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  1. Article ; Online: The Case for Inclusion of a Lipid Panel in the Standard Precatheterization Laboratory Blood Draw-Stating What Should Be Obvious.

    Ranard, Lauren S / Duffy, Eamon Y / Kirtane, Ajay J

    JAMA cardiology

    2023  Volume 8, Issue 7, Page(s) 629–630

    MeSH term(s) Humans ; Lipids/blood ; Diagnostic Tests, Routine ; Catheterization
    Chemical Substances Lipids
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2023.1287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Primary and Secondary Prevention of Cardiovascular Disease in the Era of the Coronavirus Pandemic.

    Duffy, Eamon Y / Cainzos-Achirica, Miguel / Michos, Erin D

    Circulation

    2020  Volume 141, Issue 24, Page(s) 1943–1945

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Healthy Lifestyle ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Primary Prevention/methods ; Primary Prevention/trends ; SARS-CoV-2 ; Secondary Prevention/methods ; Secondary Prevention/trends
    Keywords covid19
    Language English
    Publishing date 2020-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.047194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Protecting Our Youth: Support Policy to Combat Health Disparities Fueled by Targeted Food Advertising.

    Fischer, Nicole M / Duffy, Eamon Y / Michos, Erin D

    Journal of the American Heart Association

    2020  Volume 10, Issue 1, Page(s) e018900

    MeSH term(s) Adolescent ; African Continental Ancestry Group/statistics & numerical data ; Beverages/standards ; Child ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/ethnology ; Diabetes Mellitus, Type 2/prevention & control ; Feeding Behavior/ethnology ; Food/standards ; Health Status Disparities ; Hispanic Americans/statistics & numerical data ; Humans ; Marketing ; Needs Assessment ; Pediatric Obesity/diagnosis ; Pediatric Obesity/ethnology ; Pediatric Obesity/prevention & control ; Preventive Health Services/organization & administration ; United States/epidemiology
    Language English
    Publishing date 2020-12-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.120.018900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID and Cardiovascular Disease: What We Know in 2021.

    Chilazi, Michael / Duffy, Eamon Y / Thakkar, Aarti / Michos, Erin D

    Current atherosclerosis reports

    2021  Volume 23, Issue 7, Page(s) 37

    Abstract: Purpose of review: Coronavirus disease 2019 (COVID-19) has been the cause of significant global morbidity and mortality. Here, we review the literature to date of the short-term and long-term consequences of Severe Acute Respiratory Syndrome Coronavirus- ...

    Abstract Purpose of review: Coronavirus disease 2019 (COVID-19) has been the cause of significant global morbidity and mortality. Here, we review the literature to date of the short-term and long-term consequences of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection on the heart.
    Recent findings: Early case reports described a spectrum of cardiovascular manifestations of COVID-19, including myocarditis, stress cardiomyopathy, myocardial infarction, and arrhythmia. However, in most cases, myocardial injury in COVID-19 appears to be predominantly mediated by the severity of critical illness rather than direct injury to myocardium from viral particles. While cardiac magnetic resonance imaging remains a powerful tool for diagnosing acute myocarditis, it should be used judiciously in light of low baseline prevalence of myocarditis. Guiding an athletic patient through return to play (RTP) after COVID-19 infection is a challenging process. More recent data show RTP has been a safe endeavor using a screening protocol. "Long COVID" or post-acute sequelae of SARS-CoV-2 infection has also been described. The reported symptoms span a large breadth of cardiopulmonary and neurologic complaints including fatigue, palpitations, chest pain, breathlessness, brain fog, and dysautonomia including postural tachycardia syndrome (POTS). Management of POTS/dysautonomia primarily centers on education, exercise, and salt and fluid repletion. Our understanding of the impact of COVID-19 on the cardiovascular system is constantly evolving. As we enter a new age of survivorship, additional research is needed to catalogue the burden of persistent cardiopulmonary symptoms. Research is also needed to learn how acute management may alter the likelihood and prevalence of this chronic syndrome.
    MeSH term(s) Athletes ; COVID-19/blood ; COVID-19/complications ; COVID-19/rehabilitation ; COVID-19/virology ; Cardiovascular Diseases/diagnostic imaging ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/virology ; Humans ; Magnetic Resonance Imaging/methods ; Prognosis ; Return to Sport ; SARS-CoV-2 ; Severity of Illness Index ; Troponin/blood
    Chemical Substances Troponin
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2057369-8
    ISSN 1534-6242 ; 1523-3804
    ISSN (online) 1534-6242
    ISSN 1523-3804
    DOI 10.1007/s11883-021-00935-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Electrocardiographic Findings in Female Professional Basketball Athletes.

