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  1. Article: Photobiomodulation Therapy in the Management of "Black Triangles" Due to the Absence of the Gingival Interdental Papilla.

    El Mobadder, Marwan / Nammour, Samir

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54682

    Abstract: The absence of an interdental papilla, termed "black triangle," presents a challenge in aesthetic restorations. Photobiomodulation therapy (PBMT) is the non-thermal therapeutic use of light in order to positively modulate biological activity and has ... ...

    Abstract The absence of an interdental papilla, termed "black triangle," presents a challenge in aesthetic restorations. Photobiomodulation therapy (PBMT) is the non-thermal therapeutic use of light in order to positively modulate biological activity and has shown promise in tissue regeneration, wound healing, and inflammation reduction. This case report introduces a modified PBM protocol known as "hemolasertherapy" aimed at regenerating the gingival interdental papilla to fill the black triangle. In this case report, a 34-year-old female with an unaesthetic black triangle between the maxillary central incisors presented for treatment. Before surgical intervention, our suggested protocol was proposed and explained, detailing potential risks and outcomes. After proper scaling root planning, a suggested protocol with PBM was made. PBM application with a 635 nm wavelength diode laser at four points around the area between the two maxillary central incisors was made: coronal third and apical third of the papilla and mesial and distal of the papilla. Then, bleeding was provoked with a curette inside the sulcus between 11 and 21 (concerned area) by applying pressure on the junctional epithelium and the supracrestal connective tissue. After a few seconds, blood spontaneously filled the "black triangle" coronal to the interdental papilla and was left undisturbed. At this point, PBM was applied again on the same four points already described. The irradiation parameters during all PBM treatments were contact mode and continuous mode, 635 nm wavelength, spot size of 8mm
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Laser-Assisted Tongue-Tie Frenectomy for Orthodontic Purpose: To Suture or Not to Suture?

    Nammour, Samir

    Photobiomodulation, photomedicine, and laser surgery

    2019  Volume 37, Issue 7, Page(s) 381–382

    MeSH term(s) Ankyloglossia/surgery ; Humans ; Infant, Newborn ; Laser Therapy ; Lingual Frenum/surgery ; Orthodontics ; Physical Therapy Modalities ; Sutures
    Language English
    Publishing date 2019-06-10
    Publishing country United States
    Document type Editorial
    ISSN 2578-5478
    ISSN (online) 2578-5478
    DOI 10.1089/photob.2019.4647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Histological and Immunohistochemical Evaluation of Rh-BMP2: Effect on Gingival Healing Acceleration and Proliferation of Human Epithelial Cells.

    Chantiri, Mansour / Nammour, Samir / El Toum, Sami / Zeinoun, Toni

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 4

    Abstract: This study aims to histologically and immunohistochemically evaluate the effect recombinant human bone morphogenetic protein (rh-BMP2) injected in gingival tissue has on the acceleration of the epithelial migration from the wound edges and epithelial ... ...

    Abstract This study aims to histologically and immunohistochemically evaluate the effect recombinant human bone morphogenetic protein (rh-BMP2) injected in gingival tissue has on the acceleration of the epithelial migration from the wound edges and epithelial cell proliferation after implant surgery.
    Material and methods: The study includes 20 patients who underwent bilateral implant surgeries in the premolar-molar region of the mandible, followed by guided bone regeneration. Each patient received an implant in both locations, but rh-BMP2 was only on the right side. At 9 days from the surgery, a gingival biopsy was performed 3 mm distally to the last implant. In total, 20 samples were collected from the left side (control group #1) and 20 from right (test group #1). This was repeated at a 4-month interval during healing abutment placements. Tissues were processed and stained with hematoxylin-eosin and then immunohistochemically for the expression of Ki-67 and further histological examination.
    Result: Complete closure of the epithelium with new cell formation was observed in the 55% test group and 20% control group after 9 days. At 4 months, although 100% samples of all groups had complete epithelial closure, the test group showed that the epithelial cells were more organized and mature due to the increased number of blood vessels. The average number of new epithelial cells was 17.15 ± 7.545 and 16.12 ± 7.683 cells per mm in test group, respectively, at 9 days and 4 months and 10.99 ± 5.660 and 10.95 ± 5.768 in control groups.
    Conclusion: Evident from histological observations, rh-BMP-2 can accelerate the closure of gingival wounds, the healing process of epithelial gingival tissue, and the formation of epithelial cells in patients undergoing dental implant treatment.
    Language English
    Publishing date 2024-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14040459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Photodynamic Therapy with Tolonium Chloride and a Diode Laser (635 nm) in the Non-Surgical Management of Periodontitis: A Clinical Study.

