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  1. Article ; Online: Bilateral helicoid peri-papillary sub-retinal fibrosis due to a biallelic

    Hassanpoor, Narges / Ebrahimiadib, Nazanin / Riazi-Esfahani, Hamid / Moghaddasi, Afrooz / Suri, Fatemeh

    European journal of ophthalmology

    2024  , Page(s) 11206721241234396

    Abstract: Background: To describe different clinical presentations of a same : Design: Interventional family study.: Results: Our first case was a one-year-old male child with high hyperopia and refractive accommodative esotropia. In retinal examination, ... ...

    Abstract Background: To describe different clinical presentations of a same
    Design: Interventional family study.
    Results: Our first case was a one-year-old male child with high hyperopia and refractive accommodative esotropia. In retinal examination, peri-papillary sub-retinal fibrosis with a helicoid configuration was observed in both eyes. The parents and the only sibling had no pathologic findings in the eyes. The child showed to have severely reduced responses in both photopic and scotopic electroretinogram components. In the genetic investigation, a homozygous autosomal recessive mutation in the
    Conclusion: Same
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721241234396
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    Zs.A 3342: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  2. Article ; Online: Atypical Keratic Precipitates in Fuchs Uveitis.

    Zarei, Mohammad / Ebrahimiadib, Nazanin

    Ocular immunology and inflammation

    2020  Volume 29, Issue 7-8, Page(s) 1363–1365

    Abstract: ... ...

    Abstract Purpose
    MeSH term(s) Adult ; Corneal Diseases/diagnosis ; Endothelium, Corneal/pathology ; Humans ; Male ; Uveitis, Anterior/diagnosis ; Visual Acuity
    Language English
    Publishing date 2020-05-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2020.1754433
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    Zs.A 4004: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article: Renal Function following Fluorescein Angiography in Diabetic Patients with Chronic Kidney Disease.

    Ebrahimiadib, Nazanin / Hadavand Mirzaei, Shaghayegh / Riazi-Esfahani, Hamid / Amini, Manouchehr

    Journal of ophthalmic & vision research

    2023  Volume 18, Issue 2, Page(s) 170–174

    Abstract: Purpose: To evaluate the effect of fluorescein dye usage on renal function in patients with diabetic retinopathy (DR) and chronic kidney disease (CKD).: Methods: Diabetic patients with retinopathy who were candidate for fundus fluorescein angiography ...

    Abstract Purpose: To evaluate the effect of fluorescein dye usage on renal function in patients with diabetic retinopathy (DR) and chronic kidney disease (CKD).
    Methods: Diabetic patients with retinopathy who were candidate for fundus fluorescein angiography (FA) were evaluated for serum creatinine and urea levels within five days prior to performing the FA. Serum creatinine levels of 1.5 mg/dl or more in males and 1.4 mg/dl or more in females were both identified as CKD and were included in the study. An increase of 0.5 mg/dl or 25% in creatinine after FA was considered as contrast-induced acute kidney injury (AKI). Estimated glomerular filtration rate (eGFR) was also calculated for all patients using a CKD-Epi formula. CKD grading was determined based on eGFR values.
    Results: Forty-two patients agreed to participate, of which 23 (54.8%) were male. Seventeen patients were identified with grade 3a or lower CKD, 12 with grade 3b, 11 with grade 4, and two with grade 5 CKD. Considering all grades of CKD, the mean blood urea before and after angiography was 58.48
    Conclusion: According to the findings of this study, FA does not seem to further deteriorate kidney function in patients with diabetic associated CKD.
    Language English
    Publishing date 2023-04-19
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 2008-2010
    ISSN 2008-2010
    DOI 10.18502/jovr.v18i2.13183
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  4. Article ; Online: Correspondence.

    Riazi-Esfahani, Hamid / Ebrahimiadib, Nazanin / Kalili Pour, Elias / Mahmoudi, Alireza

    Retina (Philadelphia, Pa.)

