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  1. Article ; Online: A retrospective cohort study: is COVID-19 BNT162b2 mRNA vaccination a trigger factor for cluster headache?

    Aşkın Turan, Suna / Aydın, Şenay

    Acta neurologica Belgica

    2024  

    Abstract: OBJECTıVE: Cluster headache (CH) is a coronavirus 2019 (COVID-19) vaccination-related adverse event. There are a few case reports of relapses or de novo cluster episodes following the vaccine. The disease's pathophysiology is still not clear. The most ... ...

    Abstract OBJECTıVE: Cluster headache (CH) is a coronavirus 2019 (COVID-19) vaccination-related adverse event. There are a few case reports of relapses or de novo cluster episodes following the vaccine. The disease's pathophysiology is still not clear. The most widely accepted mechanism is activation of the trigeminocervical complex (TCC). However, the correlation between vaccination and CH is unexplainable. Its goal is to compare the CH bouts of patients before and after the vaccine.
    Methods: Patients with a history of CH and who had never experienced COVID-19 illness during the pandemic were included in this retrospective cohort analysis. The semi-structured survey was administered face to face to 24 CH patients (16 male). The headache features before and after vaccination were detailed in this survey.
    Results: 18 patients got vaccinated twice, and 6 of them had no vaccination. After the first vaccination, 83.3% of them had CH bout; after the second vaccination, 72.2% of them had CH bout. We divided headache episodes into three groups: (1) before vaccination, (2) after the first vaccination, and (3) after the second vaccination. The third group had a higher pain intensity (9.30 ± 0.630, p = 0.047) and remitting longer (20.00 ± 5.40 days, p = 0.019) than the other groups. The management of the 53.3% bouts after vaccinations was less effective than the usual episodes.
    Conclusion: Most ECH patients experienced new bouts more intense and longer duration after vaccinations than their previous bouts, the mechanism, and pathogenesis of the bouts are the subject of future research. The new studies can be a light for understanding the CH pathophysiology more deeply.
    Language English
    Publishing date 2024-04-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-024-02536-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Subfatin, Asprosin, Alamandine and Maresin-1 Inflammation Molecules in Cardiopulmonary Bypass.

    Hanbeyoglu, Onur / Aydin, Suna

    Journal of inflammation research

    2023  Volume 16, Page(s) 3469–3477

    Abstract: Purpose: Cardiopulmonary bypass (CPB) is a nonphysiological procedure in which inflammatory reactions and oxidative stress are induced, hormones and hemodynamic parameters are affected, and circulation is maintained outside the body. This study aimed to ...

    Abstract Purpose: Cardiopulmonary bypass (CPB) is a nonphysiological procedure in which inflammatory reactions and oxidative stress are induced, hormones and hemodynamic parameters are affected, and circulation is maintained outside the body. This study aimed to examine the effects of CPB on blood subfatin (SUB), asprossin (ASP), alamandine (ALA) and maresin-1 (MaR-1) levels.
    Materials and methods: Controls and patients who underwent open-heart surgery with CPB and whose age and body mass indices were compatible with each other were included in the study. Venous blood samples were collected from CPB patients (n =19) before anesthesia induction (T1), before CPB (T2), 5 min before cross-clamp removal (T3), 5 min after cross-clamp removal (T4), when taken to the intensive care unit (T5), postoperative 24th hour (T6) and 72nd hour (T7) postoperatively. Venous blood was collected from the healthy controls (n =19). The amounts of SUB, ASP, ALA, and MaR-1 in the blood samples were measured using an Enzyme-Linked Immunosorbent Assay (ELISA).
    Results: The amounts of SUB and MaR-1 in the control group were significantly higher than those in CPB patients, while these parameters in T1-T3 blood gradually decreased in CPB patients (
    Conclusion: These hormonal changes in the organism due to CPB demonstrate that "hormonal metabolic adaptation" mechanisms may be activated to eliminate the negative consequences of surgery. According to these data, SUB, MaR-1, anti-alamandine, and anti-asprosin could be used in CPB surgeries may come to the fore in the future to increase the safety of CPB surgeries.
    Language English
    Publishing date 2023-08-16
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494878-0
    ISSN 1178-7031
    ISSN 1178-7031
    DOI 10.2147/JIR.S422998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Distribution of Scabies Infestations in Stray Dogs in Bursa Province.

    Saygın, Betül / Girişgin, Ahmet Onur / Zengin, Suna Aslı / Aydın, Levent

    Turkiye parazitolojii dergisi

    2024  Volume 48, Issue 1, Page(s) 45–50

    Abstract: Objective: Scabies infestation is a major parasitic disease affecting both human and animal health worldwide. This study aimed to determine the distribution of scabies infestation in stray dogs in Bursa province.: Methods: The study material was ... ...

