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  1. Article: [EPITHELIAL-IMMUNE MICROENVIRONMENT (EIME) IN ATOPIC DERMATITIS].

    Dainichi, Teruki

    Arerugi = [Allergy

    2020  Volume 69, Issue 8, Page(s) 662–668

    MeSH term(s) Dermatitis, Atopic/immunology ; Epithelium/immunology ; Humans ; Skin/immunology
    Language Japanese
    Publishing date 2020-10-13
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    DOI 10.15036/arerugi.69.662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Necessary and sufficient factors of keratinocytes in psoriatic dermatitis.

    Dainichi, Teruki / Matsumoto, Reiko / Sakurai, Kenji / Kabashima, Kenji

    Frontiers in immunology

    2024  Volume 15, Page(s) 1326219

    MeSH term(s) Humans ; Keratinocytes ; Psoriasis ; Dermatitis
    Language English
    Publishing date 2024-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1326219
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multiple cutaneous focal mucinosis in a patient with atopic dermatitis.

    Fujioka, Kiriko / Kita, Marina / Iwata, Masashi / Moriue, Tetsuya / Dainichi, Teruki

    The Journal of dermatology

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Inflammatory loops in the epithelial-immune microenvironment of the skin and skin appendages in chronic inflammatory diseases.

    Dainichi, Teruki / Iwata, Masashi

    Frontiers in immunology

    2023  Volume 14, Page(s) 1274270

    Abstract: The epithelial-immune microenvironment (EIME) of epithelial tissues has five common elements: (1) microbial flora, (2) barrier, (3) epithelial cells, (4) immune cells, and (5) peripheral nerve endings. EIME provides both constant defense and situation- ... ...

    Abstract The epithelial-immune microenvironment (EIME) of epithelial tissues has five common elements: (1) microbial flora, (2) barrier, (3) epithelial cells, (4) immune cells, and (5) peripheral nerve endings. EIME provides both constant defense and situation-specific protective responses through three-layered mechanisms comprising barriers, innate immunity, and acquired immunity. The skin is one of the largest organs in the host defense system. The interactions between the five EIME elements of the skin protect against external dangers from the environment. This dysregulation can result in the generation of inflammatory loops in chronic inflammatory skin diseases. Here, we propose an understanding of EIME in chronic skin diseases, such as atopic dermatitis, psoriasis, systemic lupus erythematosus, alopecia areata, and acne vulgaris. We discuss the current treatment strategies targeting their inflammatory loops and propose possible therapeutic targets in the future.
    MeSH term(s) Humans ; Skin ; Psoriasis ; Skin Diseases ; Dermatitis, Atopic ; Epithelium
    Language English
    Publishing date 2023-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1274270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Solitary ectopic extramammary Paget's disease in the epigastric region.

    Izumi, Maiko / Kaku, Yo / Kagawa, Seiko / Dainichi, Teruki

    European journal of dermatology : EJD

    2023  Volume 33, Issue 4, Page(s) 435–436

    MeSH term(s) Humans ; Paget Disease, Extramammary/diagnosis ; Skin Neoplasms/surgery ; Abdominal Wall
    Language English
    Publishing date 2023-10-12
    Publishing country France
    Document type Journal Article
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2023.4518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alopecia areata: What's new in the epidemiology, comorbidities, and pathogenesis?

    Dainichi, Teruki / Iwata, Masashi / Kaku, Yo

    Journal of dermatological science

    2023  Volume 112, Issue 3, Page(s) 120–127

    Abstract: Background: Alopecia areata (AA) is a common, acquired, and nonscarring type of hair loss that affects people of every generation and is intractable in severe and relapsing cases. Patients with AA, especially those with greater scalp involvement, have ... ...

    Abstract Background: Alopecia areata (AA) is a common, acquired, and nonscarring type of hair loss that affects people of every generation and is intractable in severe and relapsing cases. Patients with AA, especially those with greater scalp involvement, have poor health-related quality-of-life scores.
    Purpose: Following our previous review article in the April 2017 issue of the Journal of Dermatological Science, we aim to provide a pair of review articles on recent progress in multidisciplinary approaches to AA.
    Main findings: We found more than 1800 publications on AA from July 2016 to December 2022.
    Conclusions: In this review, we focused on the latest information on the epidemiology, comorbidities, and pathogenesis of AA.
    MeSH term(s) Humans ; Alopecia Areata/epidemiology ; Alopecia Areata/pathology ; Alopecia ; Comorbidity ; Quality of Life ; Recurrence
    Language English
    Publishing date 2023-10-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2023.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Alopecia areata: What's new in the diagnosis and treatment with JAK inhibitors?

