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  1. Article: Oral Syphilis: A Reemerging Infection Prompting Clinicians' Alertness.

    Dybeck Udd, Sebastian / Lund, Bodil

    Case reports in dentistry

    2016  Volume 2016, Page(s) 6295920

    Abstract: Syphilis is a rare but increasing disease. Due to changing sexual habits, presentation of oral manifestations may rise. Since syphilis may mimic other oral manifestations, diagnoses can be difficult. Clinicians need to be aware that ambiguous oral ... ...

    Abstract Syphilis is a rare but increasing disease. Due to changing sexual habits, presentation of oral manifestations may rise. Since syphilis may mimic other oral manifestations, diagnoses can be difficult. Clinicians need to be aware that ambiguous oral manifestations may in fact be caused by oral syphilis. Here, we present a case of extended diagnostic delay highlighting the importance of consulting an expert in infectious diseases in case of obscure oral lesions not responding to standard treatment. Despite seven visits to six different medical doctors, a patient who presented with oral syphilis was continuously misdiagnosed. After 6 months of increasing complaints and deteriorating severity of disease, the patient was referred to an oral and maxillofacial surgeon where the correct diagnosis was determined and proper treatment initiated.
    Language English
    Publishing date 2016-05-18
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2627632-X
    ISSN 2090-6455 ; 2090-6447
    ISSN (online) 2090-6455
    ISSN 2090-6447
    DOI 10.1155/2016/6295920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Brachytherapy and osteoradionecrosis in patients with base of tongue cancer.

    Danielsson, Daniel / Hagel, Eva / Dybeck-Udd, Sebastian / Sjöström, Mats / Kjeller, Göran / Bengtsson, Martin / Abtahi, Jahan / von Beckerath, Mathias / Thor, Andreas / Halle, Martin / Friesland, Signe / Mercke, Claes / Westermark, Anders / Högmo, Anders / Munck-Wikland, Eva

    Acta oto-laryngologica

    2023  Volume 143, Issue 1, Page(s) 77–84

    Abstract: Background: Base of tongue cancer incidence and patient survival is increasing why treatment sequelae becomes exceedingly important. Osteoradionecrosis (ORN) is a late adverse effect of radiotherapy and brachytherapy (BT) could be a risk factor. ... ...

    Abstract Background: Base of tongue cancer incidence and patient survival is increasing why treatment sequelae becomes exceedingly important. Osteoradionecrosis (ORN) is a late adverse effect of radiotherapy and brachytherapy (BT) could be a risk factor. Brachytherapy is used in three out of six health care regions in Sweden.
    Aims: Investigate if patients treated in regions using BT show an increased risk for ORN and whether brachytherapy has any impact on overall survival.
    Material and methods: We used data from the Swedish Head and Neck Cancer Register between 2008-2014. Due to the nonrandomized nature of the study and possible selection bias we compared the risk for ORN in brachy vs non-brachy regions.
    Results: Fifty out of 505 patients (9.9%) developed ORN; eight of these were treated in nonbrachy regions (16%), while 42 (84%) were treated in brachy regions. Neither age, sex, TNM-classification/stage, p16, smoking, neck dissection, or chemotherapy differed between ORN and no-ORN patients. The risk for ORN was significantly higher for patients treated in brachy regions compared to non-brachy regions (HR = 2,63,
    Conclusions and significance: Brachytherapy ought to be used cautiously for selected patients or within prospective randomized studies.
    MeSH term(s) Humans ; Osteoradionecrosis/epidemiology ; Osteoradionecrosis/etiology ; Brachytherapy/adverse effects ; Tongue Neoplasms/radiotherapy ; Prospective Studies ; Head and Neck Neoplasms/complications ; Retrospective Studies
    Language English
    Publishing date 2023-01-03
    Publishing country England
    Document type Journal Article
    ISSN 1651-2251
    ISSN (online) 1651-2251
    DOI 10.1080/00016489.2022.2161627
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mandibular resection in patients with head and neck cancer: acute and long-term complications after reconstruction.

    Sjöström, Mats / Danielsson, Daniel / Munck-Wikland, Eva / Nyberg, Jan / Sandström, Karl / Thor, Andreas / Johansson, Hemming / Ceghafi, Payam / Dybeck Udd, Sebastian / Emanuelsson, Jonas / Forsberg Pettersson, Linda / Halle, Martin / Laurell, Göran

    Acta oto-laryngologica

    2022  Volume 142, Issue 1, Page(s) 78–83

    Abstract: Background: The treatment of head and neck cancer is an intensive multimodal treatment that has a great impact on the individual patient.: Aims/objectives: This study aimed to evaluate acute and long-term complications associated with mandibular ... ...

    Abstract Background: The treatment of head and neck cancer is an intensive multimodal treatment that has a great impact on the individual patient.
    Aims/objectives: This study aimed to evaluate acute and long-term complications associated with mandibular resections and reconstructions.
    Material and methods: We retrospectively retrieved data on complications and recurrences among patients that underwent mandibular resections and reconstructions for treating oral cavity cancer (
    Results: Forty-two patients that underwent reconstructions with composite grafts displayed serious complications (Clavien-Dindo ≥ IIIa). The complication rates were similar between patients treated for oral cavity cancer and patients treated for ORN. Patients that underwent a primary closure without any graft, had a significantly lower risk of complications compared to patients that underwent the other treatments. After hospitalization, 181 patients (69%) had at least one complication.
    Conclusions: A majority of patients undergoing resection and reconstruction due to oral cancer/ORN suffered from postoperative complications regardless of indication, comorbidity status or reconstruction technique. The risk of Clavien-Dindo grade IIIa-V events was significantly lower for patients treated with primary closure without grafts.
    Significance: The results from this study clarifies the importance of in-depth analyse prior to decision of treatment for patients with head and neck cancer.
    MeSH term(s) Aged ; Composite Tissue Allografts ; Female ; Free Tissue Flaps ; Head and Neck Neoplasms/surgery ; Humans ; Male ; Mandible/surgery ; Middle Aged ; Osteoradionecrosis/surgery ; Postoperative Complications/etiology ; Reconstructive Surgical Procedures/methods ; Retrospective Studies
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Journal Article
    ISSN 1651-2251
    ISSN (online) 1651-2251
    DOI 10.1080/00016489.2021.2021283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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