    Title translation Bursa Yöresi Sokak Köpeklerinde Uyuz Enfestasyonlarının Yaygınlığı.
    Abstract Objective: Scabies infestation is a major parasitic disease affecting both human and animal health worldwide. This study aimed to determine the distribution of scabies infestation in stray dogs in Bursa province.
    Methods: The study material was obtained from stray dogs suspected of mange kept in a municipal shelter in Bursa between June 2020 and February 2022. Samples from stray dogs were examined in a laboratory, and dogs with scabies were determined.
    Results: During the study, samples were collected from 205 (115 males, 90 females) scabies-suspected stray dogs, 58 (28.29%) of which had scabies.
    Conclusion: This study identified scabies agents and their prevalence rate in stray dogs of Bursa province, Türkiye.
    MeSH term(s) Humans ; Animals ; Dogs ; Female ; Male ; Scabies/epidemiology ; Scabies/veterinary ; Sarcoptes scabiei ; Laboratories ; Seasons
    Language English
    Publishing date 2024-03-07
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2651106-X
    ISSN 2146-3077 ; 2146-3077
    ISSN (online) 2146-3077
    ISSN 2146-3077
    DOI 10.4274/tpd.galenos.2023.79664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Can Pre-analytical Mistake Bearing Irisin Concentrations Be an Indicator of Coronary Artery Disease?

    Aydin, Suna

    Korean circulation journal

    2018  Volume 48, Issue 1, Page(s) 94–95

    Language English
    Publishing date 2018-01-10
    Publishing country Korea (South)
    Document type Letter
    ZDB-ID 2557464-4
    ISSN 1738-5520
    ISSN 1738-5520
    DOI 10.4070/kcj.2017.0060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of Cardiopulmonary Bypass Operation on Circulating Levels of Adropin, Elabela, and Nitric Oxide Depending on the Time Intervals

    Suna Aydın

    Koşuyolu Heart Journal, Vol 21, Iss 3, Pp 204-

    2018  Volume 210

    Abstract: Introduction: Elabela and adropin (nitric oxide-mediated effects) are two new hormones that are synthesized in the heart and discovered in the last decade, which play a role in vascular system homeostasis. Therefore, the main aim of this study was to ... ...

    Abstract Introduction: Elabela and adropin (nitric oxide-mediated effects) are two new hormones that are synthesized in the heart and discovered in the last decade, which play a role in vascular system homeostasis. Therefore, the main aim of this study was to examine the changes of adropin, elabela, and nitric oxide in blood samples taken at various time intervals during a coronary artery bypass graft using cardiopulmonary bypass. Patients and Methods: This study included 20 healthy individuals and 15 patients undergoing cardiopulmonary bypass surgery. Blood samples were taken from patients who had cardiopulmonary bypass surgery before anesthesia induction (T1), before bypass (T2), before removing the cross-clamp (T3), at the intensive care unit (T4), and at postoperative 24 (T5), 48 (T6), and 72 hours (T7). A blood sample was taken once from the healthy volunteer control group. Blood adropin, elabela, and nitric oxide quantities were measured by ELISA. Results: When the control adropin and nitric oxide blood values were compared with the adropin and nitric oxide blood values obtained at T1, adropin and nitric oxide levels in the blood collected during the T1 time interval were significantly lower. Elabela and lactate levels in the blood at the T1 time interval were significantly higher. In the blood samples taken at postoperative 24 (T5), 48 (T6), and 72 hours (T7), both blood elabela and blood lactate began to decrease significantly. Conclusion: Significant changes in the amount of these molecules in blood samples taken at various time intervals during cardiopulmonary bypass operation are promising in the monitoring of coronary artery bypass surgery.
    Keywords Adropin ; elabela ; nitric oxide ; coronary artery bypass ; graft ; Medicine ; R ; Diseases of the circulatory (Cardiovascular) system ; RC666-701
    Subject code 610
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Bilimsel Tip Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Can vitamin K synthesis altered by dysbiosis of microbiota be blamed in the etiopathogenesis of venous thrombosis?

    Aydin, Suna

    Bioscience of microbiota, food and health

    2017  Volume 36, Issue 3, Page(s) 73–74

    Language English
    Publishing date 2017-04-21
    Publishing country Japan
    Document type Journal Article
    ISSN 2186-6953
    ISSN 2186-6953
    DOI 10.12938/bmfh.17-007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Karpal tünel sendromu tedavisinde steroid enjeksiyonun uyku hijyeni üzerindeki etkisi.

