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  1. Book: Development of the facial recess

    Eby, Thomas L.

    implications for cochlear implantation

    (The laryngoscope : Supplement ; 80)

    1996  

    Author's details Thomas L. Eby
    Series title The laryngoscope : Supplement ; 80
    The laryngoscope
    The laryngoscope ; Supplement
    Collection The laryngoscope
    The laryngoscope ; Supplement
    Keywords Cochlear Implants ; Temporal Bone / growth & development
    Language English
    Size 7 S. : Ill., graph. Darst.
    Publisher American Laryngological, Rhinological and Otological Soc
    Publishing place St. Louis, MO
    Publishing country United States
    Document type Book
    HBZ-ID HT007212247
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: A Simple Technique for Droplet Control During Mastoid Surgery.

    Carron, Jeffrey D / Buck, Lauren S / Harbarger, Claude F / Eby, Thomas L

    JAMA otolaryngology-- head & neck surgery

    2021  Volume 146, Issue 7, Page(s) 671–672

    MeSH term(s) Bedding and Linens ; Cadaver ; Case-Control Studies ; Humans ; Infection Control/methods ; Mastoid/surgery ; Mastoidectomy/methods ; Personal Protective Equipment
    Keywords covid19
    Language English
    Publishing date 2021-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2020.1064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Otologic and Audiologic Considerations for COVID-19.

    Eby, Thomas L / Arteaga, Alberto A / Spankovich, Christopher

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2020  Volume 163, Issue 1, Page(s) 110–111

    Abstract: The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of ... ...

    Abstract The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of masks on communication.
    MeSH term(s) Audiology/methods ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Disease Transmission, Infectious/prevention & control ; Humans ; Otolaryngology/methods ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599820928989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Achieving Mild Therapeutic Hypothermia in the Human Cochlea.

    Arteaga, Alberto A / Beatrous, Britton / Eby, Thomas L / Smith, Jeremy / Yoder, Marcus / Meritt, Ryan / Molinaro, Nicholas / Spankovich, Christopher

    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

    2023  Volume 44, Issue 5, Page(s) e338–e342

    Abstract: Objective: To determine temperature and duration of cooling necessary for achieving cochlear mild therapeutic hypothermia (MTH) via ear canal cooling using cool water and earmold attached to a Peltier device.: Study design and setting: Human temporal ...

    Abstract Objective: To determine temperature and duration of cooling necessary for achieving cochlear mild therapeutic hypothermia (MTH) via ear canal cooling using cool water and earmold attached to a Peltier device.
    Study design and setting: Human temporal bone lab study performed at the University of Mississippi Medical Center.
    Interventions: Cochlear cooling via the ear canal using water irrigation and an earmold attached to a Peltier device. Temperature analysis through implanted thermal probes within the cochlea.
    Main outcome measures: Temperature changes in the cochlea.
    Results: Irrigation of the ear canal with water resulted in achieving MTH in approximately 4 minutes using cool water (30°C) and in approximately 2 minutes using ice-chilled water. After 20 minutes, irrigation of the ear canal using cool water plateaued at a ∆2°C while cooling with ice-chilled water results in an average ∆4.5°C. We observed MTH using a medium-length earmold attached to a Peltier device after approximately 22 minutes of cooling and achieved a maximal average ∆ of 2.3°C after 60 minutes of cooling. Finally, we observed that a longer earmold (C2L) with greater proximity to the eardrum resulted in more efficient intracochlear temperature change, achieving MTH in approximately 16 minutes.
    Conclusions: MTH of the cochlea can be achieved with water-based ear canal irrigation and via a Peltier device connected to an aluminum earmold.
    MeSH term(s) Humans ; Ice ; Hypothermia, Induced/methods ; Cochlea ; Temporal Bone
    Chemical Substances Ice
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2036790-9
    ISSN 1537-4505 ; 1531-7129
    ISSN (online) 1537-4505
    ISSN 1531-7129
    DOI 10.1097/MAO.0000000000003843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Cost-effective Solution to Limit Aerosol Transmission of Infectious Agents During Mastoid Drilling-Reply.

    Carron, Jeffrey D / Buck, Lauren S / Harbarger, Claude F / Eby, Thomas L

    JAMA otolaryngology-- head & neck surgery

    2020  Volume 146, Issue 10, Page(s) 981

    MeSH term(s) Aerosols ; COVID-19 ; Cost-Benefit Analysis ; Humans ; Mastoid
    Chemical Substances Aerosols
    Language English
    Publishing date 2020-08-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2020.2412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Otologic and Audiologic Considerations for COVID-19

    Eby, Thomas L / Arteaga, Alberto A / Spankovich, Christopher

    Otolaryngol Head Neck Surg

    Abstract: The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of ... ...

    Abstract The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of masks on communication.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #244960
    Database COVID19

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  7. Article ; Online: Otologic and Audiologic Considerations for COVID-19

    Eby, Thomas L. / Arteaga, Alberto A. / Spankovich, Christopher

    Otolaryngology–Head and Neck Surgery

    2020  Volume 163, Issue 1, Page(s) 110–111

    Abstract: The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of ... ...

