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  1. Article ; Online: Anithiactin D, a Phenylthiazole Natural Product from Mudflat-Derived

    Pulat, Sultan / Yang, Inho / Lee, Jihye / Hwang, Sunghoon / Zhou, Rui / Gamage, Chathurika D B / Varlı, Mücahit / Taş, İsa / Yang, Yi / Park, So-Yeon / Hong, Ahreum / Kim, Jeong-Hyeon / Oh, Dong-Chan / Kim, Hangun / Nam, Sang-Jip / Kang, Heonjoong

    Marine drugs

    2024  Volume 22, Issue 2

    Abstract: Anithiactin D ( ...

    Abstract Anithiactin D (
    MeSH term(s) Humans ; Cell Line, Tumor ; Caco-2 Cells ; Streptomyces/metabolism ; A549 Cells ; rho GTP-Binding Proteins/metabolism ; Cell Movement ; Epithelial-Mesenchymal Transition ; Neoplasms
    Chemical Substances rho GTP-Binding Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md22020088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Decomposition of methanol-d

    Liao, Guan-Jr / Hsueh, Wen-Hao / Yen, Yu-Hsiang / Shih, Yi-Chan / Wang, Chia-Hsin / Wang, Jeng-Han / Luo, Meng-Fan

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 6, Page(s) 5059–5069

    Abstract: The decomposition of methanol-d ...

    Abstract The decomposition of methanol-d
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05303b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Complete nucleotide sequence of chrysanthemum virus D, a polero-like virus.

    Igori, Davaajargal / Kim, Se Eun / Kwon, Jeong A / Park, Yang Chan / Moon, Jae Sun

    Archives of virology

    2024  Volume 169, Issue 2, Page(s) 28

    Abstract: A putative new polerovirus, named "chrysanthemum virus D" (ChVD), was detected ...

    Abstract A putative new polerovirus, named "chrysanthemum virus D" (ChVD), was detected in a Chrysanthemum morifolium plant in South Korea. The virus was identified by high-throughput sequencing and confirmed by reverse transcription polymerase chain reaction. The entire ChVD genome is composed of 5,963 nucleotides and contains seven open reading frames (ORF0-5 and ORF3a), which are arranged similarly to those of other poleroviruses. These ORFs encode the putative proteins P0-5 and P3a, respectively. Pairwise amino acid sequence comparisons showed that the ChVD P0-5 and P3a proteins have 30.45-75% sequence identity to the corresponding proteins of other members of the genus Polerovirus. Since one of the species demarcation criteria for the genus Polerovirus is > 10% difference in the amino acid sequence of any gene product, the sequence comparisons indicate that ChVD represents a new species in this genus. Phylogenetic analysis of the P1-P2 and P3 amino acid sequences further indicate that ChVD is a novel polerovirus.
    MeSH term(s) Base Sequence ; Phylogeny ; Chrysanthemum/genetics ; Genome, Viral ; Plant Diseases ; RNA, Viral/genetics ; Luteoviridae/genetics ; Open Reading Frames ; High-Throughput Nucleotide Sequencing
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2024-01-12
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-023-05924-1
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    In stock of ZB MED Cologne/Königswinter

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  4. Article: D-optimal Design Optimization of Solvent Mixture for Flavonoid Extraction from

    Sanjaya, I Putu Wahyu / Sudarsono / Chan, Ming-Tsair / Sukma, Dewi / Buchori, Ade / Putra, Raihan Permana / Nurcholis, Waras

    Journal of pharmacy & bioallied sciences

    2024  Volume 16, Issue 1, Page(s) 1–7

    Abstract: Aims: This study aimed to optimize the extraction of flavonoids and antioxidants from : Method: The total flavonoid content (TFC) and antioxidant activity were evaluated using the colorimetric method and ferric-reducing antioxidant power (FRAP), ... ...

    Abstract Aims: This study aimed to optimize the extraction of flavonoids and antioxidants from
    Method: The total flavonoid content (TFC) and antioxidant activity were evaluated using the colorimetric method and ferric-reducing antioxidant power (FRAP), respectively. Maceration extracts from fresh leaves were used for the analysis. The study used the Design Expert 13.0 program to optimize the solvents (water, acetone, and methanol) and their combined ratio.
    Result: The results showed that 100% acetone was the best solvent for both responses, with a desirability value of 0.884, TFC of 0.434 mg QE/g fresh weight (FW) and FRAP of 713.53 μmol TE/g FW. Screening of the most potent
    Conclusion: This study demonstrates an easy and useful way to obtain flavonoids and antioxidants from
    Language English
    Publishing date 2024-03-21
    Publishing country India
    Document type Journal Article
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.jpbs_372_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Vitamin D

    Chan, Hung / Li, Qing / Wang, Xiansong / Liu, Wing Yingzhi / Hu, Wei / Zeng, Judeng / Xie, Chuan / Kwong, Thomas Ngai Yeung / Ho, Idy Hiu Ting / Liu, Xiaodong / Chen, Huarong / Yu, Jun / Ko, Ho / Chan, Raphael Chiu Yeung / Ip, Margaret / Gin, Tony / Cheng, Alfred Sze Lok / Zhang, Lin / Chan, Matthew Tak Vai /
    Wong, Sunny Hei / Wu, William Ka Kei

    Autophagy

    2022  Volume 18, Issue 9, Page(s) 2050–2067

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    MeSH term(s) Animals ; Autophagy ; Bacterial Proteins/metabolism ; Bacterial Toxins/pharmacology ; Carbamazepine/metabolism ; Carbamazepine/pharmacology ; Cholecalciferol/pharmacology ; Clostridioides difficile ; Clostridium Infections/metabolism ; Hydrogen-Ion Concentration ; Inflammation/metabolism ; Lysosomes/metabolism ; Macrophages/metabolism ; Mice ; NF-kappa B/metabolism ; Sequestosome-1 Protein/metabolism ; Vacuolar Proton-Translocating ATPases/metabolism
    Chemical Substances Bacterial Proteins ; Bacterial Toxins ; NF-kappa B ; Sequestosome-1 Protein ; Cholecalciferol (1C6V77QF41) ; Carbamazepine (33CM23913M) ; Vacuolar Proton-Translocating ATPases (EC 3.6.1.-)
    Language English
    Publishing date 2022-01-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2021.2016004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: 1,25-dihydroxyvitamin D

    Wi, Dain / Park, Chan Yoon

    Nutrition research and practice

    2023  Volume 18, Issue 1, Page(s) 1–18

    Abstract: ... response and leads to metabolic diseases. However, the association between vitamin D and adipose ER stress ... remains poorly understood. In this study, we investigated whether 1,25-dihydroxyvitamin D: Materials ...

    Abstract Background/objectives: Endoplasmic reticulum (ER) stress in adipose tissue causes an inflammatory response and leads to metabolic diseases. However, the association between vitamin D and adipose ER stress remains poorly understood. In this study, we investigated whether 1,25-dihydroxyvitamin D
    Materials/methods: 3T3-L1 cells were treated with different concentrations (i.e., 10-100 nM) of 1,25(OH)
    Results: Treatment with 1,25(OH)
    Conclusions: Our data suggest that 1,25(OH)
    Language English
    Publishing date 2023-12-21
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2387946-4
    ISSN 2005-6168 ; 1976-1457
    ISSN (online) 2005-6168
    ISSN 1976-1457
    DOI 10.4162/nrp.2024.18.1.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7762: Show issues

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  7. Article ; Online: Inhibition of cellular factor TM6SF2 suppresses secretion pathways of Hepatitis B, Hepatitis C and Hepatitis D viruses.

    Tu, Thomas / Ajoyan, Harout / Nur Umami, Rifqiyah / Veeraraghavan, Vaishnavi / Boldbaatar, Delgerbat / Najim, Mustafa Ahmed M / Khan, Anis / Bayoumi, Ali / Ho, Vikki / Eslam, Mohammed / Berg, Thomas / Chan, Henry L Y / George, Jacob / Douglas, Mark W

    The Journal of infectious diseases

    2024  

    Abstract: Chronic viral hepatitis is caused by hepatitis B virus, hepatitis C virus or hepatitis D virus (HBV ...

    Abstract Chronic viral hepatitis is caused by hepatitis B virus, hepatitis C virus or hepatitis D virus (HBV, HCV, and HDV). Despite different replication strategies, all these viruses rely on secretion through the host endoplasmic reticulum-Golgi pathway, providing potential host targets for antiviral therapy. Knockdown of transmembrane 6 superfamily member 2 (TM6SF2) in virus cell culture models reduced secretion of infectious HCV virions, HDV virions and HBV subviral particles. Moreover, in a cohort of people with hepatitis B a TM6SF2 polymorphism (rs58542926 CT/TT, which causes protein misfolding and reduced TM6SF2 in the liver) correlated with lower concentrations of subviral particles in blood, complementing our previous work showing decreased HCV viral load in people with this polymorphism. In conclusion, the host protein TM6SF2 plays a key role in secretion of HBV, HCV and HDV, providing the potential for novel pan-viral agents to treat people with chronic viral hepatitis.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiae098
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    Zs.MO 445: Show issues

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  8. Article ; Online: Artérite gigantocellulaire compliquée d’ischémie du segment antérieur : à propos d’un cas.

    Simon, A F / Chan, G / Williamson, W

    Journal francais d'ophtalmologie

    2023  Volume 47, Issue 1, Page(s) 103947

    Title translation Anterior segment ischemia in giant cell arteritis: A case report.
    MeSH term(s) Humans ; Giant Cell Arteritis/complications ; Giant Cell Arteritis/diagnosis ; Eye Diseases/complications ; Optic Neuropathy, Ischemic/diagnosis ; Optic Neuropathy, Ischemic/etiology ; Ischemia/etiology ; Ischemia/complications
    Language French
    Publishing date 2023-09-22
    Publishing country France
    Document type Case Reports ; Letter
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2023.08.005
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    In stock of ZB MED Cologne/Königswinter

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  9. Article ; Online: Latent TB Infection, Vitamin D Status and COVID-19 Severity in Mongolian Patients.

    Ganmaa, Davaasambuu / Chinbayar, Tserendorj / Khudaykov, Polyna / Nasantogtoh, Erdenebileg / Ariunbuyan, Sukhbaatar / Enkhtsetseg, Tserenkhuu / Sarangua, Ganbold / Chan, Andrew / Tserendagva, Dalkh

    Nutrients

    2023  Volume 15, Issue 18

    Abstract: We aimed to determine potential risk factors for COVID-19 severity including serum vitamin D levels ... OR = 10.6 [1.2; 92.0] 95% CI). Severe vitamin D deficiency (25(OH)D < 10 ng/mL) was present in 32 ...

    Abstract We aimed to determine potential risk factors for COVID-19 severity including serum vitamin D levels and latent TB infection among Mongolian inpatients diagnosed with COVID-19, and to study the effects of disease complications and treatment outcomes. This study included patients admitted to the Mongolian National Center for Communicable Disease, a main referral center for infectious disease in Mongolia, with COVID-19 ascertained by a positive PCR test. Patients' demographic, clinical, and laboratory data were analyzed. Of the 270 patients enrolled, 125 (46%) had mild-to-moderate illness, 86 (32%) had severe illness, and 59 (22%) had critical illness. Ten (91%) of the 11 patients who had active TB were hospitalized with severe or critical COVID-19, suggesting that they had a higher risk of falling into the severe category (OR = 10.6 [1.2; 92.0] 95% CI). Severe vitamin D deficiency (25(OH)D < 10 ng/mL) was present in 32% of the patients, but was not significantly associated with the severity of illness (
    MeSH term(s) Humans ; Male ; Animals ; Female ; Vitamin D ; COVID-19 Vaccines ; Latent Tuberculosis ; COVID-19/epidemiology ; Vitamins ; Gerbillinae
    Chemical Substances Vitamin D (1406-16-2) ; COVID-19 Vaccines ; Vitamins
    Language English
    Publishing date 2023-09-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15183979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In Vivo and In Vitro Evidence for an Interplay between the Glucocorticoid Receptor and the Vitamin D Receptor Signaling.

    Bagnoud, Maud / Remlinger, Jana / Massy, Marine / Lodygin, Dmitri / Salmen, Anke / Chan, Andrew / Lühder, Fred / Hoepner, Robert

    Cells

    2023  Volume 12, Issue 18

    Abstract: Our previous work demonstrated that vitamin D (VitD) reduces ...

    Abstract Our previous work demonstrated that vitamin D (VitD) reduces experimental autoimmune encephalomyelitis (EAE) disease severity in wild-type (WT) but not in T cell-specific glucocorticoid (GC) receptor (GR)-deficient (GR
    MeSH term(s) Mice ; Animals ; Receptors, Glucocorticoid/metabolism ; Receptors, Calcitriol/metabolism ; Vitamin D/pharmacology ; Glucocorticoids/pharmacology ; Signal Transduction ; Encephalomyelitis, Autoimmune, Experimental ; Vitamins
    Chemical Substances Receptors, Glucocorticoid ; Receptors, Calcitriol ; Vitamin D (1406-16-2) ; Glucocorticoids ; Vitamins
    Language English
    Publishing date 2023-09-15
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12182291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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