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Article ; Online: M13KO7 bacteriophage enables Potato Virus Y detection.

Seo, Haneul / Cho, Sang-Ho / Vo, Thuy T B / Lee, Ahlim / Cho, Sungrae / Kang, Sol / Kil, Eui-Joon / Byun, Hee-Seong / Lee, Mi-Gi / Kwon, Myung-Hee / Chung, Woo-Jae / Lee, Young-Gyu / Lee, Sukchan

Microbiology spectrum

2023 Volume 11, Issue 6, Page(s) e0144623

Abstract: Importance: In this study, we confirmed the binding of M13KO7 ... ...

Abstract	Importance: In this study, we confirmed the binding of M13KO7 to
MeSH term(s)	Bacteriophages/genetics ; Potyvirus ; Enzyme-Linked Immunosorbent Assay ; Escherichia coli/genetics ; Plant Diseases
Language	English
Publishing date	2023-10-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2807133-5
ISSN	2165-0497 ; 2165-0497
ISSN (online)	2165-0497
ISSN	2165-0497
DOI	10.1128/spectrum.01446-23
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Article ; Online: Numerical study on particle behavior in a Y-junction mixer for supercritical water hydrolysis.

Uruno, Yumi / Lee, Juwon / Jeong, Hanseob / Chung, Jaewon

Bioresource technology

2023 Volume 393, Page(s) 130072

Abstract: ... investigated the particle behavior in a Y-junction mixer using large eddy simulation coupled with a discrete ... in a vertically oriented Y-junction mixer with an upward-directed supercritical water inlet, aligning the momentum ... the temperatures close to the mixing temperature of supercritical and subcritical water within the Y-junction ...

Abstract	In the continuous-type supercritical water hydrolysis process, rapid mixing of supercritical and subcritical streams is important to maximize yield and minimize degradation from over-reaction. This work investigated the particle behavior in a Y-junction mixer using large eddy simulation coupled with a discrete phase model, aiming to optimize the supercritical hydrolysis process for biomass conversion. A series of numerical simulations analyzed the influence of the mixer's orientation, flow directions, and flow rates on effective mixing and backflow prevention. The results demonstrated that the most effective mixing occurred in a vertically oriented Y-junction mixer with an upward-directed supercritical water inlet, aligning the momentum direction of natural and forced convection effectively. Consequently, over 80% of particles reached the temperatures close to the mixing temperature of supercritical and subcritical water within the Y-junction mixing zone, indicating enhanced mixing effectiveness and potential for efficient hydrolysis. This configuration also minimized backflow.
MeSH term(s)	Water ; Hydrolysis ; Bioreactors ; Computer Simulation ; Temperature
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2023-11-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2023.130072
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Article ; Online: Versatile Use of V-Y Advancement Flap for Facial Defect Reconstruction: A Case Series in Asian Patients.

Chang, Dun-Hao / Lu, Ya-Di / Lin, Tsuo-Wu / Chang, Ke-Chung

Aesthetic plastic surgery

2024

Abstract: Background: V-Y advancement flap (VYAF) is a commonly used flap for facial reconstruction ...

Abstract	Background: V-Y advancement flap (VYAF) is a commonly used flap for facial reconstruction, but it is not popular in Asian society with limited aesthetic outcome evaluation. Objective: To demonstrate our experience of facial VYAF with the quantitative aesthetic outcome assessment. Methods and materials: From January 2013 to December 2022, patients who underwent facial VYAF reconstruction were reviewed. Postoperative photographs were collected and independently graded by three plastic surgeons, three nurses, and six non-medical personnel using Manchester scar scale (MSS). The representative preoperative images were selected for surgeons' reconstruction preferences survey. Results: Forty-eight patients (27 females and 21 males), with a mean age of 66.8 (23-97) years, were included in this study. All flaps survived with no flap necrosis. Only six patients (12.5%) developed minor postoperative complications, and they were treated conservatively and resolved uneventfully. The total MSS score was 7.8 ± 1.9 (scale of 4 [best scar] to 24 [worst scar]) and the overall scar VAS rating was 1.9 ± 1.1 (0 [best scar] to 10 [worst scar]), indicating satisfactory postoperative scar condition. From the survey of 22 plastic surgeons and 11 scenarios, VYAF was rarely chosen among other local flaps which only accounted for 8.7%. Conclusion: VYAF is an easy and safe method for facial reconstruction with low morbidity, but its usefulness is underappreciated. With a proper design and cautious dissection, we believe that good aesthetic and functional outcomes can be achieved with VYAF. Level of evidence iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	532791-x
ISSN	1432-5241 ; 0364-216X
ISSN (online)	1432-5241
ISSN	0364-216X
DOI	10.1007/s00266-023-03821-1
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Article: Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos.