    2021  Volume 41, Issue 3, Page(s) e37–e38

    Language English
    Publishing date 2021-01-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003120
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    Zs.A 1724: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article: Langerhans Cell Histiocytosis of the Uvea with a Ciliochoroidal Mass: A Case Report of Management with Systemic Therapy.

    Ghassemi, Fariba / Riazi-Esfahani, Hamid / Ebrahimiadib, Nazanin / Amini, Abdulrahim / Mahdizad, Zahra

    Case reports in ophthalmological medicine

    2023  Volume 2023, Page(s) 5543131

    Abstract: Background: This study is aimed at exploring a case of choroidal Langerhans cell histiocytosis (LCH) successfully treated with systemic corticosteroid and immunosuppressant. : Conclusions: Intraocular involvement of LCH is rare and can present with ... ...

    Abstract Background: This study is aimed at exploring a case of choroidal Langerhans cell histiocytosis (LCH) successfully treated with systemic corticosteroid and immunosuppressant.
    Conclusions: Intraocular involvement of LCH is rare and can present with or without a history of multisystemic disease. The diagnosis is challenging, and the standard treatment is not established. Systemic anti-inflammatory and immunosuppressive therapy could be an effective treatment, as the LCH itself contains an essential element of inflammation and the symptoms may be mainly inflammatory.
    Language English
    Publishing date 2023-09-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2659091-8
    ISSN 2090-6730 ; 2090-6722
    ISSN (online) 2090-6730
    ISSN 2090-6722
    DOI 10.1155/2023/5543131
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  6. Article ; Online: Henle fiber layer hemorrhage associated with combined central retinal vein occlusion and cilioretinal artery occlusion: a case report.

    Riazi-Esfahani, Hamid / Ebrahimiadib, Nazanin / Hamzeh, Nikoo / Fadakar, Kaveh / Khalili Pour, Elias

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 355

    Abstract: Background: The purpose of this study is to describe a patient who experienced simultaneous central retinal vein and cilioretinal artery occlusions, as well as perifoveal hemorrhage in the Henle fiber.: Case presentation: A 67-year-old Iranian woman ... ...

    Abstract Background: The purpose of this study is to describe a patient who experienced simultaneous central retinal vein and cilioretinal artery occlusions, as well as perifoveal hemorrhage in the Henle fiber.
    Case presentation: A 67-year-old Iranian woman presented with a 3-day history of reduced vision in her left eye. Venous tortuosity and retinal hemorrhage were observed in the retina, together with whitened regions around the fovea, consistent with the diagnosis of central retinal vein occlusion in conjunction with cilioretinal artery occlusion. In structural and en face optical coherence tomography, star-shaped hemorrhages were observed around the fovea, which looked hyperreflective in the Henle fiber layer.
    Conclusions: We present a case of central retinal vein occlusion exacerbated by cilioretinal occlusion and hemorrhage in the Henle fiber layer. The hemorrhage is most likely the result of increased intraluminal pressure in the deep capillary plexus.
    MeSH term(s) Female ; Humans ; Aged ; Retinal Vein Occlusion/complications ; Retinal Vein Occlusion/diagnosis ; Iran ; Retina ; Hemorrhage/diagnostic imaging ; Hemorrhage/etiology ; Cerebrovascular Disorders ; Arteries
    Language English
    Publishing date 2023-08-20
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04100-y
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  7. Article ; Online: Hemicentral retinal vein occlusion in a patient with a history of coronavirus disease 2019 infection: a case report and review of the literature.

    Riazi-Esfahani, Hamid / Sadeghi, Reza / Soleymanzadeh, Mahdi / Farrokhpour, Hossein / Bazvand, Fatemeh / Ebrahimiadib, Nazanin / Khalili Pour, Elias / Mirghorbani, Masoud

    Journal of medical case reports

    2024  Volume 18, Issue 1, Page(s) 50

    Abstract: Background: Considering the various manifestations of coronavirus disease 2019 and its imperative importance in terms of the right clinical approach and early management, we sought to present a hemicentral retinal vein occlusion case, with a history of ... ...

