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  1. Article ; Online: Current Trends in Sirtuin Activator and Inhibitor Development.

    Bursch, Karina L / Goetz, Christopher J / Smith, Brian C

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 5

    Abstract: Sirtuins are ... ...

    Abstract Sirtuins are NAD
    MeSH term(s) Humans ; Sirtuins/metabolism ; Sirtuin 1 ; Protein Isoforms/metabolism ; Lysine
    Chemical Substances Sirtuins (EC 3.5.1.-) ; Sirtuin 1 (EC 3.5.1.-) ; Protein Isoforms ; Lysine (K3Z4F929H6)
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29051185
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    Zs.MO 81: Show issues

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  2. Article ; Online: Response to Bender et al.

    Smith, Rebecca L / Brooke, Christopher B

    The Journal of infectious diseases

    2021  Volume 224, Issue 11, Page(s) 1989

    Language English
    Publishing date 2021-10-14
    Publishing country United States
    Document type Research Support, N.I.H., Extramural ; Letter ; Comment
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiab530
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    Uh II Zs.50: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

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  3. Article: Lymphatic Disorders in Patients With Single Ventricle Heart Disease.

    Dori, Yoav / Smith, Christopher L

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 828107

    Abstract: Lymphatic abnormalities in patients with single ventricle physiology can lead to early Fontan failure and severe Fontan complications, such as protein-losing enteropathy (PLE), plastic bronchitis (PB), chylothorax, and edema. Recent developments in ... ...

    Abstract Lymphatic abnormalities in patients with single ventricle physiology can lead to early Fontan failure and severe Fontan complications, such as protein-losing enteropathy (PLE), plastic bronchitis (PB), chylothorax, and edema. Recent developments in lymphatic imaging and interventions have shed new light on the lymphatic dysfunction in this patient population and the role of the lymphatic circulation in PLE, PB, and chylothorax. In this study, we reviewed some of the latest developments in this field and discuss new treatment options for these patients.
    Language English
    Publishing date 2022-06-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.828107
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  4. Article ; Online: An Exploration of Online and In-Person Administration of the Kaufman Brief Intelligence Test, Second Edition (KBIT-2) in Children and Adolescents Being Evaluated for Autism Spectrum Disorder.

    Anbar, Joshua / Metoyer, Maurice / Smith, Christopher J / Matthews, Nicole L

    Journal of autism and developmental disorders

    2024  

    Abstract: Purpose:  Most assessment tools used to diagnose and characterize autism spectrum disorder (ASD) were developed for in-person administration. The coronavirus disease 2019 (COVID-19) pandemic resulted in the need to adapt traditional assessment tools for ...

    Abstract Purpose:  Most assessment tools used to diagnose and characterize autism spectrum disorder (ASD) were developed for in-person administration. The coronavirus disease 2019 (COVID-19) pandemic resulted in the need to adapt traditional assessment tools for online administration with only minimal evidence to support validity of such practices.
    Methods: The current exploratory study compared scores from online administration of the Kaufman Brief Intelligence Test, Second Edition (KBIT-2) during the pandemic to scores derived from follow-up testing using traditional in-person administration. Participants were 47 children and adolescents (M age = 9.48 years, SD = 4.06; 68.10% male) who participated in a telehealth diagnostic evaluation for ASD that included online administration of the KBIT-2. Participants were invited to complete the KBIT-2 a second time during an in-person study visit.
    Results: Pearson's correlation coefficients suggested acceptable to good reliability between online and in-person administration. Although most participants' online and in-person scores were within one standard deviation of each other, results suggested statistically significant differences between scores derived from the two modalities. Additionally, 19-26% of participants (depending on domain examined) had scores that differed by more than one standard deviation. Notably, all but one of these participants was under the age of 12 years.
    Conclusion: Findings suggest that online administration of the KBIT-2 is likely appropriate for older children and adolescents with ASD. However, additional research is needed to test online administration of intellectual assessments for children with ASD.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-024-06323-4
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    Zs.A 765: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Understanding the next circulation: lymphatics and what the future holds.

    Tomasulo, Catherine E / Dori, Yoav / Smith, Christopher L

    Current opinion in cardiology

    2023  Volume 38, Issue 4, Page(s) 369–374

    Abstract: Purpose of review: The lymphatic system was previously considered the forgotten circulation because of an absence of adequate options for imaging and intervention. However, recent advances over the last decade have improved management strategies for ... ...

    Abstract Purpose of review: The lymphatic system was previously considered the forgotten circulation because of an absence of adequate options for imaging and intervention. However, recent advances over the last decade have improved management strategies for patients with lymphatic disease, including chylothorax, plastic bronchitis, ascites, and protein-losing enteropathy.
    Recent findings: New imaging modalities have enabled detailed visualization of lymphatic vessels to allow for a better understanding of the cause of lymphatic dysfunction in a variety of patient subsets. This sparked the development of multiple transcatheter and surgery-based techniques tailored to each patient based on imaging findings. In addition, the new field of precision lymphology has added medical management options for patients with genetic syndromes, who have global lymphatic dysfunction and typically do not respond as well to the more standard lymphatic interventions.
    Summary: Recent developments in lymphatic imaging have given insight into disease processes and changed the way patients are managed. Medical management has been enhanced and new procedures have given patients more options, leading to better long-term results.
    MeSH term(s) Humans ; Heart Defects, Congenital/complications ; Lymphatic System ; Lymphatic Vessels ; Lymphatic Diseases/etiology ; Bronchitis/complications
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 645186-x
    ISSN 1531-7080 ; 0268-4705
    ISSN (online) 1531-7080
    ISSN 0268-4705
    DOI 10.1097/HCO.0000000000001064
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    Zs.A 2556: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Photophysical Studies of Helicate and Mesocate Double-Stranded Dinuclear Ru(II) Complexes.

