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Article ; Online: Health to Eat: A Smart Plate with Food Recognition, Classification, and Weight Measurement for Type-2 Diabetic Mellitus Patients' Nutrition Control.

Joshua, Salaki Reynaldo / Shin, Seungheon / Lee, Je-Hoon / Kim, Seong Kun

2023 Volume 23, Issue 3

Abstract: The management of type 2 diabetes mellitus (T2DM) is generally not only focused on pharmacological therapy. Medical nutrition therapy is often forgotten by patients for several reasons, such as difficulty determining the right nutritional pattern for ... ...

Abstract	The management of type 2 diabetes mellitus (T2DM) is generally not only focused on pharmacological therapy. Medical nutrition therapy is often forgotten by patients for several reasons, such as difficulty determining the right nutritional pattern for themselves, regulating their daily nutritional patterns, or even not heeding nutritional diet recommendations given by doctors. Management of nutritional therapy is one of the important efforts that can be made by diabetic patients to prevent an increase in the complexity of the disease. Setting a diet with proper nutrition will help patients manage a healthy diet. The development of Smart Plate Health to Eat is a technological innovation that helps patients and users know the type of food, weight, and nutrients contained in certain foods. This study involved 50 types of food with a total of 30,800 foods using the YOLOv5s algorithm, where the identification, measurement of weight, and nutrition of food were investigated using a Chenbo load cell weight sensor (1 kg), an HX711 weight weighing A/D module pressure sensor, and an IMX219-160 camera module (waveshare). The results of this study showed good identification accuracy in the analysis of four types of food: rice (58%), braised quail eggs in soy sauce (60%), spicy beef soup (62%), and dried radish (31%), with accuracy for weight and nutrition (100%).
MeSH term(s)	Animals ; Cattle ; Humans ; Diabetes Mellitus, Type 2 ; Diet ; Nutritional Status ; Nutrients ; Eggs
Language	English
Publishing date	2023-02-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23031656
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Biochemical Impact of Extracting an Embedded Adenylate Kinase Domain Using Circular Permutation.

Coleman, Tom / Shin, John / Silberg, Jonathan J / Shamoo, Yousif / Atkinson, Joshua T

Biochemistry

2024 Volume 63, Issue 5, Page(s) 599–609

Abstract: Adenylate kinases (AKs) have evolved AMP-binding and lid domains that are encoded as continuous polypeptides embedded at different locations within the discontinuous polypeptide encoding the core domain. A prior study showed that AK homologues of ... ...

Abstract	Adenylate kinases (AKs) have evolved AMP-binding and lid domains that are encoded as continuous polypeptides embedded at different locations within the discontinuous polypeptide encoding the core domain. A prior study showed that AK homologues of different stabilities consistently retain cellular activity following circular permutation that splits a region with high energetic frustration within the AMP-binding domain into discontinuous fragments. Herein, we show that mesophilic and thermophilic AKs having this topological restructuring retain activity and substrate-binding characteristics of the parental AK. While permutation decreased the activity of both AK homologues at physiological temperatures, the catalytic activity of the thermophilic AK increased upon permutation when assayed >30 °C below the melting temperature of the native AK. The thermostabilities of the permuted AKs were uniformly lower than those of native AKs, and they exhibited multiphasic unfolding transitions, unlike the native AKs, which presented cooperative thermal unfolding. In addition, proteolytic digestion revealed that permutation destabilized each AK in differing manners, and mass spectrometry suggested that the new termini within the AMP-binding domain were responsible for the increased proteolysis sensitivity. These findings illustrate how changes in contact order can be used to tune enzyme activity and alter folding dynamics in multidomain enzymes.
MeSH term(s)	Adenylate Kinase/chemistry ; Amino Acid Sequence ; Peptides ; Temperature
Chemical Substances	Adenylate Kinase (EC 2.7.4.3) ; Peptides
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1108-3
ISSN	1520-4995 ; 0006-2960
ISSN (online)	1520-4995
ISSN	0006-2960
DOI	10.1021/acs.biochem.3c00605
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Zs.A 217: Show issues

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Article: Gender-Affirming Surgery: Perioperative Medical Care.

