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  1. Book: Neurologie Fragen und Antworten

    Berlit, Peter / Krämer, Markus / Weber, Ralph

    über 1000 Fakten für die Facharztprüfung

    2012  

    Author's details Peter Berlit ; Markus Krämer ; Ralph Weber
    Keywords Neurologie
    Subject Klinische Neurologie
    Language German
    Size VI, 212 S.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017363430
    ISBN 978-3-642-29731-1 ; 3-642-29731-5 ; 9783642297328 ; 3642297323
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Transistorisch-ischämische Attacke/Hirninfarkt/Sekundärprophylaxe

    Weber, Ralph / Becker, Jana

    Neurologie up2date

    2022  Volume 05, Issue 03, Page(s) 200–207

    Language German
    Publishing date 2022-09-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2511-3658 ; 2511-3453
    ISSN (online) 2511-3658
    ISSN 2511-3453
    DOI 10.1055/a-1719-4851
    Database Thieme publisher's database

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  3. Article ; Online: Towards Post-Comparative Philosophy

    Nevad Kahteran / Ralph Weber

    Asian Studies, Vol 9, Iss

    2021  Volume 2

    Abstract: ...

    Abstract /
    Keywords comparative philosophy ; Chinese philosophy ; comparison ; methodology ; Social sciences and state - Asia (Asian studies only) ; H53
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher University of Ljubljana Press (Založba Univerze v Ljubljani)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Thesis: Belastungserleben von Pflegenden an einem Universitätsklinikum

    Weber, Ralph

    Streßsituation, Streßreaktion, Bewältigung und Arbeitszufriedenheit in Abhängigkeit von der Fachrichtung

    1996  

    Author's details vorgelegt von Ralph Weber
    Language German
    Size 164 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Diss., 1998
    HBZ-ID HT009329564
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Enhanced bone regeneration in rat calvarial defects through BMP2 release from engineered poly(ethylene glycol) hydrogels.

    Vallmajo-Martin, Queralt / Millan, Christopher / Müller, Ralph / Weber, Franz E / Ehrbar, Martin / Ghayor, Chafik

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4916

    Abstract: The clinical standard therapy for large bone defects, typically addressed through autograft or allograft donor tissue, faces significant limitations. Tissue engineering offers a promising alternative strategy for the regeneration of substantial bone ... ...

    Abstract The clinical standard therapy for large bone defects, typically addressed through autograft or allograft donor tissue, faces significant limitations. Tissue engineering offers a promising alternative strategy for the regeneration of substantial bone lesions. In this study, we harnessed poly(ethylene glycol) (PEG)-based hydrogels, optimizing critical parameters including stiffness, incorporation of arginine-glycine-aspartic acid (RGD) cell adhesion motifs, degradability, and the release of BMP2 to promote bone formation. In vitro we demonstrated that human bone marrow derived stromal cell (hBMSC) proliferation and spreading strongly correlates with hydrogel stiffness and adhesion to RGD peptide motifs. Moreover, the incorporation of the osteogenic growth factor BMP2 into the hydrogels enabled sustained release, effectively inducing bone regeneration in encapsulated progenitor cells. When used in vivo to treat calvarial defects in rats, we showed that hydrogels of low and intermediate stiffness optimally facilitated cell migration, proliferation, and differentiation promoting the efficient repair of bone defects. Our comprehensive in vitro and in vivo findings collectively suggest that the developed hydrogels hold significant promise for clinical translation for bone repair and regeneration by delivering sustained and controlled stimuli from active signaling molecules.
    MeSH term(s) Rats ; Humans ; Animals ; Bone Regeneration ; Biocompatible Materials/chemistry ; Osteogenesis ; Cell Differentiation ; Hydrogels/chemistry ; Polyethylene Glycols/chemistry ; Bone Morphogenetic Protein 2/pharmacology ; Bone Morphogenetic Protein 2/metabolism
    Chemical Substances Biocompatible Materials ; Hydrogels ; Polyethylene Glycols (3WJQ0SDW1A) ; BMP2 protein, human ; Bone Morphogenetic Protein 2
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55411-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Bewegliche Sachen

    Weber, Ralph

    (NomosLehrbuch ; Sachenrecht ; / Ralph Weber ; 1)

