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Article: Semiochemicals from Domestic Cat Urine and Feces Reduce Use of Scratching Surfaces.

Zhang, Lingna / Aviles-Rosa, Edgar O / Bian, Zhaowei / Surowiec, Kaz / McGlone, John J

Animals : an open access journal from MDPI

2024 Volume 14, Issue 3

Abstract: Scratching is a natural behavior in cats but can cause damage to household furnishings. In this work, we sought to identify potential semiochemicals in the urine and feces of domestic cats that may modify cat scratching behavior. Sex differences among ... ...

Abstract	Scratching is a natural behavior in cats but can cause damage to household furnishings. In this work, we sought to identify potential semiochemicals in the urine and feces of domestic cats that may modify cat scratching behavior. Sex differences among adult, intact cats were examined for volatile molecules in their urine (
Language	English
Publishing date	2024-02-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani14030520
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Article ; Online: Linking African herbivore community enamel isotopes and environments: challenges, opportunities, and paleoecological implications.

Norwood, Alexandra L / Wang, Bian / Kingston, John D

Oecologia

2024 Volume 204, Issue 3, Page(s) 467–489

Abstract: Paleoenvironmental reconstructions of fossil sites based on isotopic analyses of enamel typically rely on data from multiple herbivore taxa, with the assumption that this dietary spectrum represents the community's isotopic range and provides insights ... ...

Abstract	Paleoenvironmental reconstructions of fossil sites based on isotopic analyses of enamel typically rely on data from multiple herbivore taxa, with the assumption that this dietary spectrum represents the community's isotopic range and provides insights into local or regional vegetation patterns. However, it remains unclear how representative the sampled taxa are of the broader herbivore community and how well these data correspond to specific ecosystems. Verifying these underlying assumptions is essential to refining the utility of enamel isotopic values for paleoenvironmental reconstructions. This study explores potential links between modern herbivore community carbon isotopic enamel spectra, biome types, and climate in sub-Saharan Africa. This region is one of the most comprehensively isotopically sampled areas globally and is of particular relevance to hominin evolution. Our extensive data compilation reveals that published enamel isotopic data from sub-Saharan Africa typically sample only a small percentage of the taxa documented at most localities and that some biome types (e.g., subtropical savannas) are dramatically overrepresented relative to others (e.g., forests) in these modern data sets. Multiple statistical analyses, including linear models and cluster analyses, revealed weak relationships of associated mammalian herbivore enamel isotopic values, biome type, and climate parameters. These results confound any simple assumptions about how community isotopic profiles map onto specific environments, highlighting the need for more precise strategic approaches in extending isotopic frameworks into the past for paleoecological reconstructions. Developing more refined modern analogs will ultimately allow us to more accurately characterize the isotopic spectra of paleo-communities and link isotopic dietary signatures to specific ecosystems.
MeSH term(s)	Animals ; Carbon Isotopes/analysis ; Ecosystem ; Fossils ; Herbivory ; Hominidae ; Mammals
Chemical Substances	Carbon Isotopes
Language	English
Publishing date	2024-03-22
Publishing country	Germany
Document type	Journal Article
ZDB-ID	123369-5
ISSN	1432-1939 ; 0029-8549
ISSN (online)	1432-1939
ISSN	0029-8549
DOI	10.1007/s00442-024-05532-z
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Article ; Online: Deep Learning-Based construction of a Drug-Like compound database and its application in virtual screening of HsDHODH inhibitors.

Xia, Wei / Xiao, Jin / Bian, Hengwei / Zhang, Jiajun / Zhang, John Z H / Zhang, Haiping

Methods (San Diego, Calif.)

2024 Volume 225, Page(s) 44–51

Abstract: The process of virtual screening relies heavily on the databases, but it is disadvantageous to conduct virtual screening based on commercial databases with patent-protected compounds, high compound toxicity and side effects. Therefore, this paper ... ...

