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  1. Article: Comprehensive Treatment and Gene Analysis of a Male Patient with Follicular Occlusion Tetrad with Fordyce Granules.

    Liu, Boce / Wang, Wenjing / Bi, Jianhai / Huo, Ran

    Clinical, cosmetic and investigational dermatology

    2024  Volume 17, Page(s) 279–285

    Abstract: Follicular occlusion tetrad (FOT) is a chronic inflammatory skin disease that seriously affects patients' quality of life. At present, there is no standard treatment plan for FOT. We report the case of a 50-year-old male patient diagnosed as having FOT ... ...

    Abstract Follicular occlusion tetrad (FOT) is a chronic inflammatory skin disease that seriously affects patients' quality of life. At present, there is no standard treatment plan for FOT. We report the case of a 50-year-old male patient diagnosed as having FOT with Fordyce granules and type 2 diabetes mellitus. During hospitalization, the patient received comprehensive and systematic treatment. The patient healed well after surgery and the 10-month follow-up revealed no recurrence. We found eight gene mutations by whole-exome sequencing (WES) of the patient's peripheral blood.
    Language English
    Publishing date 2024-02-01
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S445823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Rare Case Report of Neonatal Neurofibromatosis Type 1 Presented with Giant Faciocervical Mass and Complicated with HIE.

    Liu, Boce / Wang, Wenjing / Bi, Jianhai / Huo, Ran

    International medical case reports journal

    2023  Volume 16, Page(s) 833–839

    Abstract: A newborn with giant faciocervical mass and presented with asphyxia during birth was admitted to the hospital. After stabilizing her vital sign, we provided the patient with image examinations and whole-exome sequencing, which revealed a heterozygous ... ...

    Abstract A newborn with giant faciocervical mass and presented with asphyxia during birth was admitted to the hospital. After stabilizing her vital sign, we provided the patient with image examinations and whole-exome sequencing, which revealed a heterozygous variation of neurofibromatosis type 1 (NF1). The final diagnosis of the patient was NF1 complicated with neonatal hypoxic-ischemic encephalopathy (NHIE). During hospitalization, the patient received comprehensive and systematic care. There was no reports of similar cases in the literature. So, this report aimed to elucidate the special clinical manifestations, diagnosis, treatment and prognosis of NF1 complicated with NHIE by analyzing the clinical data of the patient and her family and reviewing relevant literature.
    Language English
    Publishing date 2023-12-15
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2495077-4
    ISSN 1179-142X
    ISSN 1179-142X
    DOI 10.2147/IMCRJ.S446981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: PM

    Cheng, Peiyong / Chen, Yongqi / Wang, Jianhai / Han, Ziyu / Hao, De / Li, Yu / Feng, Feifei / Duan, Xuexin / Chen, Huaiyong

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 347, Page(s) 123686

    Abstract: ... ...

    Abstract PM
    MeSH term(s) Mice ; Animals ; Alveolar Epithelial Cells/metabolism ; Lung/metabolism ; Cell Differentiation ; Cellular Senescence ; Particulate Matter/metabolism
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2599: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Aged polystyrene microplastics exacerbate alopecia associated with tight junction injuries and apoptosis via oxidative stress pathway in skin.

    Li, Qian / Jiang, Lehua / Feng, Jianhai / Wang, Xinhui / Wang, Xusheng / Xu, Xuejuan / Chu, Weiwei

    Environment international

    2024  Volume 186, Page(s) 108638

    Abstract: Microplastics (MPs) are pervasive pollutants in the natural environment and contribute to increased levels of illness in both animals and humans. However, thespecific impacts of MPs on skin damage and alopeciaare not yet well understood. In this study, ... ...

