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  1. Article ; Online: Memories of ICU stay in patients admitted for severe COVID-19.

    Salve, Giulia / Mongodi, Silvia / Mangiagalli, Matteo / Tintim Lobato, Carolina / Mojoli, Francesco

    Intensive care medicine

    2024  Volume 50, Issue 4, Page(s) 602–604

    MeSH term(s) Humans ; COVID-19 ; Critical Care ; Intensive Care Units ; Patients ; Hospitalization
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07365-z
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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Setting positive end-expiratory pressure: using the pressure-volume curve.

    Mojoli, Francesco / Pozzi, Marco / Arisi, Eric

    Current opinion in critical care

    2023  Volume 30, Issue 1, Page(s) 35–42

    Abstract: Purpose of review: To discuss the role of pressure-volume curve (PV curve) in exploring elastic properties of the respiratory system and setting mechanical ventilator to reduce ventilator-induced lung injury.: Recent findings: Nowadays, quasi-static ... ...

    Abstract Purpose of review: To discuss the role of pressure-volume curve (PV curve) in exploring elastic properties of the respiratory system and setting mechanical ventilator to reduce ventilator-induced lung injury.
    Recent findings: Nowadays, quasi-static PV curves and loops can be easily obtained and analyzed at the bedside without disconnection of the patient from the ventilator. It is shown that this tool can provide useful information to optimize ventilator setting. For example, PV curves can assess for patient's individual potential for lung recruitability and also evaluate the risk for lung injury of the ongoing mechanical ventilation setting.
    Summary: In conclusion, PV curve is an easily available bedside tool: its correct interpretation can be extremely valuable to enlighten potential for lung recruitability and select a high or low positive end-expiratory pressure (PEEP) strategy. Furthermore, recent studies have shown that PV curve can play a significant role in PEEP and driving pressure fine tuning: clinical studies are needed to prove whether this technique will improve outcome.
    MeSH term(s) Humans ; Positive-Pressure Respiration/methods ; Respiration, Artificial/adverse effects ; Respiration, Artificial/methods ; Lung ; Ventilator-Induced Lung Injury/prevention & control ; Ventilators, Mechanical
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000001127
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    Zs.A 4999: Show issues Location:
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  3. Article ; Online: The Importance of Real-Time Assessment of Chest Compression Efficacy in Cardiac Arrest.

    Romito, Giovanni / Colombo, Costanza Natalia Julia / Mazza, Giovanni Maria / Mojoli, Francesco / Tavazzi, Guido

    Chest

    2023  Volume 163, Issue 3, Page(s) e129–e131

    MeSH term(s) Humans ; Heart Arrest/therapy ; Cardiopulmonary Resuscitation
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2022.07.037
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    Ui III Zs.45: Show issues Location:
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  4. Article ; Online: Lung ultrasound training: how short is too short? observational study on the effects of a focused theoretical training for novice learners.

    Mongodi, Silvia / Arioli, Raffaella / Quaini, Attilio / Grugnetti, Giuseppina / Grugnetti, Anna Maria / Mojoli, Francesco

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 166

    Abstract: Background: Lung ultrasound has been increasingly used in the last years for the assessment of patients with respiratory diseases; it is considered a simple technique, now spreading from physicians to other healthcare professionals as nurses and ... ...

    Abstract Background: Lung ultrasound has been increasingly used in the last years for the assessment of patients with respiratory diseases; it is considered a simple technique, now spreading from physicians to other healthcare professionals as nurses and physiotherapists, as well as to medical students. These providers may require a different training to acquire lung ultrasound skills, since they are expected to have no previous experience with ultrasound. The aim of the study was to assess the impact of a short theoretical training focused on lung ultrasound pattern recognition in a population of novice nurse learners with no previous experience with ultrasound.
    Methods: We included the nurses attending a critical care advanced course for nurses performed at the University of Pavia. Images' interpretation skills were tested on two slide sets (a 25-clip set focused on B-pattern recognition and a 25-clip set focused on identification of pleural movement as lung sliding, lung pulse, lung point, no movement) before and after three 30-minute teaching modules dedicated to general ultrasound principles, B-lines assessment and lung sliding assessment. A cut off of 80% was considered acceptable for correctly interpreted images after this basic course.
    Results: 22 nurses were enrolled (age 26.0 [24.0-28.0] years; men 4 (18%)); one nurse had previous experience with other ultrasound techniques, none of them had previous experience with lung ultrasound. After the training, the number of correctly interpreted clips improved from 3.5 [0.0-13.0] to 22.0 [19.0-23.0] (p < 0.0001) for B-pattern and from 0.5 [0.0-2.0] to 8.5 [6.0-12.0] (p < 0.0001) for lung sliding assessment. The number of correct answers for B-pattern recognition was significantly higher than for lung sliding assessment, both before (3.5 [0.0-13.0] vs. 0.5 [0.0-2.0]; p = 0.0036) and after (22.0 [19.0-23.0] vs. 8.5 [6.0-12.0]; p < 0.0001) the training. After the training, nurses were able to correctly recognize the presence or the absence of a B-pattern in 84.2 ± 10.3% of cases; lung sliding was correctly assessed in 37.1 ± 15.3% of cases.
    Conclusions: Lung ultrasound is considered a simple technique; while a short, focused training significantly improves B-pattern recognition, lung sliding assessment may require a longer training for novice learners.
    Trial registration: Not applicable.
    MeSH term(s) Male ; Humans ; Adult ; Lung/diagnostic imaging ; Ultrasonography ; Physicians
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05148-0
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  5. Article ; Online: Cerebral flow variation at different intra-aortic balloon settings in cardiogenic shock.