Abstract	The process of virtual screening relies heavily on the databases, but it is disadvantageous to conduct virtual screening based on commercial databases with patent-protected compounds, high compound toxicity and side effects. Therefore, this paper utilizes generative recurrent neural networks (RNN) containing long short-term memory (LSTM) cells to learn the properties of drug compounds in the DrugBank, aiming to obtain a new and virtual screening compounds database with drug-like properties. Ultimately, a compounds database consisting of 26,316 compounds is obtained by this method. To evaluate the potential of this compounds database, a series of tests are performed, including chemical space, ADME properties, compound fragmentation, and synthesizability analysis. As a result, it is proved that the database is equipped with good drug-like properties and a relatively new backbone, its potential in virtual screening is further tested. Finally, a series of seedling compounds with completely new backbones are obtained through docking and binding free energy calculations.
MeSH term(s)	Deep Learning ; Molecular Docking Simulation/methods ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Drug Evaluation, Preclinical/methods ; Humans ; Databases, Pharmaceutical ; Neural Networks, Computer ; Databases, Chemical
Chemical Substances	Enzyme Inhibitors
Language	English
Publishing date	2024-03-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1066584-5
ISSN	1095-9130 ; 1046-2023
ISSN (online)	1095-9130
ISSN	1046-2023
DOI	10.1016/j.ymeth.2024.03.008
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Article ; Online: Overuse of colorectal cancer screening services in the United States and its implications.

Bian, John

Chinese journal of cancer

2016 Volume 35, Issue 1, Page(s) 88

Abstract: As a standard way for prevention and early detection of colorectal cancer (CRC), colonoscopy has been used for CRC screening in the United States for more than one decade. An article entitled "Assessing Colorectal Cancer Screening Adherence of Medicare ... ...

Abstract	As a standard way for prevention and early detection of colorectal cancer (CRC), colonoscopy has been used for CRC screening in the United States for more than one decade. An article entitled "Assessing Colorectal Cancer Screening Adherence of Medicare Fee-For-Service Beneficiaries Age 76 to 95 Years" recently published at the Journal of Oncology Practice reports the trends in overuse of CRC screening services among average-risk elderly populations at the age of 76-95 years. Several reasons for overusing colonoscopy have been postulated, and some strategies for reducing overuse of CRC screening services have also been proposed.
MeSH term(s)	Colonoscopy/standards ; Colonoscopy/utilization ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/epidemiology ; Early Detection of Cancer/standards ; Early Detection of Cancer/utilization ; Humans ; Population Surveillance ; Preventive Health Services/standards ; Preventive Health Services/utilization ; United States ; Unnecessary Procedures/standards ; Unnecessary Procedures/utilization
Language	English
Publishing date	2016-09-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1045160-2
ISSN	1944-446X ; 1000-467X
ISSN (online)	1944-446X
ISSN	1000-467X
DOI	10.1186/s40880-016-0148-5
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Article ; Online: The 3D mutational constraint on amino acid sites in the human proteome

Bian Li / Dan M. Roden / John A. Capra

Nature Communications, Vol 13, Iss 1, Pp 1-

2022 Volume 15

Abstract: Here, Li et al. integrate population genetic and protein structural perspectives to map the landscape of 3D constraint on 80% of human proteins. They show that 3D mutational constraint is pervasive and strongly associated with functional relevance. ...

Abstract	Here, Li et al. integrate population genetic and protein structural perspectives to map the landscape of 3D constraint on 80% of human proteins. They show that 3D mutational constraint is pervasive and strongly associated with functional relevance.
Keywords	Science ; Q
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Applications of waste polyethylene terephthalate (PET) based nanostructured materials: A review.

Bian, Xueyan / Xia, Gang / Xin, John H / Jiang, Shouxiang / Ma, Kaikai

Chemosphere

2023 Volume 350, Page(s) 141076

Abstract: While polyethylene terephthalate (PET) has enjoyed widespread use, a large volume of plastic waste has also been produced as a result, which is detrimental to the environment. Traditional treatment of plastic waste, such as landfilling and incinerating ... ...