    Abstract The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of masks on communication.
    Keywords Surgery ; Otorhinolaryngology ; covid19
    Language English
    Publisher SAGE Publications
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599820928989
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The current status of audiologic rehabilitation for profound unilateral sensorineural hearing loss.

    Bishop, Charles E / Eby, Thomas L

    The Laryngoscope

    2010  Volume 120, Issue 3, Page(s) 552–556

    Abstract: Objectives/hypothesis: Audiologic rehabilitation of individuals with profound unilateral sensorineural hearing loss (USNHL) has traditionally been limited to the use of air-conduction contralateral routing of sound (CROS) hearing aids. Treatment for ... ...

    Abstract Objectives/hypothesis: Audiologic rehabilitation of individuals with profound unilateral sensorineural hearing loss (USNHL) has traditionally been limited to the use of air-conduction contralateral routing of sound (CROS) hearing aids. Treatment for these individuals has expanded with new applications of the bone-anchored hearing aid (BAHA), transcranial hearing aid (t-CROS), and the cochlear implant. In this article, the authors review the literature that addresses these various treatment options.
    Study design: Contemporary review
    Results: Historical information is available that describes the limited efficacy of air-conduction CROS hearing aids in lifting hearing handicap associated with USNHL. Current investigations on providing cross hearing are generally focused on use of the BAHA. Little is known at present whether new developments in hearing aid technology can improve on conventional air-conduction CROS or t-CROS approaches. Interestingly, the cochlear implant seems to be a viable option for individuals with USNHL and tinnitus who also have intact auditory nerve pathways.
    Conclusions: There is indication in the literature that BAHA provides greater relief of hearing handicap associated with USNHL than CROS hearing aids; however, both have been found to provide limited patient satisfaction and seemingly fall short of restoring true sound localization. Adequate trials have not been performed comparing BAHA with the best CROS hearing aid technology. Transcranial hearing aids and cochlear implants are experimental methods to treat USNHL and hold promise, although there remains a lack of studies available to fully support this.
    MeSH term(s) Audiology/methods ; Cochlear Implants ; Hearing Aids ; Hearing Loss, Sensorineural/rehabilitation ; Hearing Loss, Unilateral/rehabilitation ; Humans
    Language English
    Publishing date 2010-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.20735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Omicron BA.1 and BA.2 Neutralizing Activity Following Pre-Exposure Prophylaxis with Tixagevimab plus Cilgavimab in Vaccinated Solid Organ Transplant Recipients.

    Karaba, Andrew H / Kim, Jake D / Chiang, Teresa P-Y / Alejo, Jennifer L / Abedon, Aura T / Mitchell, Jonathan / Chang, Amy / Eby, Yolanda / Johnston, Trevor Scott / Aytenfisu, Tihitina / Hussey, Casey / Jefferis, Alexa / Fortune, Nicole / Abedon, Rivka / Thomas, Letitia / Warren, Daniel S / Sitaras, Ioannis / Pekosz, Andrew / Avery, Robin K /
    Massie, Allan B / Clarke, William A / Tobian, Aaron A R / Segev, Dorry L / Werbel, William A

    medRxiv : the preprint server for health sciences

    2022  

    Abstract: Neutralizing antibody responses are attenuated in many solid organ transplant recipients (SOTRs) despite SARS-CoV-2 vaccination. Pre-exposure prophylaxis (PrEP) with the monoclonal antibody combination Tixagevimab and Cilgavimab (T+C) might augment ... ...

    Abstract Neutralizing antibody responses are attenuated in many solid organ transplant recipients (SOTRs) despite SARS-CoV-2 vaccination. Pre-exposure prophylaxis (PrEP) with the monoclonal antibody combination Tixagevimab and Cilgavimab (T+C) might augment immunoprotection, yet activity against Omicron sublineages in vaccinated SOTRs is unknown. Vaccinated SOTRs who received 300+300mg T+C (either single dose or two 150+150mg doses) within a prospective observational cohort submitted pre- and post-injection samples between 1/10/2022-4/4/2022. Binding antibody (anti-receptor binding domain [RBD], Roche) and surrogate neutralization (%ACE2 inhibition; ≥20% connoting neutralizing inhibition, Meso Scale Discovery) were measured against variants including Omicron sublineages BA.1 and BA.2. Data were analyzed using the Wilcoxon matched-pairs signed-rank test and McNemar's test. Among 61 participants, median (IQR) anti-RBD increased from 424 (IQR <0.8-2322.5) to 3394.5 (IQR 1403.9-7002.5) U/ml post T+C (p<0.001). The proportion demonstrating vaccine strain neutralizing inhibition increased from 46% to 100% post-T+C (p<0.001). BA.1 neutralization was low and did not increase (8% to 16% of participants post-T+C, p=0.06). In contrast, BA.2 neutralization increased from 7% to 72% of participants post-T+C (p<0.001). T+C increased anti-RBD levels, yet BA.1 neutralizing activity was minimal. Encouragingly, BA.2 neutralization was augmented and in the current variant climate T+C PrEP may serve as a useful complement to vaccination in high-risk SOTRs.
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2022.05.24.22275467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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