Jiang, Wen-Jie / Lee, Song-Hee / Heo, Geun / Chung, Hak Jae / Cho, Eun Seok / Sa, Soo Jin / Hochi, Shinichi / Cui, Xiang-Shun

Frontiers in cell and developmental biology

2023 Volume 11, Page(s) 1238546

Abstract: Y-box binding protein 1 ( ...

Abstract	Y-box binding protein 1 (
Language	English
Publishing date	2023-10-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2737824-X
ISSN	2296-634X
ISSN	2296-634X
DOI	10.3389/fcell.2023.1238546
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Article ; Online: Correction: A 3-year follow-up study of uncut Roux-en-Y reconstruction: clinical results and outcomes.

Chung, Jae Hun / Im, Dong Won / Choi, Cheol Woong / Kim, Su Jin / Hwang, Sun-Hwi / Lee, Si-Hak

Surgical endoscopy

2023 Volume 37, Issue 7, Page(s) 5776

Language	English
Publishing date	2023-05-24
Publishing country	Germany
Document type	Published Erratum
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-023-10145-3
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Article: Evaluating the psychometric properties of the Chinese Depression Anxiety Stress Scale for Youth (DASS-Y) and DASS-21.

Cao, Cui-Hong / Liao, Xiao-Ling / Gamble, Jeffrey H / Li, Ling-Ling / Jiang, Xing-Yong / Li, Xu-Dong / Griffiths, Mark D / Chen, I-Hua / Lin, Chung-Ying

Child and adolescent psychiatry and mental health

2023 Volume 17, Issue 1, Page(s) 106

Abstract: ... Anxiety Stress Scale for Youth (DASS-Y) into Chinese, while also comparing its psychometric properties ... between the DASS-Y and the DASS-21, notably within the anxiety subscale. The proportions of individuals ... with the acceptance of a three-factor structure. Furthermore, the DASS-Y showed superior discriminant validity ...

Abstract	Background: In recognizing the need for a reliable and valid instrument to assess psychological distress among children and adolescents, the present study translated the newly developed Depression Anxiety Stress Scale for Youth (DASS-Y) into Chinese, while also comparing its psychometric properties with those of the well-established DASS-21 within a primary and middle school demographic. Methods: Utilizing a combination of convenience sampling and purposive sampling, a cohort comprising 1,507 primary and 1,131 middle school students was recruited. Rasch analysis, confirmatory factor analysis (CFA), and structural equation modeling (SEM) were used in the data analysis. Results: Significant differences were observed between the DASS-Y and the DASS-21, notably within the anxiety subscale. The proportions of individuals with clinical mood disorders identified by the two scales demonstrated a significant disparity. Both scales, following an adjustment of responses, exhibited satisfactory internal consistency and convergent validity, with the acceptance of a three-factor structure. Furthermore, the DASS-Y showed superior discriminant validity relative to the DASS-21, providing more compelling evidence regarding concurrent validity. Conclusion: Overall, the Chinese version of the DASS-Y demonstrated superior robustness to the DASS-21 in terms of psychometric properties. The findings provide initial evidence for the psychometric properties of the DASS-Y from another culture.
Language	English
Publishing date	2023-09-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2379599-2
ISSN	1753-2000
ISSN	1753-2000
DOI	10.1186/s13034-023-00655-2
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Article ; Online: Development of the Heterodyne Laser Encoder System for the X-Y Positioning Stage.

Chang, Chung-Ping / Tu, Tsung-Chun / Huang, Siang-Ruei / Wang, Yung-Cheng / Chang, Syuan-Cheng

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 17

Abstract: This investigation develops a laser encoder system based on a heterodyne laser interferometer. For eliminating geometric errors, the optical structure of the proposed encoder system was carried out with the internal zero-point method. The designed ... ...

