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  1. Article ; Online: Impact of Digital Technology on Eye Diseases During COVID-19.

    Wan, Kelvin H / Jonas, Jost B

    Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

    2022  Volume 11, Issue 5, Page(s) 401–402

    MeSH term(s) COVID-19/epidemiology ; Digital Technology ; Eye Diseases/epidemiology ; Eye Diseases/therapy ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2756329-7
    ISSN 2162-0989 ; 2162-0989
    ISSN (online) 2162-0989
    ISSN 2162-0989
    DOI 10.1097/APO.0000000000000560
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  2. Article ; Online: Comment on: Quality of Life in Primary Open-Angle Glaucoma and Cataract: An Analysis of VFQ-25 and OSDI from the iStent inject® Pivotal Trial.

    Wan, Kelvin H / Tham, Clement C

    American journal of ophthalmology

    2021  Volume 234, Page(s) 327–328

    MeSH term(s) Cataract/complications ; Glaucoma Drainage Implants ; Glaucoma, Open-Angle/diagnosis ; Humans ; Quality of Life
    Language English
    Publishing date 2021-10-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2021.05.033
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  3. Article ; Online: Coronavirus Disease 2019 Pandemic and Infodemic: Separating the Signal From the Noise.

    Wan, Kelvin H / Radke, Nishant Vijay / Wong, Raymond L M / Jonas, Jost B

    Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

    2023  Volume 12, Issue 6, Page(s) 507–508

    MeSH term(s) Humans ; COVID-19/epidemiology ; Infodemic ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2023-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2756329-7
    ISSN 2162-0989 ; 2162-0989
    ISSN (online) 2162-0989
    ISSN 2162-0989
    DOI 10.1097/APO.0000000000000649
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  4. Article ; Online: Comment on: Corneal Epithelial Thickness Measured Using AS-OCT as a Diagnostic Parameter for Limbal Stem Cell Deficiency.

    Wan, Kelvin H / Kua, Wee Nie

    American journal of ophthalmology

    2020  Volume 220, Page(s) 218

    MeSH term(s) Corneal Diseases/diagnosis ; Humans ; Limbus Corneae/diagnostic imaging ; Scleral Diseases ; Stem Cells ; Tomography, Optical Coherence
    Language English
    Publishing date 2020-08-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2020.05.044
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  5. Article ; Online: Toric intraocular lenses for astigmatism correction after keratoplasty in phakic and pseudophakic eyes.

    Wan, Kelvin H / Chang, John S M / Jhanji, Vishal

    Journal of cataract and refractive surgery

    2022  Volume 48, Issue 9, Page(s) 1078–1087

    Abstract: Residual astigmatism and anisometropia significantly affect patients' vision and quality of life even in clear grafts after corneal transplant. This study reviewed and summarized the role of toric intraocular lenses (IOLs) in phakic and pseudophakic eyes ...

    Abstract Residual astigmatism and anisometropia significantly affect patients' vision and quality of life even in clear grafts after corneal transplant. This study reviewed and summarized the role of toric intraocular lenses (IOLs) in phakic and pseudophakic eyes after penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty in correcting residual astigmatism. 342 eyes from 20 studies with iris-clipped toric IOL, ciliary sulcus toric implantable collamer lens, piggyback sulcus toric IOL, or posterior chamber toric IOL implantations for phakic, pseudophakic, or eyes undergoing cataract surgery after keratoplasty were included. Visual, refractive, and predictability outcomes were encouraging. Secondary realignment rate and complications were low. Endothelial cell loss secondary to phakic toric IOLs might be a concern over the long-term, particularly in iris-clipped IOLs in PKP eyes. Toric IOLs represent a viable option in the treatment of residual astigmatism in postkeratoplasty eyes, resulting in improved visual acuity and reduced anisometropia.
    MeSH term(s) Anisometropia ; Astigmatism ; Corneal Transplantation ; Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Phakic Intraocular Lenses ; Quality of Life ; Refraction, Ocular
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/j.jcrs.0000000000000907
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  6. Article ; Online: Risk of SARS-CoV-2 Transmission via Corneal Transplant From Donors With COVID-19.

    Wan, Kelvin H / Chow, Vanissa W S / Lam, Dennis S C

    JAMA ophthalmology

    2021  Volume 139, Issue 8, Page(s) 922–923

    MeSH term(s) COVID-19 ; Corneal Transplantation ; Humans ; SARS-CoV-2 ; Tissue Donors
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2021.2148
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  7. Article ; Online: Conjunctival Findings in Patients With Coronavirus Disease 2019.

    Wan, Kelvin H / Huang, Suber S / Lam, Dennis S C

    JAMA ophthalmology

    2020  Volume 139, Issue 2, Page(s) 254–255

    MeSH term(s) COVID-19 ; China ; Conjunctivitis, Viral ; Humans ; RNA, Viral ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2020-09-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2020.5819
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  8. Article ; Online: Combined accelerated collagen crosslinking and sub-Bowman's keratomileusis in high myopic eyes: a comparison between total ultraviolet energy dose.

    Wan, Kelvin H / Chan, Tommy Cy / Kwok, Peter Sk / Ng, Alex Lk

    Seminars in ophthalmology

    2022  Volume 37, Issue 5, Page(s) 676–681

    Abstract: Aim: To compare the safety, efficacy, and predictability outcomes of combined sub-Bowman's keratomileusis (thin flap laser in situ keratomileusis [LASIK]) and accelerated crosslinking (CXL) using two different irradiation durations.: Methods: A ... ...

    Abstract Aim: To compare the safety, efficacy, and predictability outcomes of combined sub-Bowman's keratomileusis (thin flap laser in situ keratomileusis [LASIK]) and accelerated crosslinking (CXL) using two different irradiation durations.
    Methods: A retrospective comparative study of patients with percent tissue altered ≥35%, undergoing simultaneous CXL during sub-Bowman's keratomileusis were recruited. Following riboflavin application, they underwent ultraviolet-A (UVA) irradiation (18 mW/cm
    Results: The baseline characteristics were similar between the 40 eyes/patients treated using the 2-min protocol and the 33 eyes/patients treated with the 3-min protocol (
    Conclusions: A comparable volume of crosslinked corneal tissue can be achieved by using a shorter UVA irradiation duration. Additional duration of UVA irradiation could lead to delay in visual rehabilitation after simultaneous sub-Bowman's keratomileusis and CXL.
    MeSH term(s) Collagen/metabolism ; Humans ; Keratomileusis, Laser In Situ/methods ; Lasers, Excimer/therapeutic use ; Myopia/surgery ; Photosensitizing Agents/therapeutic use ; Refraction, Ocular ; Retrospective Studies ; Ultraviolet Rays
    Chemical Substances Photosensitizing Agents ; Collagen (9007-34-5)
    Language English
    Publishing date 2022-04-27
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 632820-9
    ISSN 1744-5205 ; 0882-0538
    ISSN (online) 1744-5205
    ISSN 0882-0538
    DOI 10.1080/08820538.2022.2070026
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    Zs.A 2153: Show issues Location:
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  9. Article ; Online: Outcomes and prognostic factors of cataract surgery in cytomegalovirus-related anterior uveitis.

    Wan, Kelvin H / Liu, Ke / Lam, Nai Man / Chow, Vanissa W S

    Journal of cataract and refractive surgery

    2022  Volume 48, Issue 9, Page(s) 1031–1036

    Abstract: Purpose: To evaluate the outcomes of cataract surgery in patients with cytomegalovirus (CMV) anterior uveitis and factors associated with final visual outcome.: Setting: Hong Kong Eye Hospital, Hong Kong.: Design: Retrospective case series.: ... ...

