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  1. Article ; Online: An unusual case of retropharyngeal ectopic parathyroid adenoma.

    Silberzweig, Alex M / Xing, Monica / Mundi, Neil / Dowling, Eric / Urken, Mark L

    Ear, nose, & throat journal

    2022  , Page(s) 1455613221101934

    Language English
    Publishing date 2022-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613221101934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A novel technique for management of stenosis of the postlaryngectomy stoma with preservation of a functional tracheoesophageal puncture following tracheal resection.

    Seo, Gabriella T / Wein, Lauren E / Dowling, Eric M / Khorsandi, Azita S / Urken, Mark L

    Head & neck

    2022  Volume 44, Issue 7, Page(s) 1737–1741

    Abstract: Tracheostomal stenosis following total laryngectomy presents a serious concern for surgeons and patients. Although various techniques correct tracheostomal stenosis, none address an existing tracheoesophageal puncture (TEP). We present an approach to ... ...

    Abstract Tracheostomal stenosis following total laryngectomy presents a serious concern for surgeons and patients. Although various techniques correct tracheostomal stenosis, none address an existing tracheoesophageal puncture (TEP). We present an approach to repair tracheostomal stenosis, requiring tracheal resection, and preserve the TEP in a functional position needed for speech rehabilitation. A 62-year-old male with squamous carcinoma of the right true vocal fold underwent a salvage total laryngectomy with placement of a tracheoesophageal prosthesis. Seven years later, he developed tracheal narrowing. A tracheal resection and tracheoplasty were performed to manage the stenosis while maintaining the tracheoesophageal puncture. Six months postoperatively, the patient was well, with no stomal narrowing or trend toward collapse and uneventful healing. He achieved fluent voice easily with stomal occlusion. We present a novel surgical technique to correct for tracheostomal stenosis following total laryngectomy. Our technique allows for TEP preservation to facilitate speech rehabilitation postoperatively.
    MeSH term(s) Constriction, Pathologic/surgery ; Humans ; Laryngeal Neoplasms/surgery ; Laryngectomy/adverse effects ; Laryngectomy/rehabilitation ; Larynx, Artificial ; Male ; Middle Aged ; Punctures ; Retrospective Studies ; Surgical Stomas ; Trachea/surgery
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Postoperative Imaging Appearance of Iliac Crest Free Flaps Used for Palatomaxillary Reconstructions.

    Sandler, M L / Griffin, M / Xing, M H / Ansari, E / Khorsandi, A S / Urken, M L

    AJNR. American journal of neuroradiology

    2021  Volume 42, Issue 4, Page(s) 753–758

    Abstract: The osteomyocutaneous iliac crest free flap is a reconstructive option for segmental mandibular or complex palatomaxillary defects. Familiarity with the radiographic appearance of free flaps such as the iliac crest is necessary for the postoperative ... ...

    Abstract The osteomyocutaneous iliac crest free flap is a reconstructive option for segmental mandibular or complex palatomaxillary defects. Familiarity with the radiographic appearance of free flaps such as the iliac crest is necessary for the postoperative evaluation of patients after mandibular, maxillary, or palatal reconstructions because it allows radiologists to properly monitor and interpret the appearance of the flap over time. This study presents a retrospective review of 5 patients who underwent palatomaxillary reconstruction with an iliac crest free flap at our institution. The imaging appearances of the 5 patients were analyzed to determine the key radiographic characteristics of a healthy and successful iliac crest free flap. Radiographic fluency with the imaging appearance of the iliac crest free flap, as well as the new anatomy of the region in the postoperative period, will allow for better interpretation of the flap appearance on imaging and will prevent false identification of tumor recurrence.
    MeSH term(s) Bone Transplantation ; Free Tissue Flaps ; Humans ; Ilium/diagnostic imaging ; Ilium/surgery ; Postoperative Period ; Plastic Surgery Procedures ; Retrospective Studies
    Language English
    Publishing date 2021-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603808-6
    ISSN 1936-959X ; 0195-6108
    ISSN (online) 1936-959X
    ISSN 0195-6108
    DOI 10.3174/ajnr.A7005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Aggressive-Appearing Intratracheal Mass in an Older Woman.

    Roche, Ansley M / Griffin, Martha J / Urken, Mark L

    JAMA otolaryngology-- head & neck surgery

    2019  Volume 145, Issue 1, Page(s) 81–82

    MeSH term(s) Aged ; Choristoma/diagnostic imaging ; Choristoma/pathology ; Female ; Humans ; Magnetic Resonance Imaging ; Thyroid Gland ; Tomography, X-Ray Computed ; Tracheal Diseases/diagnostic imaging ; Tracheal Diseases/pathology
    Language English
    Publishing date 2019-01-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2018.2573
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  5. Article ; Online: Frozen Section Analysis in Head and Neck Surgical Pathology: A Narrative Review of the Past, Present, and Future of Intraoperative Pathologic Consultation.

