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Article: One-step Bilateral Reverse Shoulder Replacement for Posterior Fracture-dislocation in a Young Alcoholic.

Vitali, Matteo / Bettinelli, Giulia / Montalbano, Filippo / Salini, Vincenzo

2022 Volume 12, Issue 5, Page(s) 11–14

Abstract: Introduction: Bilateral posterior fracture-dislocations of the shoulders occur quite rarely. To the best of our knowledge, this is the first case happening to a young man subjected with bilateral reverse shoulder replacement surgery in a one-step ... ...

Abstract	Introduction: Bilateral posterior fracture-dislocations of the shoulders occur quite rarely. To the best of our knowledge, this is the first case happening to a young man subjected with bilateral reverse shoulder replacement surgery in a one-step procedure. Case report: The authors present the case of a Caucasian, 49, alcoholic, male affected by bilateral proximal humeral fracture with posterior dislocation, provoked by an epileptic seizure, and admitted to our hospital. The patient underwent one-step bilateral reverse total shoulder replacement surgery, due the comminution of the fracture and osteopenic pattern. He carried bilateral slings for 1 month after surgery, and after the post-operative radiological evaluation at 1 month, he started with progressive active physiotherapy. Conclusion: Opting for a total replacement instead of osteosynthesis is a valuable option in patients presenting with dislocation-comminuted fractures and alcohol intake induced osteoporosis, even if young.
Language	English
Publishing date	2022-02-10
Publishing country	India
Document type	Case Reports
ZDB-ID	2658169-3
ISSN	2250-0685
ISSN	2250-0685
DOI	10.13107/jocr.2022.v12.i05.2794
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Article: Additional Value of PET and CT Image-Based Features in the Detection of Occult Lymph Node Metastases in Lung Cancer: A Systematic Review of the Literature.

Guglielmo, Priscilla / Marturano, Francesca / Bettinelli, Andrea / Sepulcri, Matteo / Pasello, Giulia / Gregianin, Michele / Paiusco, Marta / Evangelista, Laura

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 13

Abstract: Lung cancer represents the second most common malignancy worldwide and lymph node (LN) involvement serves as a crucial prognostic factor for tailoring treatment approaches. Invasive methods, such as mediastinoscopy and endobronchial ultrasound-guided ... ...

Abstract	Lung cancer represents the second most common malignancy worldwide and lymph node (LN) involvement serves as a crucial prognostic factor for tailoring treatment approaches. Invasive methods, such as mediastinoscopy and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), are employed for preoperative LN staging. Among the preoperative non-invasive diagnostic methods, computed tomography (CT) and, recently, positron emission tomography (PET)/CT with fluorine-18-fludeoxyglucose ([
Language	English
Publishing date	2023-06-23
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13132153
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Article: Articular Femoral Head Fracture Management: A Meta-analysis of Literature.

Bettinelli, Giulia / Placella, Giacomo / Moharamzadeh, Désirée / Belluati, Alberto / Salini, Vincenzo

Indian journal of orthopaedics

2021 Volume 55, Issue Suppl 2, Page(s) 304–313

Abstract: Purpose: Articular fractures of the proximal femur are seldom encountered and there are few studies in literature regarding this topic. To date, only a few large series have adequate follow-up and exhaustive description of treatment and outcome, which, ... ...