    Abstract Purpose: To evaluate the outcomes of cataract surgery in patients with cytomegalovirus (CMV) anterior uveitis and factors associated with final visual outcome.
    Setting: Hong Kong Eye Hospital, Hong Kong.
    Design: Retrospective case series.
    Methods: History, clinical characteristics, corrected distance visual acuity (CDVA), medications, and complications of CMV anterior uveitic eyes that underwent cataract surgery between 2010 and 2020 were reviewed.
    Results: This study included 26 eyes of 26 patients undergoing phacoemulsification. The median duration of disease was 4.8 years, and the median quiescent period preoperatively was 2.3 years. None required pupil manipulation or had significant intraoperative complications. The median CDVA improved from 20/100 (interquartile range [IQR] 20/200 to 20/50) preoperatively to 20/30 (IQR 20/40 to 20/25) at 1 year and 20/35 (IQR 20/50 to 20/30) at the last follow-up at a median of 4.9 years postoperatively ( P < .001). CDVA improved in 19 eyes (73.1%) and was ≥20/40 in 18 eyes (69.2%). In the multivariate regression model, preoperative use of topical 0.15% ganciclovir (β = 0.33, 95% CI 0.17 to 0.48, P < .001) and adjunctive intraoperative intracameral dexamethasone 0.4 mg (β = 0.19, 95% CI 0.01 to 0.36, P = .043) were associated with a better final CDVA. Loss of CDVA and poor postoperative CDVA visual acuity were mostly attributed to uveitic glaucoma, but preoperative glaucoma or the number of antiglaucoma medications did not affect final CDVA.
    Conclusions: Cataract surgery in eyes with CMV anterior uveitis was safe and CDVA significantly improved and remained sustained postoperatively. Topical ganciclovir 0.15% preoperatively and intracameral corticosteroid intraoperatively seem to maximize the final visual outcome.
    MeSH term(s) Cataract ; Cytomegalovirus ; Cytomegalovirus Infections ; Follow-Up Studies ; Ganciclovir ; Glaucoma ; Humans ; Lens Implantation, Intraocular ; Phacoemulsification ; Postoperative Complications ; Prognosis ; Retrospective Studies ; Uveitis ; Uveitis, Anterior ; Vision Disorders
    Chemical Substances Ganciclovir (P9G3CKZ4P5)
    Language English
    Publishing date 2022-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/j.jcrs.0000000000000929
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  10. Article ; Online: Wavefront aberrometry repeatability and agreement-A comparison between Pentacam AXL Wave, iTrace and OPD-Scan III.

    Wan, Kelvin H / Liao, Xu Lin / Yu, Marco / Tsui, Rachel W Y / Chow, Vanissa W S / Chong, Kelvin K L / Chan, Tommy C Y

    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)

    2022  Volume 42, Issue 6, Page(s) 1326–1337

    Abstract: Introduction: To compare intrasession agreement and repeatability of wavefront aberration measurements from three different aberrometers obtained using Hartmann-Shack, ray tracing and automated retinoscopy methods, as well as their interdevice agreement. ...

    Abstract Introduction: To compare intrasession agreement and repeatability of wavefront aberration measurements from three different aberrometers obtained using Hartmann-Shack, ray tracing and automated retinoscopy methods, as well as their interdevice agreement.
    Methods: Three consecutive measurements were obtained using the Pentacam AXL Wave, the iTrace and the OPD-Scan III in 47 eyes of 47 patients. Wavefront refractions, root mean square of total aberrations (RMS total), RMS of higher-order aberrations (HOA) and second-, third- and fourth-order HOAs were exported for 4-mm pupils. Wavefront refractions were converted into vector components: M, J
    Results: The intrasession agreement and repeatability of RMS HOA were comparable between the three devices; both the Pentacam AXL Wave and the OPD-Scan III had better intrasession agreement and repeatability for the RMS total than the iTrace (p ≤ 0.02). Intrasession repeatability for the majority of second- and third-order aberrations was better on the Pentacam AXL Wave than on the iTrace (p ≤ 0.01) and OPD-Scan III (p ≤ 0.04), although their agreement and repeatability in spherical aberration were comparable (p ≥ 0.24). Significant systematic differences and proportional bias were detected for almost all refraction power vectors and Zernike coefficients among the three devices.
    Conclusions: In this study, all three devices provided good-to-excellent agreement for aberration measurements. Most of the individual Zernike's components were not exchangeable between different aberrometers. Their relative intrasession performance in agreement and repeatability varied significantly across different ocular aberration parameters.
    MeSH term(s) Humans ; Aberrometry/methods ; Corneal Wavefront Aberration ; Refraction, Ocular ; Reproducibility of Results ; Retinoscopy
    Language English
    Publishing date 2022-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 604564-9
    ISSN 1475-1313 ; 0275-5408
    ISSN (online) 1475-1313
    ISSN 0275-5408
    DOI 10.1111/opo.13047
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