Abstract	While polyethylene terephthalate (PET) has enjoyed widespread use, a large volume of plastic waste has also been produced as a result, which is detrimental to the environment. Traditional treatment of plastic waste, such as landfilling and incinerating waste, causes environmental pollution and poses risks to public health. Recycling PET waste into useful chemicals or upcycling the waste into high value-added materials can be remedies. This review first provides a brief introduction of the synthesis, structure, properties, and applications of virgin PET. Then the conversion process of waste PET into high value-added materials for different applications are introduced. The conversion mechanisms (including degradation, recycling and upcycling) are detailed. The advanced applications of these upgraded materials in energy storage devices (supercapacitors, lithium-ion batteries, and microbial fuel cells), and for water treatment (to remove dyes, heavy metals, and antibiotics), environmental remediation (for air filtration, CO
MeSH term(s)	Polyethylene Terephthalates/chemistry ; Carbon Dioxide ; Recycling ; Environmental Restoration and Remediation ; Nanostructures ; Plastics/chemistry
Chemical Substances	Polyethylene Terephthalates ; Carbon Dioxide (142M471B3J) ; Plastics
Language	English
Publishing date	2023-12-31
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.141076
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Article ; Online: Recent advances in cotton fabric-based photocatalytic composites for the degradation of organic contaminants.

Xia, Gang / Lam, Yintung / Fan, Suju / Bian, Xueyan / Qi, Peng / Qiao, Zhiwei / Ma, Kaikai / Xin, John H

Carbohydrate polymers

2024 Volume 332, Page(s) 121872

Abstract: Cotton is one of the oldest and most widely used natural fibers in the world. It enables a wide range of applications due to its excellent moisture absorption, thermal insulation, heat resistance, and durability. Benefiting from current developments in ... ...

Abstract	Cotton is one of the oldest and most widely used natural fibers in the world. It enables a wide range of applications due to its excellent moisture absorption, thermal insulation, heat resistance, and durability. Benefiting from current developments in textile technology and materials science, people are constantly seeking more comfortable, more beautiful and more versatile cotton fabrics. As the second skin of body, clothing not only provides the basic needs of wear but also increases the protection of body against different environmental stimuli. In this article, a comprehensive review is proposed regarding research activities of systematically summarise the development and research of cotton fabric-based photocatalytic composites for the degradation of organic contaminants in the area of self-cleaning, degradation of gaseous contaminants, pathogenic bacteria or viruses, and chemical warfare agents. Specifically, we begin with a brief exposition of the background and significance of cotton fabric-based photocatalytic composites. Next, a systematical review on cotton fabric-based photocatalytic composites is provided according to their mechanisms and advanced applications. Finally, a simple summary and analysis concludes the current limitations and future directions in these composites for the degradation of organic contaminants.
Language	English
Publishing date	2024-02-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1501516-6
ISSN	1879-1344 ; 0144-8617
ISSN (online)	1879-1344
ISSN	0144-8617
DOI	10.1016/j.carbpol.2024.121872
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Article: Proteomics analysis reveals differential acclimation of coastal and oceanic

Schiksnis, Cara / Xu, Min / Saito, Mak A / McIlvin, Matthew / Moran, Dawn / Bian, Xiaopeng / John, Seth G / Zheng, Qiang / Yang, Nina / Fu, Feixue / Hutchins, David A

Frontiers in microbiology

2024 Volume 15, Page(s) 1323499

Abstract: In many oceanic regions, anthropogenic warming will coincide with iron (Fe) limitation. Interactive effects between warming and Fe limitation on phytoplankton physiology and biochemical function are likely, as temperature and Fe availability affect many ... ...

