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Article ; Online: Return to Sport After Arthroscopic Autologous Matrix-Induced Chondrogenesis for Patients With Osteochondral Lesion of the Talus.

DʼAmbrosi, Riccardo / Villafañe, Jorge H / Indino, Cristian / Liuni, Federico M / Berjano, Pedro / Usuelli, Federico G

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

2019  Volume 29, Issue 6, Page(s) 470–475

Abstract: Objective: To determine the rate of return of patients to sport after arthroscopic autologous matrix-induced chondrogenesis (AT-AMIC) for outcomes 2 years after surgery.: Design: Retrospective observational cross-sectional study.: Setting: C.A.S.C. ...

Abstract Objective: To determine the rate of return of patients to sport after arthroscopic autologous matrix-induced chondrogenesis (AT-AMIC) for outcomes 2 years after surgery.
Design: Retrospective observational cross-sectional study.
Setting: C.A.S.C.O.-Foot and Ankle Unit, Istituto Ortopedico Galeazzi, Milan, Italy.
Patients and intervention: Twenty-six consecutive patients, 65.4% male (mean ± SD age: 33.7 ± 11.0 years), that underwent AT-AMIC procedure between 2012 and 2015 were selected retrospectively. From this population, only sporting patients at amateur's level were included. Arthroscopic autologous matrix-induced chondrogenesis was proposed in patients with pain and persistent disability.
Main outcome measures: All patients were assessed with the American Orthopaedic Foot and Ankle Score (AOFAS), physical component score of the 12-Item Short Form Health Survey (SF-12), Halasi ankle activity score, and University of California, Los Angeles (UCLA) activity scale preoperatively and at 24 months postoperatively.
Results: Overall, 80.8% of the patient group returned to the same preinjury sport. The mean follow-up was 42.6 ± 10.9 months (range from 25 to 62 months). Significant differences were observed with reference to AOFAS, SF-12, Halasi, and UCLA scores at the last follow-up in patients who had undergone AT-AMIC (all, P < 0.001).
Conclusions: A high percentage of patients return to their preinjury sport after AT-AMIC surgery.
MeSH term(s) Adult ; Arthroscopy/methods ; Athletic Injuries/physiopathology ; Athletic Injuries/surgery ; Cancellous Bone/transplantation ; Cartilage, Articular/injuries ; Cartilage, Articular/physiology ; Cartilage, Articular/surgery ; Chondrogenesis ; Collagen Type I/administration & dosage ; Collagen Type III/administration & dosage ; Cross-Sectional Studies ; Extracellular Matrix ; Female ; Follow-Up Studies ; Humans ; Male ; Retrospective Studies ; Return to Sport ; Talus/injuries ; Talus/physiology ; Talus/surgery ; Transplantation, Autologous ; Young Adult
Chemical Substances Collagen Type I ; Collagen Type III
Language English
Publishing date 2019-11-05
Publishing country United States
Document type Journal Article ; Observational Study
ZDB-ID 1062530-6
ISSN 1536-3724 ; 1050-642X
ISSN (online) 1536-3724
ISSN 1050-642X
DOI 10.1097/JSM.0000000000000560
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