    Xu, Xinyue / Marlton, Samuel J P / Flint, Kate L / Hudson, Rohan J / Keene, F Richard / Hall, Christopher R / Smith, Trevor A

    The journal of physical chemistry. A

    2024  

    Abstract: The metal-ligand charge transfer ( ...

    Abstract The metal-ligand charge transfer (
    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.4c01996
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  7. Article ; Online: Institutional Variability in Respiratory Support Use for Pediatric Critical Asthma: A Multicenter Retrospective Study.

    Rogerson, Colin M / White, Benjamin R / Smith, Michele / Hogan, Alexander H / Abu-Sultaneh, Samer / Carroll, Christopher L / Shein, Steven L

    Annals of the American Thoracic Society

    2024  Volume 21, Issue 4, Page(s) 612–619

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Child ; Child, Preschool ; Retrospective Studies ; Noninvasive Ventilation ; Asthma/therapy ; Respiration, Artificial ; Hospitalization ; Oxygen Inhalation Therapy ; Respiratory Insufficiency/therapy
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202309-807OC
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    Zs.A 5828: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Longitudinal Follow-Up Study of Social Intervention Outcomes for Children on the Autism Spectrum.

    Lopata, Christopher / Thomeer, Marcus L / Rodgers, Jonathan D / Donnelly, James P / Lodi-Smith, Jennifer

    Journal of autism and developmental disorders

    2024  

    Abstract: A prior randomized trial found a school social intervention yielded significantly better outcomes (social and autism features) immediately following intervention compared to typical school programming (services-as-usual [SAU]) for children on the autism ... ...

    Abstract A prior randomized trial found a school social intervention yielded significantly better outcomes (social and autism features) immediately following intervention compared to typical school programming (services-as-usual [SAU]) for children on the autism spectrum. In that study, children in the SAU condition subsequently completed a summer social intervention. This study tested longer-term maintenance of effects for children who completed both interventions. A total of 103 children (ages 6-12 years) on the autism spectrum enrolled and 102 completed the initial RCT. Following the summer social intervention, 90 children from the original RCT completed the longer-term follow-up study. In addition to baseline and posttest in the initial RCT, children from both groups were tested at three follow-up points (five total testing points). At the time of first longitudinal follow-up testing, the children were 1.25-4.25 years post-intervention (ages 8-15 years). Longitudinal multilevel model analyses (and follow-up contrasts) revealed significant improvements for both groups post-intervention on measures of emotion recognition, autism features, and social skills, indicating maintenance of post-intervention improvements over the three follow-up testing points. No between-group differences were found for autism features or social skills over time; however, the school social intervention may have yielded somewhat better emotion recognition skills. Exploratory tests found that child IQ, language level, and length of time since completing the intervention did not moderate outcomes. Both social interventions yielded positive and durable longer-term improvements for children on the autism spectrum. [ClinicalTrials.gov, NCT03338530; November 8, 2017; original retrospectively registered trial].
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-023-06221-1
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    Zs.A 765: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Mixed-methods examination of attitudes and behaviors related to COVID-19 vaccines among parents of children with autism and autistic adults.

    Mitchell, Melissa M / Klott, Adriana / Scholtes, Jared / Braden, B Blair / Smith, Christopher J / Matthews, Nicole L

    Vaccine

    2024  Volume 42, Issue 4, Page(s) 937–944

    Abstract: Increased risks associated with Coronavirus disease 2019 (COVID-19) among individuals with autism spectrum disorder (ASD) combined with previous reports of heightened vaccine hesitancy among parents of children with ASD indicate the need for a better ... ...

    Abstract Increased risks associated with Coronavirus disease 2019 (COVID-19) among individuals with autism spectrum disorder (ASD) combined with previous reports of heightened vaccine hesitancy among parents of children with ASD indicate the need for a better understanding of attitudes and behaviors related to COVID-19 vaccines among the ASD community. This study is the first to our knowledge to use a mixed-methods approach to understand attitudes toward COVID-19 vaccines among parents of children with ASD and autistic adults. Participants were 135 members of the ASD community residing in the state of Arizona (99 parents of children with ASD and 36 autistic adults) who responded to the third (Spring 2021) and fourth (Summer 2021) time points of a larger longitudinal online survey. Quantitative findings indicated that autistic adults had slightly more favorable attitudes toward COVID-19 vaccines than parents, and attitudes in both subsamples became more positive over time. However, both parents and autistic adults reported COVID-19 vaccine uptake that was consistent with or better than the general population at both time points. Thematic analysis of responses to open-ended questions identified five themes that characterized factors that contributed to participants' decisions about COVID-19 vaccinations, including: (1) Desiring a Return to Normalcy, (2) Protection of Self and Others, (3) Previous Experience with COVID-19 (4) Science and Medical Professionals,and (5) Skepticism Regarding Safety, Effectiveness, and Need. Current findings combined with emerging literature paint a relatively optimistic picture about COVID-19 vaccine acceptance in the ASD community.
    MeSH term(s) Child ; Adult ; Humans ; Autistic Disorder ; COVID-19 Vaccines ; Autism Spectrum Disorder ; COVID-19/prevention & control ; Parents
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2024-01-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2024.01.011
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    Zs.MO 458: Show issues

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  10. Article: Effects of simulated hypo-gravity on lower limb kinematic and electromyographic variables during anti-gravitational treadmill walking.

    Malaya, Christopher A / Parikh, Pranav J / Smith, Dean L / Riaz, Arshia / Chandrasekaran, Subhalakshmi / Layne, Charles S

    Frontiers in physiology

    2023  Volume 14, Page(s) 1141015

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-06-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1141015
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