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  1. Article ; Online: Venogenic erectile dysfunction: diagnosis on computed tomography cavernosography and endovascular treatment using an anterograde access via deep dorsal penile vein.

    Hoppe, Hanno / Diehm, Nicolas

    CVIR endovascular

    2022  Volume 5, Issue 1, Page(s) 10

    Abstract: Background: The underlying etiologies of erectile dysfunction may be manifold. Among them, vasculogenic etiologies are of increasing relevance and are not strictly limited to the elderly population. According to recent study, venogenic erectile ... ...

    Abstract Background: The underlying etiologies of erectile dysfunction may be manifold. Among them, vasculogenic etiologies are of increasing relevance and are not strictly limited to the elderly population. According to recent study, venogenic erectile dysfunction appears to be even more relevant than arteriogenic erectile dysfunction. Venogenic erectile dysfunction due to venous leakage causes insufficient penile blood retention. Proper diagnosis of venous leakage should include both color Doppler flow analysis and computed tomography cavernosography for adequate patient selection and treatment planning. Besides surgical ligation of penile draining veins, endovascular treatment methods may demonstrate more promising results. Especially endovascular embolization of venous leakage using an anterograde access via deep dorsal penile veins appears to be more beneficial for patients' clinical outcome and awareness of this technique should be raised among endovascular interventionalists.
    Case presentation: A 47-year-old man was diagnosed with venogenic erectile dysfunction due to venous leakage on color Doppler flow analysis and computed tomography cavernosography. He did not respond to PDE-5-inhibitors. This patient demonstrated major venous leakage of paired deep dorsal penile veins via periprostatic veins and internal pudendal veins draining into both iliohypogastric veins. This patient's venous leak was treated with endovascular embolization using an anterograde access via deep dorsal penile veins.
    Conclusion: This patient's erectile dysfunction due to venous leakage, based on findings in color Doppler flow analysis and computed tomography cavernosography, was embolized using an anterograde access via deep dorsal penile veins as a minimally-invasive endovascular treatment option.
    Language English
    Publishing date 2022-02-03
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2520-8934
    ISSN (online) 2520-8934
    DOI 10.1186/s42155-022-00283-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: To the editor-an update on endovascular treatment of venogenic erectile dysfunction.

    Hoppe, Hanno / Diehm, Nicolas

    CVIR endovascular

    2022  Volume 5, Issue 1, Page(s) 30

    Language English
    Publishing date 2022-06-29
    Publishing country Switzerland
    Document type Letter
    ISSN 2520-8934
    ISSN (online) 2520-8934
    DOI 10.1186/s42155-022-00310-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Videomikroskopisches Monitoring

    Hoppe, Hanno

    Entwicklung und Anwendung eines neuen bildgebenden Verfahrens zur Diagnose der frühen Abstossung nach Dünndarmtransplantationen

    1999  

    Author's details vorgelegt von Hanno Hoppe
    Language German
    Size 77 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Würzburg, Univ., Diss., 1999
    HBZ-ID HT012817536
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Percutaneous Treatment of Venous Erectile Dysfunction.

    Hoppe, Hanno / Diehm, Nicholas

    Frontiers in cardiovascular medicine

    2021  Volume 7, Page(s) 626943

    Abstract: Erectile dysfunction is a defined as recurring inability to achieve and maintain satisfactory erection for sexual intercourse associated with relevant life impairment. The underlying etiologies may be manifold and complex. Currently, vascular etiologies ... ...

    Abstract Erectile dysfunction is a defined as recurring inability to achieve and maintain satisfactory erection for sexual intercourse associated with relevant life impairment. The underlying etiologies may be manifold and complex. Currently, vascular etiologies are highly prevalent especially amongst elderly men. Of special interest, especially venogenic causes are of increasing relevance. Therapeutic options comprise risk factor modification, pharmacotherapy, surgical treatment, and endovascular treatment. Especially endovascular treatment options have recently increased in popularity including transcatheter embolization procedures for veno-occlusive dysfunction.
    Language English
    Publishing date 2021-02-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2020.626943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Men with erectile dysfunction (ED) should be screened for cardiovascular risk factors - Cost-benefit considerations in Swiss men.

    Kalka, Christoph / Keo, Hak-Hong / Ingwersen, Maja / Knoechel, Jonas / Hoppe, Hanno / Do, Dai-Do / Schumacher, Martin / Diehm, Nicolas

    VASA. Zeitschrift fur Gefasskrankheiten

    2023  Volume 53, Issue 1, Page(s) 68–76

    MeSH term(s) Male ; Humans ; Erectile Dysfunction/diagnosis ; Erectile Dysfunction/epidemiology ; Erectile Dysfunction/therapy ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Cost-Benefit Analysis ; Risk Factors ; Switzerland/epidemiology ; Heart Disease Risk Factors
    Language English
    Publishing date 2023-12-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120977-2
    ISSN 1664-2872 ; 0301-1526
    ISSN (online) 1664-2872
    ISSN 0301-1526
    DOI 10.1024/0301-1526/a001105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Role of Lp(a) in patients with erectile dysfunction undergoing angioplasty for symptomatic pelvic artery disease.

    Kalka, Christoph / Lippik, Lisa / Wenzel, Folker / Hoppe, Hanno / Keo, Hak-Hong / Heiss, Christian / Diehm, Nicolas

    VASA. Zeitschrift fur Gefasskrankheiten

    2023  Volume 52, Issue 4, Page(s) 230–238

    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Erectile Dysfunction/diagnosis ; Erectile Dysfunction/therapy ; Retrospective Studies ; Impotence, Vasculogenic/diagnosis ; Impotence, Vasculogenic/therapy ; Angioplasty/adverse effects ; Atherosclerosis ; Arteries
    Language English
    Publishing date 2023-05-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120977-2
    ISSN 1664-2872 ; 0301-1526
    ISSN (online) 1664-2872
    ISSN 0301-1526
    DOI 10.1024/0301-1526/a001072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Diagnostic accuracy of coronary artery stenosis and thrombosis assessment using unenhanced multiplanar 3D post-mortem cardiac magnetic resonance imaging.

    Lombardo, Paolo / Lange-Herr, Nicolas / Hoppe, Hanno / Schwendener, Nicole / Jackowski, Christian / Klaus, Jeremias / Zech, Wolf-Dieter

    Forensic science international

    2023  Volume 353, Page(s) 111878

    Abstract: Background: A 3D sequence was introduced to unenhanced post-mortem cardiac magnetic resonance imaging (PMCMR) to enable multiplanar coronary artery image analysis and to investigate its diagnostic accuracy for the diagnosis of coronary artery stenosis ... ...

    Abstract Background: A 3D sequence was introduced to unenhanced post-mortem cardiac magnetic resonance imaging (PMCMR) to enable multiplanar coronary artery image analysis and to investigate its diagnostic accuracy for the diagnosis of coronary artery stenosis and thrombosis.
    Materials and methods: N = 200 forensic cases with suspected coronary artery pathology underwent 3 Tesla PMCMR (sequence used: T2 weighted transversal 3D turbo spin echo) before autopsy. Main coronary artery stenosis and thrombosis were assessed in PMCMR by multiplanar image analysis by two observers. Coronary artery histology was determined as the gold standard and compared to PMCMR. Sensitivity, specificity, negative (NPV) and positive predictive values (PPV) with 95% confidence intervals were calculated.
    Results: For all coronary arteries combined, sensitivity was 75% (PPV 73%) for the diagnosis of stenosis and 72% (PPV 71%) for the diagnosis of thrombosis. Specificity was 92% (NPV 90%) for correct diagnosis of non-existing stenosis and 97% (NPV 97%) for non-existing thrombosis. Sensitivity for correct diagnosis of different degrees of stenosis ranged between 67% and 80% (PPVs 67-82%); specificity ranged between 96% and 99% (NPVs 96-99%).
    Conclusion: Multiplanar PMCMR coronary artery stenosis and thrombosis assessment based on an unenhanced T2 weighted 3D sequence provide moderate sensitivity and high specificity for the diagnosis of coronary artery stenosis and/or thrombosis. Hence, 3D T2w PMCMR cannot reliably detect existing coronary artery stenosis and thrombosis but may be particularly useful for the exclusion of stenosis or thrombosis of the main coronary arteries.
    MeSH term(s) Humans ; Constriction, Pathologic ; Sensitivity and Specificity ; Magnetic Resonance Imaging/methods ; Thrombosis/diagnostic imaging ; Coronary Stenosis/diagnostic imaging
    Language English
    Publishing date 2023-11-05
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2023.111878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Long-Term Outcomes of Drug-Eluting Stent Implantation for Patients With Atherosclerotic Erectile Dysfunction not Responding to PDE-5-Inhibitors.

    Mohan, Vignes / Schönhofen, Jan / Hoppe, Hanno / Schumacher, Martin / Keo, Hak-Hong / Bechir, Markus / Kalka, Christoph / Burkhard Rn, Madlen / Diehm, Nicolas

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2023  , Page(s) 15266028231183775

    Abstract: Purpose: Endovascular therapy of erection-related arteries was shown to be a promising treatment option for patients with severe erectile dysfunction. Purpose of this study was to assess the longer-term safety and clinical success rate of endovascular ... ...

    Abstract Purpose: Endovascular therapy of erection-related arteries was shown to be a promising treatment option for patients with severe erectile dysfunction. Purpose of this study was to assess the longer-term safety and clinical success rate of endovascular revascularization of erection-related arteries with the Angiolite BTK stent in patients with arteriogenic erectile dysfunction.
    Materials and methods: A total of 147 consecutive men (63.5±9.3 years) with erectile dysfunction due to 345 atherosclerotic lesions underwent endovascular revascularization. Patients received an International Index of Erectile Function (IIEF)-15 questionnaire at 30.3±7.2 months (follow-up [FU] period no less than 18 months) after stenting. An improvement by 4 points in the erectile function domain consisting of 6 questions (IIEF-6) was defined as minimal clinically important difference (MCID).
    Results: Technical success was achieved in 99% of lesions. One major adverse event occurred after endovascular revascularization. Sixty-eight (46%) patients completed their latest FU at least 18 months following the last intervention. Minimal clinically important difference was achieved in 54% (37/68) of patients.
    Conclusions: In patients with arteriogenic erectile dysfunction not responding to phosphodiesterase-5-inhibitors (PDE-5-Is), endovascular therapy with a novel thin-strut sirolimus-eluting stent is a safe and effective treatment option during short- and longer-term FU.
    Clinical impact: Patients with severe erectile dysfunction profit greatly from endovascular therapy of erection-related arteries. Stable clinical outcomes are seen beyond a 1-year timeframe. It is proven that, the drug-eluting stent therapy for atherosclerotic ED in patients who have not responded to PDE-5-I therapy is safe and effective during longer-term follow-up.
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1177/15266028231183775
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Optional vena cava filters: indications, management, and results.