    Abstract Microplastics (MPs) are pervasive pollutants in the natural environment and contribute to increased levels of illness in both animals and humans. However, thespecific impacts of MPs on skin damage and alopeciaare not yet well understood. In this study, we have examined the effects of two types of polystyrene MPs (pristine and aged) on skin and hair follicle damage in mice. UV irradiation changed the chemical and physical properties of the aged MPs, including functional groups, surface roughness, and contact angles. In both in vivo and in vitro experiments, skin and cell injuries related to oxidative stress, apoptosis, tight junctions (TJs), alopecia, mitochondrial dysfunction, and other damages were observed. Mechanistically, MPs and aged MPs can induce TJs damage via the oxidative stress pathway and inhibition of antioxidant-related proteins, and this can lead to alopecia. The regulation of cell apoptosis was also observed, and this is involved in the ROS-mediated mitochondrial signaling pathway. Importantly, aged MPs showed exacerbated toxicity, which may be due to their elevated surface irregularities and altered chemical compositions. Collectively, this study suggests a potential therapeutic approach for alopecia and hair follicle damage caused by MPs pollution.
    MeSH term(s) Alopecia/chemically induced ; Microplastics/toxicity ; Oxidative Stress/drug effects ; Apoptosis/drug effects ; Animals ; Mice ; Polystyrenes/toxicity ; Tight Junctions/drug effects ; Tight Junctions/metabolism ; Skin/drug effects ; Skin/pathology ; Hair Follicle/drug effects ; Reactive Oxygen Species/metabolism
    Chemical Substances Microplastics ; Polystyrenes ; Reactive Oxygen Species
    Language English
    Publishing date 2024-04-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2024.108638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3131: Show issues Location:
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  5. Article ; Online: A review of malaria molecular markers for drug resistance in

    Wang, Siqi / Huang, Fang / Yan, He / Yin, Jianhai / Xia, Zhigui

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1167220

    Abstract: China has now achieved the elimination of malaria, but it still faces severe challenges in the post-elimination stage. China continues to be plagued by imported malaria cases, and preventing re-transmission of imported malaria is critical. The ... ...

    Abstract China has now achieved the elimination of malaria, but it still faces severe challenges in the post-elimination stage. China continues to be plagued by imported malaria cases, and preventing re-transmission of imported malaria is critical. The effectiveness of antimalarial drugs for malaria control largely depends on the study of drug resistance markers
    MeSH term(s) Humans ; Plasmodium falciparum/genetics ; Plasmodium vivax/genetics ; Systematic Reviews as Topic ; Malaria/drug therapy ; Drug Resistance/genetics ; China/epidemiology ; Malaria, Falciparum ; Protozoan Proteins/genetics ; Protozoan Proteins/pharmacology
    Chemical Substances Protozoan Proteins
    Language English
    Publishing date 2023-05-09
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1167220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An Injectable and Antifouling Supramolecular Polymer Hydrogel with Microenvironment-Regulatory Function to Prevent Peritendinous Adhesion and Promote Tendon Repair.

    Wang, Kuan / Chen, Danyang / Wang, Zhuoya / Yang, Jianhai / Liu, Wenguang

    Macromolecular bioscience

    2023  Volume 23, Issue 10, Page(s) e2300142

    Abstract: The imbalance of extrinsic and intrinsic healing of tendon is thought to be the main cause of peritendinous adhesions. In this work, an injectable supramolecular poly(N-(2-hydroxypropyl) acrylamide) (PHPAm) hydrogel is prepared merely via side chain ... ...

    Abstract The imbalance of extrinsic and intrinsic healing of tendon is thought to be the main cause of peritendinous adhesions. In this work, an injectable supramolecular poly(N-(2-hydroxypropyl) acrylamide) (PHPAm) hydrogel is prepared merely via side chain hydrogen-bonding crosslinks. This PHPAm exhibits good antifouling and self-healing properties. The supramolecular hydrogel simultaneously loaded with Prussian blue (PB) nanoparticles and platelet lysate (PL) is explored as a functional physical barrier, which can significantly resist the adhesion of fibrin and fibroblasts, attenuate the local inflammatory response, and enhance the tenocytes activity, thus balancing extrinsic and intrinsic healing. The PHPAm hydrogel is shown to prevent peritendinous adhesions considerably by inhibiting NF-κB inflammatory pathway and TGF-β1/Smad3-mediated fibrosis pathway, thereby significantly improving tendon repair by releasing bioactive factors to regulate the tenocytes behavior. This work provides a new strategy for developing physical barriers to prevent peritendinous adhesions and promote tissue repair effectively.
    Language English
    Publishing date 2023-06-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2039130-4
    ISSN 1616-5195 ; 1616-5187
    ISSN (online) 1616-5195
    ISSN 1616-5187
    DOI 10.1002/mabi.202300142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Suspected malignant hyperthermia in a young Chinese patient undergoing a micro varicocelectomy surgery.

    Xu, Hongjiao / Wang, Zhaomin / Peng, Zhongmei / Zhang, Jianhai / Li, Xiang / Liu, Di / Qi, Jie / Li, Jinbao

    Chinese medical journal

    2023  Volume 136, Issue 17, Page(s) 2116–2118

    MeSH term(s) Humans ; Abdomen ; Dantrolene ; East Asian People ; Malignant Hyperthermia
    Chemical Substances Dantrolene (F64QU97QCR)
    Language English
    Publishing date 2023-09-05
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000002317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
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  8. Article ; Online: Customized Trajectory Optimization and Compliant Tracking Control for Passive Upper Limb Rehabilitation.