    Colombo, Costanza Natalia Julia / Guglielmi, Angelo / Mojoli, Francesco / Tavazzi, Guido

    European heart journal. Cardiovascular Imaging

    2022  Volume 23, Issue 6, Page(s) e270

    MeSH term(s) Aorta ; Humans ; Intra-Aortic Balloon Pumping ; Myocardial Infarction ; Shock, Cardiogenic/diagnostic imaging ; Shock, Cardiogenic/therapy
    Language English
    Publishing date 2022-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jeac054
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    Zs.A 5614: Show issues Location:
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  6. Article ; Online: The weaning from mechanical ventilation: a comprehensive ultrasound approach.

    Santangelo, Erminio / Mongodi, Silvia / Bouhemad, Bélaid / Mojoli, Francesco

    Current opinion in critical care

    2022  Volume 28, Issue 3, Page(s) 322–330

    Abstract: Purpose of review: Due to heart, lung and diaphragm interactions during weaning from mechanical ventilation, an ultrasound integrated approach may be useful in the detection of dysfunctions potentially leading to weaning failure. In this review, we will ...

    Abstract Purpose of review: Due to heart, lung and diaphragm interactions during weaning from mechanical ventilation, an ultrasound integrated approach may be useful in the detection of dysfunctions potentially leading to weaning failure. In this review, we will summarize the most recent advances concerning the ultrasound applications relevant to the weaning from mechanical ventilation.
    Recent findings: The role of ultrasonographic examination of heart, lung and diaphragm has been deeply investigated over the years. Most recent findings concern the ability of lung ultrasound in detecting weaning induced pulmonary edema during spontaneous breathing trial. Furthermore, in patients at high risk of cardiac impairments, global and anterolateral lung ultrasound scores have been correlated with weaning and extubation failure, whereas echocardiographic indexes were not. For diaphragmatic ultrasound evaluation, new indexes have been proposed for the evaluation of diaphragm performance during weaning, but further studies are needed to validate these results.
    Summary: The present review summarizes the potential role of ultrasonography in the weaning process. A multimodal integrated approach allows the clinician to comprehend the pathophysiological processes of weaning failure.
    MeSH term(s) Airway Extubation ; Diaphragm/diagnostic imaging ; Humans ; Respiration, Artificial/adverse effects ; Ultrasonography/methods ; Ventilator Weaning/adverse effects ; Ventilator Weaning/methods
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000941
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    Zs.A 4999: Show issues Location:
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  7. Article ; Online: Echocardiography in Ventricular Fibrillation: Straight to the Diagnosis.

    Colombo, Costanza Natalia Julia / Dammassa, Valentino / Bagliani, Alessandro / Mojoli, Francesco / Tavazzi, Guido

    Chest

    2022  Volume 162, Issue 1, Page(s) e57–e60

    MeSH term(s) Arrhythmias, Cardiac ; Atrial Fibrillation ; Echocardiography ; Humans ; Ventricular Fibrillation/diagnostic imaging
    Language English
    Publishing date 2022-07-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.08.084
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  8. Article: Superior vena cava Candida krusei septic thrombophlebitis in an ARDS patient on ECMO, with an unusual late complication.

    Iskandar, Elizabeth / Cavanna, Caterina / Mollaschi, Eva Maria Giada / Trani, Ruben Mattia / Mojoli, Francesco / Amatu, Alessandro

    The new microbiologica

    2023  Volume 46, Issue 1, Page(s) 90–94

    Abstract: Candida-related bloodstream infections (BSIs) represent a severe condition associated with health care in the critical patient, with an increasing incidence of Candida non-albicans species. These infections could lead to several and unusual complications ...

    Abstract Candida-related bloodstream infections (BSIs) represent a severe condition associated with health care in the critical patient, with an increasing incidence of Candida non-albicans species. These infections could lead to several and unusual complications in high-risk patients due to various factors, including a prolonged hospital stay and invasive medical interventions. Here we report a case of a Candida krusei septic thrombophlebitis in an ARDS patient admitted to the ICU, complicated by a late onset prostatic abscess. To our knowledge, our patient represents the first reported case of a prostatic abscess due to Candida krusei treated with pharmacological therapy alone.
    MeSH term(s) Humans ; Abscess ; Extracorporeal Membrane Oxygenation ; Vena Cava, Superior ; Candida albicans ; Candidiasis/complications ; Candidiasis/drug therapy ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy
    Language English
    Publishing date 2023-02-09
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 756168-4
    ISSN 1121-7138 ; 0391-5352
    ISSN 1121-7138 ; 0391-5352
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  9. Article ; Online: Intra-aortic balloon pump weaning strategy: rate or volume? Look at the coronary perfusion flow!

    Colombo, Costanza Natalia Julia / Dammassa, Valentino / Mojoli, Francesco / Tavazzi, Guido

    European heart journal. Cardiovascular Imaging

    2021  Volume 23, Issue 2, Page(s) e90

    MeSH term(s) Humans ; Intra-Aortic Balloon Pumping ; Perfusion ; Weaning
    Language English
    Publishing date 2021-10-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jeab203
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  10. Article ; Online: COVID-19, End-Stage Heart Failure and Outcome: A Word of Caution in Determining the Causal Link.

    Tavazzi, Guido / Corradi, Francesco / Mojoli, Francesco / Hussain, Arif / Via, Gabriele

    JACC. Heart failure

    2020  Volume 8, Issue 7, Page(s) 598–599

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Heart Failure ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2020.04.014
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