LIVIVO - Search results -

Search results

Result 1 - 10 of total 101

Search options

Article ; Online: The impact of microplastics on female reproduction and early life.

Yang, Jiayi / Kamstra, Jorke / Legler, Juliette / Aardema, Hilde

2023 Volume 20, Issue 2, Page(s) e20230037

Abstract: Plastic pollution in our environment is one of the most important global health concerns right now. Micro- and nanoplastics (MNPs) are taken up by both humans and animals, mainly via food and water, and can pass important epithelial barriers. Indications ...

Abstract	Plastic pollution in our environment is one of the most important global health concerns right now. Micro- and nanoplastics (MNPs) are taken up by both humans and animals, mainly via food and water, and can pass important epithelial barriers. Indications of plastics in the blood circulation have recently been shown in both humans and farm animals, but standardized methods to quantify the exact levels of MNPs to which we are exposed are currently lacking. Potential hazards of MNPs are being investigated very recently, including the impact that MNPs may have on reproduction. However, studies on mammalian reproduction are scarce, but a wealth of data from aquatic species indicates reproductive effects of MNPs. The first studies in rodent models demonstrate that MNPs reach the gonads after oral exposure and may impact offspring after maternal exposure during the gestational period. These effects may arise from the particles themselves or the presence of plastic contaminants that leach from plastics. Plastic contamination has been detected in human placentas, fetal fluid and the meconium of newborns, indicating the presence of plastics from the very first start of life. Currently there is a lack of studies that investigate the impact of MNP exposure during the periconception and embryonic period, whereas this is an extremely sensitive period that needs considerable attention with the growing amount of plastics in our environment.
Language	English
Publishing date	2023-07-24
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2227229-X
ISSN	1984-3143 ; 1984-3143
ISSN (online)	1984-3143
ISSN	1984-3143
DOI	10.1590/1984-3143-AR2023-0037
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Association between days post conception and lactation persistency in dairy cattle.

Chen, Y / Steeneveld, W / Frankena, K / Leemans, I / Aardema, H / Vos, P L A M / Nielen, M / Hostens, M

Journal of dairy science

2024

Abstract: Determining the optimal insemination moment for individual cows is complex, particularly when considering the impact of pregnancy on milk production. The effect of pregnancy on the absolute milk yield has already been reported in several studies. ... ...

Abstract	Determining the optimal insemination moment for individual cows is complex, particularly when considering the impact of pregnancy on milk production. The effect of pregnancy on the absolute milk yield has already been reported in several studies. Currently, there is limited quantitative knowledge about the association between days post conception (DPC) and lactation persistency, based on a lactation curve model, and, specifically, how persistency changes during pregnancy and relates to the days in milk at conception (DIMc). Understanding this association might provide valuable insights to determine the optimal insemination moment. This study, therefore, aimed to investigate the association between DPC and lactation persistency, with an additional focus on the influence of DIMc. Available milk production data from 2005 to 2022 were available for 23,908 cows from 87 herds located throughout the Netherlands and Belgium. Persistency was measured by a lactation curve characteristic decay, representing the time taken to halve milk production after peak yield. Decay was calculated for 8 DPC (0, 30, 60, 90, 120, 150, 180 and 210 d after DIMc) and served as the dependent variable. Independent variables included DPC, DIMc (< = 60, 61-90, 91-120, 121-150, 151-180, 181-210, > 210), parity group, DPC × parity group, DPC × DIMc and variables from 30 d before DIMc as covariates. The results showed an increase in decay, i.e., a decrease in persistency, during pregnancy for both parity groups, albeit in different ways. Specifically, from DPC 150 to DPC 210, multiparous cows showed a higher decline in persistency compared with primiparous cows. Furthermore, a later DIMc (cows conceiving later) was associated with higher persistency. Except for the early DIMc groups (DIMc < 90), DIMc does not impact the change in persistency by gestation. The findings from this study contribute to a better understanding of how DPC and DIMc during lactation influence lactation persistency, enabling more informed decision-making by farmers who wish to take persistency into account in their reproduction management.
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	242499-x
ISSN	1525-3198 ; 0022-0302
ISSN (online)	1525-3198
ISSN	0022-0302
DOI	10.3168/jds.2023-24282
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 810: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Measuring recovery in participants with a schizophrenia spectrum disorder: validation of the Individual Recovery Outcomes Counter (I.ROC).

