini, Seyedeh Delafruz / Yasaghi, Mohammad / Samadizadeh, Saeed / Rastegar, Mostafa / Nakstad, Britt / Tahamtan, Alireza

    Health science reports

    2024  Volume 7, Issue 1, Page(s) e1787

    Abstract: Background and aims: Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection in infants and young children. Given the altered circulation patterns of respiratory viruses during the coronavirus disease pandemic-2019 (COVID-19), ...

    Abstract Background and aims: Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection in infants and young children. Given the altered circulation patterns of respiratory viruses during the coronavirus disease pandemic-2019 (COVID-19), the study aimed to evaluate epidemiology and clinical features of RSV infections in hospitalized children during the COVID-19 pandemic in Gorgan, northeastern Iran. Molecular epidemiology studies on respiratory viral infections are necessary to monitor circulating viruses, disease severity, and clinical symptoms, in addition to early warning of new outbreaks.
    Methods: Overall, 411 respiratory swab samples from hospitalized children from October 2021 to March 2022 were collected at Taleghani Children's Hospital, Gorgan, Iran. The incidence of RSV, as well as the circulating subgroups and genotypes, were investigated and confirmed using PCR methods. Additionally, all samples tested for severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) and influenza, and demographic and clinical data were analyzed using SPSS software.
    Results: The share of RSV, SARS-CoV-2, and influenza among hospitalized children with acute lower respiratory infections (ALRI) were 27%, 16.5%, and 4.1%, respectively. The RSV subgroup A (genotype ON1) was dominant over subgroup B (genotype BA9), with more severe clinical symptoms. Compared with the prepandemic era there were high numbers of hospitalized SARS-CoV-2 positive children and low numbers of other respiratory viruses. Despite this, the prevalence of ALRI-related RSV-disease among hospitalized children in our specialized pediatric center was higher than COVID-19 disease in the same cohort.
    Conclusions: Studying the epidemiology of respiratory viruses and determining the circulating strains can contribute to effective infection control and treatment strategies.
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.1787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Opioids/cannabinoids as a potential therapeutic approach in COVID-19 patients.

    Tahamtan, Alireza / Tavakoli-Yaraki, Masoumeh / Salimi, Vahid

    Expert review of respiratory medicine

    2020  Volume 14, Issue 10, Page(s) 965–967

    Keywords covid19
    Language English
    Publishing date 2020-06-30
    Publishing country England
    Document type Editorial
    ZDB-ID 2479146-5
    ISSN 1747-6356 ; 1747-6348
    ISSN (online) 1747-6356
    ISSN 1747-6348
    DOI 10.1080/17476348.2020.1787836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6963: Show issues Location:
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  10. Article ; Online: Transcription activator-like effector nuclease (TALEN) as a promising diagnostic approach for COVID-19.

    Behboudi, Emad / Zeynali, Parisa / Hamidi-Sofiani, Vahideh / Nakstad, Britt / Tahamtan, Alireza

    Expert review of molecular diagnostics

    2022  Volume 22, Issue 4, Page(s) 395–397

    MeSH term(s) COVID-19/diagnosis ; Humans ; Transcription Activator-Like Effector Nucleases ; Transcription Activator-Like Effectors
    Chemical Substances Transcription Activator-Like Effectors ; Transcription Activator-Like Effector Nucleases (EC 3.1.-)
    Language English
    Publishing date 2022-04-13
    Publishing country England
    Document type Editorial
    ZDB-ID 2112530-2
    ISSN 1744-8352 ; 1473-7159
    ISSN (online) 1744-8352
    ISSN 1473-7159
    DOI 10.1080/14737159.2022.2065194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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