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  1. Article ; Online: A benzodiazepine activator locks K

    Schreiber, Julian A / Möller, Melina / Zaydman, Mark / Zhao, Lu / Beller, Zachary / Becker, Sebastian / Ritter, Nadine / Hou, Panpan / Shi, Jingyi / Silva, Jon / Wrobel, Eva / Strutz-Seebohm, Nathalie / Decher, Niels / Schmitt, Nicole / Meuth, Sven G / Düfer, Martina / Wünsch, Bernhard / Cui, Jianmin / Seebohm, Guiscard

    Communications biology

    2022  Volume 5, Issue 1, Page(s) 301

    Abstract: Loss-of-function mutations in ... ...

    Abstract Loss-of-function mutations in K
    MeSH term(s) Benzodiazepines/pharmacology ; Ion Channel Gating ; Mutation
    Chemical Substances Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2022-04-01
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-022-03229-8
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  2. Book ; Thesis: 2-Methylacetoacetyl-Coenzym-A-Thiolase(MAT)-Mangel (Beta-Ketothiolase-Mangel)

    Schmitt, Robert Niklas

    Manifestation und klinischer Verlauf

    2017  

    Title variant Zwei-Methylacetoacetyl-Coenzym-A-Thiolase(MAT)-Mangel (Beta-Ketothiolase-Mangel)
    Author's details vorgelegt von Robert Niklas Schmitt
    Language German
    Size 86 Seiten, Diagramme, 30 cm
    Publishing place Freiburg im Breisgau
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg im Breisgau, 2017
    HBZ-ID HT019519919
    Database Catalogue ZB MED Medicine, Health

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    2017 E 1871 order for loan Magazin

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  3. Article ; Online: Fungal Host Affects Photosynthesis in a Lichen Holobiont.

    Schulz, Meike / Schmitt, Imke / Weber, Daniel / Dal Grande, Francesco

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 12

    Abstract: Corals and lichens are iconic examples of photosynthetic holobionts, i.e., ecological and evolutionary units resulting from the tightly integrated association of algae and prokaryotic microbiota with animal or fungal hosts, respectively. While the role ... ...

    Abstract Corals and lichens are iconic examples of photosynthetic holobionts, i.e., ecological and evolutionary units resulting from the tightly integrated association of algae and prokaryotic microbiota with animal or fungal hosts, respectively. While the role of the coral host in modulating photosynthesis has been clarified to a large extent in coral holobionts, the role of the fungal host in this regard is far less understood. Here, we address this question by taking advantage of the recent discovery of highly specific fungal-algal pairings corresponding to climatically adapted ecotypes of the lichen-forming genus
    Language English
    Publishing date 2022-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8121267
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  4. Article ; Online: A Photopolymerizable Biocompatible Hyaluronic Acid Hydrogel Promotes Early Articular Cartilage Repair in a Minipig Model In Vivo.

    Gao, Liang / Beninatto, Riccardo / Oláh, Tamás / Goebel, Lars / Tao, Ke / Roels, Rebecca / Schrenker, Steffen / Glomm, Julianne / Venkatesan, Jagadeesh K / Schmitt, Gertrud / Sahin, Ebrar / Dahhan, Ola / Pavan, Mauro / Barbera, Carlo / Lucia, Alba Di / Menger, Michael D / Laschke, Matthias W / Cucchiarini, Magali / Galesso, Devis /
    Madry, Henning

    Advanced healthcare materials

    2023  Volume 12, Issue 26, Page(s) e2300931

    Abstract: Articular cartilage defects represent an unsolved clinical challenge. Photopolymerizable hydrogels are attractive candidates supporting repair. This study investigates the short-term safety and efficacy of two novel hyaluronic acid (HA)-triethylene ... ...

    Abstract Articular cartilage defects represent an unsolved clinical challenge. Photopolymerizable hydrogels are attractive candidates supporting repair. This study investigates the short-term safety and efficacy of two novel hyaluronic acid (HA)-triethylene glycol (TEG)-coumarin hydrogels photocrosslinked in situ in a clinically relevant large animal model. It is hypothesized that HA-hydrogel-augmented microfracture (MFX) is superior to MFX in enhancing early cartilage repair, and that the molar degree of substitution and concentration of HA affects repair. Chondral full-thickness defects in the knees of adult minipigs are treated with either 1) debridement (No MFX), 2) debridement and MFX, 3) debridement, MFX, and HA hydrogel (30% molar derivatization, 30 mg mL
    MeSH term(s) Animals ; Swine ; Cartilage, Articular/pathology ; Swine, Miniature ; Hyaluronic Acid/pharmacology ; Hydrogels/pharmacology ; Models, Animal
    Chemical Substances Hyaluronic Acid (9004-61-9) ; Hydrogels
    Language English
    Publishing date 2023-08-18
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649576-4
    ISSN 2192-2659 ; 2192-2640
    ISSN (online) 2192-2659
    ISSN 2192-2640
    DOI 10.1002/adhm.202300931
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  5. Book ; Thesis: Prospektiv randomisierte Doppelblind-Studie zur postoperativen Wundbehandlung nach kolorektalen Eingriffen mit wassergefilterter Infrarot-A-Strahlung versus Kompressenverband

    Schmitt, Martin

    2013  

    Author's details vorgelegt von Martin Schmitt
    Language German
    Size 87 Bl. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2014
    HBZ-ID HT018640482
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 E 740 order for loan Magazin

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  6. Article ; Online: Soft Robots Manufacturing: A Review.