Shin, Sangyoon Jason / Kumar, Anish / Safer, Joshua D

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

2022 Volume 28, Issue 4, Page(s) 420–424

Abstract: Objective: Gender-affirming surgeries are becoming increasingly common in the United States. For many transgender and gender-diverse patients, gender-affirming surgery is a critical aspect of their overall health and wellness and has a significant ... ...

Abstract	Objective: Gender-affirming surgeries are becoming increasingly common in the United States. For many transgender and gender-diverse patients, gender-affirming surgery is a critical aspect of their overall health and wellness and has a significant impact on their social functioning. Although often the role of the primary care provider, endocrinology specialists may also need to counsel their patients and collaborate with surgical teams. Methods: This narrative review provides an overview of the preoperative assessment and perioperative management for the most common gender-affirming surgeries. Results: Preoperative assessment prior to gender-affirming surgeries can resemble assessment for other surgeries. Conclusion: In the absence of data specific to gender-affirming surgeries, risk stratification and amelioration must use surrogate data from other populations.
MeSH term(s)	Gender Identity ; Humans ; Perioperative Care ; Sex Reassignment Surgery/methods ; Transgender Persons ; Transsexualism/surgery ; United States
Language	English
Publishing date	2022-02-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1473503-9
ISSN	1530-891X
ISSN	1530-891X
DOI	10.1016/j.eprac.2022.02.007
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Zs.A 5034: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: 3D-integrated multilayered physical reservoir array for learning and forecasting time-series information.

Choi, Sanghyeon / Shin, Jaeho / Park, Gwanyeong / Eo, Jung Sun / Jang, Jingon / Yang, J Joshua / Wang, Gunuk

Nature communications

2024 Volume 15, Issue 1, Page(s) 2044

Abstract: A wide reservoir computing system is an advanced architecture composed of multiple reservoir layers in parallel, which enables more complex and diverse internal dynamics for multiple time-series information processing. However, its hardware ... ...

Abstract	A wide reservoir computing system is an advanced architecture composed of multiple reservoir layers in parallel, which enables more complex and diverse internal dynamics for multiple time-series information processing. However, its hardware implementation has not yet been realized due to the lack of a high-performance physical reservoir and the complexity of fabricating multiple stacks. Here, we achieve a proof-of-principle demonstration of such hardware made of a multilayered three-dimensional stacked 3 × 10 × 10 tungsten oxide memristive crossbar array, with which we further realize a wide physical reservoir computing for efficient learning and forecasting of multiple time-series data. Because a three-layer structure allows the seamless and effective extraction of intricate three-dimensional local features produced by various temporal inputs, it can readily outperform two-dimensional based approaches extensively studied previously. Our demonstration paves the way for wide physical reservoir computing systems capable of efficiently processing multiple dynamic time-series information.
Language	English
Publishing date	2024-03-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-46323-7
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Article: A Novel Curriculum for Internal Medicine Residents to Care for High-Need, High-Cost Patients.

Khalili, Joshua / Jeong, Jiyeon / Tibbe, Tristan D / Sim, Myung-Shin / Yoo, Sun M

Journal of medical education and curricular development

2024 Volume 11, Page(s) 23821205241246889

Abstract: Objectives: High-need, high-cost (HNHC) patients represent a small proportion of patients in the US, but result in disproportionately higher healthcare utilization. Teaching Internal Medicine (IM) resident trainees to provide high value care for HNHC ... ...