    Lander, Bradley S / Duffy, Eamon Y / Hennessey, Jessica A / Tolani, Sonia / Patel, Nidhi / Bohnen, Michael S / Hsu, Jeffrey J / Danielian, Alfred / Shah, Ankit B / Goolsby, Marci / Martinez, Matthew W / Phelan, Dermot / Engel, David J

    JAMA cardiology

    2024  Volume 9, Issue 5, Page(s) 475–479

    Abstract: Importance: Previous studies of professional basketball athletes have characterized manifestations of athletic remodeling by echocardiography and electrocardiography (ECG) in males and echocardiography in females. There is a paucity of female, ... ...

    Abstract Importance: Previous studies of professional basketball athletes have characterized manifestations of athletic remodeling by echocardiography and electrocardiography (ECG) in males and echocardiography in females. There is a paucity of female, basketball-specific ECG data.
    Objective: To generate reference range ECG data for female professional basketball athletes.
    Design, setting, and participants: This is a cross-sectional study of ECGs performed on female professional basketball athletes. The Women's National Basketball Association mandates annual preseason ECGs and echocardiograms for each athlete and has partnered with Columbia University Irving Medical Center to annually review these studies. Data for this study were collected during preseason ECG and echocardiography cardiac screening between April and May 2022. Data analysis was performed between February and July 2023.
    Exposure: Athlete ECGs and echocardiograms were sent to Columbia University Irving Medical Center for core lab analysis.
    Main outcomes and measures: Quantitative ECG variables were measured. ECG data were qualitatively analyzed for training-related and abnormal findings using the International Recommendations for Electrocardiographic Interpretation in Athletes. Findings from ECGs were compared with corresponding echocardiographic data.
    Results: There were a total of 173 athletes (mean [SD] age 26.5 [4.1] years; mean [SD] height, 183.4 [9.1] cm; mean [SD] body surface area, 2.0 [0.2] m2), including 129 Black athletes (74.5%) and 40 White athletes (23.1%). By international criteria, 136 athletes (78.6%) had training-related ECG changes and 8 athletes (4.6%) had abnormal ECG findings. Among athletes with at least 1 training-related ECG finding, left ventricular structural adaptations associated with athletic remodeling were present in 64 athletes (47.1%). Increased relative wall thickness, reflecting concentric left ventricular geometry, was more prevalent in athletes with the repolarization variant demonstrating convex ST elevation combined with T-wave inversions in leads V1 to V4 (6 of 12 athletes [50.0%]) than in athletes with early repolarization (5 of 42 athletes [11.9%]) (odds ratio, 7.40; 95% CI, 1.71-32.09; P = .01). Abnormal ECG findings included T-wave inversions (3 athletes [1.7%]), Q waves (2 athletes [1.2%]), prolonged QTc interval (2 athletes [1.2%]), and frequent premature ventricular contractions (1 athlete [0.6%]).
    Conclusions and relevance: This cross-sectional study provides reference ECG data for elite female basketball athletes. International criteria-defined training-related findings were common, whereas abnormal ECG findings were rare in this athlete group. These reference data may assist basketball programs and health care professionals using ECGs in screening for female athletes and may be used as a stimulus for future female-specific ECG inquiries.
    MeSH term(s) Humans ; Basketball/physiology ; Electrocardiography ; Female ; Cross-Sectional Studies ; Adult ; Athletes ; Echocardiography ; Young Adult ; Reference Values
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2024.0207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Communication approaches to enhance patient motivation and adherence in cardiovascular disease prevention.