Abstract	Purpose: Articular fractures of the proximal femur are seldom encountered and there are few studies in literature regarding this topic. To date, only a few large series have adequate follow-up and exhaustive description of treatment and outcome, which, however, often result incomplete and do not allow a comparison. Since there are still uncertainties and debates on which the treatment gold standard should be, the goal of the present study is to carry out a meta-analysis on type I and II Pipkin fracture management to establish the best treatment according to EBM. Methods: Studies regarding acetabular fractures of the femur head were identified from Google Scholar, Cochrane Library, Medline, ScienceDirect and PubMed; gray studies were searched from the included references' literature, and using general search engines and Social media; the query to be temporally extended from 1996 to 2020. Only comparative studies were included; we ruled out case-reports, case series, author's opinion, register databases. Results: Comparing conservative and surgical treatment, we found evidence of a better outcome choosing surgical treatment. We found a significant better outcome with open reduction internal fixation, instead of fragment excision. Comparing failure rate of surgical approaches, we found no statistically significant difference. Conclusion: Our study proves that there is evidence in favor of operative treatment rather than conservative in complete or displaced Pipkin fracture Type I + II; open reduction internal fixation should be preferred rather than fragment excision, whenever possible. Level of evidence: III. Therapeutic.
Language	English
Publishing date	2021-05-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	603194-8
ISSN	0019-5413
ISSN	0019-5413
DOI	10.1007/s43465-021-00431-4
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Article ; Online: Safety of spinal anesthesia and analysis of cerebrospinal fluid in SARS-CoV-2 pregnant women undergoing cesarean section: an observational prospective study.

Fierro, Giulia / Milan, Barbara / Bettinelli, Silvia / Bottari, Elisa / Bugada, Dario / Roncagliolo, Ilaria / Arosio, Marco / Farina, Claudio / Lorini, Ferdinando Luca

Journal of anesthesia, analgesia and critical care

2023 Volume 3, Issue 1, Page(s) 49

Abstract: Background: Systemic infection has always been considered a relative contraindication to neuraxial anesthesia, despite the fact that infectious complications are relatively uncommon. Pregnancy-related physiological changes and coronavirus disease (COVID- ...

Abstract	Background: Systemic infection has always been considered a relative contraindication to neuraxial anesthesia, despite the fact that infectious complications are relatively uncommon. Pregnancy-related physiological changes and coronavirus disease (COVID-19) neurotropic features may facilitate the virus' entry into the central nervous system. The principal aim of this study was to test the safety of spinal anesthesia in "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2)-positive pregnant women and to examine cerebrospinal fluid (CSF) characteristics. Methods: We conducted a prospective observational single-center study in asymptomatic or paucisymptomatic consecutive pregnant SARS-CoV-2 patients who underwent spinal anesthesia for cesarean section. Women with severe infection were excluded because they underwent general anesthesia. At the time of spinal anesthesia, we collected CSF samples, and then we performed a chemical-physical analysis to look for signs of inflammation and for SARS-CoV-2 genome. Results: We included 26 women. No spinal anesthesia complications were reported in the perioperative period and after 2 months. All CSF samples were crystal clear, and all physical-chemical values were within physiological ranges: the median concentration of CSF/plasma glucose ratio was 0.66, IQR 0.5500 (0.6000-0.7100), and the average CSF protein concentration value was 23.2 mg/dl (SD 4.87). In all samples, genomes of SARS-CoV-2 and other neurotropic viruses were not detected. Conclusions: Spinal anesthesia was safe in SARS-CoV-2 pregnant women with mild disease; no clinical maternal complications were detected, and no CSF changes indicative of inflammatory or infectious diseases that would compromise the safety of the procedure were found.
Language	English
Publishing date	2023-11-28
Publishing country	England
Document type	Journal Article
ISSN	2731-3786
ISSN (online)	2731-3786
DOI	10.1186/s44158-023-00135-1
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Article: Dual mobility for total hip arthroplasty revision surgery: A systematic review and metanalysis.

Giacomo, Placella / Giulia, Bettinelli / Valerio, Pace / Vincenzo, Salini / Pierluigi, Antinolfi

SICOT-J

2021 Volume 7, Page(s) 18

Abstract: Introduction: Revision THA (R-THA) is thought to have a higher complication rate if compared to primary THA. Dual Mobility (DM) implants have been designed aiming for achieving greater stability, with good clinical results. However, scarce material can ... ...