Sportel, B Esther / Aardema, Hettie / Boonstra, Nynke / Arends, Johannes / Rudd, Bridey / Metz, Margot J / Castelein, Stynke / Pijnenborg, Gerdina H M

BMC psychiatry

2023 Volume 23, Issue 1, Page(s) 296

Abstract: Background: To improve recovery in mental health, validated instruments are needed.: Aims: This study evaluates psychometric properties of the Individual Recovery Outcomes Counter (I.ROC) in a Dutch population of participants with a schizophrenia ... ...

Abstract	Background: To improve recovery in mental health, validated instruments are needed. Aims: This study evaluates psychometric properties of the Individual Recovery Outcomes Counter (I.ROC) in a Dutch population of participants with a schizophrenia spectrum disorder (SSD). Methods: 326 participants completed the I.ROC at baseline (n = 326), six months (n = 155) and twelve months (n = 84) as part of a routine outcome assessment. Reliability, validity, sensitivity to change, and internal factor structure were examined. Results: Participants evaluated the I.ROC as comprehensive. Internal consistency of the I.ROC (α = 0.88) and test-retest reliability (r = .85, p < .001) are good. Negative moderate correlations with the total score of the PANSS (r=-.50, p < .001) and the HoNOS (r=-.52, p < .001) were found, and a small negative correlation with the FR tool (r=-.36, p < .001). Moderate positive correlation with the MANSA (r = .55, p < .001) and the RAS (r = .60, p < .001) were found. The mean total I.ROC scores increased significantly between time points (F(2,166) = 6.351, p < .005), although differences were small. Confirmatory factor analysis showed that fit indices for the one-, two-, and four-factor model are comparable. Conclusions: The I.ROC is a valid and reliable instrument, with sensitivity to change, to map recovery in participants with SSD.
MeSH term(s)	Humans ; Schizophrenia/diagnosis ; Reproducibility of Results ; Mental Health ; Psychometrics ; Factor Analysis, Statistical ; Surveys and Questionnaires
Language	English
Publishing date	2023-04-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2050438-X
ISSN	1471-244X ; 1471-244X
ISSN (online)	1471-244X
ISSN	1471-244X
DOI	10.1186/s12888-023-04763-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The effects of cow introductions on milk production and behaviour of the herd measured with sensors.

Scheurwater, Josje / Jorritsma, Ruurd / Nielen, Mirjam / Heesterbeek, Hans / van den Broek, Jan / Aardema, Hilde

The Journal of dairy research

2022 Volume 88, Issue 4, Page(s) 374–380

Abstract: This research paper addresses the hypothesis that cow introductions in dairy herds affect milk production and behaviour of animals already in the herd. In dairy farms, cows are commonly regrouped or moved. Negative effects of regroupings on the ... ...

Abstract	This research paper addresses the hypothesis that cow introductions in dairy herds affect milk production and behaviour of animals already in the herd. In dairy farms, cows are commonly regrouped or moved. Negative effects of regroupings on the introduced animals are reported in other studies. However, little is known about the effects on lactating cows in the herd. In this research a herd of 53 lactating dairy cows was divided into two groups in a cross-over design study. 25 cows were selected as focal cows for which continuous sensor data were collected. The treatment period consisted of replacing non-focal cows three times a week. Many potentially influencing factors were taken into account in the analysis. Replacement of cows in the treatment period indeed affected the focal animals. During the treatment period these cows showed increased walking and reduced rumination activity and produced less milk compared to the control period. Milk production per milking decreased in the treatment period up to 0.4 kg per milking on certain weekdays. Lying and standing behaviour were similar between the control and the treatment period. The current study suggests that cow introductions affect welfare and milk production of the cows already in the herd.
MeSH term(s)	Animals ; Cattle ; Cattle Diseases ; Dairying ; Farms ; Female ; Lactation ; Milk
Language	English
Publishing date	2022-01-24
Publishing country	England
Document type	Journal Article
ZDB-ID	242089-2
ISSN	1469-7629 ; 0022-0299
ISSN (online)	1469-7629
ISSN	0022-0299
DOI	10.1017/S0022029921000856
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1511: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Parallel-plate compression test for soft materials: confocal microscopy-assisted ferrule-top nanoindentation.