Abstract	Objectives: High-need, high-cost (HNHC) patients represent a small proportion of patients in the US, but result in disproportionately higher healthcare utilization. Teaching Internal Medicine (IM) resident trainees to provide high value care for HNHC patients is critical. We sought to improve resident attitudes and increase clinical skills associated with treating HNHC patients by creating a curriculum that leveraged the UCLA Extensivist Program, a patient-centered medical home for HNHC patients. Methods: We developed a curriculum for PGY-2 and PGY-3 IM residents centered on caring for HNHC patients over the course of 6, 4h sessions during 1 academic year. Participants completed pre- and post-intervention surveys assessing self-rated attitudes and skills associated with caring for an HNHC patient population. Results: Twenty-one IM residents completed the curriculum and 41 were in the control group. There were no statistically significant differences in assessed attitudes and skills, but there were trends of improvement, including a decrease in participants who agreed or strongly agreed they felt overwhelmed when seeing patients for posthospital discharge follow up (45.0% pre- to 41.7% post-intervention) and an increase in participants who agreed or strongly agreed they have the skills to successfully transition HNHC patients between inpatient and ambulatory settings (20.0% pre- to 33.3% post-intervention). Participants reported better understanding of resources available to HNHC patients, effective coordination of transitions of care, and comprehensive assessment of social determinants of health. Conclusion: A curriculum to improve resident attitudes and skills associated with caring for HNHC patients was successfully implemented in an IM program at a large academic medical center. The curriculum may be adapted for other training programs; long-term training woven throughout training may be important to significantly improve resident education on how to care for HNHC patients.
Language	English
Publishing date	2024-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2798123-X
ISSN	2382-1205
ISSN	2382-1205
DOI	10.1177/23821205241246889
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Article ; Online: Economic hardships of Korean American family caregivers of persons with dementia: a mixed-methods study.

Lee, Kathy / Seo, Chang Hyun / Cassidy, Jessica / Shin, Hye-Won / Grill, Joshua D

Aging & mental health

2022 Volume 27, Issue 9, Page(s) 1762–1769

Abstract: Objectives. ...

Abstract	Objectives.
Language	English
Publishing date	2022-09-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1474804-6
ISSN	1364-6915 ; 1360-7863
ISSN (online)	1364-6915
ISSN	1360-7863
DOI	10.1080/13607863.2022.2122932
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Zs.A 5081: Show issues

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Article ; Online: Hypotension During Vasopressor Infusion Occurs in Predictable Clusters: A Multicenter Analysis.

Horiguchi, Daisuke / Shin, Sungtae / Pepino, Jeremy A / Peterson, Jeffrey T / Kehoe, Iain E / Goldstein, Joshua N / Lee, Jarone / Kwon, Brian K / Hahn, Jin-Oh / Reisner, Andrew T

Journal of intensive care medicine

2024 , Page(s) 8850666241226893

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-01-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	632828-3
ISSN	1525-1489 ; 0885-0666
ISSN (online)	1525-1489
ISSN	0885-0666
DOI	10.1177/08850666241226893
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Zs.A 2158: Show issues

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Article ; Online: Utility of preoperative MRI for assessing proximal fragment vascularity in scaphoid nonunion.

Meaike, Joshua J / Meaike, Jesse D / Collins, Mark S / Bishop, Allen T / Shin, Alexander Y

The bone & joint journal

2023 Volume 105-B, Issue 6, Page(s) 657–662

Abstract: Aims: The benefit of MRI in the preoperative assessment of scaphoid proximal fragment vascularity remains controversial. The purpose of this study is to compare preoperative MRI findings to intraoperative bleeding of the proximal scaphoid.: Methods: ... ...