Abstract	Introduction: Revision THA (R-THA) is thought to have a higher complication rate if compared to primary THA. Dual Mobility (DM) implants have been designed aiming for achieving greater stability, with good clinical results. However, scarce material can be found about the real improvements provided by this type of implant compared to traditional implant in Revisions of Total Hip Arthroplasties. Methods: A systematic review and meta-analysis of comparative studies were performed in December 2019. This was in accordance with the guidelines of Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). Our primary outcome measure was overall survivorship and dislocation rate, either treated with a conservative method or requiring surgery. Results: Regarding the overall implant survival, we found a slight significant risk ratio, with a statistically meaningful difference between the two groups in questions in favour of the DM implant. A statistically significant difference in favour of the DM group turned out considering only the Dislocation rate Risk ratio and the aseptic loosening risk as well. No statistical difference was found between the two groups about the risk ratio of infection. Discussion: A steady increase of evidence is demonstrating the efficacy of using a DM cup system in THA revisions with low dislocation rates, but currently there is no study in the literature that demonstrates with statistically significant evidence. The main finding of the present study is that implant's Survivor and prevention of dislocation at medium follow-up showed better results with a DM if compared to a fixed-bearing cup, for Revision THA.
Language	English
Publishing date	2021-03-22
Publishing country	France
Document type	Journal Article
ISSN	2426-8887
ISSN	2426-8887
DOI	10.1051/sicotj/2021015
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Article: Orthopaedic patient workflow in CoViD-19 pandemic in Italy.

Bettinelli, Giulia / Delmastro, Elena / Salvato, Damiano / Salini, Vincenzo / Placella, Giacomo

Journal of orthopaedics

2020 Volume 22, Page(s) 158–159

Abstract: CoViD-19 epidemic started in China in late December 2019, and soon spread, turning into a pandemic. All medical specialties have soon been involved in the management of CoViD-19 patients; the daily Orthopaedic activity has been affected profoundly by ... ...

Abstract	CoViD-19 epidemic started in China in late December 2019, and soon spread, turning into a pandemic. All medical specialties have soon been involved in the management of CoViD-19 patients; the daily Orthopaedic activity has been affected profoundly by this dramatic health emergency. The present paper aims to summarize all the measures and changes that had to be made in order to avoid the healthcare system collapse in the most affected areas, and provides an operative flowchart.
Keywords	covid19
Language	English
Publishing date	2020-04-25
Publishing country	India
Document type	Journal Article
ZDB-ID	2240839-3
ISSN	0972-978X
ISSN	0972-978X
DOI	10.1016/j.jor.2020.04.006
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Article ; Online: CoViD-19 and ortho and trauma surgery: The Italian experience.

Placella, Giacomo / Salvato, Damiano / Delmastro, Elena / Bettinelli, Giulia / Salini, Vincenzo

Injury

2020 Volume 51, Issue 6, Page(s) 1403–1405

MeSH term(s)	Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Disease Transmission, Infectious/prevention & control ; Emergency Treatment/methods ; Guideline Adherence ; Health Services Research ; Hospitals, Isolation ; Humans ; Infection Control/methods ; Italy ; Orthopedics ; Pandemics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Practice Patterns, Physicians' ; SARS-CoV-2 ; Wounds and Injuries/mortality ; Wounds and Injuries/therapy
Keywords	covid19
Language	English
Publishing date	2020-04-15
Publishing country	Netherlands
Document type	Letter
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2020.04.012
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Zs.MO 10: Show issues

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Article ; Online: Pseudoparalytic shoulder in a CoViD-19-positive patient treated with CPAP: A case report.

Vitali, Matteo / Bettinelli, Giulia / Salvato, Damiano / Elena, Delmastro / Salini, Vincenzo

Trauma case reports

2020 Volume 29, Page(s) 100336

Abstract: The Authors report a case of a 46 years old man affected by severe acute respiratory syndrome caused by Novel Coronavirus 2019 and admitted to our hospital. The patient required continuous positive airway pressure therapy (CPAP) in the hospital ward and ... ...