Manalili, Dexter / Berardi, Massimiliano / Aardema, Hilde / Asimaki, Konstantina / Sarmiento, Raymund / Imran Akca, B

Biomedical optics express

2022 Volume 13, Issue 2, Page(s) 824–837

Abstract: The parallel-plate compression test is one of the simplest ways to measure the mechanical properties of a material. In this test, the Young's modulus ( ...

Abstract	The parallel-plate compression test is one of the simplest ways to measure the mechanical properties of a material. In this test, the Young's modulus (
Language	English
Publishing date	2022-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.447147
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Fatty Acid Supplementation During

Aardema, H / Bertijn, I / van Tol, Hta / Rijneveld, A / Vernooij, Jcm / Gadella, B M / Vos, Plam

Frontiers in cell and developmental biology

2022 Volume 10, Page(s) 837405

Abstract: ... In ... ...

Abstract	In vitro
Language	English
Publishing date	2022-03-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2737824-X
ISSN	2296-634X
ISSN	2296-634X
DOI	10.3389/fcell.2022.837405
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: 196 Steroid concentrations in bovine follicular fluid are affected by metabolic stress

Aardema, H / Van Tol, H. T. A / Vos, P. L. A. M

Reproduction, fertility, and development. 2020, v. 32, no. 2

2020

Abstract: ... 10.1530/rep.1.00735; Aardema et al. 2011 Biol. Reprod. 85, 62-69, https://doi.org/10.1095/biolreprod ... 110.088815; Aardema et al. 2013 Biol. Reprod. 88, 164, https://doi.org/10.1095/biolreprod.112.106062 ... competence were measured during NEB, as oocyte competence and steroid production are related (Aardema et al ...