    El Mobadder, Marwan / Nammour, Samir / Grzech-Leśniak, Kinga

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: This study aimed to evaluate the efficacy of photodynamic therapy (PDT) using tolonium chloride and a 635 nm diode laser as an adjunct to non-surgical periodontitis treatment, specifically scaling and root planing (SRP) alone. A total of 32 patients with ...

    Abstract This study aimed to evaluate the efficacy of photodynamic therapy (PDT) using tolonium chloride and a 635 nm diode laser as an adjunct to non-surgical periodontitis treatment, specifically scaling and root planing (SRP) alone. A total of 32 patients with a pocket probing depth > 5 mm were included in the study. Among them, 16 patients underwent SRP alone (control group), and the remaining 16 patients received SRP along with PDT (study group). The PDT procedure utilized a 635 nm diode laser (Smart M, Lasotronix, Poland) and tolonium chloride. Clinical periodontal parameters, such as the plaque index (PI), bleeding on probing (BOP), gingival recession (GR), probing pocket depth (PPD), and clinical attachment loss (CAL), were assessed before treatment (T0) and at 3 months after treatment (T3). At T3, both groups demonstrated a significant reduction in the PI, BOP, PD, and CAL compared to T0. The SRP + PDT group displayed a significant reduction in PPD (3.79 mm ± 0.35) compared to the SRP alone group (4.85 mm ± 0.42) at T3. Furthermore, the SRP + PDT group exhibited a significant reduction in CAL (5.01 ± 0.81) compared to the SRP group (5.99 ± 1.08) at T3. Within the study's limitations, it was concluded that PDT, with tolonium chloride and a 635 nm diode laser, significantly contributed to the non-surgical treatment of periodontitis.
    Language English
    Publishing date 2023-08-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chronology of the Use of the Laser Beam in Dentistry, and the State of Postgraduate University Education Programs in this Domain.

    Nammour, Samir

    Photomedicine and laser surgery

    2016  Volume 34, Issue 1, Page(s) 1–2

    MeSH term(s) Education, Dental, Graduate ; Humans ; Laser Therapy
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 2158446-1
    ISSN 1557-8550 ; 1549-5418
    ISSN (online) 1557-8550
    ISSN 1549-5418
    DOI 10.1089/pho.2015.4060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Laser-Assisted Periodontitis and Peri-Implantitis Treatments: Update and the State of the Art.

    Namour, Melanie / Nammour, Samir / Rompen, Eric

    Photobiomodulation, photomedicine, and laser surgery

    2022  Volume 40, Issue 3, Page(s) 157–158

    MeSH term(s) Humans ; Lasers ; Microbiota ; Peri-Implantitis/radiotherapy ; Periodontitis/radiotherapy
    Language English
    Publishing date 2022-02-18
    Publishing country United States
    Document type Editorial
    ISSN 2578-5478
    ISSN (online) 2578-5478
    DOI 10.1089/photob.2021.0164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Laser-Assisted Non-Surgical Treatments of Periodontitis

    Marwan El Mobadder / Amaury Namour / Samir Nammour

    Encyclopedia, Vol 3, Iss 31, Pp 458-

    2023  Volume 467

    Abstract: This entry explores the innovative use of lasers in the non-surgical treatment of periodontitis, shedding light on the advantages, effectiveness, and limitations of this approach. There has been a massive eruption of innovations and technologies to ... ...

    Abstract This entry explores the innovative use of lasers in the non-surgical treatment of periodontitis, shedding light on the advantages, effectiveness, and limitations of this approach. There has been a massive eruption of innovations and technologies to assist in the treatment of periodontal diseases over the past 30 years. The use of lasers has opened new horizons and possibilities that can enhance periodontal treatments. However, their use is not always based on validated concepts and evidence-based protocols. Hence, this entry aims to describe, summarize, and assess the available evidence on the current laser-assisted protocols in the non-surgical treatment of periodontitis. Four distinct laser-assisted approaches are addressed: (1) the use of lasers for the removal of subgingival calculus, (2) the use of lasers in photodynamic therapy/photoactivated disinfection, (3) the use of lasers in photobiomodulation therapy, and (4) the use of high-power lasers. Based on the available studies and on the current guidelines and recommendations, the use of lasers exhibits several advantages, such as the increased disinfection of periodontal pockets and the junctional epithelium and connective tissue, the removal of calculus and biofilm, and the bactericidal effect on periodontal pathogens. Moreover, photobiomodulation therapy seems to play a positive role in the management of the inflammatory process of periodontitis. Although promising, the use of lasers in the non-surgical treatment of periodontitis needs to be further investigated.
    Keywords periodontitis ; lasers ; periodontal treatment ; disinfection ; periodontal pathogens ; Science ; Q
    Subject code 621
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Effect of rh-BMP-2 in the Initiation of Neovascularization in Human Gingival Tissue: A Split-Mouth Clinical Study.