Abstract	The Authors report a case of a 46 years old man affected by severe acute respiratory syndrome caused by Novel Coronavirus 2019 and admitted to our hospital. The patient required continuous positive airway pressure therapy (CPAP) in the hospital ward and subsequently orotracheal intubation while in intensive care unit. The patient laid in lateral decubitus position for several hours every day while receiving CPAP therapy. During the hospitalization, he reported limitation of range of motion of the left upper limb, without any history of acute or previous trauma. The clinical appearance of the arm was suggestive of pseudoparalytic shoulder. This case emphasizes the importance of proper body positioning during invasive and non-invasive mechanical ventilation in order to prevent peripheral nerve compression and further disability.
Keywords	covid19
Language	English
Publishing date	2020-07-29
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2835433-3
ISSN	2352-6440 ; 2352-6440
ISSN (online)	2352-6440
ISSN	2352-6440
DOI	10.1016/j.tcr.2020.100336
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Article ; Online: Effect of an Innovative Biofeedback Insole on Patient Rehabilitation after Total Knee Arthroplasty

Gianluca Castellarin / Michele Merlini / Giulia Bettinelli / Raffaella Riso / Edoardo Bori / Bernardo Innocenti

Applied Sciences, Vol 12, Iss 2456, p

2022 Volume 2456

Abstract: Partial weight bearing is fundamental to rehabilitation in the early stages following lower limb surgery. However, it remains debated as to how to properly achieve partial weight bearing while avoiding complications from excessive or premature load. Of ... ...

Abstract	Partial weight bearing is fundamental to rehabilitation in the early stages following lower limb surgery. However, it remains debated as to how to properly achieve partial weight bearing while avoiding complications from excessive or premature load. Of the devices currently on the market, instrumented insoles coupled with force-sensitive resistors (FSRs) are among the best options in today’s clinical practice. Still, although several of these systems have been developed in the last few years, only some have been validated, leaving insufficient information on their application in rehabilitation after total knee replacement (TKR). To address this research gap, we evaluated the performance of an innovative biofeedback insole system featuring an extremely low response time for real-time force feedback. We randomly recruited 30 patients who underwent total knee arthroplasty. All patients used the new programmable insole for partial weight bearing per post-operative rehabilitation protocol. Our results confirm their inability to perform a correct gait with low partial weight bearing (<30–50% of their bodyweight). Partial weight bearing with a correct gait in the post-operative period is not obtainable without a measuring system. This new biofeedback insole is thus one of the most indicated and can improve rehabilitation compliance, therefore allowing continual patient monitoring for faster discharge and fast-track rehabilitation.
Keywords	biofeedback ; knee arthroplasty ; partial weight bearing ; fast-track rehabilitation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	796
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Additional Value of PET and CT Image-Based Features in the Detection of Occult Lymph Node Metastases in Lung Cancer

Priscilla Guglielmo / Francesca Marturano / Andrea Bettinelli / Matteo Sepulcri / Giulia Pasello / Michele Gregianin / Marta Paiusco / Laura Evangelista

Diagnostics, Vol 13, Iss 2153, p

A Systematic Review of the Literature

2023 Volume 2153

Abstract	Lung cancer represents the second most common malignancy worldwide and lymph node (LN) involvement serves as a crucial prognostic factor for tailoring treatment approaches. Invasive methods, such as mediastinoscopy and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), are employed for preoperative LN staging. Among the preoperative non-invasive diagnostic methods, computed tomography (CT) and, recently, positron emission tomography (PET)/CT with fluorine-18-fludeoxyglucose ([ 18 F]FDG) are routinely recommended by several guidelines; however, they can both miss pathologically proven LN metastases, with an incidence up to 26% for patients staged with [ 18 F]FDG PET/CT. These undetected metastases, known as occult LN metastases (OLMs), are usually cases of micro-metastasis or small LN metastasis (shortest radius below 10 mm). Hence, it is crucial to find novel approaches to increase their discovery rate. Radiomics is an emerging field that seeks to uncover and quantify the concealed information present in biomedical images by utilising machine or deep learning approaches. The extracted features can be integrated into predictive models, as numerous reports have emphasised their usefulness in the staging of lung cancer. However, there is a paucity of studies examining the detection of OLMs using quantitative features derived from images. Hence, the objective of this review was to investigate the potential application of PET- and/or CT-derived quantitative radiomic features for the identification of OLMs.
Keywords	lung cancer ; radiomics ; deep learning ; occult lymph node metastasis ; CT ; PET/CT ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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