Abstract	This investigation develops a laser encoder system based on a heterodyne laser interferometer. For eliminating geometric errors, the optical structure of the proposed encoder system was carried out with the internal zero-point method. The designed structure can eliminate the geometric errors, including positioning error, straightness error, squareness error, and Abbe error of the positioning stage. The signal processing system is composed of commercial integrated circuits (ICs). The signal type of the proposed encoding system is a differential signal that is compatible with most motion control systems. The proposed encoder system is embedded in a two-dimensional positioning stage. By the experimental results of the positioning test in the measuring range of 27 mm × 27 mm, with a resolution of 15.8 nm, the maximum values of the positioning error and standard deviation are 12.64 nm and 126.4 nm, respectively, in the positioning experiments. The result shows that the proposed encoder system can fit the positioning requirements of the optoelectronic and semiconductor industries.
Language	English
Publishing date	2021-08-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21175775
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Article ; Online: Tratamiento de la COVID-19 en Perú y Bolivia y los riesgos de la automedicación

Román, Brenda Rojas / Moscoso, Stephanie / Chung, Sun-ah / Terceros, Bianca Limpias / Álvarez-Risco, Aldo / Yáñez, Jaime A.

Repositorio Institucional - Ulima ; Universidad de Lima

2020

Abstract: ... sin que estén aprobados para esos fines. Muchos de estos medicamentos tienen un margen de seguridad pequeño y ... tienen efectos adversos muy riesgosos para la salud, por lo que requieren de receta médica y ... sobre todo, de monitoreo y seguimiento médico. Lamentablemente hay muchos casos de automedicación en Perú y Bolivia ...

Abstract	Introducción: Se están utilizando diversos fármacos para la sintomatología que causa la COVID-19 sin que estén aprobados para esos fines. Muchos de estos medicamentos tienen un margen de seguridad pequeño y tienen efectos adversos muy riesgosos para la salud, por lo que requieren de receta médica y, sobre todo, de monitoreo y seguimiento médico. Lamentablemente hay muchos casos de automedicación en Perú y Bolivia que requieren de un pronto abordaje. Objetivo: Efectuar una revisión sistemática de la literatura científica que presenta evidencias sobre la efectividad y las reacciones adversas de los fármacos que se usan en la actualidad contra la COVID-19 en Perú y Bolivia. Métodos: Investigación cualitativa a partir de la revisión sistemática de la literatura científica disponible en PubMed, así como la normativa nacional de Perú y Bolivia relacionada con etiología, epidemiología, sintomatología, los tratamientos aprobados y descontinuados por ambos países desde la agudización de la crisis de la COVID-19 y los estudios clínicos que se han completado hasta la fecha. Conclusiones: Los medicamentos usados en Perú y Bolivia para el tratamiento de la COVID19 tienen efectos secundarios y posibles riesgos a la salud de las personas que lamentablemente se automedican. Se requiere un mayor control de estos medicamentos para evitar su libre adquisición, mejorar la estrategia nacional y regional para evaluar los posibles tratamientos sintomatológicos de la COVID-19, para lo que se debe tener en cuenta la alta probabilidad de sobrevivencia de la enfermedad y el riesgo que representa el empleo de estos fármacos, lo que podría causar en el futuro serios efectos adversos a la salud pública de los dos países. Introduction: Various drugs are being used against the symptoms caused by COVID-19, without being approved for these purposes. Many of these drugs have small safety margin and very risky adverse effects on health, a reason why they require prescription and, above all, medical monitoring and follow-up. Unfortunately, there are many cases of self-medication in Peru and Bolivia that require prompt management. Objective: To carry out a systematic review of the scientific literature that presents evidence about the effectiveness and adverse reactions of the drugs currently used against COVID-19 in Peru and Bolivia. Methods: Qualitative research based on the systematic review of the scientific literature available in PubMed, as well as in the national regulations of Peru and Bolivia related to the etiology, epidemiology, symptoms, as well as treatments approved and discontinued by both countries since the exacerbation of the COVID-19 crisis and the completion of clinical studies to date. Conclusions: The drugs used in Peru and Bolivia for treating COVID-19 have side effects and possible risks to the health of people who unfortunately self-medicate. Greater control of these drugs is required to avoid their free acquisition, and to improve the national and regional strategy to evaluate the possible symptomatic treatments of COVID-19, taking into consideration the high probability of survival of the disease and the risk posed by using these drugs, which, in the future, could cause serious adverse effects on public health in the two countries.
Keywords	Pendiente ; covid19
Language	Spanish
Publisher	Editorial Ciencias Medicas
Publishing country	pe
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Actions of Neuropeptide Y on Synaptic Transmission in the Lateral Habenula.

Cheon, Myunghyun / Park, Hoyong / Rhim, Hyewon / Chung, ChiHye

Neuroscience

2019 Volume 410, Page(s) 183–190

Abstract: Neuropeptide Y is a peptide neuromodulator with protective roles including anxiolytic and ...

