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  1. Book ; Online ; E-Book: Environmental Stressors and Oxinflammatory Tissues Responses

    Valacchi, Giuseppe / Daiber, Andreas

    (Oxidative Stress and Disease Series ; Volume 53)

    2024  

    Abstract: Environmental risk factors - noise, air pollution, chemical agents, and ultraviolet radiation - impact human health by contributing to the onset and progression of non-communicable diseases. Accordingly, there is need for preclinical and clinical ... ...

    Author's details edited by Giuseppe Valacchi and Andreas Daiber
    Series title Oxidative Stress and Disease Series ; Volume 53
    Abstract "Environmental risk factors - noise, air pollution, chemical agents, and ultraviolet radiation - impact human health by contributing to the onset and progression of non-communicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensible summary of major findings. This book is a state-of-the-art summary of these myriad severe life stress. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. We emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps"--
    Keywords Pathology, Cellular ; Stress (Physiology)
    Subject code 571.9
    Language English
    Size 1 online resource (302 pages)
    Edition First edition.
    Publisher CRC Press
    Publishing place Boca Raton, FL
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-000-97010-8 ; 9781032357010 ; 978-1-000-97010-4 ; 1032357010
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Modulation of Oxidative Stress

    Saso, Luciano / Giuffre, Alessandro / Valacchi, Giuseppe / Maccarrone, Mauro

    Biochemical, Physiological and Pharmacological Aspects

    2023  

    Subject code 616.39
    Language English
    Size 1 online resource (308 pages)
    Edition 1st ed.
    Publisher Elsevier Science & Technology
    Publishing place San Diego
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9780443192487 ; 0443192480
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Cellular and environmental stressors in biology and medicine

    Valacchi, Giuseppe

    focus on redox reactions

    (Annals of the New York Academy of Sciences ; 1340)

    2015  

    Author's details iss. ed. Giuseppe Valacchi
    Series title Annals of the New York Academy of Sciences ; 1340
    Collection
    Language English
    Size 103 S. : Ill., graph. Darst.
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT018637734
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Environmental stressors in biology and medicine

    Valacchi, Giuseppe

    (Annals of the New York Academy of Sciences ; 1259)

    2012  

    Author's details iss. ed. Giuseppe Valacchi
    Series title Annals of the New York Academy of Sciences ; 1259
    Collection
    Language English
    Size 145 S. : Ill., graph. Darst.
    Publisher Blackwell
    Publishing place Boston, Mass
    Publishing country United States
    Document type Book
    HBZ-ID HT017331387
    ISBN 978-1-57331-870-9 ; 1-57331-870-1
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Oxidants in biology

    Valacchi, Giuseppe

    a question of balance

    2008  

    Author's details Giuseppe Valacchi ed
    Language English
    Size VIII, 327 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer Science+Business Media
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015609025
    ISBN 978-1-4020-8398-3 ; 1-4020-8398-X ; 9781402083990 ; 1402083998
    Database Catalogue ZB MED Medicine, Health

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  6. Article: Cutaneous Redox Senescence.

    Sarandy, Mariáurea Matias / Gonçalves, Reggiani Vilela / Valacchi, Giuseppe

    Biomedicines

    2024  Volume 12, Issue 2

    Abstract: Our current understanding of skin cell senescence involves the role of environmental stressors (UV, ... ...

    Abstract Our current understanding of skin cell senescence involves the role of environmental stressors (UV, O
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12020348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: OxInflammation in Alzheimer's disease.

    Cervellati, Carlo / Zuliani, Giovanni / Valacchi, Giuseppe

    Neural regeneration research

    2023  Volume 18, Issue 12, Page(s) 2709–2710

    Language English
    Publishing date 2023-07-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.374144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial: Cell cycle control as a new therapeutic approach for SARS-CoV-2 infection.

    Rizzo, Roberta / Caccuri, Francesca / Valacchi, Giuseppe / Zauli, Giorgio

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1136277

    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1136277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Redox Regulation of Nucleotide-Binding and Oligomerization Domain-Like Receptors Inflammasome.

    Ferrara, Francesca / Pecorelli, Alessandra / Valacchi, Giuseppe

    Antioxidants & redox signaling

    2023  Volume 39, Issue 10-12, Page(s) 744–770

    Abstract: Significance: ...

    Abstract Significance:
    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2022.0180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Ultraviolet Light Protection: Is It Really Enough?

    Farris, Patricia K / Valacchi, Giuseppe

    Antioxidants (Basel, Switzerland)

    2022  Volume 11, Issue 8

    Abstract: Our current understanding of the pathogenesis of skin aging includes the role of ultraviolet light, visible light, infrared, pollution, cigarette smoke and other environmental exposures. The mechanism of action common to these exposures is the disruption ...

    Abstract Our current understanding of the pathogenesis of skin aging includes the role of ultraviolet light, visible light, infrared, pollution, cigarette smoke and other environmental exposures. The mechanism of action common to these exposures is the disruption of the cellular redox balance by the directly or indirectly increased formation of reactive oxygen species that overwhelm the intrinsic antioxidant defense system, resulting in an oxidative stress condition. Altered redox homeostasis triggers downstream pathways that contribute to tissue oxinflammation (cross-talk between inflammation and altered redox status) and accelerate skin aging. In addition, both ultraviolet light and pollution increase intracellular free iron that catalyzes reactive oxygen species generation via the Fenton reaction. This disruption of iron homeostasis within the cell further promotes oxidative stress and contributes to extrinsic skin aging. More recent studies have demonstrated that iron chelators can be used topically and can enhance the benefits of topically applied antioxidants. Thus, an updated, more comprehensive approach to environmental or atmospheric aging protection should include sun protective measures, broad spectrum sunscreens, antioxidants, chelating agents, and DNA repair enzymes.
    Language English
    Publishing date 2022-07-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox11081484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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