    Chantiri, Mansour / Nammour, Samir / El Toum, Sami / Zeinoun, Toni

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 12

    Abstract: The aim of this study is to evaluate the effect on the initiation of new blood vessel formation of rh-BMP-2 administration in the human gingival tissue during bone regeneration surgery.: Material and methods: The randomized controlled clinical trial ... ...

    Abstract The aim of this study is to evaluate the effect on the initiation of new blood vessel formation of rh-BMP-2 administration in the human gingival tissue during bone regeneration surgery.
    Material and methods: The randomized controlled clinical trial included twenty patients with bilateral partial edentulous of the mandibular premolar and molar region. Each patient received one implants on each side. Only one side received a 0.25 µg injection of rhBMP-2 into the gingival flap and grafted material during guided bone regeneration (GBR) for dental implantation. And the other side received GBR without injection. Three samples were collected from each patient as follows: one from the anterior area of the mandible (control group #1) collected at the time of all implant surgeries, and the two other samples during the placement of healing abutments at 4 months of follow-up, from treated side with rh-BMP-2 (test group) and untreated ones (control group #2). A total of 60 gingival samples were collected. Samples were stained with hematoxylin-eosin, and immunohistochemistry was performed with a vascular endothelial growth factor marker. The number of new vessels in each sample was counted.
    Result: Statistical analyses showed a significantly higher number of new vessels in the gingival tissue of the test group.
    Conclusions: Rh-BMP-2 injections into the gingival flap significantly improved new blood vessel formation.
    Language English
    Publishing date 2023-12-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13122298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Laser Basic Research, Clinical Use, and Innovative Teachings in Odontology.

    Brugnera Junior, Aldo / Zeinoun, Toni / Nammour, Samir

    Photobiomodulation, photomedicine, and laser surgery

    2021  Volume 39, Issue 1, Page(s) 1–3

    MeSH term(s) Lasers
    Language English
    Publishing date 2021-02-15
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2578-5478
    ISSN (online) 2578-5478
    DOI 10.1089/photob.2020.4915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effect of rh-BMP-2 in the Initiation of Neovascularization in Human Gingival Tissue

    Mansour Chantiri / Samir Nammour / Sami El Toum / Toni Zeinoun

    Life, Vol 13, Iss 12, p

    A Split-Mouth Clinical Study

    2023  Volume 2298

    Abstract: The aim of this study is to evaluate the effect on the initiation of new blood vessel formation of rh-BMP-2 administration in the human gingival tissue during bone regeneration surgery. Material and Methods: The randomized controlled clinical trial ... ...

    Abstract The aim of this study is to evaluate the effect on the initiation of new blood vessel formation of rh-BMP-2 administration in the human gingival tissue during bone regeneration surgery. Material and Methods: The randomized controlled clinical trial included twenty patients with bilateral partial edentulous of the mandibular premolar and molar region. Each patient received one implants on each side. Only one side received a 0.25 µg injection of rhBMP-2 into the gingival flap and grafted material during guided bone regeneration (GBR) for dental implantation. And the other side received GBR without injection. Three samples were collected from each patient as follows: one from the anterior area of the mandible (control group #1) collected at the time of all implant surgeries, and the two other samples during the placement of healing abutments at 4 months of follow-up, from treated side with rh-BMP-2 (test group) and untreated ones (control group #2). A total of 60 gingival samples were collected. Samples were stained with hematoxylin-eosin, and immunohistochemistry was performed with a vascular endothelial growth factor marker. The number of new vessels in each sample was counted. Result: Statistical analyses showed a significantly higher number of new vessels in the gingival tissue of the test group. Conclusions: Rh-BMP-2 injections into the gingival flap significantly improved new blood vessel formation.
    Keywords recombinant human bone morphogenic protein 2 ; vascular endothelial growth factor ; gingival tissue ; guided bone regeneration ; neovascularization ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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