    Dainichi, Teruki / Iwata, Masashi / Kaku, Yo

    The Journal of dermatology

    2023  Volume 51, Issue 2, Page(s) 196–209

    Abstract: Alopecia areata (AA) affects individuals of all ages and is intractable in severe relapsing cases. Dermatologists and other healthcare providers should consider AA in the medical context and prioritize treatment. Several randomized controlled clinical ... ...

    Abstract Alopecia areata (AA) affects individuals of all ages and is intractable in severe relapsing cases. Dermatologists and other healthcare providers should consider AA in the medical context and prioritize treatment. Several randomized controlled clinical studies on Janus kinase (JAK) inhibitors with different specificities for the treatment of AA are ongoing. These studies have encouraged us to appreciate the importance of a definitive diagnosis and accurate evaluation of AA before and during treatment. Following our previous review article in 2017, here we provide the second part of this two-review series on the recent progress in the multidisciplinary approaches to AA from more than 1800 articles published between July 2016 and December 2022. This review focuses on the evaluation, diagnosis, and treatment of AA. We also provide the latest information on the safety and efficacy of JAK inhibitors for the treatment of AA and describe their mechanisms of action.
    MeSH term(s) Humans ; Alopecia Areata/diagnosis ; Alopecia Areata/drug therapy ; Janus Kinase Inhibitors/pharmacology ; Janus Kinase Inhibitors/therapeutic use ; Treatment Outcome
    Chemical Substances Janus Kinase Inhibitors
    Language English
    Publishing date 2023-12-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Alopecia areata in a patient with cytotoxic T lymphocyte antigen-4 haploinsufficiency successfully treated with topical delgocitinib ointment.

    Senda, Akiyoshi / Shibuya, Rintaro / Miyake, Toshiya / Nomura, Takashi / Dainichi, Teruki / Kabashima, Kenji

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  Volume 38, Issue 1, Page(s) e51–e53

    MeSH term(s) Humans ; Alopecia Areata/drug therapy ; Alopecia Areata/genetics ; T-Lymphocytes, Cytotoxic ; Ointments ; Haploinsufficiency
    Chemical Substances delgocitinib (9L0Q8KK220) ; Ointments
    Language English
    Publishing date 2023-08-26
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Case of Atopic Dermatitis with High Serum Levels of Anti-BP180 Antibody and Dyshidrosiform Blisters Limited to the Palms and Soles.

    Kaisho, Junichi / Honda, Tetsuya / Dainichi, Teruki / Kabashima, Kenji

    Acta dermato-venereologica

    2021  Volume 101, Issue 3, Page(s) adv00411

    MeSH term(s) Blister ; Dermatitis, Atopic/diagnosis ; Dermatitis, Atopic/drug therapy ; Eczema ; Humans ; Pemphigoid, Bullous ; Skin Abnormalities
    Language English
    Publishing date 2021-03-09
    Publishing country Sweden
    Document type Case Reports ; Journal Article
    ZDB-ID 80007-7
    ISSN 1651-2057 ; 0001-5555
    ISSN (online) 1651-2057
    ISSN 0001-5555
    DOI 10.2340/00015555-3773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Necrotizing fasciitis with slow progression in a patient with rheumatoid arthritis receiving tocilizumab

    Goto, Kazuya / Kogame, Toshiaki / Kusuba, Nobuhiro / Endo, Yuichiro / Dainichi, Teruki / Kabashima, Kenji

    European journal of dermatology : EJD

    2022  Volume 32, Issue 2, Page(s) 279–280

    Title translation Necrotizing fasciitis with slow progression in a patient with rheumatoid arthritis receiving tocilizumab.
    MeSH term(s) Antibodies, Monoclonal, Humanized/therapeutic use ; Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Fasciitis, Necrotizing/therapy ; Humans
    Chemical Substances Antibodies, Monoclonal, Humanized ; Antirheumatic Agents ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2022-07-22
    Publishing country France
    Document type Journal Article
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2022.4249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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