Abstract	The negative energy balance (NEB) in dairy cows, early postpartum, is related to reduced fertility. A metabolic characteristic of NEB is elevated levels of free fatty acids (NEFA) in blood and follicular fluid with an effect on the cumulus-oocyte complex (COC; Leroy et al. 2005 Reproduction 130, 485-495, https://doi.org/10.1530/rep.1.00735; Aardema et al. 2011 Biol. Reprod. 85, 62-69, https://doi.org/10.1095/biolreprod.110.088815; Aardema et al. 2013 Biol. Reprod. 88, 164, https://doi.org/10.1095/biolreprod.112.106062). In this study, we investigated the effect of elevated NEFA levels on granulosa cells and consequently steroid production during NEB. Both 17β-oestradiol (E2) and progesterone (P4) levels in follicular fluid and oocyte competence were measured during NEB, as oocyte competence and steroid production are related (Aardema et al. 2013 Theriogenology 80, 576-583, https://doi.org/10.1016/j.theriogenology.2013.05.025). Heifers were directed towards a control (CTR; n=6) or NEB group (NEB; n=6; fasting heifer model; Jorritsma et al. 2003 Theriogenology). Cycle synchronization and superstimulation were performed as previously reported; invivo matured oocytes were, by ovariectomy at 22h after the induced LH peak, individually collected from follicles (≥8 to ≤20mm) and invitro fertilized and cultured until Day 8. Levels of nonesterified fatty acids (NEFAs) in follicular fluid were, in CTR, 80μM palmitic (C16:0), 70μM stearic (C18:0), and 100μM oleic acid (C18:1) and, in NEB, 150μM C16:0, 100μM C18:0, and 200μM C18:1 (Aardema et al. 2013 Biol. Reprod. Vol, page range). Follicular fluid of individual follicles was frozen and stored at −20°C until E2 and P4 radioimmunoassay analysis. At Day 5 and 8 of culture, embryos were scored for developmental competence, according to Aardema et al. (2013 Biol. Reprod. Vol, page range). Oocytes developing to a blastocyst all originated from follicles with, formerly in control animals defined, optimal follicular fluid levels of E2 ≤0.25 μM and P4 ≥0.26 μM (Aardema et al. 2013 Theriogenology 80, 576-583, https://doi.org/10.1016/j.theriogenology.2013.05.025). Overall E2 levels in follicular fluid in NEB appeared to be lower than those in CTR. There was a reduced positive value of 0.33 (vs. 0.49 in CTR) for predicting the competence of oocytes to develop into a blastocyst, and reduced specificity of 0.26 (vs. 0.75 in CTR) for oocytes originating from follicles with optimal steroid levels in NEB. The sensitivity and negative predictive value were 1.0 in both NEB and CTR. Levels of P4 in follicular fluid were unaffected by NEB. The lower level of E2 indicates an effect of NEB on steroid synthesis in granulosa cells. Recently, it was demonstrated that invitro exposure to monounsaturated C18:1, in contrast to saturated C16:0 or C18:0, resulted in reduced E2 production and expression of CYP19A1 in granulosa cells (Sharma 2018 Endocrine Connections 8, 493-505, https://doi.org/10.1530/EC-19-0011). These data suggest that elevated levels of NEFAs, C18:1 in particular, affect the function of granulosa cells and the follicular steroid environment of the COC, in contrast to the effect of C18:1 on the COC, which appears to protect the oocyte against lipotoxic events by saturated NEFAs by massive lipid accumulation in cumulus cells (Aardema et al. 2011 Biol. Reprod. 85, 62-69, https://doi.org/10.1095/biolreprod.110.088815; Aardema et al. 2013 Biol. Reprod. 88, 164, https://doi.org/10.1095/biolreprod.112.106062). Elevated levels of C18:1 may also result in increased lipid storage in granulosa cells and could affect the steroid synthesis of cholesterol that is also stored in lipid droplets. How elevated NEFA levels during the NEB affect granulosa cells is under investigation.
Keywords	animal models ; animal reproduction ; blastocyst ; blood ; cholesterol ; dairy cows ; droplets ; energy balance ; fasting ; follicular fluid ; free fatty acids ; frozen storage ; granulosa cells ; heifers ; luteinizing hormone ; oleic acid ; oocytes ; ovariectomy ; palmitic acid ; prediction ; progesterone ; radioimmunoassays ; stearic acid ; storage temperature
Language	English
Size	p. 226-227.
Publishing place	CSIRO Publishing
Document type	Article
ZDB-ID	1019913-5
ISSN	1448-5990 ; 1031-3613
ISSN (online)	1448-5990
ISSN	1031-3613
DOI	10.1071/RDv32n2Ab196
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 5258: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials.

Thakkar, Yax / Moustakas, Holger / Aardema, Marilyn / Roy, Shambhu / Pfuhler, Stefan / Api, Anne Marie

Mutagenesis

2021 Volume 37, Issue 2, Page(s) 89–111

Abstract: In order to evaluate the utility of the 3D reconstructed skin micronucleus assay (3DRSMN) to assess clastogenic/aneugenic potential of the fragrance chemicals, a set of 22 fragrance materials were evaluated in 3DRSMN assay. These materials evaluated were ...

