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  1. Article: Chemical and biosynthetic potential of

    Zou, Ran / Li, Xin / Chen, Xiaochen / Guo, Yue-Wei / Xu, Baofu

    Beilstein journal of organic chemistry

    2024  Volume 20, Page(s) 597–606

    Abstract: ... ...

    Abstract Penicillium
    Language English
    Publishing date 2024-03-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2192461-2
    ISSN 1860-5397
    ISSN 1860-5397
    DOI 10.3762/bjoc.20.52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lattice Defects and Electronic Modulation of Flower-Like Zn

    Chen, Baofu / Wang, Yichao / Shen, Shijie / Zhong, Wenwu / Lu, Hongsheng / Pan, Yin

    Small methods

    2024  , Page(s) e2301598

    Abstract: Photocatalysis is an effective technique to remove antibiotic residues from aquatic environments. Typical metal sulfides like ... ...

    Abstract Photocatalysis is an effective technique to remove antibiotic residues from aquatic environments. Typical metal sulfides like Zn
    Language English
    Publishing date 2024-01-02
    Publishing country Germany
    Document type Journal Article
    ISSN 2366-9608
    ISSN (online) 2366-9608
    DOI 10.1002/smtd.202301598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Engineering a Cl

    Xiao, Lan / Yang, Qifan / Tan, Jingjing / Ma, Baofu / Chen, Deliang

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2023  Volume 29, Issue 70, Page(s) e202302543

    Abstract: Microbial ... ...

    Abstract Microbial Na
    MeSH term(s) Rhodopsin/chemistry ; Rhodopsin/metabolism ; Light ; Flavobacteriaceae/chemistry ; Flavobacteriaceae/metabolism ; Ion Transport ; Sodium/metabolism
    Chemical Substances Rhodopsin (9009-81-8) ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-10-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202302543
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  4. Article ; Online: Recent Advances for the Synthesis and Applications of 2-Dimensional Ternary Layered Materials

    Jing Peng / Zheng-jie Chen / Baofu Ding / Hui-Ming Cheng

    Research, Vol

    2023  Volume 6

    Abstract: Layered materials with unique structures and symmetries have attracted tremendous interest for constructing 2-dimensional (2D) structures. The weak interlayer interaction renders them to be readily isolated into various ultrathin nanosheets with exotic ... ...

    Abstract Layered materials with unique structures and symmetries have attracted tremendous interest for constructing 2-dimensional (2D) structures. The weak interlayer interaction renders them to be readily isolated into various ultrathin nanosheets with exotic properties and diverse applications. In order to enrich the library of 2D materials, extensive progress has been made in the field of ternary layered materials. Consequently, many brand-new materials are derived, which greatly extend the members of 2D realm. In this review, we emphasize the recent progress made in synthesis and exploration of ternary layered materials. We first classify them in terms of stoichiometric ratio and summarize their difference in interlayer interaction, which is of great importance to produce corresponding 2D materials. The compositional and structural characteristics of resultant 2D ternary materials are then discussed so as to realize desired structures and properties. As a new family of 2D materials, we overview the layer-dependent properties and related applications in the fields of electronics, optoelectronics, and energy storage and conversion. The review finally provides a perspective for this rapidly developing field.
    Keywords Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher American Association for the Advancement of Science
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Allosteric regulation in SARS-CoV-2 spike protein.

    Wei, Yong / Chen, Amy X / Lin, Yuewei / Wei, Tao / Qiao, Baofu

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 8, Page(s) 6582–6589

    Abstract: Allosteric regulation is common in protein-protein interactions and is thus promising in drug design. Previous experimental and simulation work supported the presence of allosteric regulation in the SARS-CoV-2 spike protein. Here the route of allosteric ... ...

    Abstract Allosteric regulation is common in protein-protein interactions and is thus promising in drug design. Previous experimental and simulation work supported the presence of allosteric regulation in the SARS-CoV-2 spike protein. Here the route of allosteric regulation in SARS-CoV-2 spike protein is examined by all-atom explicit solvent molecular dynamics simulations, contrastive machine learning, and the Ohm approach. It was found that peptide binding to the polybasic cleavage sites, especially the one at the first subunit of the trimeric spike protein, activates the fluctuation of the spike protein's backbone, which eventually propagates to the receptor-binding domain on the third subunit that binds to ACE2. Remarkably, the allosteric regulation routes starting from the polybasic cleavage sites share a high fraction (39-67%) of the critical amino acids with the routes starting from the nitrogen-terminal domains, suggesting the presence of an allosteric regulation network in the spike protein. Our study paves the way for the rational design of allosteric antibody inhibitors.
    MeSH term(s) Humans ; COVID-19 ; Spike Glycoprotein, Coronavirus/metabolism ; SARS-CoV-2/metabolism ; Binding Sites ; Protein Binding ; Allosteric Regulation ; Molecular Dynamics Simulation
    Chemical Substances spike protein, SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d4cp00106k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: K

    Xu, Jikang / Yang, Qifan / Ma, Baofu / Li, Longjie / Kong, Fei / Xiao, Lan / Chen, Deliang

    International journal of molecular sciences

    2023  Volume 24, Issue 19

    Abstract: Engineering light-controlled ... ...

