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  1. Article ; Online: The authors reply.

    Farmakis, Dimitrios / Pipilis, Athanasios

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2014  Volume 55, Issue 1, Page(s) 779–780

    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/therapy ; Female ; Humans ; Male ; Registries/statistics & numerical data
    Language English
    Publishing date 2014-03-17
    Publishing country Netherlands
    Document type Comment ; Letter
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
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  2. Article ; Online: A perilous journey through the heart: Ventricular tachycardia caused by a foreign body.

    Sourlas, Nikolaos / Papavasileiou, Lida / Makrygiannis, Stamatis / Pipilis, Athanasios

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2016  

    Language English
    Publishing date 2016-09-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2016.09.005
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  3. Article ; Online: Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study.

    Kanakakis, Ioannis / Stafylas, Panagiotis / Tsigkas, Grigorios / Nikas, Dimitris / Synetos, Andreas / Avramidis, Dimitrios / Tsiafoutis, Ioannis / Dagre, Anna / Tzikas, Stergios / Latsios, Giorgos / Patsourakos, Nikos / Sanidas, Ilias / Skalidis, Emmanouil / Pipilis, Athanasios / Bamidis, Panagiotis / Davlouros, Periklis

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2022  Volume 67, Page(s) 1–8

    Abstract: Objective: Acute myocardial infarction (AMI) is one of the leading causes of death; however, updated data regarding clinical presentation and current management are missing in Greece. This study aimed to prospectively record the demographic and clinical ...

    Abstract Objective: Acute myocardial infarction (AMI) is one of the leading causes of death; however, updated data regarding clinical presentation and current management are missing in Greece. This study aimed to prospectively record the demographic and clinical characteristics of a representative sample of patients suffering from AMI, their management, and short-term outcomes.
    Methods: ILIAKTIS is a national, prospective, multicenter, noninterventional study conducted under the auspices of Hellenic Society of Cardiology (HCS) and the European Initiative Stent - Save a Life. From 1
    Results: In total, 1862 patients (mean age: 64.2 ± 13.2 yrs.; 77.2% males) with AMI were enrolled. More patients presented with NSTEMI (56.8%) than with STEMI (43.2%). Primary PCI (pPCI) was the preferable treatment option for STEMI patients in PCI-hospitals (76.9% vs. 39.9% for non-PCI, p < .001) and thrombolysis in non-PCI-hospitals (47.3% vs. 17.9% for PCI-hospitals, p < .001). The mean length of hospital stay was 5.6 days. In-hospital mortality was less likely in NSTEMI compared to that in STEMI patients (aOR = 0.30; 95% CI 0.18 to 0.49). Patients initially admitted in non-PCI-hospitals showed increased risk for in-hospital (aOR = 2.29; 95% CI 1.20 to 4.42) and 30-day mortality (aOR = 1.88; 95% CI 1.20 to 2.96).
    Conclusion: This study shows that the proportion of STEMI and NSTEMI patients managed interventionally has significantly increased, resulting in better clinical outcomes compared to previous Greek surveys.
    MeSH term(s) Adult ; Aged ; Female ; Greece/epidemiology ; Humans ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Myocardial Infarction/therapy ; Non-ST Elevated Myocardial Infarction/epidemiology ; Non-ST Elevated Myocardial Infarction/etiology ; Non-ST Elevated Myocardial Infarction/therapy ; Percutaneous Coronary Intervention/adverse effects ; Prospective Studies ; Registries ; Reperfusion ; ST Elevation Myocardial Infarction/epidemiology ; ST Elevation Myocardial Infarction/therapy ; Time Factors
    Language English
    Publishing date 2022-03-17
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2022.03.003
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  4. Article ; Online: Anticoagulation therapy in elderly patients with atrial fibrillation: results from the Registry of Atrial Fibrillation To Investigate the Implementation of New Guidelines (RAFTING).

    Pipilis, Athanasios / Farmakis, Dimitrios / Kaliambakos, Sotirios / Goudevenos, John / Lekakis, John

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2017  Volume 18, Issue 7, Page(s) 545–549

    Abstract: Background: Patients with atrial fibrillation aged 75 years or older have a CHA2DS2VASc score that dictates oral anticoagulants. We recorded physicians' anticoagulation attitudes in elderly patients with atrial fibrillation and assessed the impact of ... ...