Abstract	In order to evaluate the utility of the 3D reconstructed skin micronucleus assay (3DRSMN) to assess clastogenic/aneugenic potential of the fragrance chemicals, a set of 22 fragrance materials were evaluated in 3DRSMN assay. These materials evaluated were also evaluated in an in vitro as well as in vivo micronucleus assay, conducted as per Organisation for Economic Co-operation and Development guidelines. The results of the RSMN assay were in 100% agreement with the in vivo micronucleus assay results. From this dataset, 18 materials were positive in an in vitro micronucleus assay but were negative in an in vivo micronucleus assay. All these 18 materials were also concluded to be negative in 3DRSMN assay, stressing the importance of the assay to help minimize misleading positive outcomes from the in vitro assay. Since the highest exposure for fragrances is through the dermal route, the RSMN assay fits the applicability domain for testing. Thus, RSMN assay is an important alternative to animal testing for characterization of the genotoxicity potential of fragrance materials.
MeSH term(s)	Animals ; DNA Damage ; Micronucleus Tests/methods ; Mutagens/toxicity ; Odorants ; Skin
Chemical Substances	Mutagens
Language	English
Publishing date	2021-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	632903-2
ISSN	1464-3804 ; 0267-8357
ISSN (online)	1464-3804
ISSN	0267-8357
DOI	10.1093/mutage/geab040
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2189: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cumulus cells protect the oocyte against saturated free fatty acids.

Aardema, Hilde / Vos, Peter L A M / Gadella, Bart M

Animal reproduction

2018 Volume 15, Issue Suppl 1, Page(s) 737–750

Abstract: In the cow a major characteristic of metabolic stress is an elevated level of plasma free fatty acid, due to increased lipid mobilization from adipose tissue. Elevated levels of free fatty acids in blood (complexed to albumin) are associated with ... ...

Abstract	In the cow a major characteristic of metabolic stress is an elevated level of plasma free fatty acid, due to increased lipid mobilization from adipose tissue. Elevated levels of free fatty acids in blood (complexed to albumin) are associated with increased lipotoxicity in non-adipose tissue. An overview is provided on the negative impact of free fatty acids and the metabolic stress imposed on the oocyte and early embryo and thus on bovine fertility. There is increasing evidence that
Language	English
Publishing date	2018-08-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2227229-X
ISSN	1984-3143 ; 1984-3143
ISSN (online)	1984-3143
ISSN	1984-3143
DOI	10.21451/1984-3143-AR2018-0063
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: An overview on how cumulus cells interact with the oocyte in a condition with elevated NEFA levels in dairy cows.

Aardema, Hilde / van Tol, Helena T A / Vos, Peter L A M

Animal reproduction science

2019 Volume 207, Page(s) 131–137

Abstract: Metabolic stress in humans and animals is associated with impaired fertility. A major characteristic of metabolic stress is elevated levels of free fatty acids (NEFAs) in blood due to mobilization of body fat reserves. Dairy cows undergo a period of ... ...

Abstract	Metabolic stress in humans and animals is associated with impaired fertility. A major characteristic of metabolic stress is elevated levels of free fatty acids (NEFAs) in blood due to mobilization of body fat reserves. Dairy cows undergo a period of metabolic stress during the peri-calving period, the so-called negative energy balance (NEB) in the early weeks postpartum. At the time of NEB, both saturated and unsaturated NEFAs are mobilized to serve as an alternative energy supply for cells, however in particular saturated NEFAs can have a detrimental effect on somatic cells. Circulating NEFAs are also reflected in the follicular fluid of ovarian follicles and hence reach the cumulus-oocyte-complex (COC), which implies a potential risk for the developing oocyte. To this end, the current review focusses on the impact of NEFAs on the quality of the oocyte.
MeSH term(s)	Animal Feed ; Animal Nutritional Physiological Phenomena ; Animals ; Cattle ; Cell Communication/physiology ; Cumulus Cells/physiology ; Dairying ; Fatty Acids, Nonesterified/blood ; Female ; Follicular Fluid/metabolism ; Lactation/metabolism ; Oocytes/physiology
Chemical Substances	Fatty Acids, Nonesterified
Language	English
Publishing date	2019-06-04
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	429674-6
ISSN	1873-2232 ; 0378-4320
ISSN (online)	1873-2232
ISSN	0378-4320
DOI	10.1016/j.anireprosci.2019.06.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 3232: Show issues
Z 80/707: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED