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  1. Article: PET evaluation of lung cancer.

    Bunyaviroch, Tira / Coleman, R Edward

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2006  Volume 47, Issue 3, Page(s) 451–469

    MeSH term(s) Fluorodeoxyglucose F18 ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/secondary ; Positron-Emission Tomography/methods ; Positron-Emission Tomography/trends ; Practice Guidelines as Topic ; Practice Patterns, Physicians'/trends ; Radiopharmaceuticals ; Risk Assessment/methods ; Risk Factors ; Solitary Pulmonary Nodule/diagnostic imaging ; Solitary Pulmonary Nodule/secondary
    Chemical Substances Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2006-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0161-5505 ; 0097-9058 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0161-5505 ; 0097-9058 ; 0022-3123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Optimized scintigraphic evaluation of infection and inflammation: role of single-photon emission computed tomography/computed tomography fusion imaging.

    Bunyaviroch, Tira / Aggarwal, Atul / Oates, M Elizabeth

    Seminars in nuclear medicine

    2006  Volume 36, Issue 4, Page(s) 295–311

    Abstract: Gallium-67 citrate and radiolabeled white blood cells have become standard inflammation/infection-seeking agents whereas other agents, such as (99m)Tc diphosphonates, commonly are used to infer an infectious process. These radiopharmaceuticals reflect ... ...

    Abstract Gallium-67 citrate and radiolabeled white blood cells have become standard inflammation/infection-seeking agents whereas other agents, such as (99m)Tc diphosphonates, commonly are used to infer an infectious process. These radiopharmaceuticals reflect physiologic and pathologic function rather than anatomical abnormality. In the clinical setting, it is often necessary to correlate these functional studies with anatomical imaging. The advent of single-photon emission computed tomography, as well as positron emission tomography, provides tomographic images for direct correlation to anatomic modalities such as computed tomography and magnetic resonance imaging. The methods by which these functional and anatomic imaging modalities are correlated include side-by-side, software, and hardware fusion. Clinically, fusion imaging has been applied primarily to oncologic and neurologic applications. The literature supports the premise that multimodality fusion would increase the specificity of the physiologic modality and increase the sensitivity of the anatomic modality. Our institution uses software fusion to aid in the diagnosis of infection and inflammation. Through case vignettes, we illustrate applications for single-photon emission computed tomography/computed tomography fusion for the diagnosis of infection and inflammation in multiple organ systems.
    MeSH term(s) Equipment Design ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods ; Infection/diagnosis ; Inflammation/diagnosis ; Subtraction Technique ; Technology Assessment, Biomedical ; Tomography, Emission-Computed, Single-Photon/methods ; Tomography, Emission-Computed, Single-Photon/trends ; Tomography, X-Ray Computed/methods ; Tomography, X-Ray Computed/trends
    Language English
    Publishing date 2006-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 120248-0
    ISSN 0001-2998
    ISSN 0001-2998
    DOI 10.1053/j.semnuclmed.2006.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Quantitative effects of contrast enhanced CT attenuation correction on PET SUV measurements.

    Bunyaviroch, Tira / Turkington, Timothy G / Wong, Terence Z / Wilson, John W / Colsher, James G / Coleman, R Edward

    Molecular imaging and biology

    2007  Volume 10, Issue 2, Page(s) 107–113

    Abstract: Purpose: The presence of contrast materials on computed tomography (CT) images can cause problems in the attenuation correction of positron emission tomography (PET) images. These are because of errors converting the CT attenuation of contrast to 511- ... ...

    Abstract Purpose: The presence of contrast materials on computed tomography (CT) images can cause problems in the attenuation correction of positron emission tomography (PET) images. These are because of errors converting the CT attenuation of contrast to 511-keV attenuation and by the change in tissue enhancement over the duration of the PET emission scan. Newer CT-based attenuation correction (CTAC) algorithms have been developed to reduce these errors.
    Methods: To evaluate the effectiveness of the modified CTAC technique, we performed a retrospective analysis on 20 patients, comparing PET images using unenhanced and contrast-enhanced CT scans for attenuation correction. A phantom study was performed to simulate the effects of contrast on radiotracer concentration measurements.
    Results: There was a maximum difference in calculated radiotracer concentrations of 5.9% within the retrospective data and 7% within the phantom data.
    Conclusion: Using a CTAC algorithm that de-emphasizes high-density areas, contrast-enhanced CT can be used for attenuation mapping without significant errors in quantitation.
    MeSH term(s) Algorithms ; Contrast Media/pharmacokinetics ; Humans ; Phantoms, Imaging ; Positron-Emission Tomography/instrumentation ; Positron-Emission Tomography/methods ; Tomography, X-Ray Computed/instrumentation ; Tomography, X-Ray Computed/methods
    Chemical Substances Contrast Media
    Language English
    Publishing date 2007-12-21
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2079160-4
    ISSN 1860-2002 ; 1536-1632
    ISSN (online) 1860-2002
    ISSN 1536-1632
    DOI 10.1007/s11307-007-0126-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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