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  1. Book: Kristin Lavransdatter

    Undset, Sigrid / Archer, Charles / Scott, T. S

    (Borzoi books)

    1944  

    Title translation Kristin Lavransdatter <engl.>
    Title variant The bridal wreath ; The cross ; The mistress of Husaby
    Author's details Sigrid Undset. [Transl. by Charles Archer and T. S. Scott]
    Series title Borzoi books
    Language English
    Size 1065 S., 8°
    Edition 4. pr
    Publisher Knopf
    Publishing place New York
    Document type Book
    Note Enth.: The bridal wreath. - The mistress of Husaby. - The cross
    Database Former special subject collection: coastal and deep sea fishing

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  2. Article ; Online: Correction to: Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report.

    Conners, Kristin / Woods, Scott E / Webb, Michael

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 481

    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04217-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction to

    Kristin Conners / Scott E. Woods / Michael Webb

    Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-

    Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report

    2023  Volume 1

    Keywords Medicine ; R
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Mating activates neuroendocrine pathways signaling hunger in

    Laturney, Meghan / Sterne, Gabriella R / Scott, Kristin

    eLife

    2023  Volume 12

    Abstract: Mated females reallocate resources to offspring production, causing changes to nutritional requirements and challenges to energy homeostasis. Although observed across species, the neural and endocrine mechanisms that regulate the nutritional needs of ... ...

    Abstract Mated females reallocate resources to offspring production, causing changes to nutritional requirements and challenges to energy homeostasis. Although observed across species, the neural and endocrine mechanisms that regulate the nutritional needs of mated females are not well understood. Here, we find that mated
    MeSH term(s) Animals ; Male ; Female ; Drosophila ; Drosophila melanogaster/physiology ; Hunger ; Reproduction/physiology ; Sugars ; Sexual Behavior, Animal
    Chemical Substances Sugars
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.85117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Biomechanical Modeling of Cesarean Section Scars and Scar Defects.

    Scott, Adrienne K / Louwagie, Erin M / Myers, Kristin M / Oyen, Michelle L

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Uterine rupture is an intrinsically biomechanical process associated with high maternal and fetal mortality. A previous Cesarean section (C-section) is the main risk factor for uterine rupture in a subsequent pregnancy due to tissue failure at the scar ... ...

    Abstract Uterine rupture is an intrinsically biomechanical process associated with high maternal and fetal mortality. A previous Cesarean section (C-section) is the main risk factor for uterine rupture in a subsequent pregnancy due to tissue failure at the scar region. Finite element modeling of the uterus and scar tissue presents a promising method to further understand and predict uterine ruptures. Using patient dimensions of an at-term uterus, a C-section scar was modeled with an applied intrauterine pressure to study how scars affect uterine stress. The scar positioning and uterine thickness were varied, and a defect was incorporated into the scar region. The modeled stress distributions confirmed clinical observations as the increased regions of stress due to scar positioning, thinning of the uterine walls, and the presence of a defect are consistent with clinical observations of features that increase the risk of uterine rupture.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.11.03.565565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Serotonergic neurons translate taste detection into internal nutrient regulation.

    Yao, Zepeng / Scott, Kristin

    Neuron

    2022  Volume 110, Issue 6, Page(s) 1036–1050.e7

    Abstract: The nervous and endocrine systems coordinately monitor and regulate nutrient availability to maintain energy homeostasis. Sensory detection of food regulates internal nutrient availability in a manner that anticipates food intake, but sensory pathways ... ...

    Abstract The nervous and endocrine systems coordinately monitor and regulate nutrient availability to maintain energy homeostasis. Sensory detection of food regulates internal nutrient availability in a manner that anticipates food intake, but sensory pathways that promote anticipatory physiological changes remain unclear. Here, we identify serotonergic (5-HT) neurons as critical mediators that transform gustatory detection by sensory neurons into the activation of insulin-producing cells and enteric neurons in Drosophila. One class of 5-HT neurons responds to gustatory detection of sugars, excites insulin-producing cells, and limits consumption, suggesting that they anticipate increased nutrient levels and prevent overconsumption. A second class of 5-HT neurons responds to gustatory detection of bitter compounds and activates enteric neurons to promote gastric motility, likely to stimulate digestion and increase circulating nutrients upon food rejection. These studies demonstrate that 5-HT neurons relay acute gustatory detection to divergent pathways for longer-term stabilization of circulating nutrients.
    MeSH term(s) Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/physiology ; Nutrients ; Serotonergic Neurons/metabolism ; Taste/physiology
    Chemical Substances Drosophila Proteins
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 808167-0
    ISSN 1097-4199 ; 0896-6273
    ISSN (online) 1097-4199
    ISSN 0896-6273
    DOI 10.1016/j.neuron.2021.12.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Gustatory Processing in Drosophila melanogaster.

    Scott, Kristin

    Annual review of entomology

    2018  Volume 63, Page(s) 15–30

    Abstract: The ability to identify nutrient-rich food and avoid toxic substances is essential for an animal's survival. Although olfaction and vision contribute to food detection, the gustatory system acts as a final checkpoint control for food acceptance or ... ...