    Urken, Mark L / Yun, Jun / Saturno, Michael P / Greenberg, Lily A / Chai, Raymond L / Sharif, Kayvon / Brandwein-Weber, Margaret

    Oral oncology

    2023  Volume 143, Page(s) 106445

    Abstract: Frozen section has remained the diagnostic gold standard for intraoperative pathological evaluation of surgical margins for head and neck specimens. While achieving tumor-free margins is of utmost importance to all head and neck surgeons, in practice, ... ...

    Abstract Frozen section has remained the diagnostic gold standard for intraoperative pathological evaluation of surgical margins for head and neck specimens. While achieving tumor-free margins is of utmost importance to all head and neck surgeons, in practice, there are numerous debates and a lack of standardization for the role and method of intraoperative pathologic consultation. This review serves as a summary guide to the historical and contemporary practice of frozen section analysis and margin mapping in head and neck cancer. In addition, this review discusses current challenges in head and neck surgical pathology, and introduces 3D scanning as a groundbreaking technology to bypass many of the pitfalls in the current frozen section workflow. The ultimate goal for all head and neck pathologists and surgeons should be to modernize practices and take advantage of new technology, such as virtual 3D specimen mapping techniques, that improves the workflow for intraoperative frozen section analysis.
    MeSH term(s) Humans ; Frozen Sections ; Head ; Neck ; Head and Neck Neoplasms/diagnosis ; Head and Neck Neoplasms/surgery ; Surgeons ; Margins of Excision
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2023.106445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: First reported PET positive, FDG avid free flap pedicle ossification and review of the literature.

    Silberzweig, Alex M / Xing, Monica H / Mundi, Neil / Matloob, Ammar / Urken, Mark L

    Clinical imaging

    2021  Volume 79, Page(s) 30–35

    Abstract: The fibular free flap (FFF) is commonly used for head and neck bony reconstruction. Ossification of the vascular pedicle has been reported but is an uncommon complication of this procedure. Ossification of the pedicle with FDG avidity has not been ... ...

    Abstract The fibular free flap (FFF) is commonly used for head and neck bony reconstruction. Ossification of the vascular pedicle has been reported but is an uncommon complication of this procedure. Ossification of the pedicle with FDG avidity has not been identified in the literature. Here we present a case of FDG avid free flap ossification seen on PET/CT imaging in a patient who developed trismus after fibular free flap reconstruction of a maxillary defect for a primary squamous cell carcinoma of the palate. The FDG avidity of the free flap ossification and trismus were both concerning for recurrent squamous cell carcinoma.
    MeSH term(s) Fluorodeoxyglucose F18 ; Free Tissue Flaps ; Humans ; Neoplasm Recurrence, Local ; Ossification, Heterotopic ; Osteogenesis ; Positron Emission Tomography Computed Tomography ; Reconstructive Surgical Procedures
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2021-04-13
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2021.03.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Thyroid cancer necrosis not evident on imaging: A cautionary case series on poorly differentiated thyroid carcinoma diagnosed only on final pathology.

    Beute, John E / Silberzweig, Alex M / Gold, Brandon S / Shaari, Ariana L / Kapustin, Danielle A / Matloob, Ammar / Dowling, Eric M / Starc, Michael T / Fan, Jun / Khorsandi, Azita S / Brandwein-Weber, Margaret / Urken, Mark L / Chai, Raymond L

    American journal of otolaryngology

    2023  Volume 45, Issue 1, Page(s) 104054

    Abstract: Objective: Poorly-differentiated thyroid cancer (PDTC) is a highly aggressive malignancy which is recently defined and understudied in the radiologic literature. Necrosis is a key histopathologic criterion for the diagnosis of PDTC. We illustrate the ... ...

    Abstract Objective: Poorly-differentiated thyroid cancer (PDTC) is a highly aggressive malignancy which is recently defined and understudied in the radiologic literature. Necrosis is a key histopathologic criterion for the diagnosis of PDTC. We illustrate the current difficulty in accurate identification of histopathologic necrosis on preoperative imaging.
    Methods: A series of seven patients with the final diagnosis of PDTC from our institution were identified. Multimodality preoperative imaging was analyzed by two head and neck radiologists. Final pathology reports were queried confirming histopathologic evidence of necrosis.
    Results: Patients presented with a wide range of preoperative imaging features. A consistent imaging appearance confirming necrosis was not identified. All patients were subsequently upstaged to PDTC following final pathological analysis.
    Conclusion: A lack of definitive evidence of necrosis on preoperative imaging does not exclude the possibility of PDTC. We demonstrate the need for further research to establish a clear methodology for the preoperative diagnosis of PDTC.
    MeSH term(s) Humans ; Thyroid Neoplasms/diagnostic imaging ; Thyroid Neoplasms/surgery ; Adenocarcinoma ; Necrosis
    Chemical Substances prolinedithiocarbamate (135467-92-4)
    Language English
    Publishing date 2023-09-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.104054
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  8. Article ; Online: Metastatic merkel cell carcinoma to the thyroid gland: Case report and review of the literature.