    Duffy, Eamon Y / Ashen, Dominique / Blumenthal, Roger S / Davis, Dorothy M / Gulati, Martha / Blaha, Michael J / Michos, Erin D / Nasir, Khurram / Cainzos-Achirica, Miguel

    Clinical cardiology

    2021  Volume 44, Issue 9, Page(s) 1199–1207

    Abstract: Preventive cardiology visits have traditionally focused on educating patients about disease risk factors and the need to avoid and manage them through lifestyle changes and medications. However, long-term patient adherence to the recommended ... ...

    Abstract Preventive cardiology visits have traditionally focused on educating patients about disease risk factors and the need to avoid and manage them through lifestyle changes and medications. However, long-term patient adherence to the recommended interventions remains a key unmet need. In this review we discuss the rationale and potential benefits of a paradigm shift in the clinician-patient encounter, from focusing on education to explicitly discussing key drivers of individual motivation. This includes the emotional, psychological, and economic mindset that patients bring to their health decisions. Five communication approaches are proposed that progress clinician-patient preventive cardiology conversations, from provision of information to addressing values and priorities such as common health concerns, love for the family, desire of social recognition, financial stressors, and desire to receive personalized advice. Although further research is needed, these approaches may facilitate developing deeper, more effective bonds with patients, enhance adherence to recommendations and ultimately, improve cardiovascular outcomes.
    MeSH term(s) Cardiology ; Cardiovascular Diseases/prevention & control ; Communication ; Humans ; Motivation ; Patient Compliance
    Language English
    Publishing date 2021-08-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.23555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Opportunities to improve cardiovascular health in the new American workplace

    Eamon Y. Duffy / Pranoti G. Hiremath / Pablo Martinez-Amezcua / Richard Safeer / Jennifer A. Schrack / Michael J. Blaha / Erin D. Michos / Roger S. Blumenthal / Seth S. Martin / Miguel Cainzos-Achirica

    American Journal of Preventive Cardiology, Vol 5, Iss , Pp 100136- (2021)

    2021  

    Abstract: Adult working-class Americans spend on average 50% of their workday awake time at their jobs. The vast majority of these jobs involve mostly physically inactive tasks and frequent exposure to unhealthy food options. Traditionally, the workplace has been ... ...

    Abstract Adult working-class Americans spend on average 50% of their workday awake time at their jobs. The vast majority of these jobs involve mostly physically inactive tasks and frequent exposure to unhealthy food options. Traditionally, the workplace has been a challenging environment for cardiovascular prevention, where cardiovascular guidelines have had limited implementation. Despite the impact that unhealthy lifestyles at the workplace may have on the cardiovascular health of U.S. workers, there is currently no policy in place aimed at improving this. In this review, we discuss recent evidence on the prevalence of physical inactivity among Americans, with a special focus on the time spent at the workplace; and the invaluable opportunity that workplace-based lifestyle interventions may represent for improving the prevention of cardiovascular disease. We describe the current regulatory context, the key stakeholders involved, and present specific, guideline-inspired initiatives to be considered by both Congress and employers to improve the “cardiovascular safety” of US jobs. Additionally, we discuss how the COVID-19 pandemic has forever altered the workplace, and what lessons can be taken from this experience and applied to cardiovascular disease prevention in the new American workplace. For many Americans, long sitting hours at their job represent a risk to their cardiovascular health. We discuss how a paradigm shift in how we approach cardiovascular health, from focusing on leisure time to also focusing on work time, may help curtail the epidemic of cardiovascular disease in this country.
    Keywords Cardiovascular disease ; Diets ; Job safety ; Physical activity ; Occupational health ; Prevention ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Opportunities to improve cardiovascular health in the new American workplace.

    Duffy, Eamon Y / Hiremath, Pranoti G / Martinez-Amezcua, Pablo / Safeer, Richard / Schrack, Jennifer A / Blaha, Michael J / Michos, Erin D / Blumenthal, Roger S / Martin, Seth S / Cainzos-Achirica, Miguel

    American journal of preventive cardiology

    2020  Volume 5, Page(s) 100136

    Abstract: Adult working-class Americans spend on average 50% of their workday awake time at their jobs. The vast majority of these jobs involve mostly physically inactive tasks and frequent exposure to unhealthy food options. Traditionally, the workplace has been ... ...

    Abstract Adult working-class Americans spend on average 50% of their workday awake time at their jobs. The vast majority of these jobs involve mostly physically inactive tasks and frequent exposure to unhealthy food options. Traditionally, the workplace has been a challenging environment for cardiovascular prevention, where cardiovascular guidelines have had limited implementation. Despite the impact that unhealthy lifestyles at the workplace may have on the cardiovascular health of U.S. workers, there is currently no policy in place aimed at improving this. In this review, we discuss recent evidence on the prevalence of physical inactivity among Americans, with a special focus on the time spent at the workplace; and the invaluable opportunity that workplace-based lifestyle interventions may represent for improving the prevention of cardiovascular disease. We describe the current regulatory context, the key stakeholders involved, and present specific, guideline-inspired initiatives to be considered by both Congress and employers to improve the "cardiovascular safety" of US jobs. Additionally, we discuss how the COVID-19 pandemic has forever altered the workplace, and what lessons can be taken from this experience and applied to cardiovascular disease prevention in the new American workplace. For many Americans, long sitting hours at their job represent a risk to their cardiovascular health. We discuss how a paradigm shift in how we approach cardiovascular health, from focusing on leisure time to also focusing on work time, may help curtail the epidemic of cardiovascular disease in this country.
    Language English
    Publishing date 2020-12-08
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2666-6677
    ISSN (online) 2666-6677
    DOI 10.1016/j.ajpc.2020.100136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Randomized Trial of Nafamostat for Covid-19.

    Morpeth, Susan C / Venkatesh, Balasubramanian / Totterdell, James A / McPhee, Grace M / Mahar, Robert K / Jones, Mark / Bandara, Methma / Barina, Lauren A / Basnet, Bhupendra K / Bowen, Asha C / Burke, Andrew J / Cochrane, Belinda / Denholm, Justin T / Dhungana, Ashesh / Dore, Gregory J / Dotel, Ravindra / Duffy, Eamon / Dummer, Jack / Foo, Hong /
    Gilbey, Timothy L / Hammond, Naomi E / Hudson, Bernard J / Jha, Vivekanand / Jevaji, Purnima R / John, Oommen / Joshi, Rajesh / Kang, Gagandeep / Kaur, Baldeep / Kim, Seungtaek / Das, Santa Kumar / Lau, Jillian S Y / Littleford, Roberta / Marsh, Julie A / Marschner, Ian C / Matthews, Gail / Maze, Michael J / McArthur, Colin J / McFadyen, James D / McMahon, James H / McQuilten, Zoe K / Molton, James / Mora, Jocelyn M / Mudaliar, Vijaybabu / Nguyen, Vi / O'Sullivan, Matthew V N / Pant, Suman / Park, Jaha E / Paterson, David L / Price, David J / Raymond, Nigel / Rees, Megan A / Robinson, James O / Rogers, Benjamin A / Ryu, Wang-Shick / Sasadeusz, Joe / Shum, Omar / Snelling, Thomas L / Sommerville, Christine / Trask, Nanette / Lewin, Sharon R / Hills, Thomas E / Davis, Joshua S / Roberts, Jason A / Tong, Steven Y C

    NEJM evidence

    2023  Volume 2, Issue 11, Page(s) EVIDoa2300132

    Abstract: A Randomized Trial of Nafamostat for Covid-19Nafamostat mesylate is a potent in vitro antiviral that inhibits the host transmembrane protease serine 2 enzyme used by SARS-CoV-2 for cell entry. Morpeth et al report the results of an open-label randomized ... ...

    Abstract A Randomized Trial of Nafamostat for Covid-19Nafamostat mesylate is a potent in vitro antiviral that inhibits the host transmembrane protease serine 2 enzyme used by SARS-CoV-2 for cell entry. Morpeth et al report the results of an open-label randomized clinical trial of nafamostat for noncritically ill patients with Covid-19.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Guanidines/pharmacology ; Benzamidines
    Chemical Substances nafamostat (Y25LQ0H97D) ; Guanidines ; Benzamidines
    Language English
    Publishing date 2023-10-18
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 2766-5526
    ISSN (online) 2766-5526
    DOI 10.1056/EVIDoa2300132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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