    Aşkın Turan, Suna / Aydın, Şenay

    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology

    2021  Volume 33, Issue 2, Page(s) 96–102

    Abstract: Objectives: Carpal tunnel syndrome (CTS) is the most seen entrapment neuropathy. CTS is a complex syndrome arisen with entrapment of median nerve at wrist. Pain worst at night, paresthesia, hypoesthesia, paralysis, and muscle atrophy can be seen through ...

    Title translation The effect of steroid injection treatment with carpal tunnel syndrome on sleep hygiene.
    Abstract Objectives: Carpal tunnel syndrome (CTS) is the most seen entrapment neuropathy. CTS is a complex syndrome arisen with entrapment of median nerve at wrist. Pain worst at night, paresthesia, hypoesthesia, paralysis, and muscle atrophy can be seen through nerve entrapment level. Besides, we see negative symptoms for sleep in our practice. It is known the effect of invasive and non-invasive treatments on the sleep. We aimed to search the effect of treatment of CTS on the sleep modalities.
    Methods: In our study, the effect of injection treatment of CTS patients diagnosed clinically with electrophysiological methods in neurology clinic, on sleep modalities. After excluding the secondary reasons of CTS; patients responded to visual analog scale (VAS), symptom, and functional scales of Boston questionnaire (BQ-FS), Leeds Assessment of Neuropathic Symptoms and Signs, Pittsburg sleep quality index (PSQI), insomnia severity index (ISI), sleep hygiene index (SHI), Epworth sleepiness scale, Beck depression scale, and Beck anxiety scale.
    Results: Twenty-nine patients (2 males and 27 females) were enrolled. After treatment, VAS, BQ-FS, LANNS, PSQI, ISI, and SHI both resulted in a significant reduction.
    Conclusion: Sleep hygiene is affected negatively in CTS patients. A healing effect is observed on the quality of sleep impaired by the injection treatment of CTS.
    MeSH term(s) Carpal Tunnel Syndrome/drug therapy ; Female ; Humans ; Male ; Pain Measurement ; Sleep Hygiene ; Steroids ; Visual Analog Scale
    Chemical Substances Steroids
    Language Turkish
    Publishing date 2021-04-12
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1283669-2
    ISSN 1300-0012
    ISSN 1300-0012
    DOI 10.14744/agri.2020.09735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Renalase, Catecholamine and Nitric Oxide Changes Before and After Sodium Nitroprusside Administration to Patients who Develop Post-Coronary Artery By-Pass (CABG) Hypertension.

    Aydin, Suna

    The heart surgery forum

    2018  Volume 21, Issue 5, Page(s) E330–E336

    Abstract: Background: Hypertension develops at a rate of 33 to 70% after Coronary artery bypass grafting (CABG) operations. One of the most commonly used drugs to control hypertension is sodium nitroprusside (SNP). Additionally, renalase enzyme destroys ... ...

    Abstract Background: Hypertension develops at a rate of 33 to 70% after Coronary artery bypass grafting (CABG) operations. One of the most commonly used drugs to control hypertension is sodium nitroprusside (SNP). Additionally, renalase enzyme destroys catecholamines and mediates the regulation (reduction) of blood pressure. Thus, this clinical study aims to reveal how renalase, catecholamines and nitric oxide (NO) change and how certain hemodynamic parameters are affected in randomly and prospectively selected cases who are administered SNP for the treatment of blood pressure elevation within 6 to 8 hours after CABG surgery.
    Methods: The study included 26 patients who developed hypertension after CABG, 12 patients who had normal blood pressure after CABG, and 22 healthy individuals. Renalase and catecholamine levels of the patients were measured using ELISA method and NO levels were determined by spectrophotometry.
    Results: Renalase and NO levels of the patients who developed hypertension after CABG were found statistically significantly lower than those of healthy controls and patients who did not develop hypertension after CABG, while catecholamine levels were significantly higher in the former. After SNP was started, renalase and NO levels increased, and a significant decrease was observed in the catecholamine levels. Additionally, administration of SNP produced a slight increase in the heart rate and a decrease in systolic arterial pressure (SAP), diastolic arterial pressure (DAP) and means arterial pressure (MAP).
    Conclusion: SNP elevates NO and renalase levels; thus, administration of renalase preparations, which act in the destruction of catecholamines to contain persistent hypertension that develops in association with catecholamine elevation after CABG surgery, along with SNP and other medications used to lower blood pressure can be an effective therapeutic method to control hypertension.
    MeSH term(s) Aged ; Biomarkers/blood ; Blood Pressure/drug effects ; Catecholamines/blood ; Coronary Artery Bypass/adverse effects ; Coronary Vessels/physiopathology ; Dose-Response Relationship, Drug ; Enzyme-Linked Immunosorbent Assay ; Female ; Follow-Up Studies ; Humans ; Hypertension/blood ; Hypertension/drug therapy ; Hypertension/etiology ; Male ; Monoamine Oxidase/blood ; Nitric Oxide/blood ; Nitroprusside/administration & dosage ; Postoperative Complications ; Prospective Studies ; Retrospective Studies ; Spectrophotometry ; Treatment Outcome ; Vasodilator Agents/administration & dosage
    Chemical Substances Biomarkers ; Catecholamines ; Vasodilator Agents ; Nitroprusside (169D1260KM) ; Nitric Oxide (31C4KY9ESH) ; Monoamine Oxidase (EC 1.4.3.4) ; renalase (EC 1.4.3.4.)
    Language English
    Publishing date 2018-08-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2069188-9
    ISSN 1522-6662 ; 1098-3511
    ISSN (online) 1522-6662
    ISSN 1098-3511
    DOI 10.1532/hsf.1998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Ultrasound-Guided Combined Greater Occipital Nerve Block at the C2 Level with Trapezius Trigger Point Injection and Supraorbital-Supratrochlear Nerve Block: More Effective on Allodynia and Disability in Chronic Migraine.