    Abstract Engineering light-controlled K
    MeSH term(s) Sodium-Potassium-Exchanging ATPase/metabolism ; Rhodopsin/metabolism ; Ion Transport ; Biological Transport
    Chemical Substances Sodium-Potassium-Exchanging ATPase (EC 7.2.2.13) ; Rhodopsin (9009-81-8)
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241914414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Recent Advances for the Synthesis and Applications of 2-Dimensional Ternary Layered Materials.

    Peng, Jing / Chen, Zheng-Jie / Ding, Baofu / Cheng, Hui-Ming

    Research (Washington, D.C.)

    2023  Volume 6, Page(s) 40

    Abstract: Layered materials with unique structures and symmetries have attracted tremendous interest for constructing 2-dimensional (2D) structures. The weak interlayer interaction renders them to be readily isolated into various ultrathin nanosheets with exotic ... ...

    Abstract Layered materials with unique structures and symmetries have attracted tremendous interest for constructing 2-dimensional (2D) structures. The weak interlayer interaction renders them to be readily isolated into various ultrathin nanosheets with exotic properties and diverse applications. In order to enrich the library of 2D materials, extensive progress has been made in the field of ternary layered materials. Consequently, many brand-new materials are derived, which greatly extend the members of 2D realm. In this review, we emphasize the recent progress made in synthesis and exploration of ternary layered materials. We first classify them in terms of stoichiometric ratio and summarize their difference in interlayer interaction, which is of great importance to produce corresponding 2D materials. The compositional and structural characteristics of resultant 2D ternary materials are then discussed so as to realize desired structures and properties. As a new family of 2D materials, we overview the layer-dependent properties and related applications in the fields of electronics, optoelectronics, and energy storage and conversion. The review finally provides a perspective for this rapidly developing field.
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2639-5274
    ISSN (online) 2639-5274
    DOI 10.34133/research.0040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Base-Catalyzed One-Pot Synthesis of 2,3,6-Substituted Pyridines.

    Zhu, Baofu / He, Jiaming / Zou, Kai / Li, Anquan / Zhang, Chen / Zhao, Jiaji / Cao, Hua

    The Journal of organic chemistry

    2023  Volume 88, Issue 16, Page(s) 11450–11459

    Abstract: A three-component reaction catalyzed by base was established, which mainly consisted of ynals, isocyanates, amines and alcohols. This strategy provides a wide range of substrates and represents a simple process for the preparation of different pyridine ... ...

    Abstract A three-component reaction catalyzed by base was established, which mainly consisted of ynals, isocyanates, amines and alcohols. This strategy provides a wide range of substrates and represents a simple process for the preparation of different pyridine derivatives in good yields with high regioselectivities.
    Language English
    Publishing date 2023-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c00375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  9. Article ; Online: Tracking the effects of PLGA-based nanoparticles on protein expression in living cells through quantitative proteomics.

    Chen, Yuwan / Zhou, Wen / Liu, Jianhui / Li, Xinwei / Fu, Wenxin / Ma, Baofu / Liang, Zhen / Yang, Kaiguang / Zhang, Lihua / Zhang, Yukui

    Journal of materials chemistry. B

    2024  

    Abstract: Mass spectrometry (MS)-based proteomics can identify and quantify the differential abundance of expressed proteins in parallel, and bottom-up proteomic approaches are even approaching comprehensive coverage of the complex eukaryotic proteome. Protein- ... ...

    Abstract Mass spectrometry (MS)-based proteomics can identify and quantify the differential abundance of expressed proteins in parallel, and bottom-up proteomic approaches are even approaching comprehensive coverage of the complex eukaryotic proteome. Protein-nanoparticle (NP) interactions have been extensively studied owing to their importance in biological applications and nanotoxicology. However, the proteome-level effects of NPs on cells have received little attention, although changes in protein abundance can reflect the direct effects of nanocarriers on protein expression. Herein, we investigated the effect of PLGA-based NPs on protein expression in HepG2 cells using a label-free quantitative proteomics approach with data independent acquisition (DIA). The percentage of two-fold change in the protein expression of cells treated with PLGA-based NPs was less than 10.15% during a 6 hour observation period. Among the changed proteins, we found that dynamic proteins involved in cell division, localization, and transport are more likely to be more susceptible to PLGA-based NPs.
    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb01881d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Bioactive Cembranoids from the Coral

    Zeng, Zi-Rong / Chen, Jing / Wang, Hong / Zhang, Hai-Yan / Li, Jia / Xu, Baofu / Guo, Yue-Wei

    ACS omega

    2022  Volume 7, Issue 45, Page(s) 41678–41686

    Abstract: Eight new cembranoids (sarcophytembranoids A-H, ...

    Abstract Eight new cembranoids (sarcophytembranoids A-H,
    Language English
    Publishing date 2022-11-02
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c05687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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