    Schmitt, François / Piccin, Olivier / Barbé, Laurent / Bayle, Bernard

    Frontiers in robotics and AI

    2018  Volume 5, Page(s) 84

    Abstract: The growing interest in soft robots comes from the new possibilities offered by these systems to cope with problems that cannot be addressed by robots built from rigid bodies. Many innovative solutions have been developed in recent years to design soft ... ...

    Abstract The growing interest in soft robots comes from the new possibilities offered by these systems to cope with problems that cannot be addressed by robots built from rigid bodies. Many innovative solutions have been developed in recent years to design soft components and systems. They all demonstrate how soft robotics development is closely dependent on advanced manufacturing processes. This review aims at giving an insight on the current state of the art in soft robotics manufacturing. It first puts in light the elementary components that can be used to develop soft actuators, whether they use fluids, shape memory alloys, electro-active polymers or stimuli-responsive materials. Other types of elementary components, such as soft smart structures or soft-rigid hybrid systems, are then presented. The second part of this review deals with the manufacturing methods used to build complete soft structures. It includes molding, with possibly reinforcements and inclusions, additive manufacturing, thin-film manufacturing, shape deposition manufacturing, and bonding. The paper conclusions sums up the pros and cons of the presented techniques, and open to developing topics such as design methods for soft robotics and sensing technologies.
    Language English
    Publishing date 2018-07-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781824-X
    ISSN 2296-9144 ; 2296-9144
    ISSN (online) 2296-9144
    ISSN 2296-9144
    DOI 10.3389/frobt.2018.00084
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  7. Article: CHARACTERIZATION OF A FOLLICULAR CELL CARCINOMA OF THE THYROID IN A YELLOWBAR ANGELFISH (POMACANTHUS MACULOSUS).

    Simeone, Claire A / St Leger, Judy / Schmitt, Todd L / Nollens, Hendrik H

    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

    2015  Volume 46, Issue 2, Page(s) 431–434

    Abstract: Histopathologic diagnosis of thyroid neoplasia in teleosts is complicated, because thyroid tissue is unencapsulated, and normal tissue can have wide ectopic extensions. Assessment of thyroid hormone concentrations in conjunction with histologic ... ...

    Abstract Histopathologic diagnosis of thyroid neoplasia in teleosts is complicated, because thyroid tissue is unencapsulated, and normal tissue can have wide ectopic extensions. Assessment of thyroid hormone concentrations in conjunction with histologic evaluation of thyroid carcinoma has not been reported in teleosts, even though routinely performed in other species. A yellowbar angelfish (Pomacanthus maculosus) presented with a mass that extended beyond the gill arches. Partial surgical resection was performed, and a histologic diagnosis of thyroid carcinoma was made. Plasma from the affected fish and two control Pomacanthus were used to assess thyroid hormone concentrations using a domestic mammalian assay. Thyroid-stimulating hormone and throxine were undetectable in two of three fish. Triiodothyronine was lower in the affected fish than in controls. The tumor did not appear to be actively secreting hormone. This is the first characterization of thyroid tumors and corresponding thyroid hormones in teleosts, which may assist in diagnosis of this disease.
    MeSH term(s) Animals ; Carcinoma/diagnosis ; Carcinoma/pathology ; Carcinoma/veterinary ; Fish Diseases/diagnosis ; Fish Diseases/pathology ; Fishes ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/veterinary ; Thyrotropin/blood ; Thyrotropin/metabolism ; Triiodothyronine/blood ; Triiodothyronine/metabolism
    Chemical Substances Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5)
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2174930-9
    ISSN 1937-2825 ; 1042-7260
    ISSN (online) 1937-2825
    ISSN 1042-7260
    DOI 10.1638/2014-0223R1.1
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  8. Article: La psychiatrie a-t-elle encore un intérêt dans l’approche de l’âme de ses patients ?