    Sayeed, Salmaan / Kapustin, Danielle / Rubin, Samuel J / Fan, Jun / Wiedmer, Christina / Chung, Daniel / Khorsandi, Azita / Brandwein-Weber, Margaret / Friedlander, Philip / Bakst, Richard / Ramirez, Ricardo J / Urken, Mark L

    American journal of otolaryngology

    2024  Volume 45, Issue 4, Page(s) 104278

    Abstract: Background: Merkel cell carcinoma (MCC) is an aggressive and rare neuroendocrine tumor, accounting for less than 1% of skin cancers. Metastasis primarily manifests in the cervical lymph nodes but rarely affect the thyroid.: Methods: We report a case ... ...

    Abstract Background: Merkel cell carcinoma (MCC) is an aggressive and rare neuroendocrine tumor, accounting for less than 1% of skin cancers. Metastasis primarily manifests in the cervical lymph nodes but rarely affect the thyroid.
    Methods: We report a case of primary head and neck cutaneous MCC with metastasis to the thyroid gland. A review of the literature of MCC with thyroid metastasis was conducted.
    Results: We identified five cases of MCC with thyroid metastasis. Primary sites included the distal upper and lower extremities, axilla, buttock, and groin. Treatment courses varied including thyroidectomy, immunotherapy, and expectant palliative measures. Time from initial diagnosis to thyroid metastasis ranged from four months to four years. Tissue diagnosis was achieved in 5 of 6 cases.
    Conclusions: MCC with thyroid metastasis is rare and likely represents aggressive disease. Despite advances in treatment and surveillance, outcomes for MCC remain poor. Ongoing research may establish predictors for treatment response.
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2024.104278
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  9. Article ; Online: Contemporary Osseous Reconstruction of the Mandible and the Maxilla.

    Likhterov, Ilya / Roche, Ansley M / Urken, Mark L

    Oral and maxillofacial surgery clinics of North America

    2018  Volume 31, Issue 1, Page(s) 101–116

    Abstract: Cancers of the oral cavity and paranasal sinuses often require ablative surgery with adjuvant therapy in most cases. Large, postablative defects of the mandible and the maxilla present several challenges to the reconstructive surgeon. Functional and ... ...

    Abstract Cancers of the oral cavity and paranasal sinuses often require ablative surgery with adjuvant therapy in most cases. Large, postablative defects of the mandible and the maxilla present several challenges to the reconstructive surgeon. Functional and cosmetically satisfactory restoration requires a thorough understanding of the underlying disease process, a firm grasp of the nuances of head and neck anatomy, and an ability to plan and execute a reconstruction with the most suitable tissue for each particular patient. The authors outline the components of osseous reconstruction of the facial skeleton with a bias toward techniques and approaches that are particularly useful.
    MeSH term(s) Bone Transplantation/methods ; Head and Neck Neoplasms/surgery ; Humans ; Mandibular Reconstruction/methods ; Maxilla/surgery ; Microsurgery ; Surgical Flaps
    Language English
    Publishing date 2018-06-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1316546-x
    ISSN 1558-1365 ; 1042-3699
    ISSN (online) 1558-1365
    ISSN 1042-3699
    DOI 10.1016/j.coms.2018.08.005
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  10. Article ; Online: Novel technique to prevent or correct open-mouth deformity after bilateral mandibular resection: Use of tensor fascia lata slings.

    Wein, Lauren E / O'Malley, Quinn F / Xing, Monica H / Sims, John R / Mundi, Neil / Dowling, Eric M / Buchbinder, Daniel / Urken, Mark L

    Head & neck

    2022  Volume 44, Issue 8, Page(s) 1995–2000

    Abstract: Open-mouth deformity after mandibular resection presents a challenge for surgeons and patients, contributing to significant functional and cosmetic morbidity. We present an innovative surgical technique to prevent or correct open-mouth deformity. Tensor ... ...

    Abstract Open-mouth deformity after mandibular resection presents a challenge for surgeons and patients, contributing to significant functional and cosmetic morbidity. We present an innovative surgical technique to prevent or correct open-mouth deformity. Tensor fascia lata slings were utilized in combination with maxillomandibular fixation to surgically correct or prevent open-mouth deformity in four patients who had previously undergone mandibulectomy or at the time of a contralateral mandibulectomy following prior hemimandibulectomy and reconstruction. Two patients achieved favorable outcomes, including oral competence and improved resting jaw position, while open-mouth deformity could not be corrected for one patient. Another patient remains in the early postoperative period following a secondary procedure to correct open-mouth deformity. Open-mouth deformity is a functional/aesthetic problem that has not been addressed in the literature. Use of tensor fascia lata slings to suspend the mandible is a novel approach to the surgical management of open-mouth deformity.
    MeSH term(s) Fascia Lata/transplantation ; Humans ; Mandible/surgery ; Mouth/surgery ; Reconstructive Surgical Procedures/adverse effects ; Reconstructive Surgical Procedures/methods ; Thigh/surgery
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27105
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