    2016  

    Author's details Ralph Weber
    Series title NomosLehrbuch
    Sachenrecht
    / Ralph Weber ; 1
    Language German
    Size 437 S., graph. Darst.
    Edition 4. Aufl.
    Publisher Nomos
    Publishing place Baden-Baden
    Document type Book
    Note Literaturangaben
    ISBN 3848706547 ; 9783845262826 ; 9783848706549 ; 3845262826
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book: Bewegliche Sachen

    Weber, Ralph

    (NomosLehrbuch ; Sachenrecht ; / Ralph Weber ; 1)

    2016  

    Author's details Ralph Weber
    Series title NomosLehrbuch
    Sachenrecht
    / Ralph Weber ; 1
    Keywords Sachenrecht
    Language German
    Size 437 S., graph. Darst.
    Edition 4. Aufl.
    Publisher Nomos
    Publishing place Baden-Baden
    Document type Book
    Note Literaturangaben
    ISBN 3848706547 ; 9783845262826 ; 9783848706549 ; 3845262826
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Grundstücksrecht

    Weber, Ralph

    (Nomos-Lehrbuch ; Sachenrecht ; / Ralph Weber ; 2)

    2015  

    Series title Nomos-Lehrbuch
    Sachenrecht
    / Ralph Weber ; 2
    Keywords Sachenrecht
    Language German
    Size 376 S.
    Edition 4. Aufl.
    Publisher Nomos-Verl.-Ges
    Publishing place Baden-Baden
    Document type Book
    Note Literaturverz. S. 23 - 24. - Literaturangaben
    ISBN 9783848706556 ; 3848706555
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book: Grundstücksrecht

    Weber, Ralph

    (Nomos-Lehrbuch ; Sachenrecht ; / Ralph Weber ; 2)

    2015  

    Series title Nomos-Lehrbuch
    Sachenrecht
    / Ralph Weber ; 2
    Language German
    Size 376 S.
    Edition 4. Aufl.
    Publisher Nomos-Verl.-Ges
    Publishing place Baden-Baden
    Document type Book
    Note Literaturverz. S. 23 - 24. - Literaturangaben
    ISBN 9783848706556 ; 3848706555
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article ; Online: Neurovaskuläre Manifestationen von COVID‑19.

    Veltkamp, Roland / Purrucker, Jan C / Weber, Ralph

    Der Nervenarzt

    2021  Volume 92, Issue 6, Page(s) 531–539

    Abstract: Even early at the beginning of the coronavirus disease 2019 (COVID‑19) pandemic, stroke was described as a manifestation or complication of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Current meta-analyses reported a ... ...

    Title translation Neurovascular manifestations of COVID‑19.
    Abstract Even early at the beginning of the coronavirus disease 2019 (COVID‑19) pandemic, stroke was described as a manifestation or complication of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Current meta-analyses reported a stroke rate of approximately 1.5%. Stroke in COVID‑19 positive patients occurs more frequently in severe courses of the infection and in older patients with cardiovascular comorbidities; however, young patients without cardiovascular risk factors are also not uncommonly affected. The mechanisms of stroke are predominantly embolic. The thrombi frequently occlude large intracranial vessels and in more than 20% affect multiple vascular territories, whereas infarctions due to small vessel disease are uncommon. The exact source of the embolism remains cryptogenic in more than 40% of patients. The mortality caused by the co-occurrence of a SARS-CoV‑2 infection and a stroke exceeds 15-30%. While acute stroke treatment was severely affected in some European regions, the rates of recanalization treatment in Germany largely remained stable during the first pandemic wave; however, 20-30% fewer patients with minor stroke and transient ischemic attacks (TIA) presented to hospitals during the first wave in spring 2020. The present narrative review summarizes the current evidence regarding the epidemiology and pathogenesis of stroke associated with COVID‑19 and describes the effect of the pandemic so far on the provision of acute stroke treatment.
    MeSH term(s) Aged ; Brain Ischemia ; COVID-19 ; Germany ; Humans ; Pandemics ; SARS-CoV-2 ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/therapy
    Language German
    Publishing date 2021-03-24
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 123291-5
    ISSN 1433-0407 ; 0028-2804
    ISSN (online) 1433-0407
    ISSN 0028-2804
    DOI 10.1007/s00115-021-01104-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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