Abstract	In many oceanic regions, anthropogenic warming will coincide with iron (Fe) limitation. Interactive effects between warming and Fe limitation on phytoplankton physiology and biochemical function are likely, as temperature and Fe availability affect many of the same essential cellular pathways. However, we lack a clear understanding of how globally significant phytoplankton such as the picocyanobacteria
Language	English
Publishing date	2024-02-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2024.1323499
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Article ; Online: Population-based screening of hepatitis C virus in the United States.

Bian, John / Schreiner, Andrew D

Current opinion in gastroenterology

2019 Volume 35, Issue 3, Page(s) 177–182

Abstract: Purpose of review: This review summarized the recent evidence on the performance of population-based hepatitis C virus (HCV) screening, published and indexed to PubMed, in the Unite States during the 2-year window from 1 January 2017 to 31 December 2018. ...

Abstract	Purpose of review: This review summarized the recent evidence on the performance of population-based hepatitis C virus (HCV) screening, published and indexed to PubMed, in the Unite States during the 2-year window from 1 January 2017 to 31 December 2018. Recent findings: A majority of the selected articles in this review focused on the birth cohort 1945-1965 because of the HCV screening recommendations released after August 2012. However, the articles for the high-risk population applied to all ages because the recommendations for this specific population have remained largely unchanged since 1998. The reported rates of HCV screening varied substantially not only across the three different populations (i.e. general, underserved, and high-risk) but also within each population. Summary: More vigilant monitoring of HCV screening performance of younger birth cohorts is needed as these individuals have been experiencing a higher incidence of HCV infection than those in the birth cohort 1945-1965. In addition, to meet the goal of eliminating HCV infection as a US public health problem by 2030, significant improvement in more accurately and comprehensively reporting the trends in population-based HCV screening across different populations is warranted in the future.
MeSH term(s)	Centers for Disease Control and Prevention, U.S. ; Hepatitis C/diagnosis ; Hepatitis C/epidemiology ; Hepatitis C Antibodies/blood ; Humans ; Mass Screening/standards ; Mass Screening/statistics & numerical data ; Practice Guidelines as Topic ; RNA, Viral/blood ; Risk Factors ; United States/epidemiology ; United States Department of Veterans Affairs
Chemical Substances	Hepatitis C Antibodies ; RNA, Viral
Language	English
Publishing date	2019-02-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	632571-3
ISSN	1531-7056 ; 0267-1379
ISSN (online)	1531-7056
ISSN	0267-1379
DOI	10.1097/MOG.0000000000000520
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Article ; Online: The 3D mutational constraint on amino acid sites in the human proteome.

Li, Bian / Roden, Dan M / Capra, John A

Nature communications

2022 Volume 13, Issue 1, Page(s) 3273

Abstract: Quantification of the tolerance of protein sites to genetic variation has become a cornerstone of variant interpretation. We hypothesize that the constraint on missense variation at individual amino acid sites is largely shaped by direct interactions ... ...

Abstract	Quantification of the tolerance of protein sites to genetic variation has become a cornerstone of variant interpretation. We hypothesize that the constraint on missense variation at individual amino acid sites is largely shaped by direct interactions with 3D neighboring sites. To quantify this constraint, we introduce a framework called COntact Set MISsense tolerance (or COSMIS) and comprehensively map the landscape of 3D mutational constraint on 6.1 million amino acid sites covering 16,533 human proteins. We show that 3D mutational constraint is pervasive and that the level of constraint is strongly associated with disease relevance both at the site and the protein level. We demonstrate that COSMIS performs significantly better at variant interpretation tasks than other population-based constraint metrics while also providing structural insight into the functional roles of constrained sites. We anticipate that COSMIS will facilitate the interpretation of protein-coding variation in evolution and prioritization of sites for mechanistic investigation.
MeSH term(s)	Amino Acids/genetics ; Humans ; Mutation ; Proteome/genetics
Chemical Substances	Amino Acids ; Proteome
Language	English
Publishing date	2022-06-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-022-30936-x
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