    Abstract Background: Considering the various manifestations of coronavirus disease 2019 and its imperative importance in terms of the right clinical approach and early management, we sought to present a hemicentral retinal vein occlusion case, with a history of heterozygosity of methylenetetrahydrofolate reductase (MTHFR) genes and potential for clotting complications as a late manifestation of coronavirus disease 2019, and provide a brief review of reported retinal vein occlusion cases in patients with coronavirus disease 2019.
    Case presentation: A 35-year-old Iranian patient presented with a visual impairment in the left eye 4 months after recovering from coronavirus disease 2019. He reported a mild blurring of vision in the same eye a few days after admission due to coronavirus disease 2019. The ophthalmic evaluation was compatible with hemicentral retinal vein occlusion. Systemic and laboratory workups were negative except for borderline protein C activity, homocysteine levels, and heterozygosity of MTHFR genes. The patient was scheduled to receive three monthly intravitreal antivascular endothelial growth factor injections.
    Conclusion: We present a case of inferior hemicentral retinal vein occlusion case with an MTHFR mutation with sequential loss of vision 4 months after coronavirus disease 2019 to make clinicians aware of the possibility of late ocular coronavirus disease 2019 manifestations.
    MeSH term(s) Male ; Humans ; Adult ; Retinal Vein Occlusion/etiology ; Retinal Vein Occlusion/complications ; Iran ; COVID-19/complications ; Mutation ; Eye
    Language English
    Publishing date 2024-02-11
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04333-x
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  8. Article ; Online: Assessment of retinal and choroidal vessel density and nerve fibre layer thickness changes after orbitotomy in patients with severe non-active thyroid orbitopathy: a prospective study.

    Jamshidian Tehrani, Mansoreh / Niktinat, Hanieh / Ebrahimiadib, Nazanin / Jafari, Behzad / Rafizadeh, Seyed Mohsen / Kasaee, Abolfazl

    International ophthalmology

    2023  Volume 43, Issue 12, Page(s) 4427–4433

    Abstract: Purpose: To evaluate the optical coherence tomography angiogram changes in non-active severe thyroid-related ophthalmopathy patients after cosmetic bone decompression.: Methods: Eighteen patients (25 eyes) with severe not active not compressive (NANC) ...

    Abstract Purpose: To evaluate the optical coherence tomography angiogram changes in non-active severe thyroid-related ophthalmopathy patients after cosmetic bone decompression.
    Methods: Eighteen patients (25 eyes) with severe not active not compressive (NANC) TED who were candidates for decompression surgery for cosmetic reasons were included in this study, and a 3 × 3 mm macular scan was used to measure vessel density and RNFL thickness. Whole macular vessel density in its superficial, deep and choriocapillaris layers was evaluated. The following data were extracted for each of layers: superior and inferior hemispheres, fovea, parafoveal vessel density, its superior and inferior hemispheres, and temporal, superior, nasal and inferior quadrant.
    Results: The mean RPC increased postoperatively, which was statistically significant in small vessels of peripapillary area (p-value = 0.045). The mean RNFL thickness decreased after surgery and it was statistically significant in the peripapillary (p-value = 0.032) and Inferior-Hemifield area (p-value = 0.036). The choriocapillaris changes were significant in Superior-Hemifield (p-value = 0.031) and Fovea (p-value = 0.03).
    Conclusion: Thyroid-associated orbitopathy patients have a tendency to decrease vascular density and correlated with disease activity more than stage of orbitopathy. There was not a strong and even discrepant result in linkage of RNFL thickness and other optic nerve function tests and TED patient status and it is needed to do studies with more epidemiologic power and same methodology of study to be more comparable.
    MeSH term(s) Humans ; Graves Ophthalmopathy/diagnosis ; Graves Ophthalmopathy/surgery ; Optic Disk/blood supply ; Prospective Studies ; Retinal Vessels ; Tomography, Optical Coherence/methods ; Nerve Fibers
    Language English
    Publishing date 2023-10-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-023-02790-3
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    Zs.A 1479: Show issues Location:
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  9. Article ; Online: Automated diagnosis of plus disease in retinopathy of prematurity using quantification of vessels characteristics.