    Li, Liaoyuan / Han, Jianhai / Li, Xiangpan / Guo, Bingjing / Wang, Xinjie

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 15

    Abstract: Passive rehabilitation training in the early poststroke period can promote the reshaping of the nervous system. The trajectory should integrate the physicians' experience and the patient's characteristics. And the training should have high accuracy on ... ...

    Abstract Passive rehabilitation training in the early poststroke period can promote the reshaping of the nervous system. The trajectory should integrate the physicians' experience and the patient's characteristics. And the training should have high accuracy on the premise of safety. Therefore, trajectory customization, optimization, and tracking control algorithms are conducted based on a new upper limb rehabilitation robot. First, joint friction and initial load were identified and compensated. The admittance algorithm was used to realize the trajectory customization. Second, the improved butterfly optimization algorithm (BOA) was used to optimize the nonuniform rational B-spline fitting curve (NURBS). Then, a variable gain control strategy is designed, which enables the robot to track the trajectory well with small human-robot interaction (HRI) forces and to comply with a large HRI force to ensure safety. Regarding the return motion, an error subdivision method is designed to slow the return movement. The results showed that the customization force is less than 6 N. The trajectory tracking error is within 12 mm without a large HRI force. The control gain starts to decrease in 0.5 s periods while there is a large HRI force, thereby improving safety. With the decrease in HRI force, the real position can return to the desired trajectory slowly, which makes the patient feel comfortable.
    MeSH term(s) Humans ; Algorithms ; Movement ; Robotics/methods ; Stroke Rehabilitation ; Upper Extremity/physiology
    Language English
    Publishing date 2023-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23156953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Retinal Metabolic Profile on IMPG2 Deficiency Mice with Subretinal Lesions.

    Xu, Rong / Wang, Yekai / Du, Jianhai / Salido, Ezequiel M

    Advances in experimental medicine and biology

    2023  Volume 1415, Page(s) 457–463

    Abstract: The interphotoreceptor matrix (IPM) is the extracellular matrix between the photoreceptors and the retinal pigment epithelium (RPE). The IPM has two proteoglycans: the IPM proteoglycans 1 and 2 (IMPG1 and IMPG2, respectively). Patients with mutations on ... ...

    Abstract The interphotoreceptor matrix (IPM) is the extracellular matrix between the photoreceptors and the retinal pigment epithelium (RPE). The IPM has two proteoglycans: the IPM proteoglycans 1 and 2 (IMPG1 and IMPG2, respectively). Patients with mutations on IMPG2 develop subretinal vitelliform lesions that affect vision. We previously created an IMPG2 knockout (KO) mice model that generates subretinal lesions similar to those found in humans. These subretinal lesions in IMPG2 KO mice retinas are, in part, composed of mislocalized IMPG1. In addition, IMPG2 KO mice show microscopic IMPG1 material accumulation between the RPE and the photoreceptor outer segments. In this work we discuss the possibility that material accumulation on IMPG2 KO mice retinas affects photoreceptor metabolism. To further investigate this idea, we used targeted metabolomics to profile retinal metabolome on IMPG2 KO mice. The metabolite set enrichment analysis showed reduced glutamate metabolism, urea cycle, and galactose metabolism suggesting affected energy metabolism in mice retinas of IMPG2 KO mice with subretinal lesion.
    MeSH term(s) Animals ; Mice ; Extracellular Matrix Proteins/metabolism ; Eye Proteins/genetics ; Eye Proteins/metabolism ; Metabolome ; Mice, Knockout ; Proteoglycans ; Retina/metabolism
    Chemical Substances Extracellular Matrix Proteins ; Eye Proteins ; IMPG1 protein, mouse ; Proteoglycans
    Language English
    Publishing date 2023-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-27681-1_67
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3192: Show issues Location:
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    Einzelsignatur: Show issues

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  10. Article ; Online: Key takeaways from China’s success in eliminating malaria

    Fang Huang / Xinyu Feng / Jianhai Yin / Rubo Wang / Zhigui Xia

    BMJ Global Health, Vol 7, Iss

    leveraging existing evidence for a malaria-free world

    2022  Volume 4

    Keywords Medicine (General) ; R5-920 ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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