    Abstract Background: Patients with atrial fibrillation aged 75 years or older have a CHA2DS2VASc score that dictates oral anticoagulants. We recorded physicians' anticoagulation attitudes in elderly patients with atrial fibrillation and assessed the impact of stroke and bleeding risk.
    Methods: Atrial Fibrillation To Investigate the Implementation of New Guidelines , a countrywide prospective registry performed in Greece during 2010, a period when only vitamin-K antagonists (VKA) were available, enrolled 1127 patients with atrial fibrillation diagnosis during Emergency Departments visit in 31 representative hospitals; 807 patients had known atrial fibrillation and of those, 342 aged 75 years or older. We recorded preadmission anticoagulation treatment and associated it with clinical characteristics and stroke/bleeding risk.
    Results: Patients on VKA (n = 207; 61%) were younger (81 ± 4 vs. 83 ± 5; P < 0.001) but no other significant differences were noticed, including mean CHA2DS2VASc (high: 2-4, very high: >4) or modified HASBLED (low: 0-2, high: >2) scores. VKA were prescribed in 65% of patients with very high CHA2DS2VASc score as compared with 55% of those with high score (P = 0.065). VKA were used equally in low or high-modified HASBLED score (61% vs. 59%; P = 0.78). The interaction between CHA2DS2VASc and HASBLED was significant (P < 0.001) in patients on VKA; in patients with low HASBLED, VKA use was similar in high versus very high CHA2DS2VASc score (58 vs. 64%), whereas in patients with high HASBLED, VKA use tended to be higher in very high versus high CHA2DS2VASc score (66 vs. 43%).
    Conclusion: In this countrywide atrial fibrillation registry, 61% of elderly patients received VKA, a decision driven mainly by stroke risk. VKA use was not higher in patients with low bleeding risk.
    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000000355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: Practical Considerations on the Choice of Agent and Dosing.

    Farmakis, Dimitrios / Davlouros, Periklis / Giamouzis, Gregory / Giannakoulas, George / Pipilis, Athanasios / Tsivgoulis, Georgios / Parissis, John

    Cardiology

    2018  Volume 140, Issue 2, Page(s) 126–132

    Abstract: Direct or new oral anticoagulants (NOACs), including the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban, have recently revolutionized the field of antithrombotic therapy for stroke and ... ...

    Abstract Direct or new oral anticoagulants (NOACs), including the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban, have recently revolutionized the field of antithrombotic therapy for stroke and systemic embolism prevention in nonvalvular atrial fibrillation (NVAF). Randomized controlled trials have shown that these agents have at least comparable efficacy with vitamin K antagonists along with superior safety, at least in what concerns intracranial hemorrhage. As a result, NOACs are indicated as first-line anticoagulation therapy for NVAF patients with at least one risk factor for stroke or systemic embolism. The rapid introduction, however, of NOACs in a field dominated for decades by vitamin antagonists and the variety of agents and dosing schemes may create difficulties in decision making. In the present article, we attempt to determine a practical approach to the choice of agent and dose in different clinical scenarios by considering not only the results of seminal randomized trials and post hoc analyses but also data from real-world patient populations as well as the recently available possibility of rapid NOAC reversal.
    MeSH term(s) Administration, Oral ; Aged ; Aged, 80 and over ; Anticoagulants/administration & dosage ; Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Decision Making ; Embolism/complications ; Embolism/drug therapy ; Embolism/prevention & control ; Female ; Humans ; Male ; Randomized Controlled Trials as Topic ; Risk Factors ; Stroke/complications ; Stroke/drug therapy ; Stroke/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2018-07-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000489922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Electronic medical registry of acute coronary syndromes in Greece. (ILIAKTIS study): Rationale and study design.

    Kanakakis, Ioannis / Stafylas, Panagiotis / Avramidis, Dimitrios / Dagre, Anna / Latsios, George / Nikas, Dimitris / Patsourakos, Nikos / Pipilis, Athanasios / Sanidas, Ilias / Skalidis, Emmanouil / Synetos, Andreas / Tziakas, Dimitrios / Tzikas, Stergios / Tsiafoutis, Ioannis / Tsigkas, Grigoris / Bamidis, Panagiotis

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2020  Volume 62, Issue 3, Page(s) 244–247

    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/epidemiology ; Acute Coronary Syndrome/therapy ; Electronics ; Greece/epidemiology ; Humans ; Registries ; Research Design
    Language English
    Publishing date 2020-07-14
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2020.06.011
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  7. Article ; Online: Novel oral anticoagulants in atrial fibrillation: will the benefit outweigh the cost?