    Abstract The ability to identify nutrient-rich food and avoid toxic substances is essential for an animal's survival. Although olfaction and vision contribute to food detection, the gustatory system acts as a final checkpoint control for food acceptance or rejection. The vinegar fly Drosophila melanogaster tastes many of the same stimuli as mammals and provides an excellent model system for comparative studies of taste detection. The relative simplicity of the fly brain and behaviors, along with the molecular genetic and functional approaches available in this system, allow the examination of gustatory neural circuits from sensory input to motor output. This review discusses the molecules and cells that detect taste compounds in the periphery and the circuits that process taste information in the brain. These studies are providing insight into how the detection of taste compounds regulates feeding decisions.
    MeSH term(s) Animals ; Central Nervous System/metabolism ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Feeding Behavior ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Sensory Receptor Cells/metabolism ; Taste
    Chemical Substances Drosophila Proteins ; Receptors, Cell Surface ; gustatory receptor, Drosophila
    Language English
    Publishing date 2018-01-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207927-6
    ISSN 1545-4487 ; 0066-4170
    ISSN (online) 1545-4487
    ISSN 0066-4170
    DOI 10.1146/annurev-ento-020117-043331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Editorial overview: Systems neuroscience.

    Feldman, Dan / Scott, Kristin

    Current opinion in neurobiology

    2020  Volume 64, Page(s) iii

    MeSH term(s) Neurosciences
    Language English
    Publishing date 2020-11-11
    Publishing country England
    Document type Editorial
    ZDB-ID 1078046-4
    ISSN 1873-6882 ; 0959-4388
    ISSN (online) 1873-6882
    ISSN 0959-4388
    DOI 10.1016/j.conb.2020.10.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Patient Anxiety Related to Patient-Perceived Delays in Surgical Treatment of Skin Cancer.

    Daly, Caroline M / Scott, Jeffrey F / Bibee, Kristin P

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2023  Volume 49, Issue 4, Page(s) 352–354

    Abstract: Background: Patients undergoing dermatologic surgery report higher anxiety levels than those undergoing nonsurgical treatments. However, little is known about the association between patient-perceived delays in skin cancer surgery and patient-reported ... ...

    Abstract Background: Patients undergoing dermatologic surgery report higher anxiety levels than those undergoing nonsurgical treatments. However, little is known about the association between patient-perceived delays in skin cancer surgery and patient-reported anxiety.
    Objective: To examine the relationship between patient-perceived delays in surgery and patient-reported anxiety.
    Methods materials: Patients undergoing wide local excision or Mohs micrographic surgery were recruited to complete a survey to assess perception of surgical delay and anxiety related to skin cancer surgery using the validated Psychosocial Screen for Cancer-Revised. Demographic and surgical characteristics were collected through chart review. Chi-square and Student t -tests were used to compare demographic and surgical information between patients who did and did not perceive a surgical delay. Differences in anxiety and depression scores for patients who did and did not report a delay were assessed using univariate and multivariate regressions.
    Results: Twenty-seven percent ( N = 33) of patients perceived a surgical delay. Perception of surgical delay was associated with increased time between biopsy and surgery ( p = .0001) and increased self-reported anxiety scores after controlling for various demographic and surgical factors ( p = .038).
    Conclusion: Patient-perceived delays in dermatologic surgery are associated with increased time to surgery and patient-reported anxiety.
    MeSH term(s) Humans ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology ; Anxiety/etiology ; Anxiety/psychology ; Skin/pathology ; Mohs Surgery/adverse effects ; Mohs Surgery/psychology ; Biopsy
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000003716
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mating activates neuroendocrine pathways signaling hunger in Drosophila females

    Meghan Laturney / Gabriella R Sterne / Kristin Scott

    eLife, Vol

    2023  Volume 12

    Abstract: Mated females reallocate resources to offspring production, causing changes to nutritional requirements and challenges to energy homeostasis. Although observed across species, the neural and endocrine mechanisms that regulate the nutritional needs of ... ...

    Abstract Mated females reallocate resources to offspring production, causing changes to nutritional requirements and challenges to energy homeostasis. Although observed across species, the neural and endocrine mechanisms that regulate the nutritional needs of mated females are not well understood. Here, we find that mated Drosophila melanogaster females increase sugar intake, which is regulated by the activity of sexually dimorphic insulin receptor (Lgr3) neurons. In virgins, Lgr3+ cells have reduced activity as they receive inhibitory input from active, female-specific pCd-2 cells, restricting sugar intake. During copulation, males deposit sex peptide into the female reproductive tract, which silences a three-tier mating status circuit and initiates the female postmating response. We show that pCd-2 neurons also become silenced after mating due to the direct synaptic input from the mating status circuit. Thus, in mated females pCd-2 inhibition is attenuated, activating downstream Lgr3+ neurons and promoting sugar intake. Together, this circuit transforms the mated signal into a long-term hunger signal. Our results demonstrate that the mating circuit alters nutrient sensing centers to increase feeding in mated females, providing a mechanism to increase intake in anticipation of the energetic costs associated with reproduction.
    Keywords nutrition ; mating status ; feeding ; circuits ; insulin ; neuroendocrine pathways ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Subject code 590
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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