Abstract	Aims: The benefit of MRI in the preoperative assessment of scaphoid proximal fragment vascularity remains controversial. The purpose of this study is to compare preoperative MRI findings to intraoperative bleeding of the proximal scaphoid. Methods: A retrospective review of 102 patients who underwent surgery for scaphoid nonunion between January 2000 and December 2020 at a single institution were identified. Inclusion criteria were: isolated scaphoid nonunion; preoperative MRI assessing the proximal fragment vascularity; and operative details of the vascularity of the proximal fragment with the tourniquet deflated. MRI results and intraoperative findings were dichotomized as either 'yes' or 'no' for the presence of vascularity. A four-fold contingency table was used to analyze the utility of preoperative MRI with 95% confidence intervals. Relative risk was calculated for subgroups to analyze the association between variables and MRI accuracy. Results: Preoperative MRI identified 55 proximal scaphoid fragments with ischaemia and 47 with vascularized proximal fragments. After the proximal fragment was prepared, the tourniquet was deflated and assessed for bleeding; 63 proximal fragments had no bleeding and 39 demonstrated bleeding. MRI was not reliable or accurate in the assessment of proximal fragment vascularity when compared with intraoperative assessment of bleeding. No patient or MRI factors were identified to have a statistical impact on MRI accuracy. Conclusion: Current preoperative MRI protocols and diagnostic criteria do not provide a high degree of correlation with observed intraoperative assessment of proximal fragment bleeding. While preoperative MRI may assist in surgical planning, intraoperative assessment remains the best means for assessing proximal fragment vascularity in scaphoid nonunion. Future efforts should focus on the development of objective measures of osseous blood flow that may be performed intraoperatively.
MeSH term(s)	Humans ; Fractures, Ununited/diagnostic imaging ; Fractures, Ununited/surgery ; Scaphoid Bone/diagnostic imaging ; Scaphoid Bone/surgery ; Magnetic Resonance Imaging ; Upper Extremity ; Retrospective Studies ; Bone Transplantation/methods
Language	English
Publishing date	2023-06-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2697156-2
ISSN	2049-4408 ; 2049-4394
ISSN (online)	2049-4408
ISSN	2049-4394
DOI	10.1302/0301-620X.105B6.BJJ-2022-0835.R2
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Article: Wound Complications with Multiple Wrist Incisions in Distal Radius Reconstruction.

Meaike, Joshua J / Athens, Christian / Sgromolo, Nicole / Shin, Alexander Y / Rhee, Peter C

Journal of wrist surgery

2021 Volume 11, Issue 4, Page(s) 316–321

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2021-10-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	2678060-4
ISSN	2163-3924 ; 2163-3916
ISSN (online)	2163-3924
ISSN	2163-3916
DOI	10.1055/s-0041-1736605
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Article: Understanding the effects of institutional diversity on irrigation systems dynamics

Shin, Hoon C. / Vallury, Sechindra / Abbott, Joshua K. / Anderies, John M. / Yu, David J.

Ecological economics. 2022 Jan., v. 191

2022

Abstract: Comparative institutional analyses of social-ecological systems (SESs) have advanced our understanding of features and performances of single institutions such as state, market, and self-organized institutions. However, such studies have hardly extended ... ...

Abstract	Comparative institutional analyses of social-ecological systems (SESs) have advanced our understanding of features and performances of single institutions such as state, market, and self-organized institutions. However, such studies have hardly extended our understanding of institutional diversity to combinations of different institutions and their joint impacts on the dynamics of SES. We address this gap by focusing on government-managed irrigation systems as a quintessential example of SESs. We developed a formal stylized model to examine how institutions affect social processes in a government-managed irrigation system. More specifically, we examine how infrastructure dynamics and farmers-agency interactions are affected under the coexistence of two institutions: groundwater market and participatory institutions. The former institutionalizes the use of private irrigation infrastructures as an exit option to the public infrastructure managed by a government agency (exit). The latter institutionalizes farmers' voicing of concerns and participation as a pressure mechanism on the agency (voice). The model results show that the joint effects of those institutions on system outcomes vary with the agency's reactions to the exit and voice. We also demonstrate that the silence option – use of neither option – is a double-edged sword. Silent farmers can impede infrastructure improvement, but in some cases, help it dramatically.
Keywords	ecological economics ; government agencies ; groundwater ; infrastructure ; irrigation systems ; markets ; models
Language	English
Dates of publication	2022-01
Publishing place	Elsevier B.V.
Document type	Article
ISSN	0921-8009
DOI	10.1016/j.ecolecon.2021.107221
Database	NAL-Catalogue (AGRICOLA)

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