    Sharafi, Sayed Mehran / Ebrahimiadib, Nazanin / Roohipourmoallai, Ramak / Farahani, Afsar Dastjani / Fooladi, Marjan Imani / Khalili Pour, Elias

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6375

    Abstract: The condition known as Plus disease is distinguished by atypical alterations in the retinal vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of Plus disease is subjective and qualitative in nature. The utilization of ... ...

    Abstract The condition known as Plus disease is distinguished by atypical alterations in the retinal vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of Plus disease is subjective and qualitative in nature. The utilization of quantitative methods and computer-based image analysis to enhance the objectivity of Plus disease diagnosis has been extensively established in the literature. This study presents the development of a computer-based image analysis method aimed at automatically distinguishing Plus images from non-Plus images. The proposed methodology conducts a quantitative analysis of the vascular characteristics linked to Plus disease, thereby aiding physicians in making informed judgments. A collection of 76 posterior retinal images from a diverse group of infants who underwent screening for Retinopathy of Prematurity (ROP) was obtained. A reference standard diagnosis was established as the majority of the labeling performed by three experts in ROP during two separate sessions. The process of segmenting retinal vessels was carried out using a semi-automatic methodology. Computer algorithms were developed to compute the tortuosity, dilation, and density of vessels in various retinal regions as potential discriminative characteristics. A classifier was provided with a set of selected features in order to distinguish between Plus images and non-Plus images. This study included 76 infants (49 [64.5%] boys) with mean birth weight of 1305 ± 427 g and mean gestational age of 29.3 ± 3 weeks. The average level of agreement among experts for the diagnosis of plus disease was found to be 79% with a standard deviation of 5.3%. In terms of intra-expert agreement, the average was 85% with a standard deviation of 3%. Furthermore, the average tortuosity of the five most tortuous vessels was significantly higher in Plus images compared to non-Plus images (p ≤ 0.0001). The curvature values based on points were found to be significantly higher in Plus images compared to non-Plus images (p ≤ 0.0001). The maximum diameter of vessels within a region extending 5-disc diameters away from the border of the optic disc (referred to as 5DD) exhibited a statistically significant increase in Plus images compared to non-Plus images (p ≤ 0.0001). The density of vessels in Plus images was found to be significantly higher compared to non-Plus images (p ≤ 0.0001). The classifier's accuracy in distinguishing between Plus and non-Plus images, as determined through tenfold cross-validation, was found to be 0.86 ± 0.01. This accuracy was observed to be higher than the diagnostic accuracy of one out of three experts when compared to the reference standard. The implemented algorithm in the current study demonstrated a commendable level of accuracy in detecting Plus disease in cases of retinopathy of prematurity, exhibiting comparable performance to that of expert diagnoses. By engaging in an objective analysis of the characteristics of vessels, there exists the possibility of conducting a quantitative assessment of the disease progression's features. The utilization of this automated system has the potential to enhance physicians' ability to diagnose Plus disease, thereby offering valuable contributions to the management of ROP through the integration of traditional ophthalmoscopy and image-based telemedicine methodologies.
    MeSH term(s) Infant, Newborn ; Infant ; Male ; Humans ; Female ; Retinopathy of Prematurity/diagnosis ; Infant, Premature ; Retinal Vessels/diagnostic imaging ; Retina ; Gestational Age ; Reproducibility of Results
    Language English
    Publishing date 2024-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57072-4
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  10. Article ; Online: Correspondence.

    Hassanpoor, Narges / Ebrahimiadib, Nazanin / Riazi Esfahani, Hamid / Niyousha, Mohammad Reza

    Retinal cases & brief reports

    2020  Volume 16, Issue 1, Page(s) 3

    Language English
    Publishing date 2020-05-07
    Publishing country United States
    Document type Letter ; Comment
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001004
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