    Salles, J / Sporer, M / Schmitt, L

    L'Encephale

    2019  Volume 45, Issue 3, Page(s) 193–194

    Title translation Is still psychiatry interested by patient's souls?
    MeSH term(s) Child ; Ethics, Medical ; Humans ; Mental Disorders/psychology ; Mental Disorders/therapy ; Mind-Body Relations, Metaphysical/ethics ; Mind-Body Relations, Metaphysical/physiology ; Neurosciences/ethics ; Neurosciences/methods ; Neurosciences/trends ; Psychiatry/ethics ; Psychiatry/methods ; Psychiatry/trends ; Psychopathology/ethics ; Psychopathology/methods ; Psychopathology/trends ; Religion and Medicine ; Religion and Psychology ; Therapies, Investigational/ethics ; Therapies, Investigational/methods ; Therapies, Investigational/trends
    Language French
    Publishing date 2019-05-18
    Publishing country France
    Document type Editorial
    ZDB-ID 214431-1
    ISSN 0013-7006
    ISSN 0013-7006
    DOI 10.1016/j.encep.2019.03.002
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    Ui II Zs.65: Show issues Location:
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  9. Article ; Online: Nicolás de Cusa en los márgenes a Confessiones

    Alexia Schmitt

    Patristica et Mediaevalia, Vol 37, Pp 3-

    codex cusanus 34

    2016  Volume 14

    Abstract: ... de Agustín, podemos inferir algunas de las razones por las que el Cusano considera a Agustín ... como un platónico: debido a su exégesis del Prólogo del Evangelio de Juan, su asimilación de los “libros platónicos ... y el camino hacia la verdad que Agustín proponía: desde lo exterior a la mente humana, a su interior ...

    Abstract De las notas marginales de Nicolás de Cusa al Codex Cusanus 34, que contiene las Confesiones de Agustín, podemos inferir algunas de las razones por las que el Cusano considera a Agustín como un platónico: debido a su exégesis del Prólogo del Evangelio de Juan, su asimilación de los “libros platónicos” y el camino hacia la verdad que Agustín proponía: desde lo exterior a la mente humana, a su interior y por encima de ella. Nicolás también encuentra una anticipación de estos dos puntos de su doctrina de la visión de Dios en la bondad de las criaturas, Dios viendo es Dios creando. Nicolás lleva hasta sus últimas consecuencias esta doctrina agustiniana con la fórmula “Sis tu tuus, et Ego ero tuus”: Dios está presente en el interior del hombre, porque todo hombre encuentra su perfección en Jesús.
    Keywords nicolás de cusa ; agustín ; visio dei ; mente humana ; bondad ; History of scholarship and learning. The humanities ; AZ20-999 ; Philosophy (General) ; B1-5802
    Language German
    Publishing date 2016-12-01T00:00:00Z
    Publisher Universidad de Buenos Aires
    Document type Article ; Online
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  10. Article ; Online: Experiência de 555 tireoidectomias consecutivas no Hospital de Clínicas de Porto Alegre (1987 a 2000)

    Alceu Migliavacca / José Ricardo Guimarães / Claudio Nhuch / Caio da S. Schmitt / Gabriele C. Miotto

    Clinical and Biomedical Research, Vol 21, Iss

    2022  Volume 1

    Abstract: OBJETIVO: O objetivo deste estudo foi de descrever o perfil de pacientes submetidos à cirurgia de tireóide. MATERIAIS E MÉTODOS: Descrevemos o perfil de 555 pacientes submetidos a 593 cirurgias de tireóide no Hospital de Clínicas de Porto Alegre, entre ... ...

    Abstract OBJETIVO: O objetivo deste estudo foi de descrever o perfil de pacientes submetidos à cirurgia de tireóide. MATERIAIS E MÉTODOS: Descrevemos o perfil de 555 pacientes submetidos a 593 cirurgias de tireóide no Hospital de Clínicas de Porto Alegre, entre 1987 e 2000, no que diz respeito à indicação cirúrgica, tipo de patologia, cirurgia realizada e incidência de complicações. Definimos também a sensibilidade, especificidade e valores preditivos da punção biópsia aspirativa e anatomopatológico de congelação. Dos pacientes operados, 504 (85%) eram do sexo feminino. A idade média foi de 48,1 anos. A indicação cirúrgica mais freqüente foi suspeita de malignidade (58,3%), sendo o procedimento mais comumente realizado a lobectomia (53,3%). RESULTADOS: O achado anatomopatológico mais comum foi o bócio colóide em 70%. Neoplasias foram encontradas em 99 procedimentos (16,1%). As complicações mais incidentes foram hipoparatireoidismo transitório (8,6%), hipoparatireoidismo permanente (4,7%) e lesão transitória unilateral do nervo laríngeo inferior (4,9%). CONCLUSÃO: A cirurgia de tireóide é um procedimento seguro e que apresenta taxas aceitáveis de complicações.
    Keywords Tireóide ; bócio ; neoplasia de tireóide ; punção biópsia aspirativa ; tireoidectomia ; Medicine ; R
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Hospital de Clinicas de Porto Alegre
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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