    Hoppe, Hanno

    Deutsches Arzteblatt international

    2009  Volume 106, Issue 24, Page(s) 395–402

    Abstract: Background: When anticoagulation is contraindicated or ineffective, optional vena cava filters can be used to prevent pulmonary embolism. These devices can be removed within a defined period of time or can remain in the vena cava permanently.: Methods! ...

    Abstract Background: When anticoagulation is contraindicated or ineffective, optional vena cava filters can be used to prevent pulmonary embolism. These devices can be removed within a defined period of time or can remain in the vena cava permanently.
    Methods: The status of optional vena cava filters was studied by a review of the relevant literature found in a selective Medline search from 2000 to 2008, including a Cochrane review and published guidelines.
    Results: Optional vena cava filter can be removed up to 20 weeks or even longer after insertion (depending on the filter model) in a small interventional radiological procedure if therapeutic anticoagulation has been achieved or the patient is no longer at risk for venous thromboembolism. Current studies show comparable results for optional filters and permanent filters, but there have not yet been any prospective studies comparing the two filter types.
    Conclusions: Optional vena cava filters are an important addition to the management of venous thromboembolic disease. As only limited data are available to date, the use of optional filters should be considered on an individual case basis.
    MeSH term(s) Equipment Design ; Humans ; Pulmonary Embolism/epidemiology ; Pulmonary Embolism/prevention & control ; Treatment Outcome ; Vena Cava Filters/statistics & numerical data ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/prevention & control
    Language English
    Publishing date 2009-06-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.2009.0395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Erectile dysfunction: role of computed tomography cavernosography in the diagnosis and treatment planning of venous leak.

    Hoppe, Hanno / Hirschle, Dominique / Schumacher, Martin Christian / Schönhofen, Heinz / Glenck, Michael / Kalka, Christoph / Willenberg, Torsten / Sixt, Sebastian / Müller, Dominik / Gutzeit, Andreas / Christe, Andreas / Mohan, Vignes / Diehm, Nicolas

    CVIR endovascular

    2023  Volume 6, Issue 1, Page(s) 56

    Abstract: Background: Venous leak appears to be the most common cause of vasculogenic erectile dysfunction (ED), which can be treated with venous embolization. Traditionally, conventional cavernosography was used for the diagnosis and treatment planning of venous ...

    Abstract Background: Venous leak appears to be the most common cause of vasculogenic erectile dysfunction (ED), which can be treated with venous embolization. Traditionally, conventional cavernosography was used for the diagnosis and treatment planning of venous leak. Recently, computed tomography (CT) cavernosography was introduced as a novel cross-sectional imaging method proposed to be advantageous over conventional cavernosography. We created a novel management algorithm for diagnosing venous leak including CT cavernosography as an imaging modality. In order to provide a broader basis for our management algorithm, a systematic literature review was conducted.
    Main body: In this article we systematically review relevant literature on using CT cavernosography for the diagnosis and treatment planning in ED patients with venous leak following the PRISMA selection process. Nine full-text articles were included in the review and assigned a level of evidence grade (all grade II). Two studies (2/9) compared the results of conventional cavernosography with those of CT cavernosography which was superior for site-specific venous leak identification (19.4% vs. 100%, respectively). CT cavernosography is a more detailed imaging method that is faster to perform, exposes the patient to less radiation, and requires less contrast material. In one study (1/9), CT cavernosography was used for diagnostic purposes only. Eight studies (8/9) cover both, diagnostic imaging and treatment planning including embolization (1/9) and sclerotherapy (2/9) of venous leak in patients with venogenic ED. Three studies (3/9) describe anatomical venous leak classifications that were established based on CT cavernosography findings for accurate mapping of superficial and/or deep venous leak and identification of mixed or more complex forms of venous leak present in up to 84% of patients. In addition to treatment planning, one study (1/9) used CT cavernosography also for follow-up imaging post treatment.
    Conclusion: CT cavernosography is superior to conventional cavernosography for diagnosis and treatment planning in patients with ED caused by venous leak (grade II levels of evidence). Consequently, CT cavernosography should be included in management algorithms for ED patients with suspected venous leak.
    Language English
    Publishing date 2023-11-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2520-8934
    ISSN (online) 2520-8934
    DOI 10.1186/s42155-023-00403-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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