    Goudevenos, John / Pipilis, Athanasios / Vardas, Panos

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2012  Volume 53, Issue 2, Page(s) 137–141

    MeSH term(s) Administration, Oral ; Anticoagulants/administration & dosage ; Anticoagulants/economics ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/economics ; Drug Costs ; Humans ; Stroke/etiology ; Stroke/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2012-03-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
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  8. Article: Superior vena cava syndrome: 1757-2007.

    Danias, Peter G / Pipilis, Athanasios G

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2008  Volume 48, Issue 6, Page(s) 366–367

    MeSH term(s) Autopsy/history ; Autopsy/methods ; England ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Magnetic Resonance Imaging/history ; Magnetic Resonance Imaging/methods ; Scotland ; Superior Vena Cava Syndrome/diagnosis ; Superior Vena Cava Syndrome/history
    Language English
    Publishing date 2008-01-11
    Publishing country Netherlands
    Document type Historical Article ; Journal Article
    ZDB-ID 2215027-4
    ISSN 1109-9666
    ISSN 1109-9666
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  9. Article: Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: Practical Considerations on the Choice of Agent and Dosing

    Farmakis, Dimitrios / Davlouros, Periklis / Giamouzis, Gregory / Giannakoulas, George / Pipilis, Athanasios / Tsivgoulis, Georgios / Parissis, John

    Cardiology

    2018  Volume 140, Issue 2, Page(s) 126–132

    Abstract: Direct or new oral anticoagulants (NOACs), including the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban, have recently revolutionized the field of antithrombotic therapy for stroke and ... ...

    Institution Department of Cardiology, Heart Failure Unit, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece
    Department of Cardiology, Patras University Hospital, Patras, Greece
    Department of Cardiology, Larissa University Hospital, Larissa, Greece
    First<bold></bold> Department of Cardiology, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    First Department of Cardiology, Hygeia Hospital, Athens, Greece
    Second Department of Neurology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece
    Abstract Direct or new oral anticoagulants (NOACs), including the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban, have recently revolutionized the field of antithrombotic therapy for stroke and systemic embolism prevention in nonvalvular atrial fibrillation (NVAF). Randomized controlled trials have shown that these agents have at least comparable efficacy with vitamin K antagonists along with superior safety, at least in what concerns intracranial hemorrhage. As a result, NOACs are indicated as first-line anticoagulation therapy for NVAF patients with at least one risk factor for stroke or systemic embolism. The rapid introduction, however, of NOACs in a field dominated for decades by vitamin antagonists and the variety of agents and dosing schemes may create difficulties in decision making. In the present article, we attempt to determine a practical approach to the choice of agent and dose in different clinical scenarios by considering not only the results of seminal randomized trials and post hoc analyses but also data from real-world patient populations as well as the recently available possibility of rapid NOAC reversal.
    Keywords Atrial fibrillation ; New oral anticoagulants ; Dabigatran ; Rivaroxaban ; Apixaban ; Edoxaban
    Language English
    Publishing date 2018-07-05
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Review
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000489922
    Database Karger publisher's database

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  10. Article ; Online: Triple antithrombotic therapy with aspirin, a thienopyridine derivative plus oral anticoagulation in patients with atrial fibrillation undergoing coronary stenting.

    Pipilis, Athanasios / Lazaros, George / Tsakonas, Georgios / Stefanadis, Christodoulos

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2010  Volume 51, Issue 4, Page(s) 330–337

    MeSH term(s) Acute Coronary Syndrome/complications ; Acute Coronary Syndrome/surgery ; Administration, Oral ; Angioplasty, Balloon, Coronary ; Anticoagulants/administration & dosage ; Anticoagulants/adverse effects ; Aspirin/administration & dosage ; Aspirin/adverse effects ; Atrial Fibrillation/complications ; Coronary Vessels ; Drug Therapy, Combination ; Hemorrhage/chemically induced ; Humans ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Pyridines/administration & dosage ; Pyridines/adverse effects ; Risk Factors ; Stents/adverse effects ; Thrombosis/etiology ; Thrombosis/prevention & control ; Ticlopidine/administration & dosage ; Ticlopidine/adverse effects ; Ticlopidine/analogs & derivatives ; Warfarin/administration & dosage ; Warfarin/adverse effects
    Chemical Substances Anticoagulants ; Platelet Aggregation Inhibitors ; Pyridines ; thienopyridine ; Warfarin (5Q7ZVV76EI) ; clopidogrel (A74586SNO7) ; Ticlopidine (OM90ZUW7M1) ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2010-09-30
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
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