    Turan, Suna Aşkın / Aydın, Şenay / Gözükara, Melih G / Çabalar, Murat

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 6, Page(s) 943–951

    Abstract: Background: Chronic migraine (CM) patients with cutaneous allodynia (CA) show a poor response to treatment. Long-term studies have yet to be conducted to demonstrate the efficacy of blocks on CA. This study evaluated the improvement in allodynia and ... ...

    Abstract Background: Chronic migraine (CM) patients with cutaneous allodynia (CA) show a poor response to treatment. Long-term studies have yet to be conducted to demonstrate the efficacy of blocks on CA. This study evaluated the improvement in allodynia and disability in CM treated with ultrasound (US)-guided blocks.
    Methods: In this prospective, non-randomized comparative study, 60 CM patients with CA were evaluated for the clinical effectiveness of the therapy using the numeric rating scale (NRS), headache impact test-6 (HIT-6), brush allodynia test, and allodynia symptom checklist (ASC-12). At the first visit, tenderness in the nerve or trapezius muscle was confirmed in the intervention group. US-guided greater occipital nerve block (GONB), GONB, and trapezius muscle injection (TPI), or GONB, TPI, and peripheral trigeminal nerve block (PTNB), respectively, were performed four times once a week for a month. Initial and third-month assessments were performed.
    Results: The ASC-12 scores decreased in the GONB+TPI+PTNB and GONB groups more than the GONB+TPI group (mean rank, respectively, 26.86, 27.40, 38.39;
    Conclusions: GONB+TPI+PTNB was more successful in alleviating allodynia and disability.
    Language English
    Publishing date 2023-12-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_677_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Entomopathogenic fungi with biological control potential against poultry red mite (Dermanyssus gallinae, Arachnida: Dermanyssidae).

    Bayramoğlu, Miraç / Bayramoğlu, Zeynep / Aydın, Levent / Zengin, Suna Aslı / Çırak, Veli Yılgör / Demirbağ, Zihni / Demir, İsmail

    Veterinary parasitology

    2024  Volume 328, Page(s) 110155

    Abstract: The poultry red mite, Dermanyssus gallinae (Arachnida: Dermanyssidae) is a pest that causes significant economic loss in laying hens for which control methods are limited. In this study, the effects of 20 indigenous fungal strains on poultry red mites in ...

    Abstract The poultry red mite, Dermanyssus gallinae (Arachnida: Dermanyssidae) is a pest that causes significant economic loss in laying hens for which control methods are limited. In this study, the effects of 20 indigenous fungal strains on poultry red mites in chicken farms were investigated. All experiments were conducted under laboratory condition at 28 ± 1 °C and 80 ± 5% humidity. A screening test showed that Metharizium flavoviride strain As-2 and Beauveria bassiana strain Pa4 had the greatest measured effect on D. gallinae at 1 × 10
    Language English
    Publishing date 2024-03-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 196831-2
    ISSN 1873-2550 ; 0304-4017
    ISSN (online) 1873-2550
    ISSN 0304-4017
    DOI 10.1016/j.vetpar.2024.110155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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