Abstract	Neuropeptide Y is a peptide neuromodulator with protective roles including anxiolytic and antidepressant-like effects in animal models of depression and post-traumatic stress disorder. The lateral habenula (LHb) is a brain region that encodes aversive information and is closely related with mood disorders. Although LHb neurons express NPY receptors, the physiological roles of NPY in this region remain uninvestigated. In this study, we examined the actions of NPY on synaptic transmission in the LHb using whole cell patch clamp recording. We observed that NPY inhibited excitatory neurotransmission in a subset of LHb neurons whereas potentiating in a small population of neurons. Inhibitory transmission remained unchanged by NPY application in a subset of neurons but was reduced in the majority of LHb neurons recorded. The overall outcome of NPY application was a decrease in the spontaneous firing rate of the LHb, leading to hypoactivation of the LHb. Our observations indicate that although NPY has divergent effects on excitatory and inhibitory transmission, NPY receptor activation decreases LHb activity, suggesting that the LHb may partly mediate the protective roles of NPY in the central nervous system.
MeSH term(s)	Action Potentials/drug effects ; Action Potentials/physiology ; Animals ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Habenula/drug effects ; Habenula/physiology ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/physiology ; Male ; Neuropeptide Y/pharmacology ; Rats ; Rats, Sprague-Dawley ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology
Chemical Substances	Neuropeptide Y
Language	English
Publishing date	2019-05-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	196739-3
ISSN	1873-7544 ; 0306-4522
ISSN (online)	1873-7544
ISSN	0306-4522
DOI	10.1016/j.neuroscience.2019.04.053
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Article ; Online: A 3-year follow-up study of uncut Roux-en-Y reconstruction: clinical results and outcomes.

Chung, Jae Hun / Im, Dong Won / Choi, Cheol Woong / Kim, Su Jin / Hwang, Sun-Hwi / Lee, Si-Hak

Surgical endoscopy

2022 Volume 36, Issue 10, Page(s) 7588–7596

Abstract: Background: The goal of this study was to identify the clinical outcomes of uncut Roux-en-Y ... method: uncut Roux-en-Y reconstruction (uncut RY) (n = 154) and Billroth II with Braun anastomosis (B-II ...

Abstract	Background: The goal of this study was to identify the clinical outcomes of uncut Roux-en-Y reconstruction in patients who underwent totally laparoscopic distal gastrectomy (TLDG) over 3-year follow-up. Methods: From January 2016 to December 2017, 269 patients who underwent TLDG were enrolled in the study and analyzed retrospectively. They were classified into two groups according to the reconstruction method: uncut Roux-en-Y reconstruction (uncut RY) (n = 154) and Billroth II with Braun anastomosis (B-II/Braun) (n = 115). Postoperative endoscopic findings (residual food, bile reflux, gastritis, and esophagitis) and nutritional status (body weight, serum hemoglobin, total protein, and albumin levels) were assessed every 6 months for 3 years. Results: Residual food was less frequent in the uncut RY group in the 6th month after TLDG (p = 0.022), but there were no differences between the two groups for the rest of the study period. The incidence of bile reflux and gastritis was low in the uncut RY group during all postoperative periods (all p < 0.001). In the B-II/Braun group, the frequency of reflux esophagitis was high in the 30th and 36th months after TLDG (both p < 0.001), and there were no differences between the two groups during the preceding periods. No significant differences were found with respect to nutritional status, such as body weight, serum hemoglobin, total protein, and albumin levels during all postoperative periods. Conclusions: Three-year follow-up outcomes showed that uncut RY can effectively reduce the incidence of bile reflux and gastritis in the remnant stomach compared to B-II/Braun after TLDG.
MeSH term(s)	Albumins ; Anastomosis, Roux-en-Y/methods ; Bile Reflux/etiology ; Body Weight ; Follow-Up Studies ; Gastrectomy/adverse effects ; Gastrectomy/methods ; Gastritis/etiology ; Gastritis/surgery ; Gastroenterostomy/methods ; Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies ; Stomach Neoplasms/surgery ; Treatment Outcome
Chemical Substances	Albumins
Language	English
Publishing date	2022-04-05
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639039-0
ISSN	1432-2218 ; 0930-2794
ISSN (online)	1432-2218
ISSN	0930-2794
DOI	10.1007/s00464-022-09198-7
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